• Journal of The Geomorphological Association of Korea
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• v.19 no.4
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• pp.123-137
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• 2012

Reddish superficial materials in southern area of Korean Peninsula have been defined as lateritic red soil in Korea. In A-CN-K ternary plots, CaO and $Na_2O$ show similar linear distribution along a A-K line to kaolinite profile and laterite in southern Spain and Cameroon, respectively, and it means strong alteration. But $K_2O$ is weak alteration, plotting between muscovite and illite zone. Granitic reddish weathering mantles in study area show bulk distribution in center when plotted in A-CNK-Fm space, in contrast to laterite in Cameroon, plotting linearly in the middle along a A-FM line. Therefore, alteration of reddish saprolites in Southern Korea have not progressed as much as laterite. To define Reddish saprolite in southern Korean Peninsula as a lateritic red soil, more many studies are necessary.

• Journal of Korean Society of Disaster and Security
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• v.14 no.4
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• pp.1-7
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• 2021

Although the working environment has changed significantly compared to the past, such as the implementation of the five-day work week and the aging of the population, it is not reflected in the current industrial accident index calculation such as frequency rate, severity rate, and safe T-score. In this study, statistical data were used to understand time-series trends such as increase in life expectancy, working age, shortening of working hours, and average age of death by accident. As a result of time series trend analysis of statistical data, life expectancy increased to 83.3 years, and the legal working age was raised to 65 years due to the aging of the population. Also, with the advent of the 5-day work week since 2001, the average annual working hours decreased to 2008.1 hours. It can be confirmed through statistical data that these phenomena are applied to the current working environment due to a complex action, and these environmental changes affect the calculation results of the industrial accident index.

• Analytical Science and Technology
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• v.31 no.2
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• pp.96-105
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• 2018

This study aimed to improve the method for detecting eight secondary aliphatic amines (SAAs), so as to measure their concentrations in fresh water and tap water samples. NaOH (8 mL, 10 M) and benzenesulfonyl chloride (2 mL) were added to a water sample (200 mL), and the mixture was stirred at $80^{\circ}C$ for 30 min. An additional NaOH solution (10 mL) was added and the stirring was continued for another 30 min. The pH of the cooled mixture was adjusted to 5.5-6.0 by adding HCl (35 %), and the SAAs were extracted using dichloromethane (50 mL). This extraction was repeated once. The extract was then washed with $NaHCO_3$ (15 mL, 0.05 M) and dried over $Na_2SO_4$ (4 g). The extract was finally concentrated to 0.1 mL, of which $1{\mu}L$ was analyzed for SAAs by GC-MS. The linearity of the spike calibration curves was high ($r^2=0.9969-0.9996$). The detection limits of the method ranged from 0.01 to $0.20{\mu}g/L$, and its repeatability and reproducibility (expressed as relative standard deviation) were both less than 10 % (6.6-9.4 %). Its accuracy (measured in percentage error) ranged between 2.4 % and 6.1 %. The established method was applied to the analysis of five surface water and 82 tap water samples. Dimethylamine was the only SAA detected in all the water samples, and its average concentration was $0.79{\mu}g/L$ (range: $0.20-2.54{\mu}g/L$). Therefore, this study improved the analytical method for SAAs in surface water and tap water, and the regional and seasonal concentration distributions were obtained.

• Korean Journal of Clinical Pharmacy
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• v.20 no.2
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• pp.107-113
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• 2010

서 론: 중환자실에서 집중적 인슐린 요법에 의한 평균혈당강하는 사망률을 감소시키는 것으로 나타났으나 이로 인한 저혈당 및 혈당변동은 새로운 문제로 대두되고 있다. 본 연구에서는 혈당과 관련한 여러 요인들이 사망에 미치는 영향을 규명하고 적정 혈당치를 확인하고자 하였다. 연구방법: 2008년 2월부터 7월 사이인 6개월 동안 서울아산병원 외과계 중환자실에서 4일 이상 재실한 18세 이상의 성인 환자를 대상으로 전자 의무기록 조사를 통해 후향적으로 연구가 진행되었다. 연구를 위해 환자의 인구학적 특성, 수술의 종류, 중환자실에서의 재실기간, 사망여부, 스테로이드 사용 유무, 기계적 인공호흡기의 사용유무, 신대체요법의 사용유무, 혈당치, 재실기간 중 스테로이드 사용유무와 인슐린 양, 입원 후 첫 24시간 동안의 포도당 주입속도, 입원 후 2일 이내와 그 이후에 발생한 균혈증 감염, APACH II와 SOFA 점수를 조사하였다. 혈당수치는 각각의 환자에서 중환자실 입실 후 가장 처음 측정된 혈당, 재실기간 중 가장 높은 혈당과 가장 낮은 혈당수치를 조사하였고 중환자실 전체 재실기간 동안 혈당수치의 평균과 변동계수를 계산하였다. 이상의 혈당관련지표를 포함한 인자들이 일차 종속변수인 사망에 어떠한 영향을 주는지를 환자를 생존군과 사망군으로 나누어 분석하였고 ROC (receiver operator characteristic) 곡선을 사용하여 혈당지표와 APACH 및 SOFA 점수의 cut-off치를 구하여 이로부터 단변량 및 다변량 분석을 시행하였다. 결 과: 연구에 포함된 환자는 170명 이었고 그 중 23명이 연구 기간 중 중환자실에서 사망하였다. 생존자에 비해 사망자의 최대혈당은 유의적으로 높았고 최소혈당치는 유의적으로 낮아 높은 변동계수를 보였다. ROC곡선으로부터 산출된 혈당치들의 cut-off 수치는 최소혈당치 70 mg/dL, 변동계수 25%, 최대혈당치 250 mg/dL, 평균혈당치 150 mg/dL이었다. 다변량분석에서 최소혈당이 70 mg/dL 보다 큰 경우가 낮은 경우에 비해 오즈비가 0.922(95% 신뢰구간 0.881-0.965)로 유의성 있게 낮았으며 변동계수가 25% 보다 높은 집단의 경우 그보다 낮은 집단에 비해 오즈비가 1.121(95% 신뢰구간 1.017-1.236)로 유의성 있게 높았다. Kaplan-Meier 생존분석 결과 최소혈당치 70 mg/dL와 변동계수 25%에 따라 생존기간에 유의성 있는 차이가 나타났다.(각각 P < 0.001, P < 0.05) 결 론: 고혈당 발생의 감소뿐 아니라 최소혈당치를 70 mg/dL 이상으로 유지하면서 변동을 최소화하는 것이 외과계 중환자실에서의 사망률감소를 위한 중요한 요인임을 알 수 있었다.

• Journal of Food Hygiene and Safety
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• v.34 no.1
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• pp.52-57
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• 2019

Method development and validation of decursin for the standardization of Angelica gigas Nakai as a functional ingredient and health food were accomplished. The quantitative determination method of decursin as a marker compound of aerial parts of Angelica gigas Nakai extract (AAGE) was optimized by HPLC analysis using a C18 column ($3{\times}150mm$, $3{\mu}m$) with 0.1% TFA in water and acetonitrile as the mobile phase at a flow rate of 0.5 mL/min and detection wavelength of 330 nm. The HPLC/PDA method was applied successfully to quantification of the marker compound in AAGE after validation of the method with linearity, accuracy, and precision. The method showed high linearity in the calibration curve at a coefficient of correlation ($R^2$) of 0.9994 and the limit of detection and limit of quantitation were $0.011{\mu}g/mL$ and $0.033{\mu}g/mL$, respectively. Relative standard deviation (RSD) values of data from intra- and inter-day precision were less than 1.10% and 1.13%, respectively. Recovery of decursin at 0.5, 1, 5 and $10{\mu}g/mL$ were 92.38 ~ 104.11%. These results suggest that the developed HPLC method is very useful for the determination of marker compound in AAGE to develop a health functional material.

• 한국지구물리탐사학회:학술대회논문집
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• 2010.10a
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• pp.67-68
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• 2010

• Proceedings of the KSRS Conference
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• 2001.03a
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• pp.128-132
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• 2001

본 연구의 수행을 위해 23개의 JERS-1 SAR 와 두 개의 ERS-2 SAR 자료를 이용하였다. 비록 ERA-2 pair로부터 생성된 인터훼로그램(interferogram)은 70일의 짧은 간격 자료임에도 불구하고 수목, 구름, 눈 등에 의한 temporal decorrelation 과 낮은 관측각에 의한 layover등에 의해 인터훼로그램의 질이 좋지 않아 분석에 이용될 수 없었다. 반면에 JERS-1 SAR(L 밴드) 자료간의 pair는 매우 긴 시간 간격에도 불구하고 비교적 높은 긴밀도를 가지고 있어, 본 연구지역과 같이 지표 변화률이 매우 느릴 것으로 예상되는 지역에서 장기간의 변화를 관측하기에는 적합하다. 우리는 altitude of ambiguities가 매우 큰 3개의 인터훼로그램과 2-pass, 3-pass DInSAR 방법을 사용하여 1992년 9월과 1998년 10월 까지 약 6년 동안의 지표변위를 관측하였다. 다양한 시간 간격(704, 1056, 1100, 1118, 1232, 2112 days) 별로의 차분 인터훼로그램(differential interferogram)의 결과와 그들간의 상호관계성를 이용하여 연구지역의 지표변위를 분석하였다. 2-pass, 3-pass, 그리고 altitude of ambiguity가 큰 인터훼로그램으로부터 관측된 결과 모두, 백두산 산체와 남서쪽에 위치하고 있는 홍두산을 중심으로 수십km에 걸쳐서 지표가 상승하고 있음을 지시한다. 계산된 지표상승률은 1년에 약 9cm 정도이다.

• Korean Journal of Soil Science and Fertilizer
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• v.40 no.3
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• pp.208-213
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• 2007

When overland flow water is small and slow, it moves down a stream slowly and we use it as available resource. However, it could not only be good for nothing but arouse an inundation if a lot of runoff pour down to stream at a torrential rain. So it is important to know how much water to flow out and be stored in soil and on land in order to predict a flood and conserve soil and water quality. We intended to develop the prediction model of runoff in upland at a torrential rain and conducted lysimeter study in soybean cultivation and bare soil with 3 slopeness, 3 slope length and 5 soil texture from 1985 to 1991. The data of rainfall and runoff were used when daily rainfall was over 80 mm, the level of torrential rain warning. Minimum rainfall occurring runoff (MROR) was dependent on surface coverage and slope length. However soil texture and slopeness had a little influence on MROR. Runoff after MROR increased in proportion to precipitation which depended on surface coverage, soil texture and slope. Runoff ratio was larger in fine texture and bare soil than coarse soil and soybean coverage. Runoff ratio was in proportion to a square root of slope angle(radian) and reduced with slope length to converge a certain value. From these basis, we developed the prediction model following as $$Runoff(mm)=a(s^{0.5}+l^b)(Rainfall(mm)-80(1-e^{-bl}))$$ where a is a coefficient relevant soil hydraulic properties, b is a surface coverage coefficient, s is a slope angle and l is a slope length. The coefficient a was 0.5 in sandy loam and 0.6 in clay, and b was 0.06 in bare soil and 0.5 in soybean cultivation.

• The Korean Journal of Nuclear Medicine
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• v.33 no.4
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• pp.381-387
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• 1999

Purpose: The International Labor Organization (ILO) has established an international standard for chest X-ray diagnosis of pneumoconiosis since 1980. However, there is a need for improved diagnosis and staging in occupational disease. We evaluated Ga-67 citrate scintigraphy quantitatively and correlated the scintigraphic findings with pulmonary function tests and chest X-ray results. Materials and Methods: Twenty-five patients underwent whole body scintigraphy with additional chest and abdomen images 48 hrs after intravenous injection of 185 MBq of Ga-67 citrate. Ten normal controls were also studied. Regions of interest (ROI) were drawn on the posterior image to measure counts from the liver and lungs (Lung/Liver Ratio). Results: L/L ratio according to the stages of chest X-ray classification were as follows; stage 0 (normal, n=10): $0.3948{\pm}0.0692$, stage 1 (n=10): $0.5763{\pm}0.1537$, stage 2 (n=11), $0.6849{\pm}0.1459$, stage 3 (n=4) $0.9913{\pm}0.0712$. There was a significant correlation between the scintigraphic L/L ratio and the X-ray stage (r=0.618, p<0.05). However, no significant correlation between L/L ratio and pulmonary function tests were observed (p>0.05). Conclusion: Quantitative Ga-67 scintigraphy can be a useful method for staging of silicosis. However, it is not a method to assess pulmonary functional impairment.

• Journal of agriculture & life science
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• v.50 no.2
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• pp.125-138
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• 2016

To assess the industrial possibility of mixed-extracts containing Hovenia dulcis Thunberg and 12 different botanical ingredients, a protective effect was confirmed in the chronic ethanol-induced the liver, brain, and blood injury in mouse. Blood glucose levels of the normal control group(NG) and ethanol administration group(EG) were respectively 119.43mg/dL and 305.25mg/dL, and the mixed-extracts administration group(100, 200mg/kg body weight + 25% ethanol 5g/kg body weight respectively; ME100 & ME200) were decreased to 272.76mg/dL and 234.60mg/dL. Blood ethanol contents were decreased in ME100 and ME200(3.85mg/dL, 3.08mg/dL) compared to EG(4.08mg/dL), and blood acetaldehyde contents were also decreased in ME(15.76mg/dL, 15.16mg/dL) compared to EG(18.72mg/dL). The contents of hepatotoxic indicators such as glutamine pyruvic transaminase(GPT) and glutamic oxaloacetic transaminase (GOT), nephrotoxic indicators such as blood urea nitrogen(BUN), and creatine(CRE), and total cholestero(TCHO), and triglyceride(TG) in mouse blood serum were significantly decreased in the ME compared to EG. The acetylcholinesterase(AChE) activity of ME(109.00% and 108.47%, respectively) in mouse brain tissues was decreased in ME compared to EG(116.10%). Finally, ME was remarkable in vivo antioxidant activities in the mouse liver and brain tissues by superoxide dismutase(SOD), oxidized glutathione(GSH)/total GSH ratio and the malondialdehyde (MDA) assay. Therefore, the mixed-extracts was considered to be effective a high value food with protective effect against chronic ethanol traetment-induced cytotoxicity in liver and brain tissues.