• 한방안이비인후피부과학회지
• /
• 제28권3호
• /
• pp.114-125
• /
• 2015

Objectives : The objective of this study was to evaluate the effect of Herbal medicine, extrusion and Hwangryunhaedok-tang Pharmacopuncture therapy for treating Sil-Yol(Excess heat) type acne.Methods : Total of 22 patients with Sil-Yol(Excess heat) type acne were treated with the Herbal medicine(Chungsangbangpoong-tang, Yangkyuksanwha-tang, Hwalhyeolsano-tang, Galgeunhaegi-tang, Daeshihotang) and weekly Hwangryunhaedok-tang Pharmacopuncture & extrusion therpay. By the standardized photography before and after treatment, KASG and survey for patient`s satisfaction, we checked effect of Herbal medicine and Hwangryunhaedok-tang Pharmacopuncture therapy for treating acne.Results : 1. In 22 patients who underwent the Herbal medicine, extrusion and Hwangryunhaedok-tang Pharmacopuncture therapy, there was an significant improvement in KASG. Mean value of KAGS before treatment is 3.59±0.80, mean value of KAGS after treatment is 1.95±65.2. The responses to the survey for satisfaction revealed that 5 patients were very satisfied with their outcomes, 11 patients were satisfied, 5 patients were somewhat satisfied, 1 patient was dissatisfied.Conclusion : In Korean medicine, Herbal medicine and Hwangryunhaedok-tang Pharmacopuncture therpay might be effective method for treating Sil-Yol(Excess heat) type acne.

• 한방안이비인후피부과학회지
• /
• 제28권3호
• /
• pp.161-172
• /
• 2015

Objective: The purpose of this study is to report the effectiveness of Sihochunggan-tang gagambang in the four patients with eczema ongroin, inner thigh.Methods: This case study was conducted for four groin, inner thigh eczema patients who have visited Korean Medicine Clinic. Sihochunggan-tang gagambang was prescribed to all four patients and evaluated the symptom change through photographs and two assessment methods. The assessment methods are Atopic Dermatitis Severity Index(ADSI) and Visual Analogue Scale(VAS). ADSI was used to evaluate the objective symptom change and VAS was used to evaluate the subjective symptom change.Results & Conclusion: The ADSI and VAS were decreased compared to the first in all four patients in our study. And most symptoms of four patients were improved. As a result of examining ADSI, VAS scores and photographs, Sihochunggan-tang gagambang can be effective on the groin, inner thigh eczema in four cases in our study.

• 한방안이비인후피부과학회지
• /
• 제30권2호
• /
• pp.155-164
• /
• 2017

Objectives : The purpose of this study is to report the effect and safety of Eunkyo-San on pityriasis rosea in children and to suggest antiviral effect of Eunkyo-san. Methods : We performed a retrospective chart review of three cases of pityriasis rosea in children younger than 10 years who treated with Eunkyo-san. Results : One patient recovered after taking Eunkyo-san 10 times for 10 days. The others recovered after taking Eunkyo-san 30 times for 22 days and hyperpigmentation was observed in one of them. Conclusions : It is expected that Eunkyo-san is thought to be effective and safe methods for the treatment of pityriasis rosea in children. Based on existing research, it is thought that Eunkyo-san has antiviral effect through the activation of immunological mechanism, and thus Eunkyo-san appears to have a therapeutic effect on pityriasis rosea.

• 한방안이비인후피부과학회지
• /
• 제36권3호
• /
• pp.42-73
• /
• 2023

Objectives : In order to investigate the current status of recent clinical evidence related to complementary and alternative medicine(CAM) treatment for burns and to inform research and treatment strategies for future, we publish a scoping review(ScR) of randomized controlled trials(RCTs). Methods : The research question of the ScR was "Are there any RCTs of CAM treatment for burn?". RCTs published from 2000 to 2022 were identified in 7 databases(PubMed, Cochrane, CNKI, OASIS, RISS, KCI, KMbase) in March 2023. Data were tabulated and analyzed descriptively with respect to the research questions. Results : 41 RCTs were included. 21(51.2%) were conducted in China, 13(31.7%) in Iran. The main treatment criteria were herbal medicine in 28 cases, acupuncture in 9 cases, chuna therapy in 4 cases, and psychotherapy in 3 cases. Among the herbal medicine, there were 19 topical medications, 5 injections(intravenous pharmacopuncture), 4 aerosol drugs(aromatherapy), and 1 oral drug. Among the acupuncture, there were 4 plum blossom needles(seven-star needles), 2 wrist-ankle acupunctures, 2 press needles, and 1 electroacupuncture. CAM treatments were effective in treating burns. It reduced pain and pruritus at the burn site, helped recovery and management of the donor site, reduced anxiety and pain during dressing change, improved hematological problems and vital signs, and finally lowered the mortality rate. CAM treatments also lowered health care costs. Conclusions : CAM treatments for burns is prospective, and that it deserves to make high-quality studies including additional large-scale RCTs.

• 한방안이비인후피부과학회지
• /
• 제25권1호
• /
• pp.75-83
• /
• 2012

Objectives : The purpose of this study is to research the effect of bloodletting therapy and Alunitum-spread at palatine tonsil in acute tonsillitis. Methods : We reviewed medical records of 61 young patients of acute tonsillitis who had taken bloodletting therapy and Alunitum-spread from May 2003 to March 2011 in Samsung oriental medicine clinic. Results : There were 39 boys and 22 girls. Between 5 and 6 years-old group was more than the others. Between 3 and 4 days group was the first in duration of disease. Winter was the first and then spring, fall and summer in distribution of season. Between 9 and 10 days group was 22 patients, which was the first in duration of treatment. it was the first to have no history of acute tonsilitis group, and then cold, allergic rhinitis, laryngopharyngitis, acute tonsillitis and tympanitis. There were 41 patients who came to Samsung oriental medicine clinic the first and then western clinic, home remedy and other oriental clinic. Sore throat was the first sympton and then runny nose, high fever, nasal congestion and cough in companied symptom. Conclusions : Bloodletting therapy and Alunitum-spread were useful to improve acute tonsillitis.

• 한방안이비인후피부과학회지
• /
• 제27권4호
• /
• pp.221-229
• /
• 2014

손발에 수포를 형성하고 스트레스에 민감하며 수족다한증에서 호발하는 한포진을 한의학적으로 비주사말(脾主四末)이 되지 않은 상태와 스트레스에 의한 심화(心火)의 범주에 속한다고 가정하고 사상의학(四象醫學)의 각 체질별 표병(表病)과 이병(裏病)에서 비주사말(脾主四末)의 개선과 심화(心火)를 해결할 수 있는 처방들을 투여하여 환자 3례에서 유효한 치료효과를 얻었기에 치험례로 보고하는 바이다. 향 후 다른 처방들에 대한 사상의학적 연구도 필요할 것으로 사료된다.

• 한방안이비인후피부과학회지
• /
• 제36권1호
• /
• pp.1-20
• /
• 2023

Objectives : The purpose of this study was to evaluate the anti-inflammatory effect of Tanghwajitongsan(THJTS) through inhibition of NF-κB and MAPK. Methods : We evaluated cell survival rate by MTT assay, NO production by nitrite content in the culture medium. We quantified TNF-α, IL-1β, IL-6 and PGE₂ of the cultured supernatant by ELISA. And we evaluated the effect of THJTS on protein expression of NF-κB, MAPK, iNOS and COX-2 by Western blot analysis. THJTS ameliorates LPS-activated alterations in protein expression of NF-κB, p-38, iNOS and COX-2 and production of NO, pro-inflammatory cytokines and PGE₂. Also, THJTS ameliorates LOX, PGN and FLA-activated alterations in protein expression of NO, iNOS. THJTS ameliorates only PGN-activated alterations in protein expression of COX-2. Results : THJTS ameliorates LPS-activated alterations in protein expression of NF-κB, p-38, iNOS and COX-2 and production of NO, pro-inflammatory cytokines and PGE₂. Also, THJTS ameliorates LOX, PGN and FLA-activated alterations in protein expression of NO, iNOS. THJTS ameliorates only PGN-activated alterations in protein expression of COX-2. Conclusions : This study can provide scientific evidence for the anti-inflammatory effects and underlying mechanisms of THJTS.

• 대한한의학회지
• /
• 제31권5호
• /
• pp.179-187
• /
• 2010

임상에서 치료가 어려운 건선을 오래 앓아온 환자가 홍피성 건선이 발생하여 집중적인 입원치료 후 꾸준한 외래진료를 거쳐 호전된 경과를 볼 수 있었기에 보고하는 바이다. 상기 환자는 심장 질환을 동반하고 있었으며 그와 관련된 부종 등의 증상에도 한방치료로 긍정적인 효과를 얻었다. 앞으로 홍피성 건선의 한방치료에 대한 치료의 기준을 마련할 필요가 있을 것으로 생각된다.

• 한방안이비인후피부과학회지
• /
• 제29권1호
• /
• pp.65-80
• /
• 2016

Objective : The purpose of this study is to report the hair regrowth effect of Gagamyeonryunggobon-dan on ICR mice from measuring the change of diverse factors.Methods : Gagamyeonryunggobon-dan was treated by oral administration with 2.5㎎/㎏/day amount for 3 weeks per mouse everyday. Hair regrowth was estimated by change of morphology, angiogenesis, hair follicle activation. The change of morphology was observed with external, internal change and sebaceous gland. Angiogenesis was estimated by image analysis, capillary distribution and angiogenic chemokine(MIP-2). Hair follicle activation was estimated by PCNA, IGF-2 and serotonin.Results : 1. Gagamyeonryunggobon-dan treated group had more and thicker hairs than the group not treated. Especially well developed sebaceous glands were seen in dermis of treated group. 2. Gagamyeonryunggobon-dan treated group had more capillaries near hair follicles of subcutaneous layer and more 2019% MIP-2 positive activity than the group not treated. 3. Gagamyeonryunggobon-dan treated group increased positive activity up to 596% in PCNA, 187% in IGF-2 and 547% in serotonin more than the group not treated.Conclusion : These results shows that Gagamyeonryunggobon-dan have the hair regrowth effect through verifying change of morphology, angiogenesis, chemokines. Consequently Gagamyeonryunggobon-dan is expected to apply to take care of extensive hair loss symptoms.

• 한방안이비인후피부과학회지
• /
• 제29권3호
• /
• pp.14-26
• /
• 2016

Objectives : This study was performed to investigate the protective effects and mechanisms of Salvia miltiorrhizae Radix extract (SME) on endotoxin shock.Methods : We used two models; LPS-induced sepsis model for in vivo model, and murine peritoneal macrophages responses for in vitro. SME was administrated orally to mice. After 1 hr, LPS was injected intraperitoneally. Survival rate was checked each time per 12 hr for 5 days. Mice were sacrificed 3 hr after LPS injection, then blood samples and organs were harvested. Cytokines secretion was measured by ELISA. Organs tissues were observed with microscope. Murine peritoneal macrophages were cultured for 1 hr either in a medium alone or in a medium that contained SME, as indicated. Then, the cells were treated with LPS for 24 hr. mRNA levels of cytokines were measured by real-time RT-PCR. Cytokine levels in the supernatants were measured by ELISA. The amount of nitrite was measured by using the Griess method to evaluate NO production. The cell lysates were analysed by Western blotting using antibodies for iNOS and β-actin was used as an internal control to monitor equal protein loading.Results : SME improverd the survival rate of mice model. SME inhibited the secretion of inflammatory cytokines and organs damages on Endotoxin Shock model. SME suppressed cytokine expression, cytokine secretion,NO production, iNOS expression in LPS-induced murine peritoneal macrophages.Conclusions : The results suggest that SME has protective effects on endotoxin shock through suppression of inflammatory cytokines, organ damages, NO production and so on.