• 동의생리병리학회지
• /
• 제22권1호
• /
• pp.176-182
• /
• 2008

Scolopendra was known to cure erectile dysfunction. This study was aimed to investigate the effects of Scolopendra on the nitric oxide synthase activity, nitrite level, cyclic-GMP and erectile responses in rat's corpus cavernosum penis. The crushed Scolopendra was extracted 3 times, each time with 3 volumes of methyl alcohol at $60^{\circ}C$ for 24 h. The extract was filtered and evaporated under a reduced pressure using a rotary evaporator to yield 14.2 g. Scolopendra extract was oral-administered 50 mg per 1 kg of body weight for 30 days. First, samples were treated with Scolopendra, and then ethanol-treated rats and L-N-Nitroarginine methyl ester (L-NAME) treated rats were fed with the samples. The level of urethral nitrite and nitric oxide synthase activity in the ethanol-Scolopendra double administered rats were as high as in the normal group, while the one in the ethanol-treated group was decreased. The level of urethral cyclic-GMP and guanylate cyclase actiyity in the ethanol-Scolopendra double administered rats were as high as in the normal group, while the one in the ethanol-treated group was decreased. The level of urethral phosphodiesterase activity in the ethanol-Scolopendra double administered rats was as low as in the normal group, while the one in the ethanol-treated group was increased. The erectile response to a cavernous nerve stimulation in L-NAME $(10^{-4})-treated$ rats was restored by the Scolopendra to the similar level seen in the normal group. The electile response to cavernous nerve stimulation in the ethanol-Scolopendra double administered rats were increased as high as in the normal group while the one in the ethanol-treated group was decreased. Scolopendra was effective in restoring the ethanol-induced or L-NAME-induced erectile dysfunction in rats.

• 동의생리병리학회지
• /
• 제25권2호
• /
• pp.234-241
• /
• 2011

Mantidis Vagina Ovorum was formulated to contain various natural products known to cure erectile dysfunction. This study was aimed to investigate the effects of Mantidis Vagina Ovorum on the nitric oxide synthase (NOS) activity, nitrite level, antioxidation and erectile responses in rat's corpus cavernosum penis. The crushed Mantidis Vagina Ovorum was extracted 3 times, each time with 3 volumes of methyl alcohol at $60^{\circ}C$ for 24 h. The extract was filtered and evaporated under a reduced pressure using a rotary evaporator to yield 16.6 g. Mantidis Vagina Ovorum extract oral-administered 75 mg per 1 kg of body weight for 30 days. First, samples were treated with Mantidis Vagina Ovorum, and then cimetidine-treated rats and L-N-Nitroarginine methyl ester (L-NAME) treated rats were put with the samples. The level of urethral lipid peroxide in the cimetidine-Mantidis Vagina Ovorum double administered rats was decreased as low as in the normal group, while the one in the cimetidine-treated group was increased. The urethral NOS activity, the level of urethral nitrite, the level of testosterone and the electile response to cavernous nerve stimulation in the cimetidine-Mantidis Vagina Ovorum double administered rats were increased as high as in the normal group while the one in the cimetidine-treated group was decreased. The electile response to cavernous nerve stimulation and the level of nitrite in L-NAME ($10^{-4}$)-treated rats was restored by the administration of Mantidis Vagina Ovorum as high as in the normal group. Mantidis Vagina Ovorum was effective in restoring the cimetidine-induced or L-NAME-induced erectile dysfunction in rats.

• 한국수산과학회지
• /
• 제55권3호
• /
• pp.353-373
• /
• 2022

Many fish species are imported into Korea from various countries. However, in the case of some fish species, there are many that do not have Korean names. Species similar in morphology to domestically produced aquatic products are often disguised as being domestically produced and distributed. Therefore, this study presents a species list for 1,032 fish imported into Korea. Fish species that have not been given Korean names have been given a Korean name using a scientific method to prevent confusion during seafood distribution. Standards for naming stingrays, skates, and mackerel, which are often confused when a country name is being assigned are presented.

• Journal of Species Research
• /
• 제9권3호
• /
• pp.233-246
• /
• 2020

A scientific name is one of changeable terms in biology whenever additional research results of specific taxa is accumulated. The Database of the National Species List of Korea (DBNKo) was developed to manage taxonomic information of Korean species, designed to describe the changeable and complex taxonomical structure and information. A Korean Taxonomical Serial Number (KTSN) was assigned to each taxon, different from the normally used systems that the scientific name was considered as primary key to manage higher rank of taxa systematically. Common names were also treated with the KTSN, reflecting that common name is considered as one type of taxon. Additional taxonomic information (e.g., synonyms, original names, and references) was also added to the database. A web interface with an intuitive dashboard presenting taxonomic hierarchical structure is provided to experts and/or managers of the DBNKo. Currently, several biological databases are available in the National Institute of Biological Resources (NIBR) such as a specimen database, a digital library, a genetic information system, and the shared species data based on the DBNKo. The DBNKo started sharing species information with other institutions such as the Nakdonggang National Institute of Biological Resources. It is an ideal centralized species database to manage standardized information of Korean species.

• 대한본초학회지
• /
• 제28권5호
• /
• pp.29-31
• /
• 2013

Objectives : 'Reconsideration about Nomenclature of Herbs Listed in the Korean Pharmacopoeia' was published by Doh and Lee with absolute misconception of nomenclature. A critical review of Doh and Lee's paper is given, to correct the confused the concept of nomenclature and to provide proper scientific name for taxa which are discussed. Methods : This paper discusses the proper usage, as mandated by the International Code of Nomenclature. Adherence to the rules described in this paper should reduce the present confusion in the nomenclature of scientific names listed in the Korean Pharmacopoeia. Results : Although Doh and Lee proposed four categories to correct the scientific names of the Korean Pharmacopoeia using available botanical databases, they failed to show how nomenclatural concepts are applicable due to misconception of legitimacy and the confusion about synonym. From a nomenclatural perspective, 'accepted name' or 'recommended name' is a subjective term which used to be employed for convenience in a certain databases or working group without nomenclatural meaning. Doh and Lee also pointed out the standardization of author citation. However, they missed the importance of author citation error such as basionym or validating authors. Conclusions : Doh and Lee were not able to solve nomenclatural problems of the Korea Pharmacopoeia due to lack of clarity on the nomenclature code. We strongly recommend that KFDA has to commence extensive nomenclatural review for the next revision of Korea Pharmacopoeia.

• 한국전자통신학회논문지
• /
• 제19권4호
• /
• pp.701-708
• /
• 2024

딥러닝 분야에서 트랜스포머 아키텍쳐의 출현은 자연어 처리 연구가 획기적인 발전을 가져왔다. 개체명 인식은 자연어 처리의 한 분야로 정보 검색과 같은 태스크에 중요한 연구 분야이다. 생의학 분야에서도 그 중요성이 강조되나 학습용 한국어 생의학 말뭉치의 부족으로 AI를 활용한 한국어 임상 연구 발전에 제약이 되고 있다. 본 연구에서는 한국어 생의학 개체명 인식을 위해 새로운 생의학 말뭉치를 구축하고 대용량 한국어 말뭉치로 사전 학습된 언어 모델들을 선정하여 전이 학습시켰다. F1-score로 선정된 언어 모델의 개체명 인식 성능과 태그별 인식률을 비교하고 오류 분석을 하였다. 인식 성능에서는 KlueRoBERTa가 상대적인 좋은 성능을 보였다. 태깅 과정의 오류 분석 결과 Disease의 인식 성능은 우수하나 상대적으로 Body와 Treatment는 낮았다. 이는 문맥에 기반하여 제대로 개체명을 분류하지 못하는 과분할과 미분할로 인한 것으로, 잘못된 태깅들을 보완하기 위해서는 보다 정밀한 형태소 분석기와 풍부한 어휘사전 구축이 선행되어야 할 것이다.

• 패션정보와 기술
• /
• 제2권
• /
• pp.14-21
• /
• 2005

• 한국수학사학회지
• /
• 제12권1호
• /
• pp.53-64
• /
• 1999

We have studied the idealistic numeration which has been used in Chinese classics of Korea. The form is $\circled4$ of the