• 한국미생물·생명공학회지
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• 제36권3호
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• pp.195-200
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• 2008

호이초는 한국, 일본, 중국 및 러시아에서 자생하는 범의 귀과의 다년생풀로, 민간에서는 주로 폐렴, 동상, 피부 염증 및 미생물감염 치료에 사용하여 왔다. 국내에서는 주로 관상용으로 재배되고 있어, 현재까지 재배관련 연구를 제외하고 생리활성 및 성분에 대한 연구는 전무한 상태이다. 본 연구에서는 호이초의 생리활성 평가를 위해 호이초 지상부의 생즙 및 메탄을 추출물을 조제하며 각각 항균, 항혈전 및 항산화 활성을 평가하였다. 지상부 생즙의 경우 Proteus vulgaris, Escherichia coli O157:H7 및 Candida albicans에 대해 항균효과가 인정되었고, 항산화 활성은 미약하였다. 반면 메탄올 추출물의 경우 염증 피부에서 분리한 세균, 일부세균 및 C. albicans에 대해 항균력을 나타내었으며, 강력한 항산화 활성을 나타내었다($IC_{50}$ of $37.5{\mu}g/mL$). 생즙 및 추출물 모두 1.5 mg/mL 농도에서 항혈전 활성은 나타나지 않았다. 메탄올 추출물 및 이의 순차적 유기용매 분획물의 항산화 활성 평가 결과, ethylacetate 및 butanol 분획에서 6.9 및 $7.8{\mu}g/mL$의 $IC_{50}$를 나타내어, vitamin C 및 BHT에 필적할 만한 강력한 항산화 활성을 확인하였다. 각 시료의 성분 분석 결과, 각 분획의 항산화 활성물질은 다양하며, ethylacetate 분획의 경우 항산화물질은 폴리페놀 배당체로 추측된다. 본 연구결과는 국내 자생 호이초가 항산화 식물자원으로 유용하게 개발될 수 있음을 제시하고 있다.

• 한국병원경영학회지
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• 제13권1호
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• pp.42-64
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• 2008

This study was conducted to evaluate the quality in medical records by analyzing its completeness through setting up the level of record on the patient's past history and through examining the actual medial records. Targeting the information on the patient's past history in interns' records, residents' records and nurses' records toward 403 inpatients who were admitted first in 2004 at an university hospital due to stomach cancer. We analyzed whether the charts were recorded or not, recording level, the satisfaction with the expectant level of the records in the hospital targeted for a research and the level of agreement. The results were as follows; first, as for the rate of recording those each items, they were high in the chief complaint & present illness and the past illness history. Depending on the group of recorders, the recording rate showed big difference by items. Second, as a result of measuring the level after dividing the recording level of items for the patient's past history from Level 1 to Level 4 by each item, the admission history, the past illness history, and the family history were about Level 3, and the smoking history, the medication history, the chief complaint & present illness, the drinking history and allergy were about Level 2. In the admission department, it was excellent in the interns' records for the medical department. Third, as a result of its satisfactory level by comparing the expect level of a record and the actual record by item in information on the patient's past history, which was expected by the medical-record committee members of the hospital targeted for a study. And forth, we analyzed the level of agreement with Kappa score in the level of 'Yes' or 'None' related to the corresponding matter in Level 1, in terms of information on the past history in the intern's record, the resident's record, and the nurse's record. The level of agreement in the resident's record & the nurse's record, and in the intern's record & the resident's record was from "excellent" to "a little good". There were differences in the level of completeness and in reliability for the information on the past history by the recorder group or by the admission department. The encounter process that was performed by the admission department or the recorder group, indicated the result that was directly reflected on the quality of medical records, thus it was required further study about the medical record documentation process and quality of care. The items that showed the high recording rate quantitatively were rather low, consequently we'd should develop the tool for the qualitative inspection and evaluate the medical records further. And the items were needed to be detailed in the record level were rather low, and hence there needed to be a documentation guideline and education by the clinical departments.

• 대한방사선기술학회지:방사선기술과학
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• 제35권3호
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• pp.211-218
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• 2012

부산광역시내 일개 대학병원의 영상의학과를 대상으로 환자와 접촉이 빈번한 검사장비의 세균오염도를 파악하고자 연구를 실시하였다. 입원환자 검사실의 소독 실시 전에는 MRSA, VRE, Acinetobacter baumannii, Candida albicans, Enterococcus sp.가 검출되었다. 소독 후에는 균이 완전히 사멸되었다. 검사 시간이 늘어남에 따라 검출되는 균이 많아졌으며 7시간 후에는 Bacillus sp.(GPR), CNS, Acinetobacter baumannii, Enterococcus sp.가 검출되었다. 감염환자 검사 후에는 Bacillus sp.(GPR), VRE, Enterococcus sp. CNS, Micrococcus sp.가 검출되었고 방사선사 손에서는 CNS, Enterococcus sp.와 Escherichia coli, Enterobacter sp.가 검출되었다. 각 검사실별로는 앞서 검출되었던 균종들과 비슷하였으나 이동검사장비의 손잡이와 대기실 의자에서 Pseudomonas aeruginosa가 검출되었다. 따라서 감염의 전파를 방지하기 위해서는 환자와 접촉이 빈번한 검사장비의 정기적인 소독과 감염환자 검사 후에는 즉시 소독을 실시하는 것이 가장 중요하며 철저한 손 씻기 수행과 영상의학과 특성에 맞는 감염교육과 관리를 통해 감염 예방을 체계적으로 할 수 있도록 해야 한다고 생각한다.

• 한국항해항만학회지
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• 제39권3호
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• pp.193-198
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• 2015

이 연구는 선내의료 및 선원 건강관리 여건 개선 방안을 마련하기 위하여 선원 건강관리 정책에 영향을 미치는 정부를 비롯한 선원 유관단체 종사자 139명을 대상으로 선원들의 건강과 질병관리에 대한 보건의료실태에 대한 인식도 조사를 실시하였다. 조사결과 선원들의 건강관리여건(p<0.01)과 건강관리 능력(p<0.01), 현행의 무선응급의료 정책(p<0.01), 선내 의료함 및 의료장비의 도움(p<0.05) 및 선박 의료관리자 제도에 대해 유관기관 간에 인식도 차이는 있었으나 대체적으로 부정적인 응답률이 높았으며, 선원 건강관리를 위한 선내의료 지원제도 개선을 위해서는 간이 건강측정장비 비치, 정기적 건강검진 강화, 원격의료 및 건강관리를 위한 선원건강증진센터의 설치(p<0.01)가 시급히 필요하다고 조사되었다.

• Parasites, Hosts and Diseases
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• 제22권1호
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• pp.109-115
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• 1984

대구시민들에 있어서 장내 기생광충류의 최근 감염상을 알아보기 위해 1983연 3월부터 9월까지 대구시내 5개동(남구 봉덕동, 북구 노원동, 서구 비산동, 동구 신암동 및 수성구 수성동)주민를 조사 대상으로 선정하여 formalinether 집란법 및 scotch-tape 항문주위도말법으로 광충류 충란 검사를 실시하였다. 총 피검자 1,697명중 장내접충류 감염률은 27.9%이었으며, 이중 편충이 13.2%로 가장 높았고, 그 다음은 7.0%를 나타내는 요충이었으며, 구충은 0.:1로 가장 낮았다. 성별 감염률에 있어서 남자의 경우 간흡충, 요꼬가와흡충, 조충등은 여자에 비해서 그 율이 다소 높았으나, 편충의 경우에는 양자간에 유의적 차를 인정할 수 없었다. 연령군별 감염률에 있어서는 편충은 20∼29세군에서 남자 17.5%. 여자 17.6%로 가장 높았으며, 0∼9세군에서는 남자 5.5%, 여자 9.6%로 가장 낮았다. 간흡충은 30∼39세군에서 가장 높았으며 요꼬가와흡충도 간흡충과 비슷한 양상을 나타내었다. 혼합기생상에 있어서는 1종기생이 가장 많았고 다음은 2종의 중복기생이었으며, 3종의 혼합기생은 매우 적었다. 이상의 성적으로 미루어 보아 대구직할시 주민들에서의 장내 기생 윤충류 감염은 아직도 고율임을 알 수 있었다.

• Parasites, Hosts and Diseases
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• 제28권4호
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• pp.213-220
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• 1990

형산강 일대는 과거에 간흠충의 농후유행지로 알려진 지역으로, 이 강을 끼고 있는 포항 및 영일 일대 공업지역의 근로자를 대상으로 하여 최근에 간흠충 감염 여부를 검사하고 간흡충 감염과 관련된 사항에 관하여 설문조사를 시행하였다. 그 결과를 요약하면 다음과 같다. 1) 총 3,180 명을 대상으로 간흡충 항원을 이용하여 피내반응검사를 실시하였는데 26.2%인 834명이 양성이었다. 이들 양성자 중에서 598명을 검변하여 129명 (21.6%)의 간흡충란 양성자를 검출하였다. 그 이외에 편충 1.7%, 회충 0.3% 및 요꼬가와흡충 0.2%의 충란양성를을 얻었다. 2) 간흠충 감염자는 모두 20∼40대의 남자이었으며 띠감염 대조군에 띠해 유의하게 중학교 이하 지 학력자의 비율이 높았고, 형산강을 낀 포항시 및 영일군의 챙전 동(동)에 거주하는 사람의 띠율이 높았으며, 20년 이상 장기 거주자의 비율이 감염자 군에서 높았다. 약 20% 내외의 감띰자가 구충제를 점기 복음하였고, 간흡충 감염 여부에 관한 검사를 반은 적이 있고 기생충 감엄애 관한 교육을 받은 걱이 있다고 하였다. 또한 대부분의 조사 대상자가 기생충 관리에 대한 교육을 인하였다 3) 감염자 군에서 민물고기를 날로 먹는 습관을 가진 사람의 비율이 유의하게 많았으며 주로 등어, 입어 등을 소비하였다. 4) 감염자를 프라지관텐로 치료하고 1년 후에 검변한 결곽 치료자의 85.3%가 충란을 배출하지 않았다. 이상의 결과로 미루어 보면 형산강 일대에서 간흡충의 유행이 과거에 띠해 뚜렷하게 감소하였으나 아직도 많은 사람이 감염되어 있음을 확인할 수 있었다. 간흡충의 빠른 근절을 위해서는 올바른 진단과 치로 및 기생충에 관한 교육이 절실하게 요구된다.

• 분석과학
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• 제28권5호
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• pp.309-316
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• 2015

본 연구에서는 ICP-MS의 혈장 중 극미량의 납 분석법을 검증하기 위하여 Class 1,000 이내의 환경조건을 확보한 후 특이성, 일내 및 일간 정확도, 정밀도, 검정곡선 등을 확인하였다. 청정실의 부유 분진량을 측정한 결과, 0.3 µm 크기는 0.3~62개, 0.5 µm 크기는 0.0~28.3 개로 총 부유분진량이 최대 90.3개로 요구 환경에 부합하였다. 우태아 혈청 공시료로 조제한 시료의 MDL (Method detection limit)은 1.77 ng/L이고, LOQ (Limit of quantification)값은 5.55 ng/L 이었다. 검정곡선은 y=1.09×10⁻³ x+4.88×10⁻²이었고, 상관계수 r=0.9999이었다. 분석법 확립을 위한 특이성, 일내 및 일간 정확성, 정밀성, 그리고 검정곡선을 확인한 결과 50 ng/L 이상에서 분석법 확인 기준에 적합하였다. 이를 토대로 분석한 일반인의 혈장 중 납 농도 평균은 55.4 ng/L 이었으며, 현직 근로자는 440 ng/L 이었고, 퇴직 근로자는 132 ng/L 이었다.

• 한국의료질향상학회지
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• 제7권2호
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• pp.190-202
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• 2000

Background : The objectives of this study were to examine patients' satisfaction with the DRG based payment method and its association with their awareness of the method, to examine patient reported changes in doctors' caring attitude, level of their out-of-pocket payments, providers' acceptance of patients' request for additional services after the program, and to examine changes in service utilization recorded in medical records. Method : One hundred-four patients who had cesarean sections before and after the demonstration program at two hospitals located in Seoul participated in the study. Patients were surveyed before discharges when their charges were finalized. Their medical records were reviewed as well to collect data for service utilization during hospital stays. The association between patients' satisfaction with the payment method and their awareness of the method was analyzed by ${\chi}^2$-test, and the significance of changes in providers' acceptance of patients' request for additional services and service utilization after the program were examined by ${\chi}^2$-test and t-test, respectively. Results : A large proportion of patients did not know of the DRG based payment method at the time of survey and a significantly larger proportion of patients who came to the hospitals with the knowledge satisfied with the method. About the same proportion of patients reported improvement and deterioration in doctors' caring attitude compare to the previous hospitalizations and a similar result was found concerning out-of-pocket payments. Providers' acceptance of patients' request for medication, PCA and painless delivery decreased significantly after the program whereas the acceptance for additional hospital days and laboratory and radiology tests did not. Length of stay, the numbers of days on antibiotics and antianemic medication, and the number of blood tests decreased significantly after the program, however, decreases in the rate of antianemic medication and the number of urine analyses were not statistically significant. Re-operation, in-hospital death, and complications were not observed before and after the program. Conclusion : The study findings indicated a need for better patient education and publicity about the newly introduced payment method to improve their satisfaction with the system. Other study findings concerning service utilization and quality of care indicators were consistent with the government funded evaluation studies.

• Child Health Nursing Research
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• 제7권2호
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• pp.179-190
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• 2001

The purposes of the study were to develop an instrument for family value and to identify the relationships of family value, family hardiness, and family adaptation by appling the family value scale to family with cancer children. The study was conducted in three phases. 1) A survey was conducted from July 20 to August 20, 1999 and 18 items of general family value scale was modified from the data of 153 fathers and 164 mothers. 2) In-depth interviews were made with 29 parents of cancer children from April 20, 1998 to May 20, 1999 to develop family value scale with cancer children, and 12 statements were developed. 3) The final survey was conducted from July 18, 2000 to August 30, 2000 and the data from 309 parents of children who are diagnosed as cancer, 18 or less years of age, and treated either hospitalized or at the outpatient clinics were analyzed to identify the relationships of the concepts. The data analysis utilized SAS 6.12 and LISREL 8 for descriptive statistics, correlation, and Regression for path analysis. The study findings are as follows. The psychometric testing of general family value scale was Cronbach's alpha = 0.78. The reliability of the family value scale with cancer children showed the reliability as Cronbach's alpha = 0.73. Demographic characteristics showing significant correlations were cancer children's age, period of illness, period after completing treatment, mother's age, mother's education level, monthly income, payment type, confidence with health professional, and severity of children's illness. The correlation coefficients among major variables showed that family stressor was positively related with family strains(r=0.33, p<.001), and negatively related with family hardiness(r=-0.21, p<.001). Family strains was negatively related with family hardiness(r= -0.41, p<.001) and family adaptation(r=-0.46, p<.001). Correlations of family hardiness was positive with family value with cancer children(r=-0.31, p<.001), and negative with general family value(r=-0.16, p<.01). Family hardiness was positively related with family adaptation(r=0.35, p<.001). The causal relationship between study variables showed that family strains predicts general family value(γ=0.12, t=2.02), family value with cancer children predicts family hardiness(γ=0.31, t=6.30), family strains predicts family hardiness(γ=-0.40, t=-7.70), family value with cancer children predicts family adaptation(γ=-0.23, t=-4.11), and family hardiness predicts family adaptation(γ=0.43, t=7.78).

• Child Health Nursing Research
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• 제6권2호
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• pp.144-157
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• 2000

This study was done to understand nonpharmacologic pain management for pediateric patients and nurses' knowledge and attitudes toward it. The aim of this study was that which method did the patient's use according to the nurses' age, and how did they effectively use these methods in their field. The subjects of this study were 77 nurses working in the Pediatric unit in the Kyung Medical Center from September 2 to 15, 1999 using questionnaire form. The results of this study were as follows : 1. We divided the subjects into four groups : Younger than one year old, 1-6 years, 6-12 years, 12-18 years group. In the group younger one year old, most of the nurses participating in this study used speaking in soft quiet tones, supportive touch, toys, pacifiers. In the group of 1-6 years, they used speaking in soft quiet tones, toys, distracting attention, story talking, and visual stimulus. In the group of 6-12 years. they used pop-up books, providing information, cold therapy, speaking in soft quiet tones, supportive touch. In the group of 12-19 years, most of them used providing information, controling respiration and supportive touch. 2. The effective nursing intervention used in their field are speaking in soft quiet tones, pacifiers and nesting with blanket in the group of younger than one year old. Un the group of 1-6 years old, speaking in soft quiet tones, toys, and supportive touch were effective method in the control of nonp-harmacologic pain management. In the group of 6-12 years old, story talking, supportive touch, and speaking in soft quiet tones were effective method and in the group of 12-18 years old, providing information, cold therapy and supportive touch were effectively used to control nonpharmacologic pain management. 3. To compare the general characteristics and non-pharmacologic pain nursing intervention, in the group of younger than one year, touching stimuli is widely used. In the groups of 1-6, and 6-12 years old, visual and audio method were widely used. In the group of 12-18 years old, sensitive intervention were used as well as education, information and guided imagery. In conclusion, there was no significant difference in nurses' demographic characteristics, child's age and nonpharmacologic pain management. There was significant difference only in the nurses working area, that is nurses working in the surgical department used more audio-visual-tactile pain management methods than medical department.