• Mass Spectrometry Letters
• /
• v.5 no.2
• /
• pp.52-56
• /
• 2014

Glycated hemoglobin (HbA1c) is used as an index of mean glycemia over prolonged periods. This study describes an optimization of enzyme digestion conditions for quantification of non-glycated hemoglobin (HbA0) and HbA1c as diagnostic markers of diabetes mellitus. Both HbA0 and HbA1c were quantitatively determined followed by enzyme digestion using isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) with synthesized N-terminal hexapeptides as standards and synthesized isotope labeled hexapeptides as internal standards. Prior to quantification, each peptide was additionally quantified by amino acid composition analysis using ID-LC-MS/MS via acid hydrolysis. Each parameter was considered strictly as a means to improve digestion efficiency and repeatability. Digestion of hemoglobin was optimized when using 100 mM ammonium acetate (pH 4.2) and a Glu-C-to-HbA1c ratio of 1:50 at $37^{\circ}C$ for 20 h. Quantification was satisfactorily reproducible with a 2.6% relative standard deviation. These conditions were recommended for a primary reference method of HbA1c quantification and for the certification of HbA1c reference material.

• New & Renewable Energy
• /
• v.16 no.1
• /
• pp.15-24
• /
• 2020

For mechanical load testing of wind turbines, capture matrix is constructed for various range of wind speeds according to the international standard IEC 61400-13. The conventional method wastes considerable amount of data by its invalid data policy -segment data into 10 minutes then remove invalid ones. Previously, we have suggested an alternative way to save the total amount of data to build a capture matrix, but the efficient selection of data has been still under question. The paper introduces optimization algorithms to construct capture matrix with less data. Heuristic algorithm (simple stacking and lowest frequency first), population method (particle swarm optimization) and Q-Learning accompanied with epsilon-greedy exploration are compared. All algorithms show better performance than the conventional way, where the distribution of enhancement was quite diverse. Among the algorithms, the best performance was achieved by heuristic method (lowest frequency first), and similarly by particle swarm optimization: Approximately 28% of data reduction in average and more than 40% in maximum. On the other hand, unexpectedly, the worst performance was achieved by Q-Learning, which was a promising candidate at the beginning. This study is helpful for not only wind turbine evaluation particularly the viewpoint of cost, but also understanding nature of wind speed data.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.10 no.4
• /
• pp.41-48
• /
• 2010

In this paper, a new type of integrated AFCI is designed and implemented by combining individual circuit breaker characteristics, which can effectively detect arc fault signals in real-time. The proposed integrated AFCI satisfies the UL1699, the USA certification standard, and the Korean circuit breaker standards such as KS C4613 and KS C8321. Data signals are transferred to the management server via ZigBee network to analyze dangerous factors and to prevent unwanted trip. It is also shown by experiments that arc fault signals are detected and analyzed by using the integrated AFCI with ZigBee networks.

• New & Renewable Energy
• /
• v.9 no.1
• /
• pp.33-43
• /
• 2013

The objective of this paper is to provide a review on the latest development on the main initiative and approaches for the sustainability criteria for biofuels. A large number of national and international initiative lately experienced rapid development in the review of the biofuels targets announced in the European Union (EU), United States (US) and other countries worldwide. The global biofuel targets are likely to have a strong impact on land use and agricultural markets. Although biofuels production provides new options for using agricultural crops, there are environmental, social and economic concerns associated with biofuel production. The diversity of feedstock, large number of biofuels pathway an their complexity lead to a high uncertainty over the greenhouse gas (GHG) performances of biofuels, in terms of GHG emission reductions compared to the fossil fuels, expecially if land use change is involved. This paper describes an overview of current status of ongoing certification initiative in Europe and worldwide for biofuels sustainability. It also provides mandatory requirements as part of an sustainability scheme in EU, United Kingdom, US and international approaches and should be reviewed to introduce based on global trends in Korea.

• Korean Journal of Computational Design and Engineering
• /
• v.16 no.2
• /
• pp.92-103
• /
• 2011

The construction industry consists of various and massive architectural information as an architectural process includes a variety of design stages with cooperation of many disciplines. A Building Information Modeling (BIM) serves as a shared knowledge resource for information about a facility forming a reliable basis for decisions during its life-cycle from inception onward. building SMART has developed Industry Foundation Classes (IFC) standard for interoperability of BIM based information. Several software tools are already IFC-compliant. However, there are a lot of problems related to efficient interoperability of software owing to the lack of guide regarding the software usage and insufficiency IFC interfaces of software. The purpose of this study is to suggest efficient IFC support interface development methodologies of existing IFC certified software. The scope of this study is interoperability test for open BIM based quality assurance. To achieve this purpose, the authors have classified subject of open BIM based quality assurance and investigated IFC certification process and certified software. In addition, the authors have exported and imported via IFC files using different IFC interfaces in the software for interoperability of architectural objects and their properties. Finally, the authors have suggested IFC support interface development methodologies and hereafter direction for efficient interoperability of IFC certified software based on open BIM.

• Journal of Fisheries and Marine Sciences Education
• /
• v.28 no.2
• /
• pp.417-427
• /
• 2016

It is provided that the seaman should be educated and trained by basic fire-fighting to save the life and protect asset at sea by the STCW(The International Convention on Standard for Training, Certification and Watchkeeping). The designated seaman's safety educational institution which is specified in the nation has held a basic and advanced fire-fighting education for the seaman. The interest of safety at sea has been increasing due to recent huge maritime disaster and there is a tendency to strengthen the safety education for the seaman in the nation. For the effective fire-fighting education for the seaman, the appropriate educational content and facilities are required. Moreover, It is necessary to apply an effective education and training methods for achieving the goal. Unfortunately, this paper has not perfectly been conducted to improve effective safety training in the designated educational institutions which held the seaman's maritime safety educations. From now on, we should consider the effective educational ways for the seaman. The purpose of this paper is to develop the education and training model of STCW seaman's fire-fighting education through the reviewing the status of safety education in the nation.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.25 no.2
• /
• pp.49-54
• /
• 2013

In field of apartment housing currently, insulation technology is the most effective way because it is common to improve the thermal performance, therefore, it is contributed to energy saving as several regional insulation standards and legal mandate method. In addition, by applying of building energy efficiency rating certification system, it has inspired voluntary energy conservation commitment for the building owner or facility manager by making a plan to evaluate and verify building energy performance. However, these circumstances are not enough to acquire a grade 2 of higher information. Therefore, in this study, we analyzed the impact of building energy efficiency rating and confirmed reduction ratio compared to the standard housing on the basis of recent our nation building law when we had changed the shape of windows and wall insulation performance and shapes of housing.

• International Journal of Quality Innovation
• /
• v.3 no.2
• /
• pp.159-173
• /
• 2002

Any organization's Six Sigma program may be at high risk without heeding the lessons learned from the past and that tries to operate without a robust business foundation. A foundation that preferably should consist of stepping-stones such as a 5-S house-keeping program, an effective Integrated Management System (IMS), which includes a strong focus on planning for quality to fully capture the Voice of the Customer (VOC), and an organization-wide training scheme, as well as a reliable Cost of Poor Quality (COPQ) system. That's the best advise I can give to any organization that wishes to embark on a Six Sigma improvement program and hope to be successful. The paper will elaborate on the above issues and provide suggested solutions based on the review of published historical information and the experiences encountered over the last four decades by the author, as a quality practitioner and consultant, in industries that produced safety-critical product. This author maintains that few fundamentally new or useful things have been created in the field of Quality during the last couple of decades. Nevertheless, this paper deliberates on a number of relatively “newer” issues including the concept of “three types of customers”, the CTC, “Critical To Customer” term, the eight Quality Management Principles of the new ISO 9000 family, the growth of industry-specific standards, the adoption of Integrated Management Systems, the rebirth of AS2561 COQ standard, the spread of Six Sigma as well as related ASQ certification and the need for a robust business foundation to ensure Six Sigma survival.

• Korean Journal of Agricultural Science
• /
• v.48 no.3
• /
• pp.617-627
• /
• 2021

In the field of on-road motor vehicles, the level for autonomous driving technology is defined according to J3016, proposed by Society of Automotive Engineers (SAE) International. However, in the field of agricultural machinery, different standards are applied by country and manufacturer, without a standardized classification for autonomous driving technology which makes it difficult to clearly define and accurately evaluate the autonomous driving technology, for agricultural machinery. In this study, a method to classify the autonomy levels for autonomous agricultural machinery (ALAAM) is proposed by modifying the SAE International J3016 to better characterize various agricultural operations such as tillage, spraying and harvesting. The ALAAM was classified into 6 levels from 0 (manual) to 5 (full automation) depending on the status of operator and autonomous system interventions for each item related to the automation of agricultural tasks such as straight-curve path driving, path-implement operation, operation-environmental awareness, error response, and task area planning. The core of the ALAAM classification is based on the relative roles between the operator and autonomous system for the automation of agricultural machines. The proposed ALAAM is expected to promote the establishment of a standard to classify the autonomous driving levels of self-propelled agricultural machinery.

• Journal of Engineering Education Research
• /
• v.24 no.2
• /
• pp.51-60
• /
• 2021

Although more than 15 years have passed since the introductory design courses were opened due to the introduction of engineering education certification in the civil engineering field, these courses have been operated somewhat unsatisfactorily compared to their importance as an introductory course for engineering design. This is partially because the quality of classes is affected by the instructor's individual ability due to the fact that a standard training plan for these courses has not been established so far. Therefore, in this paper, we try to present a reference model for the introductory design course by introducing a class operation case established through continuous improvement process over the last 10 years at Chungbuk National University. This case aims to cultivate students' problem solving and system design skills by carrying out projects to develop egg drop and wood bridge systems based on creative problem solving methodologies. As a result of a questionnaire survey conducted after the class, we found that students' problem solving and system design capabilities were improved significantly and there was a meaningful increase in level of interest and attention in civil engineering by taking this class.