• Korean Journal of Clinical Laboratory Science
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• v.48 no.4
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• pp.287-295
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• 2016

This study was conducted to assess the relationship amongst serum ferritin, and metabolic syndrome (MetS) and metabolic syndrome score (MSS) in Korean adults. The data of 16,096 adults (6,840 men as well as 4,916 premenopausal and 4,340 postmenopausal women) aged ${\geq}20years$ in the Korean National Health and Nutrition Examination Survey (KNHANES) between 2010 and 2012 were analyzed. The prevalence rate of MetS was 3,978 (24.7%) (men, 24.6%; premenopausal women, 11.1%; postmenopausal women, 40.3%). The key study results were as follows: First, after the adjustment for relevant variables, the serum ferritin level ($M{\pm}SE$) was significantly higher (p<0.001) in the MetS group (men, $132.25{\pm}1.98ng/mL$; premenopausal women, $39.89{\pm}1.49ng/mL$; postmenopausal women, $73.45{\pm}1.14ng/mL$) than in the non-MetS group (men, $111.08{\pm}1.01ng/mL$; premenopausal women, $32.26{\pm}0.50ng/mL$; postmenopausal women, $63.26{\pm}0.98ng/mL$). Second, the serum ferritin levels increased as MSS increased in all groups (men, premenopausal women, and postmenopausal women) (p<0.001). In conclusion, MetS and MSS increases were positively associated with higher serum ferritin levels.

• Analytical Science and Technology
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• v.28 no.5
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• pp.309-316
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• 2015

The analytical method of lead in plasma by ICP-MS was validated after securing environment within class 1,000 classification. We tested specificity and accuracy of within-run and between-run. According to measurement of the amount of suspended particulates in a clean room, 0.3~62 particles were detected in 0.3 µm size while 0.0~28.3 particles were observed in 0.5 µm size. Total suspended particulates met required environment with up to 90.3 particles. The MDL (Method detection limit) of the sample which has been fabricated using fetal bovine serum (FBS) blank was 1.77 ng/L, and LOQ (Limit of quantification) was 5.55 ng/L. The slope, intercept and correlation coefficient of the calibration curve were y=1.09×10⁻³x+4.88×10⁻² and r=0.9999, which showed good correlation. The specificity, within-run and between-run accuracy satisfied the standard at more than 50 ng/L. The average lead concentration in plasma of the general people, current workers and retired workers was 55.4 ng/L, 440 ng/L, and 132 ng/L.

• Korean Journal of Poultry Science
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• v.32 no.4
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• pp.231-237
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• 2005

This study was carried out to evaluate the breeding values for economic traits in Korean native chicken on the basis of 11,583 birds of record along 7 generations collected from 1995 to 2001 at National Livestock Research Institute, Korea. The results obtained are summarized as follows : The breeding value estimates of the body weights at 150 and 270 days in Dark Brown, Light Brown, Gray Brown, Black and White strains were $-16.563\~0.474\;and\;-18.836\~21.700,\;-14.714\~9.272\;and\;-23.025\~11.297,\; -25.186\~12.953\;and\;-28.368\~18.156,\;-15.549\~6.329\;and\;-18.264\~4.963,\;-10.708\~20.284\; and\;-25.112\~10.132g$, respectively. The breeding value estimates of the ages at first egg in Dark Brown, Light Brown, Gray Brown, Black and White strains were $-1.236\~0.047,\;-1.509\~0.298,\;-1.362\~0.114,\;-1.436\~0.199\;and\;-1.385\~0.718$, respectively. The breeding value estimates of the egg weight at first egg and at 270 days were $-0.105\~0.075\;and\;-0.120\~0.398,\;-0.109\~0.042\;and\;-0.205\~0.173,\;-0.166\~0.084\;and\;-0.256\~0.091,\;-0.119\~0.066\;and\;-0.051\~0.132,\;-0.112\~0.027\;and\;-0.070\~0.101g$, respectively. The breeding value estimates of the egg Production to 270 days in Dark Brown, Light Brown, Gray Brown, Black and White strains were $0.298\~l.807,\;-0.049\~l.146,\;-0.396\~l.125,\;-1.206\~l.173\;and\;-0.474\~2.641$, respectively.

• Food Science and Preservation
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• v.6 no.4
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• pp.514-520
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• 1999

Changes in pH, titratable acidity, CO$_2$production, reducing sugar, and lactic acid bacteria of fresh kimchi juice supplemented with combinations of 3 lactic acid bacteria and germanium(Ge)-132 or fructooligosaccharide(FO) during fermentation at 30$^{\circ}C$ were investigated to assess the potential for extending the shelf life and enhancing the functional properties in kimchi. In kimchi juice containing Ge-132, sample(I) (inoculated with a mixture of bacteriocin-producing SNF-13 strain and E. faecium) exhibited that the amounts of organic acid and evolved CO$_2$gas were lower than those of the other starter samples(II-IV). The growth of lactic acid bacteria naturally present in kimchi juice, particularly Lb. plantarum and Leu. mesentroides, may be inhibited due to competition of the isolated SNF-13 strain and E. faecium by Ge-132. During fermentation of kimchi juice containing FO sugar, the contents of organic acid and evolved CO$_2$gas On juice broth with 4 starters were predominantly higher than those of control and Ge-132 groups, and then the growth of lactic acid bacteria originated from kimchi ingredients was thought to be markedly accelerated. Our results indicated that functional properties like the extension of shelf life and increase of biological activity in kimchi were enhanced by adding Ge-132 and bacterium-producing lactic acid bacterium, which were resistant to organic acid and stimulated by Ge-132.

• Journal of the Korean Mathematical Society
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• v.48 no.1
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• pp.117-132
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• 2011

By developing a linear algebra program involving many different structures associated to a three-graded H*-algebra, it is shown that if L is a Lie triple automorphism of an infinite-dimensional topologically simple associative H*-algebra A, then L is either an automorphism, an anti-automorphism, the negative of an automorphism or the negative of an anti-automorphism. If A is finite-dimensional, then there exists an automorphism, an anti-automorphism, the negative of an automorphism or the negative of an anti-automorphism F : A $\rightarrow$ A such that $\delta$:= F - L is a linear map from A onto its center sending commutators to zero. We also describe L in the case of having A zero annihilator.

• Journal of Microbiology and Biotechnology
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• v.18 no.11
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• pp.1858-1861
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• 2008

A PCR-enzyme-linked immunosorbent assay (PCR-ELISA) was developed for the rapid and sensitive detection of L. monocytogenes. PCR primers generating a 132-bp amplicon and a capture probe able to hybridize to the PCR amplicon were designed based on the L. monocytogenes-specific hly gene encoding listeriolysin. The detection limit of PCR-ELISA for L. monocytogenes was determined to be as low as 10 cells per PCR reaction, and this level of detection was achieved within 5 h. These results indicate that the PCR-ELISA provides a valuable tool for the rapid and sensitive detection of L. monocytogenes for the ready-to-eat food industry.

• The Korean Journal of Zoology
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• v.36 no.1
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• pp.123-132
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• 1993

곤충의 탈피작용에서 일어나는 키틴 분해대사를 구명하기 위한 목적으로 배추흰나비 (Pieris rupae L.)에서 3종의 서N-acetylglucosaminldase(El, Ell, Elll)를 분리, 정제하였다. Polvacrylamide gel 상에서 이들 효소의 활성은 기질과 triphenvltetrazolium chloride와의 반응 결과 생기는 발색정도로 확인하였다. 각각의 분자량은 76,000, 55,000, 35,000 da, pl 값은 모두 5.8이었으며 후p$\beta$GlcNAc와 각p$\beta$GaINAc에 대해서 다같이 기질특이성을 나타내었다. 또한 El과 Elll는 탈피 시기와 일치하는 전용 말기에 최대 활성을 나타내었으며 Ell는 용화 직후에 최대 활성을 나타내었다.

• Applied Chemistry for Engineering
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• v.28 no.4
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• pp.420-426
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• 2017

Recently, solvent-resistant nanofiltration membranes have been studied for the separation of solvents or solutes using a molecular weight cut-off system of the polymer which is resistant to a specific solvent. Required conditions for these membranes must have are excellent physical properties and solvent resistance. Polybenzimidazole, which is known to be one of the most heat-resistant commercially available polymers, has an excellent inherent solvent resistance and it is even insoluble in stronger organic solvents when cross-linked. Therefore, in this study, the applicability of polybenzimidazole as a solvent resistant nanofiltration membrane was discussed. The membrane was fabricated using the non-solvent induced phase separation method and showed a suitable morphology as a nanofiltration membrane confirmed by field emission scanning electron microscopy. In addition, the permeance of the solvent in the presence or absence of cross-linking was investigated and the stability was also confirmed through long operation. The permeance test was carried out with five different solvents: water, ethanol, benzene, N, N-dimethylacetamide (DMAc) and n-methyl-2-pyrrolidone (NMP); each of the initial flux was $6500L/m^2h$ (water, 2 bar), $720L/m^2h$ (DMAc, 5 bar), $185L/m^2h$ (benzene, 5 bar), $132L/m^2h$ (NMP, 5 bar), $65L/m^2h$ (ethanol, 5 bar) and the pressure between 2 and 5 bar was applied depending on the type of membrane.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.287-292
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• 1999

동해 38도 10분N, 132도 00분E(site 1)과 38도 01분N, 132도 53분E(site2)에서 저주파수를 이용한 해상실험자료를 이용하여 해저면 음파반사 특성을 파악하였다. 음원으로는 한국해양연구소 온누리호에 장착되어 있는 총 11.31l의 부피를 가지는 에어건 array를 사용하였고 수신장치로는 총 56채널로 이루어진 아날로그 스트리머를 사용하였으며, 각 실험위치에서 3번씩 신호를 수신하였다. 관측해역에 대해 eigenray 모델을 이용하여 에어건에서부터 각 채널까지의 eigenray 정보를 파악한 후 해저면 반사계수를 산출하여 Rayleigh reflection 모델과 비교하였다. 비교 결과 Rayleigh reflection 모델은 해저면 반사 손실과 부합하는 것으로 나타났다.

• Journal of Genetic Medicine
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• v.18 no.2
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• pp.132-136
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• 2021

Maturity-onset diabetes of the young (MODY) is caused by autosomal dominant pathogenic variants in one of 14 currently known monogenic genes. Characteristics of patients with MODY include early-onset clinical disease with a family history of diabetes and negative autoantibodies and may present with heterogeneous phenotypes according to the different subtypes. Here, we report a patient with early-onset diabetes who presented asymptomatic mild fasting hyperglycemia with the absence of autoantibodies. She was diagnosed with glucokinase (GCK)-MODY caused by a GCK variant, c.1289T>C (p.L430P), identified by targeted gene-panel testing, and the affected father had the same variant. We interpreted this rare missense variant as a likely pathogenic variant and then she stopped taking oral medication. This case highlights the usefulness of gene-panel testing for accurate diagnosis and appropriate management of MODY. We also note the importance of familial genetic testing and genetic counseling for the proper interpretation of MODY variants.