• Journal of muscle and joint health
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• v.25 no.2
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• pp.122-134
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• 2018

Purpose: The purpose of this study was to develop a 12-week structured exercise program (12-week-SEP) and evaluate its effects on pain, physical function and quality of life in patients with total hip arthroplasty (THA). Methods: A nonequivalent control group non-synchronized design was utilized to examine the effects of the 12-week-SEP on patients' outcomes after THA. A total of 46 adult patients (experimental group=25, control group=21) who had THA were recruited for the study. The 12-week-SEP consisted of education, exercise (muscle strengthening and progressive walking), and feedback. Data were analyzed by SPSS/WIN 21.0 using the $x^2$ test and repeated measures ANOVA. Results: The mean age of the participants was 60.9 years and 25 men (54.5%) and 21 women (45.7%) were included in the study. There were significant intervention effects on pain reduction and increased physical function but no effects on quality of life. Conclusion: The 12-week-SEP provided pain relief and enhanced physical function in patients underwent THA. Clinical application of the 12-week-SEP can improve postoperative nursing practices for patients with THA. Future research with larger sample is of necessity to obtain greater generalizability of the empirical evidences of the 12-week-SEP.

• Human Ecology Research
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• v.54 no.3
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• pp.227-238
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• 2016

This study investigates the mediation effects of adult children's ambivalence for elderly parents in the relation of psychological well-being of middle aged children with dependence and the intrusiveness of elderly parents that examines the difference of mediation effects by children's gender. We collected data from 659 middle aged children of 40 to 59 years old who have living mother or father. The main findings are as follows. First, there were mediation effects of ambivalence for elderly parents in the relation between psychological well-being of middle aged children and dependency and intrusiveness of elderly parents. The perceived dependence and intrusiveness of elderly parents had a positive influence on the ambivalence of middle aged childen for their elderly parents. Ambivalence for elderly parents had a negative effect on the psychological well-being of middle aged children. In addition, the dependence and intrusiveness of elderly parents did not directly influence the psychological well-being of middle aged children. Second, the mediation effect of ambivalence for elderly parents indicated a gender difference of middle aged children. The dependence of elderly parents affected the ambivalence for elderly parents in the woman group and the intrusiveness of elderly parents only affected ambivalence for elderly parents in the man group. The results were discussed in terms of gender difference.

• Applied Microscopy
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• v.36 no.1
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• pp.25-33
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• 2006

This study applied a bleaching agent. which is commonly used in the beauty salons, to the hair of normal adult women, collected the hair immediately and 10 days and 20 days from the bleaching, were investigated the degree of degradation of the hair by using scanning and transmission electron microscopes. The surface of hair just after bleaching was observed to be similar to that of normal hair, showing no split or damage of scale. In the hair of 10 days after bleaching, however, the scale came off. From this time, scale on the cuticular layer of hair began to be separated. In 10 days from bleaching, the scale on the cuticular layer was separated from hair and some cytoplasm of cuticular cells was broken into pieces or fell off. The cell remains made the surface coarse and uneven. At this period, damaged scales had a sharp end. In the hair of 20 days after bleaching, scale fell off from the whole surface of the hair and the surface looked rough. On the bleached hair, many vacuoles were formed in the endocuticle of cuticular cells. As a result, deformation caused by the formation of vacuoles in cuticles broke up the cuticular cells.

• Journal of radiological science and technology
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• v.28 no.3
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• pp.227-234
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• 2005

- Objective Osteoporosis is one of the characteristic adult diseases, high prevalence, many complications, easy fracture, important health problem. this study, compared analysis BMD data of the lumbar spine and femur - Methods For the 100 female patients,

• Journal of Periodontal and Implant Science
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• v.51 no.5
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• pp.316-328
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• 2021

Purpose: This study aimed to examine the prevalence and abundance of 9 representative periodontal pathogens in the saliva samples of periodontally healthy subjects (PH) and patients with periodontitis who underwent supportive periodontal therapy (SPT). The age-specific distribution of these pathogens in periodontally healthy individuals was also analyzed. Methods: One hundred subjects (aged >35 years) were recruited (50 each in the PH and SPT groups) between August 2016 and April 2019. The prevalence and abundance of periodontal pathogens in the PH group were compared with those in periodontally healthy young subjects (94 subjects; aged <35 years), who were included in our previous study. DNA copy numbers of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn), Campylobacter rectus (Cr), Peptostreptococcus anaerobius (Pa), and Eikenella corrodens (Ec) were analyzed using real-time polymerase chain reaction. Results: The detection frequencies of all pathogens, except Aa, were high in the PH and SPT groups. The ranking order of pathogen DNA copy numbers was similar in both groups. In both groups, Fn had the highest abundance, Aa had the lowest abundance. Additionally, Td was significantly more abundant in men than in women in both groups (P<0.05). Compared with the PH group, the SPT group exhibited significantly lower total bacteria and Fn abundance and higher Pg abundance (P<0.05). The age-specific pathogen distribution analysis revealed a significantly low Aa abundance and high Tf and Cr abundance in the PH group. Conclusions: The clinical parameters and microbial profiles were similar between the SPT and PH groups. However, patients with periodontitis require supportive care to prevent recurrence. As the abundance of some bacteria varied with age, future studies must elucidate the correlation between age-related physiological changes and periodontal bacterial composition.

• Toxicological Research
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• v.35 no.1
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• pp.9-12
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• 2019

One of the major challenges in methadone maintenance therapy (MMT) for drug dependence is the physiological side effects on endocrine hormones. Because of the key role of the thyroid gland in the normal functioning of the human body and brain, this study examined the effect of MMT on thyroid function. Thyroid hormones (T3, T4, and thyroid-stimulating hormone (TSH)) were evaluated in normal and user treated with MMT who were referred to the Province Clinical & Pathology Center of Urmia, Iran. The study was conducted for three months using the Case Series method. A total of 270 samples were collected, 215 were from individuals who were not treated, whereas 55 were from men treated with methadone. Average levels of T3 and T4 in non-treated sample of men are $1.34{\pm}0.02ng/mL$ and $90.96{\pm}1.38ng/mL$ while the corresponding values for patients treated with methadone are $1.39{\pm}0.04ng/mL$ for T3 and $94.57{\pm}2.72ng/mL$ for T4. Mean TSH levels of the non-treated group and the methadone consuming group were $1.75{\pm}0.08{\mu}IU/mL$ and $3.17{\pm}0.45{\mu}IU/mL$, respectively. These results indicate that although men treated with methadone had higher levels of T3, T4, and TSH than normal individuals, only the difference in TSH level was significant. The importance of this difference among individuals on methadone maintenance programs should be investigated in larger samples over long periods of time. Additionally, the effects of methadone treatment on women should be examined.

• Journal of Chest Surgery
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• v.54 no.1
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• pp.45-52
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• 2021

Background: Atrial septal defect (ASD) is the most common congenital heart disease. However, the details of cardiac chamber remodeling after surgery are not well known, although this is an important issue that should be analyzed to understand long-term outcomes. Methods: Between November 2017 and January 2019, cardiac magnetic resonance imaging was performed preoperatively, at a 1-month postoperative follow-up, and at a 1-year postoperative follow-up. Cardiac chamber volume, valve regurgitation volume, and ejection fraction were measured as functions of time. Results: Thirteen patients (10 men and 3 women) were included. The median age at surgery was 51.4 years. The preoperative median ratio of flow in the pulmonary and systemic circulation was 2.3. The preoperative mean right ventricular (RV) end-diastolic volume index (EDVi) and RV end-systolic volume index (ESVi) had significantly decreased at the 1-month postoperative follow-up (p<0.001, p=0.001, respectively). The decrease in the RVEDVi (p=0.085) and RVESVi (p=0.023) continued until the postoperative 1-year follow-up, although the rate of decrease was slower. Tricuspid valve regurgitation had also decreased at the 1-month postoperative follow-up (p=0.022), and continued to decrease at a reduced rate (p=0.129). Although the RVEDVi and RVESVi improved after ASD closure, the RV volume parameters were still larger than the left ventricular (LV) volume parameters at the 1-year follow-up (RVEDVi vs. LVEDVi: p=0.016; RVESVi vs. LVESVi: p=0.001). Conclusion: Cardiac remodeling after ASD closure is common and mainly occurs in the early postoperative period. However, complete normalization does not occur.

• Journal of Convergence for Information Technology
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• v.10 no.12
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• pp.156-165
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• 2020

330 Korean adult women were examined the correlation between degree of makeup and makeup satisfaction before/after wearing masks due to COVID-19 and the moderating effect of mandatory/voluntary goal-oriented attitude toward makeup. The study found that lip makeup(p<.001) was significant variable in makeup satisfaction before COVID-19, and eyebrow makeup(0<.002) was significant after COVID-19. Although moderating effect of mandatory goal-oriented attitude, which works between degree of makeup before/after COVID-19 and makeup satisfaction was not significant, but moderating effect of voluntary goal-oriented attitude appeared to be significant before(p<.000) and after(p<.000) COVID-19. And the degree of makeup after COVID-19 was lower than before(p<.000). If one believe that makeup is for one's own satisfaction, degree of makeup can be significant effect on the makeup satisfaction, but actual behavior has shown that degree of makeup has decreased since wearing masks because of COVID-19. I hope this research will be used as marketing material for beauty and cosmetics industry.

• Microbiology and Biotechnology Letters
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• v.50 no.2
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• pp.283-292
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• 2022

Colibactins (clb) and Cytotoxic Necrotizing Factors (cnf) are virulence factors that impact cell cycle through cellular differentiation, proliferation, and apoptosis. Urinary tract infections (UTIs) are the most common among type of infection among outpatients, with a lifetime incidence of about 60-65% in adult females. Here, we sought to isolate uropathogenic Escherichia coli (UPCE) from urine specimens and investigates the prevalence of clb A, B and cnf 1, 2 genes among these isolates. A total of 110 E. coli isolates were collected from patients with UTIs. All the isolates were examined for their hemolytic activity and only 46 isolates showed a halo zone of hemolysis on blood agar. The collected UPEC isolates were screened for the existence of clb A, B and cnf genes. The results revealed that out of 110 isolates, 28 harbored the clbA gene, 40 harbored clb B, and 24 isolates harboured cnf1. 13 isolates harbored clbA, clbB, and cnf1 genes, while no cnf2 gene was detected among isolates. The molecular detection revealed that 8 out of 28 hemolytic isolates carrying the clbA, 11 out of 40 were carrying clbB, 1 out of 24 were carrying cnf 1, and 5 out of 9 carrying clbA+clbB. Furthermore, 7 out of 13 isolates were hemolytic and carrying clbA, clbB, and cnf1 genes. Finally, we investigated the cytotoxicity of E. coli harboring clb and cnf genes, eukaryotic REF cells were exposed to E. coli producing colibactin, which induces DNA damage and leads to cell cycle arrest, senescence and death.

• Korean Journal of Exercise Nutrition
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• v.24 no.4
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• pp.15-23
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• 2020

[Purpose] Lactate is a principal energy substrate for the brain during exercise. A single bout of high-intensity interval exercise (HIIE) can increase the blood lactate level, brain lactate uptake, and executive function (EF). However, repeated HIIE can attenuate exercise-induced increases in lactate level and EF. The lactate levels in the brain and blood are reported to be correlated with exercise-enhanced EF. However, research is yet to explain the cause-and-effect relationship between lactate and EF. This study examined whether lactate consumption improves the attenuated exercise-enhanced EF caused by repeated HIIE. [Methods] Eleven healthy men performed two sets of HIIE, and after each set, 30 min were given for rest and examination. In the 2^nd set, the subjects consumed experimental beverages containing (n = 6) and not containing (n = 5) lactate. Blood, cardiovascular, and psychological variables were measured, and EF was evaluated by the computerized color-word Stroop test. [Results] The lactate group had a higher EF (P < 0.05) and tended to have a higher blood lactate level (P = 0.082) than the control group in the 2^nd set of HIIE. Moreover, blood lactate concentration was correlated with the interference score (i.e., reverse score of EF) (r = -0.394; P < 0.05). [Conclusion] Our results suggest that the attenuated exercise-enhanced EF after repeated HIIE can be improved through lactate consumption. However, the role of lactate needs to be elucidated in future studies, as it can be used for improving athletes' performance and also in cognitive decline-related clinical studies.