• Title/Summary/Keyword: Kyung-Rak

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Antioxidative and Neuroprotective Effects of Enzymatic Extracts from Leaves of Perilla frutescens var.japonica

  • Kim, Eun-Kyung;Lee, Seung-Jae;Lim, Beong-Ou;Jeon, You-Jin;Song, Min-Dong;Park, Tae-Kyu;Lee, Kwang-Ho;Kim, Bo-Kyung;Lee, Sang-Rak;Moon, Sang-Ho;Jeon, Byong-Tae;Park, Pyo-Jam
    • Food Science and Biotechnology
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    • v.17 no.2
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    • pp.279-286
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    • 2008
  • The antioxidative activity of various enzymatic extracts from leaves of Perilla frutescens var. japonica was evaluated by measuring 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl, and alkyl radical scavenging activity using an electron spin resonance (ESR) spectrometer. For this study, the leaves were enzymatically hydrolyzed by 8 carbohydrases (Dextrozyme, AMG, Promozyme, Maltogenase, Termamyl, Viscozyme, Celluclast, and BAN) and 9 proteases [Flavourzyme, Neutrase, Protamex, Alcalase, PP-trypsin (trypsin from porcine pancreas), papain, pepsin, $\alpha$-chymotrypsin, and BP-trypsin (trypsin from bovine pancreas)]. The DPPH radical scavenging activities of Promozyme and Alcalase extracts were the highest, and the $IC_{50}$ values were 77.25 and $109.66\;{\mu}g/mL$, respectively. All enzymatic extracts of the leaves scavenged hydroxyl radical, and the $IC_{50}$ values of Celluclast and pepsin extracts which were the highest activity were 243.34 and $241.86\;{\mu}g/mL$, respectively. The BAN and $\alpha$-chymotrypsin extracts showed the highest scavenging activities, and the $IC_{50}$ values were 21.13 and $33.23\;{\mu}g/mL$, respectively. The pepsin extracts from the leaves showed protective effect on $H_2O_2$-induced DNA damage. In addition, the pepsin extracts decreased cell death in PC-12 cells against $H_2O_2$-induced oxidative damage. The findings of the present study suggest that enzymatic extracts of the leaves possess antioxidative activity.

Quality Characteristics of $Teriyaki$ sauce Added with Different Sweeteners (감미료의 종류를 달리한 데리야끼소스의 품질 특성)

  • Song, Chung-Rak;Kim, Eun-Sil;Kim, Hyun-Ah;Kim, Yong-Sik;Choi, Soo-Keun
    • Culinary science and hospitality research
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    • v.18 no.2
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    • pp.197-205
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    • 2012
  • This study examined low calorie sweeteners (fractooligosaccharide, xylitol, erythritol, agave syrup, stevioside) instead of sugar for $Teriyaki$ sauce to satisfy customers' health needs. After adding sugar, stevioside, agave syrup, erythritol, xylitol, and fractooligosaccharide to $Teriyaki$ sauce, we measured moisture and viscosity. According to the results, the sauce with stevioside had a low moisture content, but its value was the highest in viscosity. The sauce with xylitol had average sweetness equal to that of sugar, but its salinity was very low. There was no significant difference in pH value. The difference in sweet taste showed that the sauce with xylitol met the requirement of sweet taste, soy sauce flavor, taste and savory taste. Therefore, xylitol was a good ingredient for $Teriyaki$ sauce.

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A study on the Discussion on Life and Death of Oriental Medicine (동양의학(東洋醫學)의 생사론(生死論) 연구(硏究))

  • Kim, In Rak;Hong, Won-Sik
    • Journal of Korean Medical classics
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    • v.3
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    • pp.1-150
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    • 1989
  • Oriental medicine thinks life and death as the following. 1. The universe seems to be a kind of organism which is divided into 3 branches, as Heaven, Earth and Man. Man is not created from nihil by the Creator. Heaven and Earth by their interaction operate to produce man. This is similiar that zygote is not created from nihil, and that sperm and ovum are transformed into zygote by their interaction. The symbolic meaning of sperm is Heaven, and that of ovum is Earth. Mind and body, as well as spirit and body, are not the real, but artificial words for the purpose of observing and expressing one man. So there is not spiritual substance as distinct from body. The expected life span of man is subjected to change, and is always becoming through life. Fate, the Creator and the world to come cannot be said to be. 2. After one's death, man is transformend into Heaven and Earth. Dying is this process of transformation. Although man comes into existence and closes one's life, the total life of the universe does not change. The criteria of determination of death is not in cell death, but in somatic death. Somatic death divided into 2 branches, one is heart-lung death, the other is brain death. For the standard of health changes ceaselessly as time goes by, aging and dying is not the process of losing health. Because of mind cannot be seperated from body, we'll feel at ease bodily and mentally in healthy dying. The completion of lifetimes is the value of healthy dying. 3. From the viewpoint of these, we must think to let a person die healthily is the right medical ethics. The way to let a person die healthily is divided into 3 branches, one is treatment, another is prevention and the other is promotion of health. We should treat and prevent death of sickness, but take care of healthy dying.

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Solitary Plasmacytoma of the Skull - A Case Report - (두개골에 발생한 고립성 형질세포종 - 증례보고 -)

  • Han, Jeong Hoon;Park, Hae Kwan;Min, Chang Ki;Cho, Jung Ki;Park, Sung Chan;Cho, Kyung Keun;Lee, Kyung Jin;Rha, Hyoung Kyun;Choi, Chang Rak;Kang, Joon Ki
    • Journal of Korean Neurosurgical Society
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    • v.29 no.5
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    • pp.701-705
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    • 2000
  • Solitary plasmacytomas are rare and account for 5-10% of all plasma cell disorders. These tumors are categorized as solitary plasmacytomas of bone(osseous) or extramedullary plasmacytomas(non-osseous). About a half of solitary plasmacytomas of bone occur in the spine but rarely in the skull. We report a case of solitary plasmacytoma of the skull presented with a painless palpable left parietal calvarial mass in an otherwise asymptomatic 38- year-old man. Skull radiographs showed a large radiolucent lesion with well defined non-sclerotic margins. Computed tomograph scan demonstrated a markedly enhancing mass extending from the epidural to the subcutaneous space. The patient underwent surgery and tumor was completely excised. Pathological examination showed tumor to be a plasmacytoma synthesizing IgG. Postoperatively, the patient received radiotherapy. There was no evidence of systemic involvement on postoperative laboratory wokups. Our recommended treatment is a complete surgical excision combined with postoperative radiation therapy. The patient should be follwed carefully for more than 10 years because of either local recurrence or possible progression to multiple myeloma.

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Characterization of the pcbD Gene Encoding 2-Hydroxy-6-Ox0-6-Phenylgexa-2,4-Dienoate Hydrolase from Pseudomonas sp. P20

  • Lim, Jong-Chul;Lee, Jeong-Rai;Lim, Jai-Yun;Min, Kyung-Rak;Kim, Chi-Kyung;Ki, Young-Soo
    • Journal of Microbiology and Biotechnology
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    • v.10 no.2
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    • pp.258-263
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    • 2000
  • 2-Hydroxy-6-oxo-6phenylhexa-2,4-dienoate (HOPDA) hydrolase catalyzes the hydrolytic cleavage of HOPDA to bemzpate and 2-hydroxypenta-2, 4-dienoate (HPD) during microbial catabolism of biphenyl and polychlorinated biphenyls. A HOPDA hydrolase gene (pcbD) was isolated from the genomic library of Pseudomonas sp. P20 and designated as pCNUO1201; a 7.5-kb XbaI DNA fragment from Pseudomonas sp. P20 was inserted into the pBluescript SK(+) XbaI site. E. coli HB101 harboring pCNU1201 exhibited HOPDA hydrolase activity. The open reading frame (ORF) corresponding to the pcbD gene consisted of 855 base pairs with an ATG initiation codon and a TGA termination codon. The ORF was preceded by a rebosome-binding sequence of 5'-TGGAGC-3' and its G+C content was 55 mol%. The pcbD gene of Pseudomonas sp. P20 was located immedeately downstream of the pcbC gene encoding 2,3- dihydroxybiphenyl 1,2-dioxygenase, and approximately 4-kb upstream of the pcbE gene encoding HPD hydratase. The pcbK gene was able to encode a polypeptide with a molecular weight of 31,732 containing 284 amino acid residues. The deduced amino acid sequence of the HOPDA hydrolase of Pseudomonas sp. P20 exhibited high identity (62%) with those of the HOPDA hydrolases of P. putida KF715, P. pseudoalcaligenes KF707, and Burkholderia cepacia LB400, and also significant homology with those of other hydrolytic enzymes including esterase, transferase, and peptidase.

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Study on the Drag Performance of the Flat Plates Treated by Antifouling Paints (방오 도료가 도장된 평판에 대한 항력 성능 연구)

  • Paik, Bu-Geun;Kim, Kyung-Youl;Cho, Seong-Rak;Ahn, Jong-Woo;Cho, Sang-Rae;Kim, Kyung-Rae;Chung, Young-Uok
    • Journal of the Society of Naval Architects of Korea
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    • v.50 no.6
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    • pp.399-406
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    • 2013
  • In the present study, the flat plate model test method is developed to evaluate the skin friction of the marine coating in the cavitation tunnel. Six-component force balance is used to measure the profile drag of the flat plate and strut. LDV(laser Doppler velocimetry) technique is also employed to evaluate the drag and to figure out the reason of the drag reduction. The flow velocities above the surface can be used to assess the skin friction, combined with direct force measurement. Since the vortical structure in the coherent turbulence structure influences on the skin friction in the high Reynolds number regime, the interaction between the turbulence structure and the surface wall is paying more attention. This sort of thing is important in the passive control of the turbulent boundary layer because the skin friction can't be determined only by wall condition. As complicated flow phenomena exist around a paint film, systematic measurement and analysis are necessary to evaluate the skin friction appropriately.

A Case of Pancreatic Acinar Cell Carcinoma (췌장 선방세포암 1예)

  • Lee, Hwa-Jung;Ji, Jun-Ho;Park, Seung-Chan;Park, Jung-Chul;Choi, Eun-Jung;Seo, Hye-Jin;Lee, Won-Sik;Lee, Jung-Lim;Bae, Byung-Jo;Shon, Kyung-Rak;Lee, Kyung-Hee
    • Journal of Yeungnam Medical Science
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    • v.25 no.2
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    • pp.128-133
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    • 2008
  • Acinar cell carcinoma is a rare tumor that represents 1~2% of all pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease. Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-old man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased $^{18}F$-fluorodeoxyglucose (FDG) uptake. Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the pancreas. The patient underwent a total gastrectomy three months later because of gastric recurrence. Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy. During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabine.

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A Case of Primary Mucinous Cystadenocarcinoma (원발성 후복막 점액낭샘암종 1예)

  • Ji, Jun-Ho;Lee, Hwa-Jung;Park, Seung-Chan;Park, Jung-Chul;Choi, Eun-Jung;Seo, Hye-Jin;Lee, Won-Sik;Lee, Jung-Lim;Bae, Byung-Jo;Shon, Kyung-Rak;Lee, Kyung-Hee
    • Journal of Yeungnam Medical Science
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    • v.25 no.2
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    • pp.134-138
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    • 2008
  • Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its pathogenesis, optimal treatment, and prognosis. A 29-year-old pregnant woman (21 weeks) presented with abdominal discomfort. CA 19-9, CA 125, and CEA were normal. Abdominal CT scanning revealed a $19{\times}15{\times}13cm$ retroperitoneal tumor. Exploratory laparotomy and tumor excision were performed. Mucinous retroperitoneal implants were removed as completely as possible. Histologically, the tumor showed focal areas of capsular invasion, but free resection margins. The uterus and both ovaries were normal in appearance. No adjuvant therapy was pursued. Six months later, peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous cystadenocarcinoma and present a review of the literature.

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Harmonic Analysis for Traction Power Supply System Using Four-Port Network Model (6단자망 회로모델을 이용한 전기철도 급전시스템의 고조파 해석)

  • Chang, Sang-Hun;O, Gwang-Hye;Kim, Ju-Rak;Kim, Jeong-Hun
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.51 no.6
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    • pp.255-261
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    • 2002
  • Recently, traction motors in trains are supplied with single phase a.c. power. After this power is converted to d.c. power, it is inverted to three phase power to operate traction motors. As going through the process of the conversion, harmonic current is generated in train. The method of conventional analysis on harmonics, studied by RTRI, is modeled with equivalent circuit of ac AT-fed electric railroad system using by the distributed constant circuit. However, this circuit as two-port network model has some difference in comparison with real system. The reason why the conventional method is different from the real system is that the conventional method dose not include three conductor groups, that is catenary, rail, and feeder, and admittance between the conductors for line capacitance. Therefore, this method has a little error. This paper proposes new method to more effectively estimate Harmonic current. In this method, numerous components in electric railway are categorized and each component is defined as a four- port network model. The equivalent circuit for the entire power supply system is also described into a four-port network model with connections of these components. In order to evaluate the efficiency and the accuracy of a proposed method, it is compared with values measured in Kyung-Bu high speed line and ones calculated by the conventional method.

Quality Comparisons of Canned Deer Meat Produce with BBQ and Jangjorim Sauce (바비큐 및 장조림 소스로 제조한 사슴고기 통조림 제품의 품질특성 비교)

  • Kim Il-Suk;Jin Sang-Keun;Hah Kyung-Hee;Park Ki-Hoon;Jung Gi-Jong;Park Seok-Tae;Kwuak Kyung-Rak;Park Jung-Kwon;Kang Yang-Su
    • Food Science of Animal Resources
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    • v.26 no.1
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    • pp.92-97
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    • 2006
  • The objective of this study was to investigate the quality characteristics of canned deer meat produce with prepared BBQ sauce (T1) and Jangjorim sauce (T2). The mixture were stuffed into cylindrical can (about 150 g each) and thermally processed at $121^{\circ}C$ for 30 min, the sample were stored at $30{\pm}1^{\circ}C$ for 60 days and analyzed with an interval of 30 days. pH, salinity, saccarinity of T1 were significantly lower (p<0.05) than that of T2. TBARS and VBN of T1 were significantly higher (p<0.05) than that of T2. In the result of sensory evaluation, all product obtained good score (p>6.0) in overall acceptability during whole storage at $30{\pm}1^{\circ}C$. Theses result should be useful in developing guidelines for canned deer meat preparation by consumer and processors.