• Korean Journal of Oriental Medicine
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• v.18 no.3
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• pp.133-139
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• 2012

Objective : UMLS is 'Ontology' which establishes the database for medical terminology by gathering various medical vocabularies representing same fundamental concepts. Method : Although Chinese character are represented in the Chinese part of Korean Unicode system in a computer, writing of Chinese characters is vary depending on Chinese input systems and Chinese writers' levels of knowledge. As the result of this, representation of Chinese writing in a computer will be considerably different from an old Chinese document. Therefore, a meaningful relationship between digital Chinese terminology and translated Korean is necessary in order to build Ontology for Chinese medical terms from Oriental medical prescription in a computer system. Result : This research will present 1:1 mapping information among the Chinese characters used in the Oriental medical prescription with analysis of 'same character different sound' and 'same meaning different shape' in Chinese part of Unicode systems. Conclusions : Furthermore, the research will provide top-down menu of relationship between Chinese term and Korean term in medical prescription with assumption of that the Oriental medical prescription has its own unique meaning.

• Herbal Formula Science
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• v.30 no.3
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• pp.183-189
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• 2022

Objective : This study aims to analyze the current use of body part terminology in Korean medicine formula data by comparing with ICD-11 body part terminology as a criteria. Methods : Body part terminology was extracted from the main treatment data within the Korean Medicine formula ontology and was analyzed in comparison with the ICD-11 body part terminology. Results : Out of 113 body part terminologies in Korean medicine, 92 were corresponded with ICD in a one-to-one, one-to-multi, or multi-to-one relation. Also, most body part terminologies were corresponded to superordinate concepts of ICD while 21 terminologies were not able to be corresponded to ICD. Conclusion : A majority of body part terminology in formula data could be corresponded to ICD but mostly refered to superordinate concepts. Results showed various types of corresponding relation which requires further study for precise and detailed correspondence. Also, study showed some terminologies were not applicable for correspondence which were mostly a unique body part concept of Korean medicine which requires further study to present Korean Medicine knowledge accurately in the language of ICD.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.894-899
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• 2011

Traditional Korean Medicine (TKM) has been actively researched through various approaches, including computational methods. This paper aims at providing an overview of domestic studies using the computational techniques in TKM field. A literature search was conducted in Korean publications using OASIS system, and major studies of data mining in TKM were identified. A review was presented in six diagnosis fields, including sasang constitution diagnosis, eight constitution diagnosis, tongue diagnosis, pattern diagnosis for stroke, diagnosis based on ontology, diagnosis for cause of disease. They collect clinical data themselves for experiments and primarily applied a algorithm of decision tree, SVM, neural network, case-based reasoning, ontology reasoning, discriminant analysis. In the future, there needs to identify which algorithm is suitable to diagnosis or other fields of TKM.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.6
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• pp.705-709
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• 2013

We in this paper proposed a distinction method to compare objects in the Korean medicine ontology. Comparing same and different information between two objects, two scenarios to use our system were designed and implemented. One is the distinction of formulas, medicinal materials, and acupuncture points and the other is the distinction of effects, treatments, and symptoms. To compare objects easily, the decomposition of effects and treatments and the processing of medicinal materials were provided. Also, information of each object was shown through the link to the semantic search system. Our distinction method and system could be helpful to compare and distinct two objects in the diagnosis systems or search systems of Korean medicine information.

• The Journal of the Society of Stroke on Korean Medicine
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• v.13 no.1
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• pp.63-70
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• 2012

Object : Traditional Korean Medicine Diagnostic Support System(TKMDSS) is the diagnostic prescribing system based on ontology developed by Korea Institute of Oriental Medicine. We monitored and assessed its usefulness and searched for improvements. Methods : We collected 10 cases of stroke inpatients of Dongguk University Ilsan Oriental Hospital. They were diagnosed by primary care physician and another researcher who monitored using "TKMDSS" respectively. We compared the process and results of two diagnosis. Results : The diagnostic concordance rate between primary care physician and researcher were pretty high. Most of the problems were caused by expressions on symptoms inappropriate use of terminology. The severity of symptoms and vague symptoms which is hard to be diagnosed should be reflected and measured in this system. Conclusions : The problems were about terminology and definition. The terminology should be defined accurately and in-depth detail so that anyone can get the right information. If the problems were modified, "TKMMSS" could be utilized as supportive measures for oriental medicine doctors and students.

• Herbal Formula Science
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• v.31 no.4
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• pp.295-313
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• 2023

Objectives : While treatments for cancer are advancing, the development of effective treatments for cancer metastasis, the main cause of cancer patient death, remains insufficient. Recent studies on Dichroae Radix have revealed that its active ingredients have the potential to inhibit cancer metastasis. This study aimed to investigate the cancer metastasis inhibitory effect of Dichroae Radix using network pharmacological analysis. Methods : The active compounds of Dichroae Radix have been identified using Traditional Chinese Medicine System Pharmacology Database and Analysis Platform. The UniProt database was used to collect each of information of all target proteins associated with the active compounds. To find the bio-metabolic processes associated with each target, the DAVID6.8 Gene Functional classifier tool was used. Compound-Target and Target-Pathway networks were analyzed via Cytoscape 3.40. Results : In total, 25 active compounds and their 62 non-redundant targets were selected through the TCMSP database and analysis platform. The target genes underwent gene ontology and pathway enrichment analysis. The gene list applied to the gene ontology analysis revealed associations with various biological processes, including signal transduction, chemical synaptic transmission, G-protein-coupled receptor signaling pathways, response to xenobiotic stimulus, and response to drugs, among others. A total of eleven genes, including HSP90AB1, CALM1, F2, AR, PAKACA, PTGS2, NOS2, RXRA, ESR1, ESR2, and NCOA1, were found to be associated with biological pathways related to cancer metastasis. Furthermore, nineteen of the active compounds from Dichroae Radix were confirmed to interact with these genes. Conclusions : The results provide valuable insights into the mechanism of action and molecular targets of Dichroae Radix. Notably, Berberine, the main active ingredient of Dichroae Radix, plays a significant role in degrading AR proteins in advanced prostate cancer. Further studies and validations can provide crucial data to advance cancer metastasis prevention and treatment strategies.

• Journal of Biomedical Engineering Research
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• v.36 no.3
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• pp.55-60
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• 2015

An effective image retrieval system is required as the amount of medical imaging data is increasing recently. Authors reviewed the recent development of text-based medical image retrieval including the use of controlled vocabularies - RadLex (Radiology Lexicon), FMA (Foundational Model of Anatomy), etc - natural language processing, semantic ontology, and image annotation and markup.

• Journal of Korean Medical classics
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• v.25 no.4
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• pp.105-113
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• 2012

Objectives : Acquiring information from symptoms is one of the important method to gain clinically available information in korean medicine. Therefore, up to now, study of symptom terms was frequently implemented in promotion of various information project. In data extraction methods using symptom information from DB, information search using synonym and method using ontology is studied and utilized. However, considering concept of symptom has essential information of appeared body area and phenomenon we think that extending synonym and ontology relationship in symptom terms can be useful for search and set to this study. Methods : We collect terms relevant to human body area and structure described in Donguibogam. Synonymous relationship between collected terms is organized. Relationship between collected terms is build to human-body-knowledge table which has form of Concept+Relation+Concept. Type of relationship is limited on a range of expressing content about parts of human body. Result & Conclusion : Search condition is generated automatically using relationship of the upper area in knowledge table contents. Information of next and previous acupuncture point, upper and lower acupuncture point, left and right acupuncture point can be searched using information of acupuncture point location, order, relative position in area, direction in knowledge table contents.

• Journal of Korean Medical classics
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• v.32 no.1
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• pp.133-143
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• 2019

Objectives : In this study, we analyze the medical significance of feces symptoms so that the daily records of the feces of individuals can be not only used as a measure of individual health monitoring in daily life, but also more actively connected to the medical treatment of the Korean Medicine (KM). Methods : Categories and clinically significant attributes for symptoms of Urination and defecation in the KM ontology DB are determined, and connected to KM related dialectical indicators by experts' common criteria including Viscera and Bowels [臟腑], eight principles [八綱], Qi Blood fluid and humor phlegm-retained fluid static blood [氣血津液痰飮瘀血], six excesses [六淫]. Results : The analysis of the symptoms of feces in the Korea Medicine ontology shows that the symptoms of stool in categories of 'stool stiffness', 'blood swelling', 'discomfort' are highly ranked among the overall clinical symptom categories. In the case of urine symptoms, symptoms corresponding to 'urine color,' 'urine discomfort,' and 'urine volume' are the top rankers among other total clinical symptoms. In the case of stool, the relationship between the symptom of stool and the categories of spleen, stomach, and colon is increased as the weighted symptom is considered. The relationship between the symptom of urine and the categories of the small intestine and the bladder is increased in the same way. Conclusions : This study could help better utilize the personal generated health records of feces in clinical practice of Korean Medicine.

• Journal of Korean Medical classics
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• v.36 no.3
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• pp.55-87
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• 2023

Objectives : To examine changes in Korean Medicine during Japanese occupation through major Joseoneo dictionaries. Methods : Based on the Keun Sajeon, published in 1957 by the Korean Language Society, the most recently published among the major dictionaries under Japanese occupation, key Korean Medical terminology in the Joseoneo Sajeon, published in 1920 by the governor-general of Joseon, and the Joseoneo Sajeon, published in 1938 by Mun Seyeong were analyzed. The differences among the dictionaries provided insight into the situation which Korean Medicine was in. Results : 1) There was a lack of consistency among Korean Medical terminology. 2) Changes in medical policies and legislation were reflected in the Korean Medical terminology without much delay. 3) Korean Medicine was distinguished as a separate category in the Keun Sajeon for the first time. 4) With the exception of Korean Medicine specific terminology, most were explained using 'modern' concepts and ontology. Conclusions : Modernization lead by the Japanese splintered many areas of Joseon society, and Korean Medicine was no exception. This transition period as reflected in the terminology within the Joseoneo dictionaries show that Korean Medicine went through a process of regulation by changes in medical policies and legislation, while new, modern studies brought in by the Japanese started replacing language and ontology of pre-occupation Joseon. A look into Korean Medicine during Japanese occupation through Joseoneo dictionaries allows us to examine the connection between Korean Medicine and the more broader historical context in which it was situated.