• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.10a
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• pp.289-292
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• 2007

An object color identification and classification embedded system realization for uninhabited stock management is presented in this paper. The embedded system is realized by using ultrasonic sensor to extract the object and distance, and detecting binary image from USB CCD camera. The algorithm is identified by comparing the reference pattern with the color pattern of input image, and move to the settled rack at the store. The experimental result leads to use the uninhibited stock management with practice as a robot.

• Journal of Surface Science and Engineering
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• v.27 no.6
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• pp.340-346
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• 1994

The method of uniforming current distribution in Hull cell are studied by using auxiliary anode, current shield bipolar electrode, and combinings bipolar electrode with current shield in order to find a way of uni-form deposition. The current density distributions are measured by each ammeter of the same inner resistance connected to divided cathode pannel respectively. The current density distributions of cathode electrode divided into five sections with 5mm width have a tendency of linear inclination, and that of twenty sections have a tendency of smoother curve than the curve of original Hull cell pannel. Their results showed lower value on the high current density portion and higher value on the low portion than that original Hull cell pannel. The current distribution in Hull cell is able to unify by using auxiliary anode, or combining bipo-lar electrode with current shield, but not efficient in using one of both individually.

• Archives of Pharmacal Research
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• v.11 no.4
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• pp.308-311
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• 1988

Nine coumarin dervatives were examined for thier inhibitory effects on bovine lens aldose reductase activity (bovine-LAR). More than 50% inhibition of BLAR activities was observed in the cases of treatments with decursin, decursinol, esculin, isoimperatorin, oxypeucedanine and isobergapten at the concentration of $10^{-4}$M. Especially, BLAR activity was completely inhibited by the treatment of decursin and decursinol at this concentration. At $10^{-5}$ M, only three coumarins-decursin, decursinol and isoimperatorin, were found to have still relatively higher inhibitory effect.

• 전기의세계
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• v.34 no.1
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• pp.19-23
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• 1985

LQG로 설계된 시스템이 LQR의 보증된 안정감도를 갖도록 $K_{f}$를 조정하는 한 LTR기법을 살펴보았다. q가 0이라면 필터는 실제의 프로세서 잡음의 Q = Q$_{0}$라는 점에서 최적이다. 그러나 q의 값이 증가함에 따라 $K_{f}$는 증가되고 x over ^에 따라서 시스템의 동특성은 관측에 의해 수정되는 항보다 상대적으로 소홀히 취급되어진다. 따라서 출력 y에 포함되어 지지않는 x의 추정치 xover^은 그 실제값과 차이가 많이 나타날 우려가 생긴다. 또한 관측잡음이 xover^에 크게 영향을 미치므로 잡음을 배척하는 필터의 성질도 모호해질 우려가 있다. 그러나 안정강도의 관점에서는 크게 개선되어진다는 것을 알 수 있다. 실제 설계에 있어서는 이 장점과 단점들을 잘 trade off시키는 단계가 필요할 것이다. 또한 추정치 xover^를 얻는데 정상상태의 칼만 필터를 이용하지 않고 극배치(Pole Placement)방법을 사용함도 고려할 수 있으며 이에 따른 LTR도 흥미있는 분야가 될 수 있을 것이다.다.

• Journal of Pharmaceutical Investigation
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• v.21 no.2
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• pp.103-110
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• 1991

Two new prodrugs of lonazolac, lonazolac acetic acid ester and lonazolac argininate, were prepared and examined for physicochemical properties and biopharmaceutical characteristics. The prodrugs were stable in solid state and lonazolac argininate showed higher dissolution rate than lonazolacca in both artificial gastric and intestinal juices. These prodrugs have higher analgegic effect than that of lonazolac-Ca in mice, and increased anti-inflammatory activities in rats. In addition, ulcerogenic effects and acute toxicity of these prodrugs were lower than those of lonaaolac-Ca. Lonazolac acetic acid ester showed larger area under the plasma concentration-time curves (AUC) than that of lonazolac. Therefore, it was suggested that these prodrugs of lonazolac have advantages over lonzolac-Ca for not only enhanced bioavailability but also decreased ulcerogenic and toxic effects.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.10a
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• pp.776-779
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• 2010

Implementation for Gated Peak Detector CSAM (C Scanning Acoustic Microscope) based on One Chip processor is proposed in this paper. GDP (Gated Peak Detector) is implemented with VHDL tool. The proposed method leads to be available for its application and integration in all systems as well as acoustic microscope and the method is compared with the conventional methods. The technique results in efficiency in size and application.

• Bulletin of the Korean Chemical Society
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• v.16 no.7
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• pp.604-609
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• 1995

The relative dissociation constants of 4-substituted bicyclo[2,2,2]octane-1-carboxylic acids, 4-substituted quinuclidines, and 3-and 4-substituted pyridines were collected from a number of sources. In order to understand the actual substituent effects with a combination of inductive effect (σI) and resonance effect (σR) components. The DSP correlation has been employed statistically for each of the p-and m-series. The inductive effect from the m-position was 1.2 times more effective than that from the p-position and the requirement of σR+ for the best-fit led to the conclusion that pyridine system belongs to the σ+-class reactivity. Also compared with results from Yukawa-Tsuno's LArSR treatment and relevant treatment.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.147-159
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• 2018

Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-loxP system is widely used as an integral experimental tool for generating the conditional. This system has enabled researchers to investigate genes of interest in a tissue/cell (spatial control) and/or time (temporal control) specific manner. A various tissue-specific Cre-driver mouse lines have been generated to date, and new Cre lines are still being developed. This review provides a brief overview of Cre-loxP system and a few commonly used promoters for expression of tissue-specific Cre recombinase. Also, we finally introduce some available links to the Web sites that provides detailed information about Cre mouse lines including their characterization.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.160-165
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• 2018

Breast cancer remains the second leading cause of cancer death among woman, worldwide, despite advances in identifying novel targeted therapies and the development of treating strategies. Classification of clinical subtypes (ER+, PR+, HER2+, and TNBC (Triple-negative)) increases the complexity of breast cancers, which thus necessitates further investigation. Mouse models used in breast cancer research provide an essential approach to examine the mechanisms and genetic pathway in cancer progression and metastasis and to develop and evaluate clinical therapeutics. In this review, we summarize tumor transplantation models and genetically engineered mouse models (GEMMs) of breast cancer and their applications in the field of human breast cancer research and anti-cancer drug development. These models may help to improve the knowledge of underlying mechanisms and genetic pathways, as well as creating approaches for modeling clinical tumor subtypes, and developing innovative cancer therapy.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.203-210
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• 2018

Stress severely disturbs physiological and mental homeostasis which includes adult neurogenesis in hippocampus. Neurogenesis in hippocampus is a key feature to adapt to environmental changes and highly regulated by multiple cellular signaling pathways. The primary cilium is a cellular organelle, which acts as a signaling center during development and neurogenesis in adult mice. However, it is not clear how the primary cilia are involved in the process of restraint (RST) stress response. Using a mouse model, we examined the role of primary cilia in repeated and acute RST stress response. Interestingly, RST stress increased the number of ciliated cells in the adult hippocampal dentate gyrus (DG). In our RST model, cell proliferation in the DG also increased in a time-dependent manner. Moreover, the analysis of ciliated cells in the hippocampal DG with cell type markers indicated that cells that were ciliated in response to acute RST stress are neurons. Taken together, these findings suggest that RST stress response is closely associated with an increase in the number of ciliated neurons and leads to an increase in cell proliferation.