• Proceedings of the Korea Institute of Fire Science and Engineering Conference
• /
• 2010.10a
• /
• pp.396-401
• /
• 2010

건축기술의 발달과 함께 건물은 높아지고 있지만 건물의 높이가 높아질수록 각종 재난으로부터 안전의 확보가 어려워지는 것이 현실이다. 특히 전 세계적으로 기후가 급격하게 변화하고, 재난의 유형도 다양화, 복합화 되고 있으며, 사회구조의 변화로 인해 재해로 인한 재난이 대형화되고 있는 추세이다. 특히 초고층복합빌딩은 재난이 일어나면 복합적으로 대형화된 재난이 일어날 가능성이 매우 높다. 이러한 시점에서 초고층복합빌딩에서 재난사고에 대응하기 위하여 각종 재난별로 일어날 수 있는 사고시나리오를 제시하고 앞으로 초고층복합빌딩의 재난사고에 대한 대응 방향을 제시하고자 한다.

• Bulletin of the Korean Chemical Society
• /
• v.15 no.2
• /
• pp.106-112
• /
• 1994

Six physical properties (molecular weight, heat capacity, side chain weight, side chain volume, standard entropy and partial molar volume) of amino acids, peptides and their derivatives were examined by molecular modeling techniques. The molecular connectivity index, Wiener distance index and ad hoc descriptor are employed as structural parameters to encode information about branching, size, cyclization, unsaturation, heteroatom content and polarizability. This paper examines the correlation of the molecular modeling techique's parameters and the physicochemical properties of amino acids and their derivatives. As a result, calculated values were in agreement with experimental data in the above six physical properties of amino acids, peptides and their derivatives and the molecular connectivity index was superior to the other indices in fitting the calculated data.

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.146.2-147
• /
• 2003

The benzoxathiol LYR-71 compound was discovered as an inhibitor of NF-kB transcriptional activity with an IC50 value of 5.4 uM. Furthermore, benzoxathiol LYR-71 compound inhibited the NF-kB binding activity to DNA in a dose-dependent manner, which was identified by EMSA with oligonucleotide corresponding to NF-kB consensus sequence. It is well known that NF-kB is an important transcription factor to regulate the expression of inflammatory enzymes (iNOS and COX-2) and cytokines (TNF, IL-1 and IL-6). (omitted)

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.149.2-149.2
• /
• 2003

Nitric oxide (NO) is known to work as an important signaling molecule involved in regulating a wide range of biological activities in the neuronal, vascular, and immune system. NO and its metabolites mediate a number of host defence functions and are also implicated in the pathogenesis of tissue damage associated with inflammation. Cyclohexylimminobenzoxathiol LYR-64 compound inhibited LPS-induced NO production in murine macrophages Raw264.7 with an IC50 value of 0.7 uM with 95.9% inhibition at 3 uM, 63.5% at 1 uM and 30.2% at 1 uM. (omitted)

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.151.3-152
• /
• 2003

Aromatic diamine JSH-21 showed an IC50 value of 9.2 uM with 74.5% inhibition at 30 uM, 53.5% at 10 uM and 24.5% at 3 uM on LPS-induced NO production in murine macrophages Raw 264.7. To examine whether inhibitory effect on NO production by JSH-21 was attributed to influence on iNOS expression, iNOS transcript and protein were analyzed by sequantitative RT-PCR and immunoblot analysis. Consistent with previous result on NO production, treatment of the Raw 264.7 cells with JSH-21 decreased the LPS-induced expression of iNOS transcript and protein in a dose-dependent manner with IC50 values of about 10 uM. (omitted)

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.155.1-155.1
• /
• 2003

Polyphenol QGR (quercetin 3-O-beta-(2"-galloyl)-rhamnopyranoside) was isolated from Persicaria lapathifolia (Polygonaceae). In this study, we investigated inhibitory effects of QGR and its building blocks (quercitrin, quercetin and gallic acid) on superoxide anion and NO productions in unopsonized zymosan-stimulated murine macrophages Raw264.7. QGR and quercetin showed potent inhibitory effects on unopsonized zymosan-induced superoxide anion production with IC50 values of 3.2 uM and 4.8 uM, respectively. (omitted)

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.320.2-320.2
• /
• 2002

Macrophages activated by lipopolysaccharide (LPS) are known to induce several proinflammatory proteins including COX-2. iNOS and TNF which produce chemical mediators involved in inflammatory response. Sophoricoside and its analogs (genistin, genistein and orobol) from Sophora japonica (Leguminosae) showed differential inhibitory effects on COX-1 and 2 activities. Sophoricoside and genistin shwoed IC50 values of 4 uM and 6 uM on COX-2 activity and of 1,497 uM and 135 uM on COX-1 activity, respectively. Genistein and orobol showed IC50 values of 3 uM on COX-2 activity and of 28 uM and 18 uM on COX-1 activity. respectively. Therefore. the legume isoflavonoids to be selective COX-2 inhibitors. However. sophoricoside and its analogs did not show inhibitory effects of COX-2, iNos and TNF transcripts. which were identified by the RT-PCR.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2021.05a
• /
• pp.55-58
• /
• 2021

우주 네트워크는 고지연성, 저신뢰성 등 기존의 지상 네트워크와는 차별화된 특성을 가진다. 또한 높은 예산이 투입되는 우주 임무 특성상 지상 시험 시 발견되지 않은 소프트웨어 버그가 막대한 비용을 초래할 수 있다. 그러나 현재까지 우주 네트워크 환경에 특화된 소프트웨어 업데이트 관련 연구는 부족한 실정이다. 따라서 본 연구에서는 Asynchronous Management Protocol(AMP)을 기반으로 원격 소프트웨어 업데이트 프레임워크를 새롭게 제안한다. 해당 프레임워크는 Interplanetary Overlay Network(ION) 소프트웨어를 사용하여 프로토타입을 구현하였으며, 실제 업데이트 케이스를 적용하여 기능 및 실사용성을 검증하였다.

• Journal of Applied Biological Chemistry
• /
• v.56 no.1
• /
• pp.23-27
• /
• 2013

The roots of Brassica rapa ssp. were extracted with 95% aqueous ethanol and the concentrated extracts were partitioned using ethyl acetate (EtOAc), n-butyl alcohol and $H_2O$, successively. From the EtOAc fraction, five flavonoids were isolated through repeated silica gel and octadecyl silica gel (ODS) column chromatography (c.c.). Based on NMR, mass spectrometry (MS) and IR spectroscopic data, the chemical structures of the compounds were determined to be licochalcone A (1), 4,4'-dihydroxy-3'-methoxychalcone (2), liquirtigenin (3), liquiritin (4), and isoliquiritin (5). This is the first report of these compounds isolated from the root of this plant.

• Journal of the Korean Society of Costume
• /
• v.59 no.3
• /
• pp.96-108
• /
• 2009

This study is made on the royal lady's dress In late Joseon dynasty according to the King Heon-jong and Lady Kyung-bin's Wedding Diary in the year of Jung-mi(1847) and summarised as follows: Girls' full dress was a set of a red skirt, a violet undo. jacket, and a light yellow jacket and a green Gyeon-ma-gi(a kind of top jacket) with he. hair Saeng-meo-ri hanging Do-tu-rak-daeng-gi(a kind of hair ribbon). At the big ceremony, girls wore a green Dang-ui instead of Gyeon-ma-gi. A girl picked up as a royal concubine wore a green Won-sam, which was decorated with gilt letters meaning longevity, patched emblems of gilt letter meaning longevity on the breast and on the back, belted with Bong-dae(a red sash with gilt phoenexes), like a princess's full dress. At the Kyung-bin's installation of Crown Princess and her first greeting ceremony with royal elders, she wore a green Won-sam as a formal dress, which had an embroidered emblem of phoenix, the belt with crystal ornaments, Pae-ok(佩玉), Kyu(圭) of blue jade, Shou(綬) with an phoenix. At a Dong-wrae-yun(drinking ceremony after bride and bridegroom's bowing to each other), she wore the embroidered red Jang-sam as a formal dress. Kyung-bin wore a purple Won-sam with Bong-dae as a full dress for a royal feast. According to the occasions, the same dress was differentiated with ornaments and rotors. Ji-keum-bal was an attire for ordinary ceremony. The attire was equipped with a woven gold green Dang-ui with an emblem of phoenix, a blue gilt underskirt and a red gilt overskirt. No-ui was worn as outdoor clothes. Jang-sam was worn by various classes, so it was differentiated with materials and names according to her class.