• 약학회지
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• 제54권5호
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• pp.377-386
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• 2010

Single-dimensional (1-D) and two-dimensional (2-D) LC methods were utilized to separate peptides from various sources followed by MS/MS analysis. Two-dimensional ultra-high performance liquid chromatography is a useful tool for proteome analysis, providing a greater peak capacity than 1-D LC. The most popular 2-D LC approach used today for proteomic research combines strong cation exchange and reversed-phase LC. We have evaluated an alternative mode for 2-D LC of peptides using 2-D RP-RP nano UPLC Q-TOF Mass Spectrometry, employing reversed-phase columns in both separation dimensions. As control experiments, we identified 129 proteins in 1-D LC and 322 proteins in 2-D LC from E. coli extract peptides. Furthermore, we applied this method to rat primary hepatocyte and a total of 170 proteins were identified from 1-D LC, and 527 proteins were identified from all 2-D LC system. The in-depth protein profiling established by this 2-D LC MS/MS from rat primary hepatocyte could be a very useful reference for future applications in regards to drug induced liver toxicity.

• 한국광학회:학술대회논문집
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• 한국광학회 2002년도 제13회 정기총회 및 2002년도 동계학술발표회
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• pp.158-159
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• 2002

• Journal of Information Display
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• 제12권3호
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• pp.121-124
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• 2011

The mechanism for lattice-shaped mura defects was proposed by characterizing the electro-optic properties of liquid crystal (LC), which showed different transmission properties between the normal and mura defect areas. An increase in the mura defect rate was observed when the dotted LC in the one drop filling (ODF) was exposed for a longer time. The dotted LC droplet at the edge evaporated more rapidly than that in the center. This resulted in a higher concentration of polar singles at the edge of the dotted LC droplet, leading to a higher ${\Delta}n$ value and higher transmittance. This implies that the reductio of the exposure time of the dotted LC to air plays a critical role in decreasing the occurrence of lattice-shaped mura defects in ODF.

• 한국광학회:학술대회논문집
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• 한국광학회 2000년도 제11회 정기총회 및 00년 동계학술발표회 논문집
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• pp.118-119
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• 2000

최근에 많이 사용되는 휴대용기기의 표시장치인 액정표시장치를 보면 반사형 액정표시장치가 많이 사용되고 있다. 반사형 액정표시장치는 표시장치의 전력소모의 많은 부분을 차지하는 backlight 를 주변 광원으로 대체하여 전력소모를 줄일 수 있는 표시장치로서 많이 연구되고있다. 최근에 연구되고있는 반사형 표시장치를 살펴보면 반사형 TN (Twisted Nematic) LC 모드가 주류를 이루고 있으나 콘트라스트비가 낮은 단점이 있다$^{[1]}$ . 이를 극복하기 위하여 반사형 VA (Vertical Aligned) LC 모드가 제시되어진다. VA LC 모드는 TN LC 모드와 반대로 음의 유전율 이방성을 가지는 액정물질을 이용하여 유리기판에 수직으로 배향시킨 모드로서, 전압이 인가되지 않은 초기상태에는 액정 cell 이 복굴절을 전혀 나타내지 않는다. TN LC 모드와 정확히 역의 구조를 가진다. 그리하여 초기상태에서 편광판 한 장과 광대역 λ/4 위상지연판을 사용하여 뛰어난 어두운 상태를 구현할 수가 있다. (중략)

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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• pp.1179-1181
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• 2004

We have studied a single gap transflective liquid crystal display (LCD) associated with in-plane switching (IPS) mode. In the transmissive IPS cell, the transmittance of electrodes and above electrodes is different, that is, the degree of rotation of the LC director between electrodes and above electrodes is 45 $^{\circ}$ and 22.5 $^{\circ}$ , respectively. Utilizing the different rotating angle of the LC director and in-cell retarder with a quarter-wave plate used below the LC layer, the IPS transflective LCD is realized such that the area between electrodes is used as a transmissive part and the area above electrodes is used as a reflective part.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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• pp.294-297
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• 2006

Using a single LC panel and two lighting systems, we have developed an advanced LCD system called "Double-Sided LCD." It has only one LC panel and two lighting systems, but it can display images of the same size and resolution on both the front and the rear side. Furthermore, utilizing a simple and thin lighting system we have reduced dramatically its module thickness up to 3.0mm, much thinner than that of conventional dual-type LCD, which is quite appropriate for the use of mobile applications.

• 한국광학회지
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• 제12권6호
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• pp.468-471
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• 2001

본 논문에서는 회전 편광자법을 이용한 액정셀의 셀갭측정 방법을 개선하여 반사모드의 TN LCD의 셀갭을 측정할 수 있는 방법을 제안하였다. 측정 시스템에서 액정셀(liquid crystal cell)을 회전시키며 분산 특성을 측정하여, 액정 꼬임각이 알려진 셀의 갭과 파장에 따른 Δnd값을 구할 수 있다.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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• pp.167-177
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• 2004

본 논문에서는 LC/MS 데이터로부터 동위 원소 패턴(isotope pattern)을 찾는 새로운 방법을 제시하고자 한다. 기존의 분석 방법에서는 LC/MS 데이터를 1차원적으로 분석하고 있기 때문에 2차원에서 적용할 수 있는 알고리즘을 적용하기가 어렵다. LC/MS 데이터를 2차원 영상으로 가시화해 본 결과, 하나의 동위 원소 패턴에 속하는 단일 동위 원소 피크(single isotope peak)는 모양, 크기와 같은 2차원 형태적 특징들도 유사함을 알 수 있다. 따라서, 기존의 방법들이 질량 스펙트럼과 같은 1차원 신호를 분석하는 것에 중점을 둔 것에 비해, 본 논문에서는 LC/MS 데이터를 2차원 신호 즉, 영상(image)으로 간주하고 영상 처리 방법과 객체 인식 방법을 적용하였다. 실험 결과 같은 동위 원소 패턴에 속하는 각각의 단일 동위원소 피크들 사이에 peak maxima position 뿐만 아니라 skewness, variance등도 유사였으며 이러한 유사도를 기반으로 동위 원소 패턴을 찾을 수 있었다.

• 한국전기전자재료학회논문지
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• 제17권5호
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• pp.536-540
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• 2004

A novel nematic liquid crystal (LC) cell with splay structure exhibiting wide viewing angle, fast response time and high transmittance at the same time has been developed. With rubbed homeotropic alignment in parallel directions, the device shows bend alignment in the absence of vertical electric field. However, with applied high voltage in a pulse form, the LC shows a optically compensated splay (OCS) orientation such that the mid-director is parallel to a substrate and at both surfaces the LCs are aligned vertically in parallel direction. In the device, the birefringence of the cell becomes tunable with applying voltage, i.e., the amount of light passed through the cell can be controlled by controlling the orientation of the LC. Since the OCS cell has a self-compensation structure such that the LC has a mirror symmetry along the mid-director, the device shows a wide viewing angle with only a single domain and a fast response time.

• Journal of Information Display
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• 제12권3호
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• pp.115-119
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• 2011

Optically isotropic liquid crystal (LC) mixture such as blue-phase LC and nanostructured LC composites exhibit the advantages of fast response time, high contrast ratio and wide-viewing angle due to the induced birefringence along the horizontal electric field. Utilizing this mixture, a novel single cell gap in-plane switching-type polymer-stabilized blue-phase transflective liquid crystal display by embedding the nanowire grid polarizer as a polarization-dependent reflective polarizer in the R region is proposed. This device can be used as a normal black mode without any quarter-wave plate or patterned in-cell phase retarder. Moreover, the transmittance is identical to the reflectance so that it will be suitable for single gamma driving. Detailed electro-optic performances, such as voltage-dependent light efficiency and viewing angle of the proposed device configuration, are investigated.