• Toxicological Research
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• 제13권1_2호
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• pp.127-130
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• 1997

Acute toxicity of EPO(Erythropoietin) was investigated using rats and beagle dogs according to Established Regulation of Korean National Institute of Safety Research (1994. 4. 14). Rats and beagle dogs were injected intravenously with dosages of 20000 IU/kg, 2000 IU/kg, 200 IU/kg, 20 IU/kg and 2 IU/kg. In animals injected with EPO, there were neither dead animals nor significant changes of body weights. In addition, no differences were found between control and treated groups in clinical signs and autopsy findings. Therefore $LD_50$ of EPO was considered to be higher than 20000 IU/ kg B. W. in rats and beagle dogs.

• 대한수의학회지
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• 제55권3호
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• pp.205-208
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• 2015

Ten dogs were enrolled in this study: two healthy dogs, two obese dogs without other medical issues and six obese dogs with underlying diseases including pemphigus, chronic active hepatitis, hyperadrenocorticism, narcolepsy, otitis media and heartworm infection. Pyrosequencing of the 16S rRNA gene to explore the gut bacterial diversity revealed that distal gut bacterial communities of samples from patients with pemphigus, otitis media and narcolepsy consisted primarily of Firmicutes, while the major phylum of the distal gut bacterial communities in patients with chronic active hepatitis and hyperadrenocorticism was Fusobacteria. Proteobacteria were the dominant phylum in heartworm infected obese patients.

• 대한수의학회지
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• 제59권4호
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• pp.213-217
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• 2019

Five paraplegic dogs were diagnosed with thoracolumbar intervertebral disc disease with more than 50% compression of spinal cord. Because the lesions were determined to be disc extrusion on magnetic resonance imaging, a hemilaminectomy was initially performed, however, protruded discs were confirmed during surgery. To remove the protruded disc, modified partial lateral corpectomy (mini-PLC) was additionally performed. All dogs recovered to full ambulation within a median of 44 days without temporary deterioration or vertebral instability. Mini-PLC as described here enables successful removal of the protruded disc, while preserving vertebral stability in dogs for whom the use of hemilaminectomy is inevitable.

• 한국동물위생학회지
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• 제22권1호
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• pp.25-35
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• 1999

The prevalence of canine heartworm(Dirofilaria immitis) infection in 150 mixed-breed dogs(male : 54, female : 96) from February to December 1997 was investigated by using antigen test kit(ICT $GOLD^{TM}$ HW, Synbiotics, USA) based on immunochromatographic assay in Inchon city. Also, gross and histopathological findings of an antigen positive dog were carried out. The results were summarized as follows ; 1. Four dogs were positive from 150 tested dogs(2.7%). They were all more than 2 years old and infection rates in male and outdoor dogs was higher than those in female and indoor, respectively. Species of infected dogs were Pug(2) , German Sheperd(1) and Great-dane (1). 2. Regional infection rates were closely related with housing system in the city. 3. Pathological findings of antigen-positive dog was excessive enlargement, congestion and hemorrhage of lung and D immitis in heart and histologically hemosiderin, hypertrophy of pulmonary alveoli wall and irregular hypertrophy of pulmonary artery inner wall. Microfilaria was observed in pulmonary artery and arteriole, ventricle and splenic artery.

• 대한수의학회지
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• 제22권2호
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• pp.259-263
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• 1982

Observations were made on the infection rate of common internal parasites in dogs in Kwangju area from January to March, 1982. Dog's stools were collected from veterinary hospitals, houses, intensive dog-rearing places and sidewalks. On the basis of egg counting, the following results were obtained; 1. Of 464 fecal samples, 73.5% were appeared as positive. 2. Dogs from veterinary hospitals and intensive dog-rearing places have higher infection rates than others. 3. Of the parasites detected, Toxocara canis was the most commonly encountered (23.7%). 4. Ascarids, flukes and coccidia were more prevalent in pups than in mature dogs, whereas bookworms were detected less often in young dogs than in older ones. 5. There were significant (p<0.01) differences among age categories for all parasites except tapeworms.

• 대한수의학회지
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• 제49권2호
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• pp.173-177
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• 2009

This study examined the efficacy of apitoxin for the treatment of otitis externa in dogs. Ten dogs with otitis externa were allocated randomly to two groups. The control group was treated with the susceptible antibiotics and the experimental group was injected with apitoxin into the tragus subcutaneously. There were no significant differences in the clinical scores, blood WBC counts and neutrophil/lymphocyte ratios between the control and experimental groups. By 2 weeks, the bacterial cell counts were significantly lower in the experimental group than the control (p < 0.05). No adverse reactions were observed in any of the dogs during the study. This suggests that a topical injection of apitoxin is an effective treatment for otitis externa in dogs.

• 한국동물위생학회지
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• 제33권1호
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• pp.23-27
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• 2010

This survey was performed to investigate the seroprevalence of antibodies to Brucella canis in dogs from public animal shelters and breeding kennels in Incheon. A total of 402 dogs selected randomly were tested serologically by using immunochromatographic antibody test kit. None of 289 dogs in public animal shelters were sero-positive and 10 (8.9%) of 113 dogs in breeding kennels were sero-positive. 5 (4.4%) strains of Brucella canis were isolated from 10 sero-positive dogs' blood. Antimicrobial susceptibility test was carried out by Disk diffusion method. They were susceptible to tetracyclines, quinolones, aminoglycosides and combination amoxicillin with clavulanic acid.

• 한국동물위생학회지
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• 제16권2호
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• pp.138-143
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• 1993

This study was performed to examine the distribution of dermatophytes in asymptomatic 454 dogs and 106 cats and in 19 dogs with skin lesions in Taegu. The results obtained were summarized as follows ; 1. The isolation rates of dermatophytes were 10.1% (46/454) in asymptomatic dogs and 33.0%(35/106) in asymptomatic cats. 2. The isolation rates of dermatophytes in dogs and cats were lower at house than that at pet cannel and animal care center, and that in females were higher than that in males, 3. From dog, 43(93.5%) of M canis and 3(6.5%) of M gypseum, and from cats, 33(94.2%) of M canis, 1(2.9%) of M gypseum and M nunum were isolated.

• 대한수의학회지
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• 제59권3호
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• pp.171-173
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• 2019

Two dogs presented with vomiting and head pressing. In both dogs, a large vessel was revealed in computed tomography (CT) angiography, which was found to leave the portal vein (PV) cranial to the splenomesenteric confluence and enter the pre-hepatic caudal vena cava cranial to the right renal vein. The flow of portal blood to the liver was not identified. Based on CT angiography, the dogs were suspected to have congenital PV aplasia with portocaval shunting. Diagnostic imaging of potential malformations for PV continuation should be conducted before attempting shunt closure.

• 대한수의학회지
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• 제61권1호
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• pp.5.1-5.7
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• 2021

The goal of this study was to measure immunoglobulin G4 (IgG4) concentrations and to evaluate the significance of these values in the management of canine pancreatitis. The medical records of 24 dogs that visited the Veterinary Medical Teaching Hospital between December 2016 and June 2018 were retrospectively reviewed to identify dogs that had been diagnosed with pancreatitis. The serum C-reactive protein and serum IgG4 concentration in the affected dogs were highly increased compared to the healthy group. Particularly, serum IgG4 measured significantly higher in dogs with pancreatitis and concurrent immune-mediated disease (p < 0.05). In conclusion, increased serum IgG4 concentrations are a characteristic finding in dogs with pancreatitis. The results of this research indicate that an elevation in IgG4 has the potential of being used as a tool for the diagnosis of pancreatitis and concurrent immune-mediated disease.