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Validation and Content Analysis of Cornusiin B Isolated from Cornus alba  

Park, Dong Hui (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
YIN, JUN (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Wang, Hye Soo (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Kim, Min (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Kim, Min Ji (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Lee, Eun kyeng (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Lee, Min Won (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
Publication Information
Korean Journal of Pharmacognosy / v.50, no.3, 2019 , pp. 155-158 More about this Journal
Abstract
Cornus alba (CA) geographically distributes in Korea, Japan, Northeast China and Russia. The cornus species have been used traditionally as anti-inflammatory, hemostatic and diuretic in Korea. Previously, it was reported CA and its separated components have excellent antioxidant, anti-inflammatory and anti-prostate cancer efficacy. Present work, the validation and content determination was tried on the ellagitannin, cornusiin B which were isolated from the CA by using high-performance liquid chromatography (HPLC). As a result, the content of cornusiin B were 3.07% in ethanolic extract of CA.
Keywords
Validation; Content; Cornus alba; Cornusiin B; HPLC;
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1 김태정 (2008) 한국의 야생화와 자원식물, P505. 서울대학교출판부, 서울.
2 Park, K. H., Yin, J., Yoon, K. H., Hwang, Y. J. and Lee, M. W. (2016) Anti-proliferative effects of hydrolysable tannins from Cornus alba in prostate cancer cells. Molecules 21: 137-148.   DOI
3 Bjoroy, O., Fossen, T. and Andersen, O. M. (2007) Anthocyanin 3-galactosides from Cornus alba “Sibirica” with glucosidation of the B-ring. Phytochemistry 68: 640-645.   DOI
4 Salminen, J., Roslin, T., Karonen, M., Sinkkonen, J., Pihlaja, K. and Pulkkinen, P. (2004) Seasonal variation in the content of hydrolyzable tannins, flavonoid glycosides, and proanthocyanidins in oak leaves. J. Chem. Ecol. 30: 1693-1711.   DOI
5 Barry, K., Davies, N. and Mohammed, C. (2001) Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography-electrospray ionisation mass spectrometry. Phytochem. Anal. 12: 120-127.   DOI
6 Fecka, I. (2009) Qualitative and quantitative determination of hydrolysable tannins and other polyphenols in herbal products from meadowsweet and dog rose. Phytochem. Anal. 20: 177-190.   DOI
7 박관희 (2013) 흰말채나무 hydrolysable tannin 의 전립선 암세포 증식 억제 활성, 석사학위논문, 중앙대학교.