• 생약학회지
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• 제50권3호
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• pp.155-158
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• 2019

Cornus alba (CA) geographically distributes in Korea, Japan, Northeast China and Russia. The cornus species have been used traditionally as anti-inflammatory, hemostatic and diuretic in Korea. Previously, it was reported CA and its separated components have excellent antioxidant, anti-inflammatory and anti-prostate cancer efficacy. Present work, the validation and content determination was tried on the ellagitannin, cornusiin B which were isolated from the CA by using high-performance liquid chromatography (HPLC). As a result, the content of cornusiin B were 3.07% in ethanolic extract of CA.

• 한국보육지원학회지
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• 제19권1호
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• pp.43-67
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• 2023

Objective: This study aimed to validate a scale which could measure the correct mediation behavior of parents for their children's smart media use. Methods: The subjects were comprised of 514 parents of 5-year-old children. The collected data were analyzed using Jasp. Results: First, in the primary validation process, a total of 19 items and five factors were extracted through exploratory factor analysis. Through secondary validation process, we found that the scale model satisfies the goodness-of-fit evaluation criteria and is valid through confirmatory factor analysis. The newly constructed parents smart media mediation scale in early childhood emerged as a valid and reliable scale. Second, it was found that the more parents pursue 'active mediation', 'instructive mediation', and 'supervision', and avoid 'co-viewing', and 'technical restrictions', the more they had a positive effect on children's smart media usage capabilities. Third, the total score of smart media mediation for young children's parents was found to significantly differentiate young children's smart media overdependence, and self-regulation. Conclusion/Implications: The final smart media mediation scale for young children's parents was composed of 19 items, with five factors: 'co-viewing', 'instructive mediation', 'technical restrictions', 'active mediation', and 'supervision'.

• 아동학회지
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• 제29권4호
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• pp.249-268
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• 2008

The Korean version of the Multidimensional Students' Life Satisfaction Scale for children(K-MSLSS) assesses children's subjective perceptions of Life Satisfaction(LS) in five conceptually relevant domains : Friends, School, Family, Living Environment, and Self. The purpose of the present study was to validate the five-factor structure of the K-MSLSS using Confirmatory Factor Analysis(CFA) procedures by means of the AMOS 7.0 statistical program. Of the 681 children(10.5 years, SD=1.1) recruited from three public elementary schools in Seoul 431 children were the calibration sample and 430 children were the validation sample. Results of the analyses found that the five-factor structure of K-MSLSS is applicable for use with Korean children from 9-12 years of age regardless of gender.

• 대한원격탐사학회지
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• 제16권4호
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• pp.315-325
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• 2000

Observations were made to validate ocean color algorithms in the Ulleung Basin, East Sea in May 2000. Small scale and meso-scale surveys were conducted for the validation of ocean color products (nLw: normalized water-leaving radiance and chlorophyll concentration). There were discrepancies between SeaWiFS and in situ nLw showing the current aerosol models of standard SeaWiFS processing software are less than adequate (Gordon and Wang, 1994). Applying the standard SeaWiFS in-water algorithm resulted in an overestimation of chlorophyll concentration. This is because that CDOM absorption was higher than the estimated chlorophyll absorption. TSS concentration was also high. Therefore, the study region deviated from Case 1 waters. The source of these materials seems to be the entrainment of coastal water by the Tsushima Warm Current. Study of the bio-optical properties in other season is desirable.

• 대한약침학회지
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• 제12권4호
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• pp.33-50
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• 2009

Objectives : This study was conducted to confirm validation and stability of concentration analysis method of pure melittin (Sweet Bee Venom-Sweet BV) extracted from the bee venom by utilizing protein isolation method of gel filtration. Methods : All experiments were conducted at Biotoxtech, a non-clinical studies authorized institution, under the regulations of Good Laboratory Practice (GLP). Standard solutions of melittin (SIGMA, USA) and test substances were dispensed and were analyzed with HPLC for Sweet BV to secure the validation of analysis. Results : 1. Measurement of system suitability of Sweet BV satisfied criterion of below 3%. 2. Confirming Linearity of Sweet BV in 10-200${\mu}g/m\ell$ solution yielded correlation coefficient (r) of 0.995 and accuracy of 85-115% which satisfy criterion. 3. Measurement of Specificity of Sweet BV didn't yield any substance affecting the peak of test substances, but detected at 21.22min verified as the test substance. 4. Confirming Intra-day of Sweet BV, accuracy and precision of 0.1, 100${\mu}g/m\ell$ were 105.70, 95.81 and 0.66, 0.73, respectively, satisfying both criteria of accuracy (85-115%) and precision (within 10%). 5. To measure Stability in autosampler, all samples used in Intra-day reproducibility sat in the autosampler for five hours and were re-analyzed. Both variability and precision satisfied the criteria. 6. Homogeneity of Sweet BV (0.1, 100${\mu}g/m\ell$) at upper, middle, and lower layers all satisfied the accuracy and precision criteria. 7. Stability of Sweet BV (0.1, 100${\mu}g/m\ell$) at room temperature for four hours and refrigerated for 7 days all satisfied the criterion. 8. For the measurement of Quality control, QC samples measured on the first and eighth day all satisfied accuracy and precision criteria. Conclusion : Above experiment data satisfies validation and stability of concentration analysis method of Sweet BV.

• Ocean and Polar Research
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• 제30권1호
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• pp.47-58
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• 2008

Several validation studies have been made for QuikSCAT(QSCAT) wind data around the world, mainly in the offshore. However, until now, there were no validation studies for QSCAT wind with resolution of 12.5 km ('QSCAT 12.5 km wind') in the vicinity of Korean Peninsula. To validate 'QSCAT 12.5 km wind' and to investigate its characteristics around Korean Peninsula, the wind data from Ieodo Ocean Research Station, KMA buoys, and KORDI Realtime Observation Stations have been compared. Validation results showed that 'QSCAT 12.5 km wind' RMSE of wind direction and speed were $25.85^{\circ}$ and 1.83 m/s, respectively, at Ieodo Station. The mean wind speed correlation coefficient of KMA buoys and KORDI Realtime Observation Station were 0.78 and 0.61, and the mean wind speed RMSE were 2.2 m/s and 3.2 m/s, respectively. This seems to be mainly because of the distance between QSCAT and in-situ observation stations. The RMSE of wind direction were bigger than $40^{\circ}$ at all in-situ observation stations located near the shore, within 20 km from coastlines. Geophysical features where in-situ observation stations are located seem to affect wind validation scores.

• 대한간호학회지
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• 제43권6호
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• pp.697-703
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• 2013

Purpose: This integrative review study was done to analyze methods used for validation studies in Korean nursing research. Methods: In this study, the literature on instrument development in nursing research from Research Information Sharing Service (RISS) and major nursing journal databases in Korea were examined. The MeSH search terms included 'nursing', 'instrument', 'instrument development', 'validation' and 189 articles were included in the review. Results: The most frequently reported validity type was content validity, followed by construct validity, and criterion validity. One third reported a single type of validity, and 15% of the studies demonstrated three kinds of validity at the same time. In about 40% of the studies, both content and construct validity were examined. Conclusion: The results of the study indicate that it is necessary to provide a wider variety of evidence to establish whether instruments are valid enough to use in nursing research.

• 대한교통학회지
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• 제25권4호
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• pp.21-32
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• 2007

가구통행실태조사를 통한 O/D 조사는 조사대상인 모집단의 규모가 대규모이므로 현실적으로 전수 조사는 가능하지 않아 일부 표본 자료에 국한하여 조사가 이루어지고 있다. 따라서 표본 자료를 전수화하여 모집단의 통행 O/D패턴을 추정할 수밖에 없다. 따라서 표본조사와 전수화 과정에서 발생할 수 있는 오차를 가능한 최소화하기 위해서 관측 교통량과 전수화 자료를 비교 검증하고 수정하는 과정이 절대적으로 필요하다. 이 논문에서는 다수의 스크린라인 선상의 관측 교통량과 표본조사자료를 기반으로 추정된 전수화 O/D 통행을 비교 검증하고 수정하는 방법을 제안하였다. 그리고 스크린라인으로 검증이 되지 않는 O/D 쌍에 대해서는 노선배정분석 결과와 관측 링크 교통량을 비교하여 수정하는 방안도 제안하였다. 그리고 우리나라 2004년도 전국 O/D 통행 자료를 활용한 사례연구 분석을 수행하였다.

• 한국농공학회논문집
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• 제66권1호
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• pp.1-13
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• 2024

This study assessed the efficacy of improving the accuracy of reservoir water level prediction models by employing automated machine learning models and efficient cross-validation methods for time-series data. Considering the inherent complexity and non-linearity of time-series data related to reservoir water levels, we proposed an optimized approach for model selection and training. The performance of twelve models was evaluated for the Obong Reservoir in Gangneung, Gangwon Province, using the TPOT (Tree-based Pipeline Optimization Tool) and four cross-validation methods, which led to the determination of the optimal pipeline model. The pipeline model consisting of Extra Tree, Stacking Ridge Regression, and Simple Ridge Regression showed outstanding predictive performance for both training and test data, with an R² (Coefficient of determination) and NSE (Nash-Sutcliffe Efficiency) exceeding 0.93. On the other hand, for predictions of water levels 12 hours later, the pipeline model selected through time-series split cross-validation accurately captured the change pattern of time-series water level data during the test period, with an NSE exceeding 0.99. The methodology proposed in this study is expected to greatly contribute to the efficient generation of reservoir water level predictions in regions with high rainfall variability.

• 한국응용과학기술학회지
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• 제41권2호
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• pp.172-187
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• 2024

비임상시험관리기준에서 독성시험 전 분석법 밸리데이션은 농도 설정 및 시료 제조 측면에서 중요하다. 시험기관에서는 의뢰받은 시험물질 2종에 대한 밸리데이션을 고성능액체크로마토그래피를 이용하여 수행한 결과 특이성, 시스템 적합성, 직선성, 일내 재현성, 균질성, 안정성, 농도분석, 품질관리를 판정 기준에 만족하는 분석방법을 확립 및 검증하였다. 하지만 의뢰기관의 시험성적서상 표준물질 함량은 시험기관의 결과보다 1.34배, 1.17배 높은 결과로 나타나 비임상시험관리기준에 적합한 분석법 밸리데이션을 통한 결과 도출이 신뢰성과 안정성 확보 측면에서 중요함을 확인하였다.