• Mass Spectrometry Letters
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• 제5권4호
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• pp.115-119
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• 2014

The Brazil nut (Bertholletia excelsa - Lecythidaceae) is considered a product with high economic value, being a food widely appreciated for its nutritional qualities. Although previous studies have reported the biochemical composition of Brazil nut oil, the knowledge regarding the phospholipid composition exhibits a disagreement: the composition of fatty acids present in the structures of phospholipids is reported as being different from the composition of the free fatty acids present in the oil. In this work, solid phase extraction (SPE) was employed to provide a fast extraction of the phospholipids from Brazil nuts, in order to compare the phospholipid profile of the in nature nuts and their fatty acids precursor present in the oil. The major phospholipids were characterized by mass spectrometry approach. Their fragmentation pattern through direct infusion electrospray ionization ion-trap tandem mass spectrometry ($ESI-IT-MS^2$) proved to be useful to unequivocal characterization of these substances. High resolution (HR) experiments through ESI using a quadruple time of flight mass spectrometry (QTOF) system were performed to reinforce the identifications.

• 창의정보문화연구
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• 제5권2호
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• pp.145-156
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• 2019

본 연구에서는 명명된 실체 인식 기법에 기초한 정보 추출 모듈을 개발하고 평가하였다. 본 논문의 제시된 목적을 위해, 모듈은 사전 지식 없이 임의의 문서에서 우편 주소 정보를 추출하는 문제에 적용하도록 설계되었다. 정보 기술 실무의 관점에서, 우리의 접근방식은 유니그램 기반 키워드 매칭과 비교하여 일반화된 기법인 확률론적 n-gram(바이오그램 또는 트리그램) 방법이라고 말할 수 있다. 모델을 순차적으로 적용하지 않고 문장검출, 토큰화, POS 태그를 재귀적으로 적용하는 것이 우리의 접근법과 자연어 처리에 채택된 전통적인 방법 사이의 주요한 차이점이다. 이 논문에서는 약 2천 개의 문서를 포함한 시험 결과를 제시한다.

• Natural Product Sciences
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• 제29권2호
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• pp.83-90
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• 2023

To our knowledge, this is the first study aiming to optimize the extraction conditions of total phenolic compounds (TPC) and total flavonoids contents (TFC) from Argania spinosa leaves using Response Surface Methodology (RSM) with a Box-Behnken design (BBD). The optimal conditions obtained were 5% (w/v) solvent-to-solid ratio, 72.33% ethanol concentration, and 10h ours as an extraction time, which resulted in an extract with maximum TPC (131.63 mg GAE/g dw) and TFC (10.66 mg QE/g dw). Under the optimal extraction conditions, the antioxidant activity of the extracts of leaves of argan tree showed a moderate antiradical capacity of DPPH (IC₅₀ = 0,130 mg/mL) and ABTS (IC₅₀ = 0.198 mg/mL). However, the leaves of argan tree showed a very interesting reducing power of Iron (IC₅₀ = 0.448 mg/ml) which is similar to that of the ascorbic acid (IC₅₀ = 0.371 mg/mL).

• 대한의용생체공학회:의공학회지
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• 제29권4호
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• pp.329-336
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• 2008

Recently, causality analysis of source time series extracted from EEG or MEG signals is becoming of great importance in human brain mapping studies and noninvasive diagnosis of various brain diseases. Two approaches have been widely used for the analyses: one is independent component analysis (ICA), and the other is multiple signal classification (MUSIC). To the best of our knowledge, however, any comparison studies to reveal the difference of the two approaches have not been reported. In the present study, we compared the performance of the two different techniques, ICA and MUSIC, especially focusing on how accurately they can estimate and separate various brain electrical signals such as linear, nonlinear, and chaotic signals without a priori knowledge. Results of the realistic simulation studies, adopting directed transfer function (DTF) and Granger causality (GC) as measures of the accurate extraction of source time series, demonstrated that the MUSIC-based approach is more reliable than the ICA-based approach.

• Journal of Computing Science and Engineering
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• 제2권2호
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• pp.109-136
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• 2008

In this survey paper, we discuss biomedical ontologies and major text mining techniques applied to biomedicine and healthcare. Biomedical ontologies such as UMLS are currently being adopted in text mining approaches because they provide domain knowledge for text mining approaches. In addition, biomedical ontologies enable us to resolve many linguistic problems when text mining approaches handle biomedical literature. As the first example of text mining, document clustering is surveyed. Because a document set is normally multiple topic, text mining approaches use document clustering as a preprocessing step to group similar documents. Additionally, document clustering is able to inform the biomedical literature searches required for the practice of evidence-based medicine. We introduce Swanson's UnDiscovered Public Knowledge (UDPK) model to generate biomedical hypotheses from biomedical literature such as MEDLINE by discovering novel connections among logically-related biomedical concepts. Another important area of text mining is document classification. Document classification is a valuable tool for biomedical tasks that involve large amounts of text. We survey well-known classification techniques in biomedicine. As the last example of text mining in biomedicine and healthcare, we survey information extraction. Information extraction is the process of scanning text for information relevant to some interest, including extracting entities, relations, and events. We also address techniques and issues of evaluating text mining applications in biomedicine and healthcare.

• 한국정보통신학회논문지
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• 제9권7호
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• pp.1582-1587
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• 2005

본 논문은 정수장에서 사용하는 응집제의 종류를 결정하기 위한 시스템 개발에 관한 내용이다. 정수장은 여러 단위 처리장으로 구성되며, 불순물을 제거하기 위하여 혼화지에서 응집제를 주입하여 침전을 시킨다. 현재까지 응집제 결정을 위해 Jar-test를 이용하는데, 이 방법은 사람의 주관적인 판단에 의존하므로 실험 오차가 발생할 수 있다. 특히 정수장의 자동화를 위한 시스템 개발에서 가장 큰 걸림돌로 작용하고 있다. 본 논문은 이러한 문제점을 해결하기 위하여 로드맵에 기초한 데이터마이닝 기법을 이용하여 응집제를 선택할 수 있는 제어기를 개발하였다. 제어 규칙은 클러스터링 기법으로 도출하였는데, 군집의 초기 값과 개수는 통계적 지수 값을 사용하여 결정하였다.

• 한국컴퓨터정보학회논문지
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• 제5권2호
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• pp.14-21
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• 2000

이용자의 학술정보 데이터베이스의 기능을 보충하는 새로운 지식표현 패러다임으로 기술정보공간(ICPIS: Information Communication Papers Intelligent Surveyor)을 제안한다. 이것은 기술정보로부터 자동적으로 구축되어 그 중에서 이용자가 자유롭게 탐방 할 수 있는 정보 공간이다. 구축방법과 탐방기능을 명확히 하여 실 시스템을 구축, 평가하는 것이 연구의 목적이다. 이를 위해 ICPIS는 Keyword로 기술된 논문군을 입력하여 논문내용의 항목별 요약, 유사논문의 시각적 표시와 비교, 인과관계의 추출을 시작으로 논문의 요약정보, Survey정보를 사용자에게 제공한다. ICPIS에서 중심적 역할을 나타내는 것은 KP(Knowledge Piece)로 불리고, 이는 기술정보의 추출법과 구조화법을 일체화한 Domain지식의 패키지이다. ICPIS는 KP별로 기술된 Keyword에서 자연언어처리에 해당되는 기술정보를 논문 중에서 추출하여 KP에서 규정된 요약구조로 생성한다.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 2019년도 제31회 한글 및 한국어 정보처리 학술대회
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• pp.185-189
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• 2019

관계추출기의 학습을 위해서는 많은 학습 데이터가 필요한데, 사람이 모으게 되면 많은 비용이 필요하여 원격 지도 학습을 이용한 데이터 수집이 많은 연구에서 사용되고 있다. 원격 지도 학습은 지식베이스를 기반으로 학습 데이터를 자동으로 만들어 내는 방식이기에 비용이 거의 들지 않지만, 지식베이스의 질과 양에 영향을 받는다. 본 연구는 원격 지도 학습을 기본으로 관계추출기의 성능을 향상 시키고, 지식베이스를 확장하는 방안으로 반복학습을 제안한다. 실험을 적은 비용으로 빠르게 진행하기 위해 반복학습을 자동화 하는 시스템을 설계하여 실험을 하였고, 이 시스템으로 관계추출기의 성능이 향상 될 수 있는 가능성을 보였으며, 반복학습을 통한 지식베이스의 확장 방안을 제시한다.

• 한국시뮬레이션학회논문지
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• 제4권1호
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• pp.1-11
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• 1995

The model of a FMS (Flexible Manufacturing System) admits to a natural hierarchical decomposition of highly decoupled units with similar structure and control. The FMS fractal architecture model represents a hierarchical structure built from elements of a single basic design. A SES (System Entity Structure) is a structural knowledge representation scheme that contains knowledge of decomposition, taxonomy, and coupling relationships of a system necessary to direct model synthesis. A substructure of a SES is extracted for use as the skeleton for a model. This substructure is called pruned SES and the extraction operation of a pruned SES from a SES is called pruning (or pruning operation). This paper presents a pruning operation called recursive pruning. It is applied to SES for generating a model structure whose sub-structure contains copies if itself as in FMS fractal architecture. Another pruning operation called delay pruning is also presented. Combined with recursive pruning the delay pruningis a useful tool for representing and constructing complex systems.

• 산업경영시스템학회지
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• 제21권45호
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• pp.101-112
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• 1998

Data mining, which is also referred to as knowledge discovery in database, means a process of nontrivial extraction of implicit, previously unknown and potentially useful information (such as knowledge rules, constraints, regularities) from data in databases. The discovered knowledge can be applied to information management, decision making, and many other applications. In this paper, a new data mining problem, discovering sequential patterns, is proposed which is to find all sequential patterns using sampling method. Recognizing that the quantity of database is growing exponentially and transaction database is frequently updated, sampling method is a fast algorithm reducing time and cost while extracting the trend of customer behavior. This method analyzes the fraction of database but can in general lead to results of a very high degree of accuracy. The relaxation factor, as well as the sample size, can be properly adjusted so as to improve the result accuracy while minimizing the corresponding execution time. The superiority of the proposed algorithm will be shown through analyzing accuracy and efficiency by comparing with Apriori All algorithm.