• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.5
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• pp.506-513
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• 2015

In this paper, we proposed a novel ethanol concentration sensor using microfluidic metamaterial absorber. The metamaterial absorber comprises a split-ring-cross resonator(SRCR) and a microfluidic channel. The SRCR can generate LC resonance that is very sensitive to changes in the effective dielectric constant around the capacitive gap. In addition, microfluidic channels can change the effective dielectric constant of the dielectric substrate by using an infinitesimal quantity of a liquid on the order of microliters. The proposed absorber can detect the electrical properties of different concentration of ethanol. The performance of the proposed absorber is demonstrated using the absorption measurements of a fabricated prototype sample with waveguides. In addition, the simulated results and measurement results show good agreement.

• Journal of the Korean Society of Radiology
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• v.11 no.7
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• pp.589-595
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• 2017

This study evaluated the effect of gadolinium contrast agents on the spectrum of metabolites during $^1H-MRS$ of brain and to investigate whether the contrast agents injected before MR spectroscopy significantly affect the estimated peaks of MRS. From January to May 2017, brain MR spectroscopy was performed on 30 patients to compare the spectrum before and after contrast injection of the brain white matter tissue. As a result, the spectrum of metabolites decreased after the paramagnetic contrast agents injected. However, it was not statistically significant which indicated that the use of contrast agent did not meaningfully affect the spectrum of metabolites. In conclusion, the use of the paramagnetic contrast before the acquisition of the spectroscopy may aid voxel positioning especially when it is difficult to determine the exact location of the lesion or the contrast is low.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.8
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• pp.933-939
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• 2008

In this paper, a new composite electromagnetic bandgap(EBG) structure using magnetic materials is proposed for simultaneous switching noise(SSN) suppression in the high-speed digital circuits. The proposed EBG structure has periodic unit cells of square-patches connected by spiral-shaped bridges. The magnetic materials are located on the unit cells of spiral-shaped EBG. The real part of the permeability shifts bandgap to the lower frequency region due to the increased effective inductance. The imaginary part of the permeability has magnetic loss that decreases parasitic LC resonance peaks from between the unit cells. As a result, the proposed structure has the lower cut-off frequency compared with conventional EBG structure and -30 dB SSN suppression bandwidth from 175 MHz to 7.7 GHz. The proposed structure is expected to improve the power integrity and reduce the size of the EBG power plane.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.11 no.6
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• pp.976-983
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• 2000

In this paper, Bridcage type RF coils used widely as RF coils for MRI and its applicable type, spiral type RF coil are analyzed and designed using FDTD method. In low tesla (IT, 1.5T) MRI system, several tools have been used for the analysis and design of the RF coils for MRI. This includes, so-called, LC equivalent circuit method for predicting the resonance frequency of the coil and the Biot-Savart law to determine the field distribution within the coil. Both of the circuit analysis and Biot-Savart law are low frequency techniques. Therefore, at high frequency applications, the circuit model approximation breaks down because the coil geometry is a significant fraction of the wavelength. In this paper, we analyzed and designed RF coils for 3T MRI using FDTD method. This method is a full wave analysis and very accurate at low and high frequencies. Also, this RF coils are actually fabricated and FDTD models of RF coils for MRI are proven.

• The Transactions of the Korean Institute of Power Electronics
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• v.10 no.4
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• pp.356-362
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• 2005

In this paper, in order to develop a simple and high efficient ballast without an external ignitor, a half-bridge type ballast with a coupled inductor and a frequency controlled synchronous rectifier is proposed. The Internal LC resonance of the buck converter is used to generate a high voltage pulse for the ignition, and the coupled inductor filter is used for steady state ripple cancellation. Also, a synchronous buck converter is applied for the DC/DC converter stage. In order to improve the efficiency of the ballast, a frequency control method is proposed. This scheme reduces a circulation current and trun off loss of the MOSFET switch on the constant power operation, which results in increase of the efficiency of the ballast system about 4$\%$, compared to a fixed frequency control. It consists a 2-stage version ballast with a PFC circuit. The results are verified nth hardware experiments.

• Journal of Microbiology and Biotechnology
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• v.34 no.3
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• pp.725-734
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• 2024

CYP102A1 from Bacillus megaterium is an important enzyme in biotechnology, because engineered CYP102A1 enzymes can react with diverse substrates and produce human cytochrome P450-like metabolites. Therefore, CYP102A1 can be applied to drug metabolite production. Terpinen-4-ol is a cyclic monoterpene and the primary component of essential tea tree oil. Terpinen-4-ol was known for therapeutic effects, including antibacterial, antifungal, antiviral, and anti-inflammatory. Because terpenes are natural compounds, examining novel terpenes and investigating the therapeutic effects of terpenes represent responses to social demands for eco-friendly compounds. In this study, we investigated the catalytic activity of engineered CYP102A1 on terpinen-4-ol. Among CYP102A1 mutants tested here, the R47L/F81I/F87V/E143G/L188Q/N213S/E267V mutant showed the highest activity to terpinen-4-ol. Two major metabolites of terpinen-4-ol were generated by engineered CYP102A1. Characterization of major metabolites was confirmed by liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS, and nuclear magnetic resonance spectroscopy (NMR). Based on the LC-MS results, the difference in mass-to-charge ratio of an ion (m/z) between terpinen-4-ol and its major metabolites was 16. One major metabolite was defined as 1,4-dihydroxyp-menth-2-ene by NMR. Given these results, we speculate that another major metabolite is also a mono-hydroxylated product. Taken together, we suggest that CYP102A1 can be applied to make novel terpene derivatives.

• Journal of the Korean Magnetic Resonance Society
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• v.19 no.2
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• pp.67-73
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• 2015

The microcystin is a cyclic heptapeptide from metabolites of cyanobacteria in the genera mycrocystis, anabaeba as a result of eutrophication. It has been known that microcystin-LR is a potent inhibitor of the catalytic subunits of protein phosphatase-1 (PP-1) as well as powerful tumor promoter. The active site of microcystin actually has two metal ions $Fe^{2+}/Zn^{2+}$ close to the nucleophilic portion of PP-1-microcystin complex. We report the isolation and purification of this microcystin-LR from cyanobacteria (blue-green algae) obtained from Daechung Dam in Chung-cheong Do, Korea. Microcystin-LR was extracted from solid-phase extraction (SPE) sample preparation using a CN cartridge. The cyanobacteria extract was purified to obtain microcystin-LR by HPLC method and identified by LC/MS. The detail structural studies that can elucidate the possible role of monovalent and divalent metal ions in PP-1-microcystin complexation were carried out by utilizing molecular dynamics. Conformational changes in metal binding for ligands were monitored by molecular dynamic computation and potential of mean force (PMF) using the method of the free energy perturbation. The microcystin-metal binding PMF simulation results exhibit that microcystin can have very stable binding free energy of -10.95 kcal/mol by adopting the $Mg^{2+}$ ion at broad geometrical distribution of $0.5{\sim}4.5{\AA}$, and show that the $K^+$ ion can form a stable metal complex rather than other monovalent alkali metal ions.

• The Transactions of the Korean Institute of Power Electronics
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• v.7 no.1
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• pp.30-40
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• 2002

This paper studies the electronic ballast development for 250w MH lamps. We have improved the input power factor using a PFC IC. To provide the rating voltage required In the lamps, we have used the buck type dc-dc converter By this method, the stress of switching devices in inverter can be reduced. The inverter is the Full-Bridge type. To eliminate the acoustic resonance phenomena of MH lamps, we have added the high frequency sinewave voltage to the low frequency square-wave voltage to the lamp. We hove developed the igniter circuit using the L, C devices. We could control dimming of the lamp by varying the output voltage of the buck converter. The time of illuminating lamps and luminous intensity could be adjusted by season and time band. The buck converter output voltage can be controlled and the no load and over current situation were Protected by the development of the microprocessor Program.

• The Transactions of the Korean Institute of Power Electronics
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• v.15 no.2
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• pp.150-158
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• 2010

The operational characteristics of a resonant DC/DC converter, which can harvest thermoelectric energy, is analyzed, depending on the relative magnitudes of the input voltage and the load voltage. The resonant converter consists of LC resonant circuit connected to DC input source and a resonant pulse converter in which the input energy is transferred to the load as the resonant capacitor voltage is peak. The resonant capacitor doubles the input voltage by the resonance phenomenon. By the relative magnitude between the input voltage and the output voltage, the resonant DC/DC converter operates in three different modes. For boost mode, the peak voltage of the resonant capacitor is smaller than the load voltage. For hybrid mode, the peak voltage of the resonant capacitor is bigger than the load voltage and every switching period has both the boost mode and the direct mode. For the direct mode, the input voltage is bigger than the load voltage and the converter transfers directly the input energy to the load without the switching operation. Operation principles and the feasibility of the converter for the thermoelectric energy harvesting are verified with PSPICE simulation and experiment.

• Journal of electromagnetic engineering and science
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• v.16 no.3
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• pp.194-197
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• 2016

An eight-element compact low-profile multi-input multi-output (MIMO) antenna is proposed for wireless local area network (WLAN) mobile applications. The proposed antenna consists of eight inverted-F antennas with an isolation-enhanced structure. By inserting the isolation-enhanced structure between the antenna elements, the slot and capacitor pair generates additional resonant frequency and decreases mutual coupling between the antenna elements. The overall size of the proposed antenna is only $33mm{\times}33mm$, which is integrated into an area of just $0.5{\lambda}{\times}0.5{\lambda}$. The proposed antenna meets 5-GHz WLAN standards with an operation bandwidth of 4.86 - 5.27 GHz and achieves an isolation of approximately 30 dB at 5 GHz. The simulated and measured results for the proposed antenna are presented and compared.