Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Solitary Plasmacytoma of the Skull - A Case Report -

두개골에 발생한 고립성 형질세포종 - 증례보고 -

  • Han, Jeong Hoon (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Park, Hae Kwan (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Min, Chang Ki (Catholic Hemopoietic Stem Cell Transplantation Center, The Catholic University of Korea) ;
  • Cho, Jung Ki (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Park, Sung Chan (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Cho, Kyung Keun (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Lee, Kyung Jin (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Rha, Hyoung Kyun (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Choi, Chang Rak (Catholic Neuroscience Center, The Catholic University of Korea) ;
  • Kang, Joon Ki (Catholic Neuroscience Center, The Catholic University of Korea)
  • 한정훈 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 박해관 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 민창기 (가톨릭대학교 의과대학 조혈모세포이식센터) ;
  • 조정기 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 박성찬 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 조경근 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 이경진 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 나형균 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 최창락 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터) ;
  • 강준기 (가톨릭대학교 의과대학 신경외과학교실, 뇌신경센터)
  • Received : 1999.09.21
  • Accepted : 1999.11.24
  • Published : 2000.05.28
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Abstract

Solitary plasmacytomas are rare and account for 5-10% of all plasma cell disorders. These tumors are categorized as solitary plasmacytomas of bone(osseous) or extramedullary plasmacytomas(non-osseous). About a half of solitary plasmacytomas of bone occur in the spine but rarely in the skull. We report a case of solitary plasmacytoma of the skull presented with a painless palpable left parietal calvarial mass in an otherwise asymptomatic 38- year-old man. Skull radiographs showed a large radiolucent lesion with well defined non-sclerotic margins. Computed tomograph scan demonstrated a markedly enhancing mass extending from the epidural to the subcutaneous space. The patient underwent surgery and tumor was completely excised. Pathological examination showed tumor to be a plasmacytoma synthesizing IgG. Postoperatively, the patient received radiotherapy. There was no evidence of systemic involvement on postoperative laboratory wokups. Our recommended treatment is a complete surgical excision combined with postoperative radiation therapy. The patient should be follwed carefully for more than 10 years because of either local recurrence or possible progression to multiple myeloma.

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