• 전기학회논문지
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• 제67권1호
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• pp.114-123
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• 2018

This paper concerns a design and learning method of softmax function neural networks based on K-means clustering. The partial discharge data Information is preliminarily processed through simulation using an Epoxy Mica Coupling sensor and an internal Phase Resolved Partial Discharge Analysis algorithm. The obtained information is processed according to the characteristics of the pattern using a Motor Insulation Monitoring System program. At this time, the processed data are total 4 types that void discharge, corona discharge, surface discharge and slot discharge. The partial discharge data with high dimensional input variables are secondarily processed by principal component analysis method and reduced with keeping the characteristics of pattern as low dimensional input variables. And therefore, the pattern classifier processing speed exhibits improved effects. In addition, in the process of extracting the partial discharge data through the MIMS program, the magnitude of amplitude is divided into the maximum value and the average value, and two pattern characteristics are set and compared and analyzed. In the first half of the proposed partial discharge pattern classifier, the input and hidden layers are classified by using the K-means clustering method and the output of the hidden layer is obtained. In the latter part, the cross entropy error function is used for parameter learning between the hidden layer and the output layer. The final output layer is output as a normalized probability value between 0 and 1 using the softmax function. The advantage of using the softmax function is that it allows access and application of multiple class problems and stochastic interpretation. First of all, there is an advantage that one output value affects the remaining output value and its accompanying learning is accelerated. Also, to solve the overfitting problem, L2-normalization is applied. To prove the superiority of the proposed pattern classifier, we compare and analyze the classification rate with conventional radial basis function neural networks.

• 한국약용작물학회지
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• 제22권1호
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• pp.46-52
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• 2014

In traditional Korean and Chinese medicine, safflower (Carthamus tinctorius L.) for the treatment of central nervous system-related symptoms such as tremor, seizure, stroke and epilepsy. We investigated the effects of safflower could influence cerebral ischemia-induced neuronal and cognitive impairments. Administration of safflower for 1 day (200 mg/kg body weight, p.o.) increased the survival of hippocampal CA1 pyramidal neurons after transient global brain ischemia. And neurological functions measured as short term memory. Post-treatment with safflower for 2 times decreased the induction/reduction - induced production of neuronal cell loss from global cerebral ischemia. Safflower markedly decreased neuronal cell death and also caused a decrease in the content of thiobarbituric acid-reacting substances (TBARS) ($55.2{\pm}9.4{\mu}mol\;mg^{-1}$) and significant improvement of activities of glutathione (GSH) ($27.2{\pm}5.0{\mu}mol\;mg^{-1}$) in hippocampus. We conclude that treatment with safflower attenuated learning and memory deficits, and neuronal cell loss induced by global cerebral ischemia. These results suggest that safflower may be a potential candidate for the treatment of vascular dementia.

• 한국임상보건과학회지
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• 제10권1호
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• pp.1543-1552
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• 2022

Purpose: It is intended to investigate the satisfaction of dental hygiene students with non-face-to-face online classes and use them as basic data for successful lecture design and operation. Methods: The data collected in this study were analyzed using the lBM SPSS Statistics 21 program. The general characteristics of the study subjects were frequency analysis, non-face-to-face online class satisfaction, and test satisfaction were frequency analysis and technical statistics. Through the independent sample T test, a t-test was conducted to find out whether there was an average difference in online class and test satisfaction according to grade. Results: The advantages of non-face-to-face online classes were that repetitive learning was possible (57.7%), the disadvantage was that there was a lack of real-time communication (74.9%), and the most efficient teaching method was a mixed form of online and face-to-face classes (64.9%). The satisfaction level of online classes was 2.69 points for 'self-directed learning habits,' which was the highest compared to the overall average of 2.55 points, and 2.09 points for 'difficulty in interaction between instructors and learners in online classes.'Non-face-to-face test satisfaction was 2.68 points for 'short test time gives fairness to test results,' higher than the overall average of 2.45 points, and 2.07 points for 'no difficulty accessing the test.'In terms of satisfaction with the non-face-to-face test according to the grade, it was found that the third grade showed a more negative attitude than the second grade in terms of sexual fairness (p<0.05). Conclusions: Through the above results, non-face-to-face online classes require various content development and some mixed classes considering the level of students, and instructors' efforts to improve the quality of classes for interaction between instructors and learners are needed.

• 동의신경정신과학회지
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• 제18권2호
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• pp.45-55
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• 2007

Objective : The purpose of this study was to investigate the protective effects of Radix Curcumae on the animal model of depression induced immobilization stress. Method : 1) Male rats were used for this experiment. The subject were divided into 4 groups(1. normal 2. saline solution administered during immobilization stress treatment 3. Radix Curcumae of l00mg/kg administered 4. Radix Curcumae of 400mg/kg administered). 2) Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone in blood were measured. Results : 1) In EPM test, stress group showed significantly increased anxiety, Radix Curcumae of 400mg/kg group showed significantly decreased anxiety. 2) In forced swimming test, Radix Curcumae of 400mg/kg group showed significantly decreased immobilization. 3) In passive avoidance test, stress group showed significantly decreased learning execution, Radix Curcumae groups showed significantly increased learning execution. 4) Stress group showed significantly increase in serum level of corticosterone, Radix Curcumae of 400mg/kg group showed significantly decreased serum level of corticosterone. Conclusion : These results suggest that Radix Curcumae is effective in the treatment of depression.

• 한국발생생물학회지:발생과생식
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• 제19권2호
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• pp.61-67
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• 2015

The immediate early gene c-fos has long been known as a molecular marker of neural activity. The neuron's activity is transformed into intracellular calcium influx through NMDA receptors and L-type voltage sensitive calcium channels. For the transcription of c-fos, neural activity should be strong enough to activate mitogen-activated protein kinase (MAPK) signaling pathway which shows low calcium sensitivity. Upon translation, the auto-inhibition by Fos protein regulates basal Fos expression. The pattern of external stimuli and the valence of the stimulus to the animal change Fos signal, thus the signal reflects learning and memory aspects. Understanding the features of multiple components regulating Fos signaling is necessary for the optimal generation and interpretation of Fos signal.

• 인지과학
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• 제11권1호
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• pp.47-65
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• 2000

정보검색 엔진이 제공하는 홈페이지의 분류체계는 사용자보다는 시스템을 고려하여 구성되기 쉽다. 본 연구는 대표적인 검색엔진들을 중심으로 분류체계에서 대분류 및 중분류에 대한 사용자들의 심성 모형을 조사하고, 이를 바탕으로 중복 분류체계와 단선 분류체계를 구성하였다. 중복 분류체계에서는 한 하위 분류 명이 여러 상위 분류에 소속될수 있으며, 단선 분류체계에서는 그렇지 않다. 심마니 분류체계를 포함시켜, 세 분류체계를 디자인한 다음 검색 문제를 제시하여 이에 대한 분류 검색 수행을 2차에 걸쳐 관찰하였다. 정답 빈도. 검색에 소요된 단계수 및 경과한 시간 등의 자료를 종합적으로 볼 때, 중복 분류체계에서의 수행이 다른 두 조건보다 좋았다. 이는 적절한 분류체계에서 분류 검색이 향상될 수 있음을 시사한다. 그러나, 분류체계에 대한 재인 검사 점수는 단선 분류체계에서 가장 좋았다. 이는 분류 검색 수행과 분류체계의 재인 기억이 분류체계의 학습에서 상이한 측면을 반영할 것임을 시사한다. 끝으로 분류의 조직화, 인터페이스 방식, 사전지식, 탐색학습 및 응용 영역에 대한 논의가 있었다.

• 한국컴퓨터산업학회논문지
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• 제5권2호
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• pp.193-202
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• 2004

본 연구는 인터넷기반 실습 수업에서 교수자와 학습자가 어떠한 방식으로 교수-학습 상호작용 활동을 수행하는 방식과 웹기반 실습 수업의 교육적 효과에 관하여 연구하였다. 산업체 재직자의 정보화교육을 지원하는 "전자상거래 시스템 구축" 교육과정에서 교수자와 학습자는 어떤 방식으로 교수-학습 및 상호작용 활동을 수행하는지, 웹기반 실습교육의 효과는 무엇인지를 살펴보고자 하였다. 연구대상은 산업체 직장인 및 기타 25인에 대하여 1학기에 걸쳐서 이루어졌으며, 연구방법으로는 학습결과 프로파일 분석, 설문조사, 인터뷰 등을 사용하였다. 연구결과 학습자-교수자-운영자간 상호작용은 활발하게 이루어지지 않았으나 학습자의 관심, 이메일 사용, 게시판 질의 및 응답, 온라인 실습 등의 강의 방식이 학습자의 상호작용 및 교육효과에 영향을 미치는 것으로 나타났다. 것으로 나타났다.

• The Korean Journal of Physiology and Pharmacology
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• 제21권6호
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• pp.579-589
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• 2017

Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic AMP response element-binding protein (CREB) are involved in learning and memory processes. Genistein, a plant-derived isoflavone, has been shown to exhibit neuroprotective effects. The present study was performed to examine the protective effect of genistein against isoflurane-induced neurotoxicity in rats. Neonatal rats were exposed to isoflurane (0.75%, 6 hours) on postnatal day 7 (P7). Separate groups of rat pups were orally administered genistein at doses of 20, 40, or 80 mg/kg body weight from P3 to P15 and then exposed to isoflurane anesthesia on P7. Neuronal apoptosis was detected by TUNEL assay and FluoroJade B staining following isoflurane exposure. Genistein significantly reduced apoptosis in the hippocampus, reduced the expression of proapoptotic factors (Bad, Bax, and cleaved caspase-3), and increased the expression of Bcl-2 and Bcl-xL. RT-PCR analysis revealed enhanced BDNF and TrkB mRNA levels. Genistein effectively upregulated cAMP levels and phosphorylation of CREB and TrkB, leading to activation of cAMP/CREB-BDNF-TrkB signaling. PI3K/Akt signaling was also significantly activated. Genistein administration improved general behavior and enhanced learning and memory in the rats. These observations suggest that genistein exerts neuroprotective effects by suppressing isoflurane-induced neuronal apoptosis and by activating cAMP/CREB-BDNF-TrkB-PI3/Akt signaling.

• 대한원격탐사학회지
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• 제33권5_1호
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• pp.455-467
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• 2017

초분광 영상을 이용한 표적 탐지를 수행할 때에는 인접한 분광 밴드의 중복성의 문제 및 고차원 데이터로 인해 발생하는 방대한 계산량의 문제점을 해결하기 위한 특징 추출 과정이 필수적이다. 본 연구는 기계 학습 분야의 특징 선택 기법을 초분광 밴드 선택에 적용하기 위해 $L_{2,1}$-norm regression 모델을 이용한 새로운 밴드 선택 기법을 제안하였으며, 제안한 밴드 선택 기법의 성능 분석을 위해 표적이 존재하는 초분광영상을 직접 촬영하고 이를 바탕으로 표적 탐지를 수행한 결과를 분석하였다. 350 nm~2500 nm 파장 대역에서 밴드 수를 164개에서 약 30~40개로 감소시켰을 때 Adaptive Cosine Estimator(ACE) 탐지 성능이 유지되거나 향상되는 결과를 보였다. 실험 결과를 통해 제안한 밴드 선택 기법이 초분광 영상에서 탐지에 효율적인 밴드를 추출해 내며, 이를 통해 성능의 감소 없이 데이터의 차원 감소를 수행할 수 있어 향후 실시간 표적 탐지 시스템의 처리 속도 향상에 도움을 줄 수 있을 것으로 보인다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.363-363
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• 2022

LID 시설에 대한 모니터링은 인력을 활용한 실강우 모니터링을 진행하고 있으나 LID 시설은 소규모 분산형시설로서 인력을 동원한 식생고사, 강우시 모니터링, 현장답사 등 꾸준한 시설확인에 한계가 있으며, LID 시설을 조성한 이후 적정한 유지관리 방법(주기, 빈도, 항목 등)을 인지하지 못하여 막힘현상, 효율저하, 식물고사 등의 문제가 발생한다. 따라서 본연구에서는 딥러닝 분석을 활용하여 강우시 강우모니터링 자료와 LID 시설 내 센서를 통해 측정된 자료를 통해 침투도랑 내 유입수 성상에 대한 예측분석을 수행하였다. 심지 내 LID 시설에 유입되는 오염물질을 예측을 위한 딥러닝 분석을 위해 과거 실강우시 모니터링 자료(TSS, COD, TN, TP)와 대기센서(대기습도, 대기온도, 강수량, 미세먼지) 데이터를 활용하여 딥러닝 모델에 대한 적용가능성 평가를 수행하였다. 측정항목에 대한 상관성 분석을 수행하였으며, 딥러닝 모델은 Tenser Flow를 이용하여 DNN(Deep Neural Network)모델을 활용하여 분석하였다. DNN 모델에 대한 MSE값은 0.31로 분석되었으며, TSS에 대한 평균 50.6mg/L로 분석되었으며, COD 평균 98.7 mg/L로 나타났다. TN의 평균 2.21 mg/L로 분석되었으며, TP 평균 0.67 mg/L로 나타났다. 상관계수분석결과 TSS는 0.53로 분석되었으며, TN과 TP의 상관계수는 0.10, 0.56으로 나타났다. COD의 상관계수는 0.63으로 TSS와 COD, TP에 대한 예측이 된 것으로 분석되었다. 딥러닝을 통한 LID 시설 내 농도변화 예측시 강우시 센서데이터 값은 조밀해야하며 오염물질 농도와 상관성이 높은 항목들에 대해 계측과 실강우 모니터링 자료를 축적하여 미래에 대한 활용성을 높여야 한다.