• Title/Summary/Keyword: Kv3.1

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A Study on Sparkover Discharge Characteristics of Flowing Gas (Flowing Gas의 방전특성에 관한 연구)

  • Oh, Jae-Youl;Lee, Kwang-Sik;Lee, Dong-In
    • Proceedings of the KIEE Conference
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    • 1991.07a
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    • pp.296-299
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    • 1991
  • This paper reports the characteristics of sparkover discharge in flowing gas ranging from 0[m/s] to 30[m/s] under the needle-rod gap. The important results obtained from this paper are as followers. 1. The maximum sparkover voltage of flowing gas are about 3.1[kv](d=1[cm], 5.4[kv](d=2[cm]), 8.1[kv](d=3[cm]) higher than those of static gas 2. The empirical equation obtained from this experiment is [%]$\frac{Vs}{Re}=A\;log_{10}\;Re+B$ where A=$-7.79{\times}10$ B=$5.60{\times}10^2$ 3. The duration time of sparkover decreases with increasing the Reynolds number. 4. The discharge pattern can be controlled by adjustment of the Reynolds number

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Cardiomyogenic Potential of Human Adipose Tissue and Umbilical Cord Derived-Mesenchymal Like Stem Cells (사람의 지방 및 제대에서 유래된 유사중간엽 줄기세포로부터 심근세포로의 분화 유도)

  • Park, Se-Ah;Kang, Hyeon-Mi;Kim, Eun-Su;Kim, Jin-Young;Kim, Hae-Kwon
    • Clinical and Experimental Reproductive Medicine
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    • v.34 no.4
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    • pp.239-252
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    • 2007
  • Objectives: In the present study, we examined the differentiation potential of human adipose-(HAD) and human umbilical cord-derived mesenchymal like stem cells (HUC) into cardiomyocytes. Methods: Cells were initially exposed to 5-azacytidine for 24h cells and then were cultivated in the presence or absence of activin A, TGF-$\beta$1, or Wnt inhibitor with various combinations of BMP and FGF. Assessment of cardiomyogenic differentiation was made upon the expression of cardiomyocyte-specific genes using RT-PCR. Results: HAD that cultivated in control medium for 4 weeks after 5-azacytidine expose showed new expression of TnT gene and increased expression of Cmlc1 and kv4.3 genes. However, HAD cultivated in the presence of combinations of BMP-4/FGF-4 (B4/F4) and BMP-4/FGF-8 (B4/F8) showed new expression of $\beta$-MHC gene and more increased expression of Cmlc1, TnT, TnI, Kv4.3 genes. Significantly enhanced expression of Cmlc1, TnT, and Kv4.3 genes were also observed compared to that cultivated in the control medium. Treatment of HUC with either 5-azacytidine or combinations of BMP and FGF did not affect the expression profile of these genes. However, when activin A or TGF-$\beta$1 was present in addition to the BMP-2/FGF-8 (B2/F8) after 5-azacytidine exposure, HUC exhibited new expression of $\beta$-MHC gene and increased expression of $\alpha$-CA, TnT and Kv4.3 genes. When Wnt inhibitor was present in addition to BMP and FGF, HUC showed new expression of Cmlc1 gene and increased expression of $\alpha$-CA, TnT, TnI and Kv4.3 genes. Conclusions: Based on these observations, it is suggested that HAD and HUC could differentiate into cardiomyocytes which might be used as therapeutic cells for the heart diseases.

Effect of ultrasound assisted rehydration on the quality of dried sea cucumber

  • Bambang Riyanto;Wahyu Ramadhan;Rezhelena Moesriffah
    • Fisheries and Aquatic Sciences
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    • v.26 no.9
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    • pp.535-547
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    • 2023
  • Sea cucumbers (Holothuria scabra), also known as beche-de-mer, are highly valued as a luxurious food item and have been utilized as a traditional tonic food in various Asian countries for centuries. The body walls of sea cucumbers are the main edible part, which are primarily composed of glycosaminoglycan (GAG). The rehydration of dried sea cucumber is a crucial step prior to further processing. The aim of this study was to assess the impact of ultrasound-assisted rehydration (UAR) on the quality of dried sea cucumbers. The experiment used four different rehydration methods, including conventional methods at 27℃ (KV27℃) and 15℃ (KV15℃), as well as a combination of ultrasound at 27℃ with conventional at 15℃ (UAR27 + KV15℃) and ultrasound at 15℃ with conventional at 15℃ (UAR15 + KV15℃). Results indicated that the rehydration rate (RR) was significantly affected by both the rehydration method and the temperature used (p < 0.05). UAR27 + KV15℃ was identified as the most effective method in terms of rehydration behavior and quality characteristics of dried sea cucumber, with a RR of 0.58 ± 0.53 gH2O/hour and reduced rehydration time of up to 28 hours. Moreover, the UAR27 + KV15℃ method demonstrated superior rehydration potential, nutritional value (proximate composition and sulfate content), color, lower energy, and microstructure properties compared to the other methods. The sulfate content and yield of sulfated GAGs were determined to be 89.4 mg/g and 52.8 ㎍/g, respectively. Confirmation of the absorption band of the sulfate group showed the presence of 3-N-acetyl galactosamine at a wavelength of 1,269 cm-1 and C-O-S at 860 cm-1. The sea cucumbers treated with UAR exhibited a GAG content approximately 2.9 times higher than those rehydrated with the conventional method. Eventually, the combination of UAR at 27℃ with conventional at 15℃ methods can significantly accelerate the rehydration of sea cucumber without negatively affecting its physical quality properties.

Effects of KV Pharmacopuncture on MIA-induced Osteoarthritis Rat (KV 약침이 MIA로 관절염을 유도한 랫드에 미치는 효과)

  • Park, Byung Jun;Choi, Hak Joo;Sim, Boo Yong;Yun, Mi Young;Yoo, Ji Hyun;Kim, Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.1
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    • pp.46-51
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    • 2017
  • The aim of this study is to investigate anti-arthritis activity using a KV pharmacopuncture. KV pharmacopuncture was inserted at BL40 for 4 weeks to SD-Rat, where arthritis was induced by monosodium iodoacetate (MIA) at 60 mg/ml. MMP-9, CTX II, LTB4, calcitonin and glycosaminoglycan level in serum were measured by ELISA. The cartilage of patella volume was examined and 3-D high-resolution reconstructions of the cartilage of patella were obtained using a Micro-CT system. Also, The histopathological change of knee was observed by H&E and safranin-O staining. Production of MMP-9, CTX II and LTB4 level in serum was decreased, respectively, in comparison with control. The other way, production of calcitonin and glycosaminoglycan level in serum was increased, respectively, in comparison with control. The cartilage of patella volume increased significantly. In addition, the KV group showed a increase in the cartilage volume and proteoglycan. These results may be used a remedy for new korea medicine to ease the symptoms mentioned above.

중부전력 북풍전변전소납입 275KV 450MVA 부하시 TAP 절환변압기

  • 등본광소;고추륭사;정천도부
    • 전기의세계
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    • v.28 no.2
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    • pp.14-22
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    • 1979
  • 전력계통의 증대에 따라 변전소용 변압기도 대용량화되어 가고 있다. 변전소용 대용량 변압기의 경우 최대문제가 되는 것은 철도운송의 경우 운송한계에 있다. 일본의 철도는 협궤이기 때문에 운송능력이 작고 275KV 변압기의 경우 조립운송할 수 있는 한계용량은 종래 300MVA라고 되어 왔지만, 최근 기술의 진보와 신뢰성 향상 시책에 따라 450MVA까지도 철도운송을 하는 것이 가능케 되었다. 이와같은 사정때문에 당사는 이번에 중부 전력.북풍전변전소에 3상 60Hz, 275/15 4/31.5KV, 450/450/135MVA 변압기를 납품하였다. 본기는 초고압 변전소용으로는 일본에서 최대급의 것으로 여러가지의 특징을 가지고 있다. 그 주요점을 들면, (1) 철도에 의한 조립운송을 가능케 했다. 더우기 부하시 TAP 절환기를 본체 TANK에 조립해서 운통한다. (2) 일차 초고압 권선에는 선로단을 중앙에 배치한 HISERCAP 권선을 채용한다. (3) 당초 65Phon, 장래 55Phon의 저소음사양을 만족시키기 위해서 고효율의 송유풍냉식 저소음방열관을 사용했다. (4) 기기의 신뢰성을 높이기 위해 설계, 제조, 시험 검사 각면에 만전을 기했다. 그러나 그외에도 여러가지 연구가 추진되고 있으며 다음에 개요를 설명하고져 한다.

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A Study on Measurement for Earth Resistance of Steel Structure (철탑접지저항 측정에 관한 연구)

  • 박석탁;김시영
    • 전기의세계
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    • v.22 no.6
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    • pp.33-51
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    • 1973
  • To lower the earth resistance shall be one of the most effective method for the prevention of lightening damage on power transmission line. In this report, in order to investigate various characteristic necessary to lowering the earth resistance, the following experiments have been made at 154KV U1San-PoHang T/L, 154KV YoSu-SoonChun T/L and so on. 1. Measurement of Earth specific resistance, 2. Efficiency of Earthing of concrete foundation for steel structure., 3. Efficiency of Earthing with counter poise., 4. Compound impulse test with foundation of steel structure and counter poise. With the above investigate a guidance have been prepared for the effective work-performance of steel structure.

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2DEG Transport Analysis in AlGaAs/GaAs Interface by MONTE-CARLO Method (MONTE-CARLO 방법에 의한 AlGaAs/GaAs 계면의 전자 전달특성 분석)

  • Nam, Seung-Hun;Jung, Hak-Ki;Kim, Bong-Ryul
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.2
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    • pp.94-101
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    • 1989
  • Transport properties of 2DEG at AlGaAs/GaAs interface such as average electron energy, flight distance, each valley occupancy ratio, average electron velocity for various fields are investigated by MONTE-CARLO method. As the electric field increases, more electrons transit drastically from (000) valley to (000) upper valley. This phenomenon shows the nonstationary effect such as velocity overshoot. The duration of the transient decreases from about 1.4 psec for electric field E = 7KV/cm to about 0.7 psec for 12KV/cm. The average electron velocity during transient transport in 2DEG is about 8 times the steady-state velocity for E = 12KV/cm at room temperature. In comparison with bulk GaAs the peak velocity in the 2DEG is higher than that in even pure bulk GaAs at electric field E = 7 KV/cm. On the basis of the fact that the electrons in the 2DEG have larger peak velocity and shorter transient time of velocity than those in the bulk GaAs, it is suggested that the device with 2DEG may obtain higher mobility than that with bulk GaAs.

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A Study on PAE of Tube Voltage of Diagnostic X-ray Units -At the area of Sungnam, Inchon, Seoul- (진단용(診斷用) X선장치(線裝置)의 관전압(管電壓) 백분율(百分率) 평균오차(平均誤差)에 관한 조사(調査) 연구(硏究))

  • Lim, Han-Young;Oh, Hyun-Joo;Kim, Young-Il
    • Journal of radiological science and technology
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    • v.16 no.2
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    • pp.45-50
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    • 1993
  • In this paper, the PAE of tube voltage of 93 diagnostic X-ray units those are using at the 19 general hospitals and 9 local clinics in the area of Sungnam, Inchun, and Seoul have been surveyed. The results are summarized as following. 1. PAE of tube Voltage 70, 100KV at the 56 (60%) X-ray units were ${\pm}7%$ below, at the 8 units (9%), were ${\pm}7%$ above, and those 29 X-ray units (31%) were ${\pm}7%$ below or above with the 70, 100KV tube Voltage in a unit. 2. PAE ${\pm}7%$ below were 68 X-ray units, at the low tube voltage (70KV), and 76 X-ray units at the high tube Voltage (100KV). 3. For six year-use abofe, used X-ray units were PAE ${\pm}7%$ above, and so, the longer used years the more X-ray units became declined in those performance. 4. PAE of tube Voltage were better efficiency at the large capacity 30 X-ray units than small capacity 10. 5. PAE ${\pm}7%$ abovein were only 8 units among 84 diagnostic X-ray units in the general hospitals.

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Decreased inward rectifier and voltage-gated K+ currents of the right septal coronary artery smooth muscle cells in pulmonary arterial hypertensive rats

  • Kim, Sung Eun;Yin, Ming Zhe;Kim, Hae Jin;Vorn, Rany;Yoo, Hae Young;Kim, Sung Joon
    • The Korean Journal of Physiology and Pharmacology
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    • v.24 no.1
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    • pp.111-119
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    • 2020
  • In vascular smooth muscle, K+ channels, such as voltage-gated K+ channels (Kv), inward-rectifier K+ channels (Kir), and big-conductance Ca2+-activated K+ channels (BKCa), establish a hyperpolarized membrane potential and counterbalance the depolarizing vasoactive stimuli. Additionally, Kir mediates endothelium-dependent hyperpolarization and the active hyperemia response in various vessels, including the coronary artery. Pulmonary arterial hypertension (PAH) induces right ventricular hypertrophy (RVH), thereby elevating the risk of ischemia and right heart failure. Here, using the whole-cell patch-clamp technique, we compared Kv and Kir current densities (IKv and IKir) in the left (LCSMCs), right (RCSMCs), and septal branches of coronary smooth muscle cells (SCSMCs) from control and monocrotaline (MCT)-induced PAH rats exhibiting RVH. In control rats, (1) IKv was larger in RCSMCs than that in SCSMCs and LCSMCs, (2) IKv inactivation occurred at more negative voltages in SCSMCs than those in RCSMCs and LCSMCs, (3) IKir was smaller in SCSMCs than that in RCSMCs and LCSMCs, and (4) IBKCa did not differ between branches. Moreover, in PAH rats, IKir and IKv decreased in SCSMCs, but not in RCSMCs or LCSMCs, and IBKCa did not change in any of the branches. These results demonstrated that SCSMC-specific decreases in IKv and IKir occur in an MCT-induced PAH model, thereby offering insights into the potential pathophysiological implications of coronary blood flow regulation in right heart disease. Furthermore, the relatively smaller IKir in SCSMCs suggested a less effective vasodilatory response in the septal region to the moderate increase in extracellular K+ concentration under increased activity of the myocardium.

초고압계통의 보호계전방식

  • 신대승
    • 전기의세계
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    • v.25 no.1
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    • pp.45-48
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    • 1976
  • 전력수요의 증대에 따라 송전전압이 점차 높아지는 것은 세계적 경향이며 우리 계통도 전력수요의 계속적 성장과 발전기단위용량의 대형화로 지역간 격통전력은 증가추세에 있어서 현재 154KV보다 높은 345KV대용량 송전전압을 채택하게 되었다. 이 345KV계통은 전력계통의 골격을 이루고 있으므로 공급신뢰도가 높아야겠으며 만일 고장이 발생하였을 때 고장제법의 지연이나 실패를 할 경우, 그 영향이 전계통에 파급하여 대정전을 야기할 가능성이 높으므로 계통구성의 강화와 더불어 보호계전장치도 종래보다 한층 높은 성능과 동작신뢰도를 확보해야 한다. 또 345KV변전소는 3/2CB모선이나 다단권변압기등 종래의 계통에는 없는 새로운 설비와 회로구성을 채용하기 때문에 보호계전방식도 이들과 조화된 방식으로 해야 한다.

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