• The Journal of Korean Medicine
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• v.31 no.3
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• pp.47-54
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• 2010

Objective: To derive information on the efficacy of Sam-chul-kun-bi-tang (SKT), by evaluating its anti-inflammatory effect. SKT is a widely-used herbal formula in traditional Korean medicine. In man y studies, plant-derived anti-inflammatory efficacies have been investigated for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory effects of SKT extract on LPS-stimulated RAW 264.7 cells. Methods: The production of nitric oxide (NO), prostaglandin $(PG)E_2$, tumor necrosis factor (TNF)-$\alpha$ and interleukin (IL)-6 were examined in a macrophage cell line, RAW 264.7 cells, in the presence of SKT. RAW 264.7 cells were incubated with LPS 1 ${\mu}g/mL$ and SKT for 18 hrs. The anti-inflammatory activity of SKT was investigated by carrageenan-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenan-induced paw edema in rats. Results: SKT showed inhibitory effect on $PGE_2$, TNF-$\alpha$ and IL-6 in LPS-stimulated RAW 264.7 cells. But SKT was not inhibitory effect on NO by LPS-stimulated RAW 264.7 cells. Administration of SKT (1 g/kg) also showed a reduction in carrageenan-induced paw edema on rats. Conclusion: These results suggest that SKT has anti-inflammatory activities in both in vitro and in vivo models.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.449-455
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• 2022

The rapid rise in the application of novel treatment techniques, such as intensity-modulated radiotherapy (IMRT), motivated us to survey the status of Korea's radiation safety management and the shielding designs of facilities employing medical linear accelerators (LINACs). To this end, a questionnaire was used to collect information on LINAC facilities and treatments, workload, shielding design, shielding management, and path of obtaining shielding information. Out of 100 domestic institutions, 52 responded to the survey. Approximately 70% of the institutions utilized IMRT for more than 60% of their cases, and an IMRT factor of 5 was adopted by 75% of these institutions. Over 80% of the institutions accounted for the applied time-averaged dose rate per week and instantaneous dose equivalent rates in their shielding designs. Approximately 45% of the institutions obtained important shielding information via a radiation shielding design company and the NCRP-151 report. Overall, most facilities were shown to follow the standards recommended by the relevant international agencies. However, the requirement to establish standardized shielding design information and clarify ambiguous paths for information acquisition was also highlighted. Therefore, the study's results can be used as a foundation for establishing a safety control system and for creating adequate shielding designs.

• Herbal Formula Science
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• v.27 no.3
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• pp.213-221
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• 2019

Objectives : The purpose of this study is to confirm the efficacy and safety of the treatment of gastritis with 'Hwangryunhaedok-tang'. Methods : Total 20 people, between 19 and 65 years old, will be recruited to participate in a comparative clinical trial. All subjects will take 2 capsules of Hwangryunhaedok-tang (Redoxin Cap.), 3 times a day, 30 minutes after meals, for 8 weeks. Outcomes will be measured at the baseline, 4th week, and 8th week. Primary outcomes is the improvement rates of gastritis symptoms, such as heartburn, nausea/vomiting, abdominal bloating, anorexia, heartburn, and trim. Results : This trial was approved by institutional review board of Pusan National University Korean Medicine Hospital (registry number: 2018011), and registered in Clinical Research information Service, one of WHO. Recruitment opened in April 2019 and is supposed to be completed by December 2019. Conclusions : This trial will provide clinical information to determine the efficacy and safety of treatment of gastritis with 'Hwangryunhaedok-tang'.

• Journal of Biomedical Engineering Research
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• v.23 no.6
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• pp.431-436
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• 2002

The purpose of this study was to develop an integration protocol of Nuclear Medicine image with a commercial PACS. Two independent local networks. PACS network and Nuclear Medicine network, were connected using a Nuclear Medicine DICOM gateway A DICOM converter Program was developed to convert Interfile 3.3. which is used in nuclear medicine scanners in our hospital. to DICOM 3.0. The Program converts Interfile format images to those of DICOM format and also transfers converted DICOM files to PACS DICOM gateway. PACS DICOM gateway compares and matches the DICOM image information with patient information in Hospital Information System and then saves to PACS database. The transfer protocol was designed to be able to transfer Interfile. screen dumped file. and also scanned file. We successfully transferred Nuclear Medicine images to PACS. Images transferred by Interfile transfer protocol could be further processed using various tools in PACS. The graphs, numerical information and comments could be conveniently transferred by screen dumped file. The image in a hard copy can be transferred after scanning using an ordinary scanner. The developed protocol can easily transfer Nuclear Medicine images to PACS in various forms with low cost.

• Journal of Korean Traditional Oncology
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• v.12 no.1
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• pp.37-65
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• 2007

The Society for Integrative Oncology (SIO) is an international organization established to encourage scientific evaluation, dissemination of evidence-based information, and appropriate clinical integration of complementary therapies (http://www.Integrativeonc.org.). Practice Guidelines were developed by the authors listed below and by the Executive Committee of the Society for Integrative Oncology, which approved this document. Guidelines are a work in progress; they will be updated as needed and are available on the SIO Web site as well: www.IntegrativeOnc.org.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.4
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• pp.543-552
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• 2010

The objectives of this study are to examine the current status and problems of herb-drug interaction (HDI) information and information database in Korea and suggest the better way to establish useful HDI database. We collected HDI studies that published in Korea and analyzed according to objective, methods, selection criteria of herbs, number of study, correlation between study subject and frequently used herbal medicine (HM). Then we selected representative HM database on the internet made by Korea Food and Drug Administration (KFDA) among the several databases and analyzed its contents related to HDI. Several HDI studies were carried out from laboratory based research to clinical trials and HM databases have been developed for providing information about different aspects of traditional Korean medicine. But the information of HDI and information database are still far from practical applications because there are no coherence to select study subjects and methods among researchers. So, it is necessary to build up HDI database led by the government for providing systematic HDI information. HDI information database is expected to be able to provide useful evidence for health professionals in prescription and consultation to reduce the chance of adverse effects and improve the quality of medical care.

• Clinical and Experimental Pediatrics
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• v.64 no.5
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• pp.247-250
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• 2021

• The Korea Journal of Herbology
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• v.31 no.4
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• pp.93-100
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• 2016

Objectives : The internet is the most common method to investigate information. It is showed that 75.2% of Internet users of 20s had health information search experience. So this study is aim to understanding of interest of public about the herbal medicine using internet search query volume data.Methods : The Naver that is the top internet portal web service of the Republic of Korea has provided an Internet search query volume data from January 2007 to the current through the Naver data lab (http://datalab.naver.com) service. We have collected search query volume data which was provided by the Naver in 606 herbal medicine names and sorted the data by peak and total search volume.Results : The most frequently searched herbal medicines which has less bias and sorted by peak search volume is 'wasong (와송)'. And the most frequently searched herbal medicines which has less bias and sorted by total search volume is 'hasuo (하수오)'.Conclustions : This study is showed that the rank of interest of public about herbal medicines. Among the above herbal medicines, some herbal medicines had supply issue. And there are some other herbal medicines that had very little demand in Korean medicine market, but highly interested public. So it is necessary to monitor for these herbal medicines which is highly interested of the public. Furthermore if the reliability of the data obtained on the basis of these studies, it is possible to be utilizing herbal medicine monitoring service.

• The Journal of Korean Medicine
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• v.33 no.1
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• pp.52-67
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• 2012

Objectives: The purpose of this study was to evaluate the effects and develop the contents of a children's care program with traditional Korean medicine in a public health center. Methods: Data were collected from 28 parents who participated in a children care program with traditional Korean medicine. The program was started in June of 2011 in Gangjin-Gun public health center and finished in September of the same year. The questionnaires to measure effect and satisfaction with the program were composed of demographic items, family information, Psychological Well-Being Scale (PWBS), Parenting Stress Index (PSI), children health improvement checklist, etc. The questionnaires were executed before and after the program. Results: The PWBS scores increased (4.00, 3.66) and PSI scores decreased (-7.30. -5.95) significantly after the program. The satisfaction with the program was 100%, and 94% in the two groups, and treatment and lecture were mentioned as the best aspects of the program. Eating habits, sleep conditions, and activity also improved after the program. Conclusions: From these results, the children care program with traditional Korean medicine is worthy for improving children's health condition and reducing their parents' stress.

• The Korea Journal of Herbology
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• v.34 no.6
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• pp.63-70
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• 2019

Objective : Arnebiae Radix, the roots of Arnebia euchroma (Royle) Johnst. or A. guttata Bunge, is a well-known traditional herbal medicine in East Asia. In the Korean Pharmacopoeia, three authentic species, including two Arnebia and Lithospermum erythrorhizon Sieb. et Zucc. have recognized as a Lithospermi Radix. But, the morphological and taxonomic information of two authentic Arnebia species lacks date since their distribution and difficulty of accessing the natural habitats. Methods : A full description of the external morphological characteristics of vegetative and reproductive organs in the original plants was carried out using digital calipers and stereoscope. For providing their taxonomic and nomenclatural synonyms, we reviewed various plant checklists and taxonomic literature. Results : This study provides taxonomic information of A. euchroma and A. guttata based on a morphological examination of authentic plant individuals and field observations. Detailed descriptions of the two Arnebia species, major quantitative and qualitative characteristics, nomenclatural reviews, distribution maps, and lists of voucher specimens examined are provided. The shape of leaves, root length, stem number, calyx length and pubescence as well as corolla color were useful characteristics for identification. Moreover, we confirmed that A. euchroma and A. guttata are clearly heterostylous species. Conclusion : Our research provides valuable basic information that could be used as quality control for distinguishing between Arnebiae Radix and its adulterants. These results will help in the understanding of authentic plants and also provide the verified materials and voucher information.