• Title/Summary/Keyword: L-System

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Genetic Effects of Pesticides in the Mammalian Cells: II. Mutagenesis in L5178Y Cells and DNA Repair Induction

  • Park, sang-Gi;Lee, Se-Yong
    • The Korean Journal of Zoology
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    • v.20 no.4
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    • pp.159-168
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    • 1977
  • In order to evaluate the mutagenic potentential in mammalian system for those pesticides which were proved to be mutagenic in Salmonella microsome assay system, we have studied drug-resistant mutagenesis in cultured L5178Y cells and unscheduled DNA synthesis in human lymphocytes in vitro. We have tested five pesticides: insecticides DDVP and trichlorfon, fungicide TMTD and herbicides MO and NIP. Of these pesticides, TMTD induced weak mutation to MTX-resistance in L5178Y cells in vitro and gave positive responses in DNA repair assay system. Therefore, its potential genetic risks in human beings should be re-evaluated. DDVP and trichlorfon gave negative response in L5178Y mutagenesis test system but stimulated incorporation of $^{3}H$-TdR in DNA repar assay. MO and NIP gave also negative responses both in L5178Y mutagenesis test systemand in DNA repair assay system.

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Evolutionary Neural Networks based on DNA coding and L-system (DNA Coding 및 L-system에 기반한 진화신경회로망)

  • 이기열;전호병;이동욱;심귀보
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2000.11a
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    • pp.107-110
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    • 2000
  • In this paper, we propose a method of constructing neural networks using bio-inspired emergent and evolutionary concepts. This method is algorithm that is based on the characteristics of the biological DNA and growth of plants. Here is, we propose a constructing method to make a DNA coding method for production rule of L-system. L-system is based on so-called the parallel rewriting mechanism. The DNA coding method has no limitation in expressing the production rule of L-system. Evolutionary algorithms motivated by Darwinian natural selection are population based searching methods and the high performance of which is highly dependent on the representation of solution space. In order to verify the effectiveness of our scheme, we apply it to one step ahead prediction of Mackey-Glass time series.

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Designing a Microworld for Recursive Pasterns and Algebra (재귀적 패턴과 거북 마이크로월드 설계)

  • Kim Hwa-Kyung
    • The Mathematical Education
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    • v.45 no.2 s.113
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    • pp.165-176
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    • 2006
  • In this paper, we consider changes of algebra strands around the world. And we suggest needs of designing new computer environment where we make and manipulate geometric recursive patterns. For this purpose, we first consider relations among symbols, meanings and patterns. And we also consider Logo environment and characterize algebraic features. Then we introduce L-system which is considered as action letters and subgroup of turtle group. There are needs to be improved since there exists some ambiguity between sign and action. Based on needs of improving the previous L-system, we suggest new commands in JavaMAL microworld. So we design a microworld for recursive patterns and consider meanings of letters in new environments. Finally, we consider the method to integrate L-system and other existing microworlds, such as Logo and DGS. Specially, combining Logo and DGS, we consider the movement of such tiles and folding nets by L-system commands. And we discuss possible benefits in this environment.

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Design of Communication Interface Module for Home-appliances based on Low-speed Power Line Communications (저속 전력선 통신 기반의 가전기기용 통신장치의 통신 인터페이스 모듈의 설계)

  • Lee, Kam-Rok;Lee, Jae-Min;Myoung, Kwan-Joo;Kim, Dong-Sung;Kwon, Wook-Hyun
    • Proceedings of the KIEE Conference
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    • 2002.07d
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    • pp.2556-2558
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    • 2002
  • In this paper, the design guideline of communication interrace module for home-appliances is proposed. The requirements of the interface between white-goods and communication module are analyzed. Finally, the proposed interface structure is implemented using PLC technology.

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EXPRESSION AND FUNCTIONAL CHARACTERIZATION OF AMINO ACID TRANSPORT SYSTEM L IN SAOS2 HUMAN OSTEOGENIC SARCOMA CELLS (사람 골육종 세포 Saos2에서 아미노산 수송계 L의 발현 및 기능적 특성)

  • Kim, Su-Gwan;Kim, Hyun-Ho;Kim, Chang-Hyun;Kim, Do-Kyung
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.32 no.3
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    • pp.200-208
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    • 2006
  • Amino acids are required for protein synthesis and energy sources in all living cells. The amino acid transport system L is a major nutrient transport system that is responsible for $Na^+$-independent transport of neutral amino acids including several essential amino acids. In malignant tumors, the L-type amino acid transporter 1 (LAT1), the first isoform of system L, is highly expressed to support tumor cell growth. In the present study, the expression and functional characterization of amino acid transport system L were, therefore, investigated in Saos2 human osteogenic sarcoma cells. RT-PCR and western blot analyses have revealed that the Saos2 cells expressed the LAT1 and the L-type amino acid transporter 2 (LAT2), the second isoform of system L, together with their associating protein heavy chain of 4F2 antigen (4F2hc) in the plasma membrane, but the expression of LAT2 was very weak. The uptakes of [${14}^C$]L-leucine by Saos2 cells were $Na^+$-independent and were completely inhibited by the system L selective inhibitor, 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH). The affinity of [${14}^C$]L-leucine uptake and the inhibition profiles of [${14}^C$]L-leucine uptake by various amino acids in the Saos2 cells were comparable with those for the LAT1 expressed in Xenopus oocytes. The majority of [${14}^C$]L-leucine uptake is, therefore, mediated by LAT1 in the Saos2 cells. These results suggest that the transports of neutral amino acids including several essential amino acids into Saos2 human osteogenic sarcoma cells are for the most part mediated by LAT1. Therefore, the Saos2 human osteogenic sarcoma cells are excellent tools for examine the properties of LAT1. Moreover, the specific inhibition of LAT1 in tumor cells might be a new rationale for anti-tumor therapy.

A Study on the Implementation of e-B/L for the Dissemination of Global e-Trade (글로벌 전자무역 확산을 위한 전자 선하증권 도입과 구현전략에 관한 연구)

  • Lee, Sang-Jin
    • International Commerce and Information Review
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    • v.10 no.1
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    • pp.193-214
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    • 2008
  • This study aims to examine similarities and differences of each e-B/L types as well as identify problems of e-B/L utilization and directions for improvement. Especially, it suggests strategies for the realization of e-B/L through reviewing and analyzing commercial types of e-B/L, which have been developed so far. Although e-B/L succeeded in realizing the function as a certificate of title and its distribution value, it has not been fully implemented due to operational problems. Subsequently, e-B/L was realized in the Bolero project as an attempt of system to make up for shortcomings in the failure of previous e-B/L types, but it has still a number of problems. To solve this problem and make use of e-B/L more efficiently, this study focuses on the specific ways to introduce e-B/L and suggest directions for the development of e-Nego system. Preparation of electronic documents is a prerequisite for the development of the e-Nego system, taking distribution of electronic documents into consideration. Next, compatibility of electronic documentation and paper-based documents should be realized, with the guarantee of authenticity of electronic documents.

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L-RE Coordinates Algorithm for Task Scheduling in Real-time Multiprocessor System (실시간 멀티프로세서 시스템에서의 태스크 스케줄을 위한 L-RE 좌표 알고리즘)

  • Huang, Yue;Kim, Yong-Soo
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.3
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    • pp.147-153
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    • 2007
  • Task scheduling is an essential part of any computer system for allocating tasks to a processor of the system among various competitors. As we know, in real-time system, the failure of scheduling a hard real-time task my lead to disastrous consequence. Besides efficiency, resource and speed, real-time system has to take time constraint in serious consideration. This paper proposes a priority-driven scheduling algorithm for real-time multiprocessor system. which is called L-RE coordinates algorithm. L-RE coordinates is a new way of describing the task scheduling problem. In the algorithm, we take both deadline and laxity into consideration for allocating the priority. The simulation result shows that the new algorithm is viable and performance better than EDF and LLF algorithm on schedulability and context switch respectively.

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The Characteristics of the STATCOM System operated by SVPWM (SVPWM 방식의 STATCOM 시스템 동작 특성)

  • Lee, Hwa-Su;Kim, Yong-Heon;Lee, Eun-Woong;Lee, Dong-Ju
    • Proceedings of the KIEE Conference
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    • 2003.10b
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    • pp.69-71
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    • 2003
  • STATCOM which is connected the load parallel with capacitor, is the reactive power compensation device. In this paper, we study the principle of reactive power compensation with STATCOM system. And then we confirmed the function of STATCOM system to be fabricated by our lab, being measured and analyzed the output voltage and current

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