• Journal of Environmental Health Sciences
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• 제40권1호
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• pp.1-9
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• 2014

Objectives: The purpose of this review is to suggest future directions for the Korean Environmental Health Survey (KoNEHS) in terms of an environmental health monitoring system and recent environmental health issues in Korea. Methods: The national scale biomonitoring program and environmental health researches which conducted by Ministry of Environment was reviewed for this study. The scope, contents and utilization of results of KoNEHS as a biomonitoring program and other basic function for environmental health monitoring was analyzed. Results: Biomonitoring survey was conducted for basic functions, such as evaluating exposure levels of environmental chemicals and analyzing exposure factors. In order to expand the basic purposes of KoNEHS, the biomonitoring function should be strengthened by enlarging the range of chemicals analyzed and including all age groups in the biomonitoring and health status monitoring functions by using official health-care and mortality data. Exposure factors such as time-activity patterns and micro-environmental pollution levels were studied. The data from the environmental health study were established into a standardized database system for supporting environmental health policy. A definition and concept of environmental health services should be established. Conclusion: To achieve the aims of environmental health, changes in environmental health status and related factors must be observed and predicted reflecting real conditions. In this regard, improving the methodology and system through diverse approaches is necessary for KoNEHS.

• Journal of Wetlands Research
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• 제10권1호
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• pp.11-20
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• 2008

In this study the estimation method for stream hydraulic characteristics which is served as the input data set for running QualKo water quality model is investigated. The conventional approach for estimating such hydraulic parameters is to use the data set from the last cross section in each reach. However, it is shown that in order to represent correctly flow velocity profiles or the travel time in streams, hydraulic parameters of QualKo model should be estimated with all cross section data set within the corresponding reach. In addition, the unsuitable estimation of hydraulic parameters at some reaches has influence on the water quality predictions at the corresponding reaches, and the errors of water quality predictions are propagated toward the downstream without any error attenuation.

• Journal of Embryo Transfer
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• 제29권2호
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• pp.195-200
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• 2014

Endothelin 2 (EDN2) induces follicular rupture by constricting periovulatory follicles. In this study, it was investigated the mechanisms of EDN2 action on follicular rupture with respect of receptor using the conditionally granulosa cell specific EDN2 receptor type A (ETa) KO mice (gcETaKO; $ETa^{flox/-}{\cdot}Amhr2^{Cre}$). It was generated the gcETaKO mice by breeding with $ETa^{flox/-}$ mice after mono-alleic ETa knockout by $ZP3^{Cre}$ and $Amhr2^{Cre}$ mice. Fertility, ovulation and maturation rates of ovulated oocytes after super ovulation were investigated in the gcETaKO mice compared with wild-type mice ($ETa^{flox/flox}$ and $ETa^{flox/-}$) as a control group. In the gcETaKO mice, normal fertility after breeding with male mice was shown compared with wild-type mice. And, there was no significant differences in ovulation rates after super ovulation, however its maturation rates was lower than that of wild type mice. These findings show that EDN2 in follicular rupture for ovulation is related with an other ETa not in granulosa cells. Further studies are needed to investigate how EDN2 is acted in ovarian follicular rupture for ovulation.

• Korean Journal of Veterinary Research
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• 제45권4호
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• pp.517-525
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• 2005

This study was performed to evaluate using wild-type (WT) and $C{\times}32$ knockout (KO) mice if lack of cell to cell communication by connexin 32 gap junction enhances the benzene-induced hematotoxicity and hemopoietic tumor development. The WT and $C{\times}32$ KO mice were exposed to 300 ppm of benzene for 6 hours/day, 5 days/week for a total of 26 weeks by inhalation, and then sacrificed to evaluate the toxicities of hemopoietic organs or allowed to live out their life span to evaluate the hemopoietic tumor incidence. The significant increase and decrease of organ weight were respectively noted in spleen and thymus of both WT and $C{\times}32$ KO mice without significant difference between the genotypes. Histopathologically, benzene exposure for 26 weeks induced the morphological changes in hemopoietic organs, characterized by fat cell accumulation in the bone marrow and extramedullary hemopoiesis in the spleen. The fat cell accumulation was, compared with that of WT mice, considerably exacerbated in the $C{\times}32$ KO mice. However, no significant difference was observed in the changes of hematological values and bone marrow cellularity as well as in the onset and incidence of hemopoietic tumors between WT and $C{\times}32$ KO mice. In conclusion, this study indicated little significant role of the cellular communication by $C{\times}32$ gap junction in the action mechanism of benzene hematotoxicity and leukemogenicity.

• Proceedings of the Korean Information Science Society Conference
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• 한국정보과학회 2010년도 한국컴퓨터종합학술대회논문집 Vol.37 No.1(C)
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• pp.197-200
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• 2010

웹 기술이 발달함에 따라 공공기관 웹사이트는 단순한 행정기관의 홍보에서 벗어나 국민과 정부 간의 의사소통의 증거인 동시에 업무의 기록으로서 역할을 담당하고 있다. 따라서 공공기관의 웹사이트들은 공공기록물로 인식하고 보호해야 한다. 하지만 공공기관의 웹기록물 중 하나인 심층 웹기록물은 실시간으로 상이한 페이지를 동적으로 구성하기 때문에 기존의 보존방법과는 다른 수집 보존 활용 기술이 요구된다. 국가기록원은 이러한 특징을 가지고 있는 심층 웹기록물을 장기보존하기 위해서 심층 웹기록물 장기보존 포맷인 KoDeWeb을 연구하고 개발하였다. KoDeWeb은 전자기록물이기 때문에 전자기록물로서 진본성 및 무결성을 보장해야 한다. 본 연구에서는 KoDeWeb의 전자기록물로서의 진본성 및 무결성을 증명하기 위해 국제 전자기록물 표준인 OAIS 참조모델에 KoDeWeb을 맵핑시켰다. 나아가 OAIS표준을 따르고 있는 전자기록물 장기보존 시스템에 KoDeWeb을 사용함으로써, 정부 및 공공기관의 심층 웹기록물 생성 및 수집을 체계화하고, 또한 민간이 운영하는 웹의 심층 웹기록물 장기보존에 활용할 수 있다.

• Molecules and Cells
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• 제42권8호
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• pp.589-596
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• 2019

${\beta}Pix$ is a guanine nucleotide exchange factor for the Rho family small GTPases, Rac1 and Cdc42. It is known to regulate focal adhesion dynamics and cell migration. However, the in vivo role of ${\beta}Pix$ is currently not well understood. Here, we report the production and characterization of ${\beta}Pix$-KO mice. Loss of ${\beta}Pix$ results in embryonic lethality accompanied by abnormal developmental features, such as incomplete neural tube closure, impaired axial rotation, and failure of allantois-chorion fusion. We also generated ${\beta}Pix$-KO mouse embryonic fibroblasts (MEFs) to examine ${\beta}Pix$ function in mouse fibroblasts. ${\beta}Pix$-KO MEFs exhibit decreased Rac1 activity, and defects in cell spreading and platelet-derived growth factor (PDGF)-induced ruffle formation and chemotaxis. The average size of focal adhesions is increased in ${\beta}Pix$-KO MEFs. Interestingly, ${\beta}Pix$-KO MEFs showed increased motility in random migration and rapid wound healing with elevated levels of MLC2 phosphorylation. Taken together, our data demonstrate that ${\beta}Pix$ plays essential roles in early embryonic development, cell spreading, and cell migration in fibroblasts.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• 제22권4호
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• pp.23-28
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• 2022

Recently smart device(such as smart phone and tablet PC) become a role as an information gateway, using of the web news by multiple users from the web portal has been more important things. However, the quantity of creating web news on the web makes hard to catch the information which the user wants and confuse the users cause of the similar and repeated contents. In this paper, we propose the news recommend system using the document summarization based on KoBART which gives the selected news to users from the candidate news on the news portal. As a result, our proposed system shows higher performance and recommending the news efficiently by pre-training and fine-tuning the KoBART using collected news data.

• ETRI Journal
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• 제45권1호
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• pp.18-27
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• 2023

We present an English-Korean speech translation corpus, named EnKoST-C. End-to-end model training for speech translation tasks often suffers from a lack of parallel data, such as speech data in the source language and equivalent text data in the target language. Most available public speech translation corpora were developed for European languages, and there is currently no public corpus for English-Korean end-to-end speech translation. Thus, we created an EnKoST-C centered on TED Talks. In this process, we enhance the sentence alignment approach using the subtitle time information and bilingual sentence embedding information. As a result, we built a 559-h English-Korean speech translation corpus. The proposed sentence alignment approach showed excellent performance of 0.96 f-measure score. We also show the baseline performance of an English-Korean speech translation model trained with EnKoST-C. The EnKoST-C is freely available on a Korean government open data hub site.

• Annual Conference on Human and Language Technology
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• 한국정보과학회언어공학연구회 2023년도 제35회 한글 및 한국어 정보처리 학술대회
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• pp.306-311
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• 2023

최근 생성형 언어모델에 명령어 튜닝을 적용하여 사람의 명령을잘이해하고, 대답의 성능을 향상시키는 연구가 활발히 수행되고 있으며, 이 과정에서 다양한 명령어 튜닝 데이터셋이 등장하고 있다. 하지만 많은 데이터셋들 중에서 어떤 것을 선택해서 활용하지가 불분명하기 때문에, 현존하는 연구들에서는 단순히 데이터셋을 모두 활용하는 방식으로 명령어 튜닝이 진행되고 있다. 하지만 최근 연구들에서 고품질의 적은 데이터셋으로도 명령어 튜닝을 하기에 충분하다는 결과들이 보고되고 있는 만큼, 많은 명령어 데이터셋에서 고품질의 명령어를 선별할 필요성이 커지고 있다. 이에 따라 본 논문에서는 한국어 데이터셋에서도 명령어 튜닝 데이터셋의 품질을 향상시키기 위해, 기존의 데이터셋들에서 데이터를 큐레이션하여 확보된 적은 양의 고품질의 명령어 데이터셋인 KoQuality를 제안한다. 또한 KoQuality를 활용하여 한국어 언어모델에 명령어 튜닝을 진행하였으며, 이를 통해 자연어 이해 성능을 높일 수 있음을 보인다. 특히 제로샷 상황에서 KoBEST 벤치마크에서 기존의 모델들보다 높은 성능 향상을 보였다.

• Annual Conference of KIPS
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• 한국정보처리학회 2023년도 추계학술발표대회
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• pp.1014-1015
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• 2023

많은 장애아 부모들은 양육에 대한 스트레스, 미래에 대한 걱정으로 심리적으로 상당한 중압감을 느낀다. 이에 비해 매년 증가하는 장애인 수에 비해 장애아 부모 및 가족의 심리적·정신적 문제를 해결하기 위한 프로그램이 부족하다.[1] 이를 해결하고자 본 논문에서는 감정분석 소통 플랫폼을 제안한다. 제안하는 플랫폼은 KoBERT 모델을 fine-tunning 하여 사용자의 일기 속 감정을 분석하여 장애아를 둔 부모 및 가족 간의 소통을 돕는다. 성능평가는 제안하는 플랫폼의 주요 기능인 KoBERT 기반 감정분석의 성능을 확인하기위해 텍스트 분류 모델로 널리 사용되고 있는 LSTM, Bi-LSTM, GRU 모델 별 성능지표들과 비교 분석한다. 성능 평가결과 KoBERT 의 정확도가 다른 분류군의 정확도보다 평균 31.4% 높은 성능을 보였고, 이 외의 지표에서도 비교적 높은 성능을 기록했다.