• Title/Summary/Keyword: LAT

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Induction of Growth Inhibition by BCH in KB Human Oral Epidermoid Carcinoma Cells (구강 편평세포암종 KB세포에서 아미노산 수송억제제 BCH에 의한 세포성장 억제)

  • Yoon, Jung-Hoon;Kim, Youn-Bae;Kim, Do-Kyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.5
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    • pp.758-763
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    • 2003
  • Amino acid transporters play an important role in supplying nutrients to normal and cancer cells for cell proliferation. System L is a major transport system responsible for the N $a^{+}$-independent, large neutral amino acids including several essential amino acids. L-type amino acid transporter 1 (LAT1), an isoform of system L amino acid transporter, is highly expressed presumably to support their continuous growth and proliferation in malignant tumors. 2-Aminobicyclo- (2,2,1) -heptane-2-carboxylic acid (BCH) is a model compound for study of amino acid transporter as a system L selective inhibitor. In the present study, we examined whether BCH induced growth inhibition in KB human oral squamous carcinoma cell line or not. The uptake of L-[$^{14}$ C]leucine by KB cells is inhibited by BCH in a concentration dependent manner with a Ι $C_{50}$ value of 75.3$\pm$6.2 ${\mu}{\textrm}{m}$ and a $K_{i}$ value of 98.7$\pm$ 4.1 ${\mu}{\textrm}{m}$. The growth of KB cells is inhibited by BCH in time dependent manner and concentration dependent manner with a Ι $C_{50}$ value of 11.1 $\pm$0.8 mM. In the DNA of KB cells treated with the various concentrations and various periods of BCH, the characteristic ladders associated with DNA fragmentation were not observed. These results suggest that BCH inhibits the growth of KB oral epidermoid carcinoma cells through the inhibition of transport of neutral amino acids into cells without DNA break down. This phenomenon will be a new rationale for anti-cancer therapy.y.

Relationship Between the Catches and the Water Temperature of Tuna in the Pacific Ocean - The Operating Results of M . S #27 Cheng Rong at Eastern Fishing Ground of Tropical Rigion - (태평양 다랑어 어장의 어획량과 수온과의 관계-청룡 제27호의 열대해역 동부어장에서의 조업결과-)

  • 김광홍
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.32 no.1
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    • pp.24-32
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    • 1996
  • This paper described on relation between the catches of tuna and the distribution of water temperature of eastern fishing ground of Tropical region in the Pacific Ocean. The data of catches and water temperature used in this paper were based log book which # 27 CHENG RONG(Gross tonnage : 399 ton) had been worked eastern fishing ground(Lat : 09$^{\circ}$N- 14$^{\circ}$S, Long : 115$^{\circ}$- 149$^{\circ}$W)from January to October, 1991. The obtained result are as follows : 1. On the relation between the catches and the geographical distribution, bigeye tuna was higher catches at Lat 4$^{\circ}$- 9$^{\circ}$N, Long 135$^{\circ}$- 139$^{\circ}$W area in the equatorial counter current region where surface water temperature was range of 27.5$^{\circ}C$ to 27.9$^{\circ}C$, yellowfin tuna was higher catches at Lat 4$^{\circ}$- 9$^{\circ}$S, Long 145$^{\circ}$- 149$^{\circ}$W in the south equatorial current region where surface water temperature was range of 28.$0^{\circ}C$ to 28.4$^{\circ}C$ and albacore tuna was higher catches at Lat 10$^{\circ}$- 14$^{\circ}$S, Long 120$^{\circ}$- 124$^{\circ}$W area in the south equatorial current region where surface temperature was range of 26.5$^{\circ}C$ to 26.9$^{\circ}C$ 2. On the relation between catches and distribution of vertical water temperature, bigeye tuna was higher catches at the water temperature of 1$0^{\circ}C$ to 12$^{\circ}C$ on depth layer between 300m and 360m, yellowfin tuna was higher catches at the water temperature of 15$^{\circ}C$ to 19$^{\circ}C$ on depth layer between 180m and 280m and albacore tuna was higher catches at the water temperature of 12$^{\circ}C$ to 14$^{\circ}C$ on depth layer between 280m and 310m. Above the result, it seemed that bigeye tuna distributed deeper layer than yellowfin and albacore tuna.

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Gamma-ray Emission from Globular Clusters

  • Tam, Pak-Hin T.;Hui, Chung Y.;Kong, Albert K. H.
    • Journal of Astronomy and Space Sciences
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    • v.33 no.1
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    • pp.1-11
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    • 2016
  • Over the last few years, the data obtained using the Large Area Telescope (LAT) aboard the Fermi Gamma-ray Space Telescope has provided new insights on high-energy processes in globular clusters, particularly those involving compact objects such as MilliSecond Pulsars (MSPs). Gamma-ray emission in the 100 MeV to 10 GeV range has been detected from more than a dozen globular clusters in our galaxy, including 47 Tucanae and Terzan 5. Based on a sample of known gammaray globular clusters, the empirical relations between gamma-ray luminosity and properties of globular clusters such as their stellar encounter rate, metallicity, and possible optical and infrared photon energy densities, have been derived. The measured gamma-ray spectra are generally described by a power law with a cut-off at a few gigaelectronvolts. Together with the detection of pulsed γ-rays from two MSPs in two different globular clusters, such spectral signature lends support to the hypothesis that γ-rays from globular clusters represent collective curvature emission from magnetospheres of MSPs in the clusters. Alternative models, involving Inverse-Compton (IC) emission of relativistic electrons that are accelerated close to MSPs or pulsar wind nebula shocks, have also been suggested. Observations at >100 GeV by using Fermi/LAT and atmospheric Cherenkov telescopes such as H.E.S.S.-II, MAGIC-II, VERITAS, and CTA will help to settle some questions unanswered by current data.

Restricting Answer Candidates Based on Taxonomic Relatedness of Integrated Lexical Knowledge Base in Question Answering

  • Heo, Jeong;Lee, Hyung-Jik;Wang, Ji-Hyun;Bae, Yong-Jin;Kim, Hyun-Ki;Ock, Cheol-Young
    • ETRI Journal
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    • v.39 no.2
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    • pp.191-201
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    • 2017
  • This paper proposes an approach using taxonomic relatedness for answer-type recognition and type coercion in a question-answering system. We introduce a question analysis method for a lexical answer type (LAT) and semantic answer type (SAT) and describe the construction of a taxonomy linking them. We also analyze the effectiveness of type coercion based on the taxonomic relatedness of both ATs. Compared with the rule-based approach of IBM's Watson, our LAT detector, which combines rule-based and machine-learning approaches, achieves an 11.04% recall improvement without a sharp decline in precision. Our SAT classifier with a relatedness-based validation method achieves a precision of 73.55%. For type coercion using the taxonomic relatedness between both ATs and answer candidates, we construct an answer-type taxonomy that has a semantic relationship between the two ATs. In this paper, we introduce how to link heterogeneous lexical knowledge bases. We propose three strategies for type coercion based on the relatedness between the two ATs and answer candidates in this taxonomy. Finally, we demonstrate that this combination of individual type coercion creates a synergistic effect.

Notes on Powdery Mildew of Dahlia in Korea (다알리아 흰가루병균에 관한 소고)

  • Shin, Hyeon-Dong;Lee, Hyun-Tae
    • The Korean Journal of Mycology
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    • v.27 no.3 s.90
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    • pp.234-236
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    • 1999
  • Sphaerotheca fuliginea has previously been recorded as a powdery mildew fungus on dahlia (Dahlia pinnata) in Korea. Six collections of the dahlia mildew by the authors since 1993, however, show that the fungus does not contain conspicuous fibrosin bodies and has sinuate edge lines on conidiophores. These characters clearly indicate that the fungus causing the powdery mildew on dahlia in Korea is Erysiphe cichoracearum. On the other hand, one plant of dahlia grown in a pot was found to be infected with S. fusca (= S. fuliginea s. lat.). It is supposed to be unusual. Therefore, two species of dahlia mildew fungi are distributed and E. cichoracearum is the main cause of dahlia mildew in Korea.

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The Influence of Trunk Rotation Exercise and PNF Exercise on Gait in the Individuals with Malalignment Syndrome (체간 양측성 회전 운동과 PNF 운동이 부정렬 증후군을 가진 성인의 보행에 미치는 영향)

  • Choi, Jae-Won;No, Hyun-Jeung
    • PNF and Movement
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    • v.9 no.4
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    • pp.49-55
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    • 2011
  • Purpose : The aim of this study was to identify of bilateral trunk rotation(BTR) exercise and PNF exercise on gait in the individuals with malalignment syndrome. Methods : Subjects were 32 that were divided 2 groups in 20's generation. Interventions were trunk ratation exercise and PNF exercise. We used Medex for trunk rotation exercise. BTR group received exercise for three-sets (10min/set) along with stretching exercise ten-minutes, 3 times per week. PNF group took turns the D1 pattern in upper extremity and the D1 pattern in the opposite side of lower extremity for three-sets (10min/set). The measurement were force metatarsal 1 (FM 1), impulse metatarsal 1 (IM 1), force heel lat (FHL), impulse heel lat (IHL) by using footscan (RS scan). Statistical method was repeated measurement of ANOVA and p value was 0.05. Results : BTR and PNF group were significantly different in time(FM 1, IM 1, FHL, IHL). As different of right/left, BTR and PNF exercise were significantly different in FM 1, IM 1, FHL. Conclusion : BTR exercise was good exercise for malalignment but needs expensive equipment, for example, Medex. PNF exercise doesn't need expensive equipment but good method in malalignment syndrome person for gait ability. If PNF exercise is more experiment, PNF exercise could use variety for more patients.

ON LOCAL SPECTRAL PROPERTIES OF RIESZ OPERATORS

  • JONG-KWANG YOO
    • Journal of applied mathematics & informatics
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    • v.41 no.2
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    • pp.273-286
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    • 2023
  • In this paper we show that if T ∈ L(X) and S ∈ L(X) is a Riesz operator commuting with T and XS(F) ∈ Lat(S), where F = {0} or F ⊆ ℂ ⧵ {0} is closed then T|XS(F) and T|XT(F) + S|XS(F) share the local spectral properties such as SVEP, Dunford's property (C), Bishop's property (𝛽), decomopsition property (𝛿) and decomposability. As a corollary, if T ∈ L(X) and Q ∈ L(X) is a quasinilpotent operator commuting with T then T is Riesz if and only if T + Q is Riesz. We also study some spectral properties of Riesz operators acting on Banach spaces. We show that if T, S ∈ L(X) such that TS = ST, and Y ∈ Lat(S) is a hyperinvarinat subspace of X for which 𝜎(S|Y ) = {0} then 𝜎*(T|Y + S|Y ) = 𝜎*(T|Y ) for 𝜎* ∈ {𝜎, 𝜎loc, 𝜎sur, 𝜎ap}. Finally, we show that if T ∈ L(X) and S ∈ L(Y ) on the Banach spaces X and Y and T is similar to S then T is Riesz if and only if S is Riesz.

An Efficient Future Indexing Technique for the Moving Object Location Prediction System (이동 객체 위치 예측 시스템을 위한 효율적인 미래 인덱싱 기법)

  • Lee, Kang-Joon;Kim, Joung-Joon;Han, Ki-Joon
    • 한국공간정보시스템학회:학술대회논문집
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    • 2007.06a
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    • pp.3-8
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    • 2007
  • 최근 도로 네트워크 환경에서 이동 객체 위치 정보를 관리하고 이동 객체의 미래 위치를 예측하는 이동 객체 위치 예측 시스템의 필요성이 나날이 증가되고 있다. 이동 객체위치 예측 시스템은 교통 관제 및 다양한 응급 상황 시 이동 객체의 미래 위치를 신속히 예측하기 위해 사용되며, 보다 편리한 위치 기반 서비스의 제공을 가능하게 해준다. 이러한 시스템을 위한 대부분의 미래 인덱싱 기법은 일반적으로 이동 객체의 미래 위치 예측을 위해 과거 이동 궤적을 이용하고 있다. 그러나, 수많은 이동 객체의 과거 이동 궤적 관리가 어렵고, 실시간으로 변화하는 이동 객체의 미래 궤적을 반영하기 위한 방대한 미래 인덱스의 갱신 요청으로 인해 인덱스 유지 비용이 증가하여 미래 위치 질의 요청에 대한 신속한 처리 성능이 떨어지게 된다. 따라서 본 논문에서는 이동 객체 위치 예측 시스템에서 방대한 이동 객체의 과거 이동 궤적으로부터 효율적으로 미래 위치를 예측하기 위해 셀 기반의 미래 인덱싱 방법인 PFCT-Tree(Probability Future Cell Trajectory-Tree)를 제시한다. PFCT-Tree는 방대한 과거 이동 궤적을 셀 단위로 재구성하여 인덱스 크기를 줄이고, 셀 내부 경험치를 기반으로 장기간 질의 시 빠른 미래 위치를 예측할 수 있다. 또한 신속한 미래 이동 궤적의 갱신 속도를 향상시키기 위해 미래 시간을 미래 궤적과 분리하여 인덱싱함으로써 위치 예측 오류로 인한 미래 인덱스 갱신 비용을 최소화 할 수 있다. 마지막으로 실험을 통해 도로 네트워크 환경에서 PFCT-Tree가 기존 인덱싱 기법들보다 갱신 및 검색 성능이 우수함도 입증하였다.ential oil (Bergamot, Grapefruit, Lemon, Petigrain)은 농도 의존적으로 ROS 생성을 증가시켰다. 이상의 결과를 종합하여 볼 때 citrus essential oil은 MSH에 의한 melanin 생성을 억제하는 것으로 보아 미백제로서의 개발 가능성이 있는 것으로 사료된다.가 사용될 수 있음을 제시한다.찍 발견되어 크기는 작았으며, 육안적으로 폴립의 Yamada 형태의 분류는 II, III의 형태를 띠고 있었다.EX>로 한반도 후기 백악기의 고지자기극$(Lat./Long.=70.9^{\circ}N/215.4^{\circ}E,\;A_{95}=5.3^{\circ})$의 위치와 유사하므로 암석의 생성 시기는 후기 백악기로 판단하였다. 한편 함평분지에 분포하는 백악기 화산암류에서는 한 개의 정자화 방향과 두 개의 역자화 방향이 확인되었다. 이들 특성잔류자화 방향은 백악기 화산암 형성 당시 암석에 기록된 성분으로써 당시 지구자기장의 상태를 기록한 것으로 해석하였으며, 이중 정자화 방향을 함평분지 화산암의 대표 방향으로 채택하였다 함평분지 화산암의 고지자기 극의 위치는 정자극의 경우는 $Lat./Long.=70.2^{\circ}N/199.5^{\circ}E,\;(K=18.1,\;A_{95}=9.6^{\circ})$ 이며 역자극의 경우는 $Lat./Long.=65.5^{\circ}S/251.3^{\circ}E,\;(K=7.1,\;A_{95}=20.7^{\circ})$이다. 이중 정자극의 위치는 한반도의 후기 백악기극의 위치와 통계적으로 동일한 것으로 나타나 함평분지 화산암

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Changes of Pharyngeal Airway Space after Mandibular Setback Surgery in Computed Tomography Images (전산화단층촬영상에서 하악후퇴수술 후 인두기도 공간의 변화)

  • Kim, Bang-Sin;Jung, Seung-Gon;Han, Man-Seung;Jeoung, Youn-Wook;Kook, Min-Suk;Park, Hong-Ju;Oh, Hee-Kyun;Ryu, Sun-Youl
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.1
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    • pp.36-43
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    • 2011
  • Purpose: This study evaluated the pharyngeal airway space changes in CT images in patients receiving bilateral sagittal split osteotomy (BSSRO) for the surgical correction of mandibular prognathism. Methods: A total of 22 patients with mandibular prognathism were treated using BSSRO. Computed tomography was performed 1 month (T0) before surgery and, 1 month after surgery (T1). The anteroposterior length (AP), lateral width (LAT) and cross-sectional area (AREA) at the level of soft palate (C2) and base of the tongue (C3) were measured using CT images. Results: The mean amount of mandibular setback was 7.41 mm (${\pm}$3.46 mm). All the AP, LAT and AREA at the C2 and C3 level were decreased significantly 1 month after surgery (P<0.001). As the amount of mandibular setback was increased, the AP, LAT and AREA levels at the level of C2 and C3 had decreased. In addition, the reduction of the AREA at the C3 level was associated with the amount of mandibular setback (P<0.05). Conclusion: A significant decrease in pharyngeal airway space was observed 1 month after the operation. The cross-sectional area at the level of base of tongue was decreased with increasing amount of mandibular setback.

A Study on the Usefulness of Copper Filters Made with 3D Printers in Longbone Examination Using Long Length Detector (장골 검출기를 이용한 장골 검사에서 3D 프린터로 제작한 구리 필터의 유용성 연구)

  • Kim, Woo-Young;Seo, Hyun-Soo;Han, Bong-Ju;Yoon, Myeong-Seong;Lee, Young-Jin
    • Journal of radiological science and technology
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    • v.44 no.6
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    • pp.607-613
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    • 2021
  • Long-bone examination is mainly used for inspection of the lower extremities. Recently, a long length detector (FXRD-1751S, VIEWORKS, Korea) with three digital detectors attached has been developed. High energy X-rays are used because pelvic areas require high image quality. In this case, X-rays are transmitted a lot in thin areas such as an ankle, and it is not suitable for diagnosing an image. Therefore, this study use copper filters made with 3D printers to increase image quality in the Long-bone inspection. A copper filter was manufactured in consideration of the overall thickness of the lower part. The experiment was conducted in anterior-posterior (AP) and lateral (LAT) positions, depending on the presence or absence of the filter. 5x5 pixels of region of interest (ROI) were selected from the pelvis, knee, and ankle areas. X-rays were irradiated under the conditions of 70 kVp and 40 mAs for AP, 80 kVp, and 63 mAs for lat when without filters, 90 kVp and 80 mAs for AP, 90 kVp and 100 mAs for lat when with filters. signal to noise ratio(SNR) ratio and contrast to noise (CNR) values were measured 1106.38, 14.34 before applying the filter and 1189.32, 70.43 after the filter. For the knee area, 650.44, 97.61 before applying the filter, and 1013.17, 444.24 after applying the filter. For the ankle area, 206.65, 23.68 before applying the filter and 993.50, 136.11 after applying the filter. In the Long-bone examination, SNR and CNR were greatly measured when the filter was applied, confirmed the availability of using the copper additional filter.