• Tuberculosis and Respiratory Diseases
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• 제86권3호
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• pp.216-225
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• 2023

Background: Tuberculosis (TB)-related stigma has been well-documented. Since the emergence of the coronavirus disease 2019 (COVID-19), different organizations have been alerted to the fact that stigma could arise again. Due to stigma's negative effects, this qualitative study aimed to explore the stigma felt by patients by evaluating the following: COVID-19 stigma and its temporal progression through the pandemic; stigma perceived by different patients with TB before and during COVID-19 pandemic; and difference perceived by individuals who contracted both diseases. Methods: A semi-structured interview was developed according to the available literature on the theme. It was performed individually in 2022 upon receiving signed informed consent. Participants were recruited with a purposive sampling approach by searching medical records. Those who currently or previously had pulmonary TB and/or COVID-19 were included. Data were subjected to thematic analysis. Results: Nine patients were interviewed, including six (66.7%) females. The median age of patients was 51±14.7 years. Four participants (44.4%) had completed high school and four (44.4%) were never smokers. Three had both TB and COVID-19. Four only had TB and two only had COVID-19. Interviews identified eight main themes: knowledge and beliefs, with several misconceptions identified; attitudes towards the disease, varying from social support to exclusion; knowledge and education, assumed as of extreme importance; internalized stigma, with self-rejection; experienced stigma, with discrimination episodes; anticipated stigma, modifying actions for avoiding stigma; perceived stigma, with judgment by others prevailed; and temporal evolution of stigma. Conclusion: Individuals expressed strong stigma for both diseases. De-stigmatization of respiratory infectious diseases is crucial for limiting stigma's negative impact.

• ALGAE
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• 제38권4호
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• pp.253-264
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• 2023

The Ceramiales is the most diverse and species-rich group (2,669 spp.) of red algae, and it is widely distributed from tropical to polar oceans. Mitochondrial genomes (mitogenomes) and other genes have contributed to our knowledge regarding the classification and phylogeny of this diverse red algal group; however, the mitogenome architecture remains understudied. Here, we compared 42 mitogenomes, including 19 newly generated in this study, to expand our knowledge. The number of genes in mitogenome varied from 43 to 68 due to gene duplication. The mitogenome architecture was also variable, categorized into four types (A-D): type A = ancestral type with a basic composition; type B = those with inverse transpositions; type C = those with inverted duplications; and type D = those with both inversion and duplication. The palindromic and inverted repeats were consistently found in flanking regions of the rearrangement, especially near the cob and nad6 genes. The three rearranged mitogenome architectures (types B, C, D) are the first report of these in red algae. Phylogenetic analyses of 23 protein-coding genes supported the current familial classification of the Ceramiales, implying that the diversity of mitogenome architecture preceded the phylogenetic relationships. Our study suggests that palindromic and inverted repeats may drive mitogenome architectural variation.

• 지능정보연구
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• 제28권2호
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• pp.207-235
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• 2022

지식과 정보산업이 경제의 주축인 지식기반 사회에 있어 지식의 공유와 확산 및 체계적인 관리는 국가 경쟁력 향상뿐만 아니라 지속 가능한 사회 발전의 필수 전략으로 인식되고 있다. 정보기술과 경영의 융합이 다양한 방식으로 일어나고 있는 정보시스템(Information Systems: IS) 연구분야에서, 연구자들이 서로 협력하여 오래된 지식을 과학적 지식네트워크의 관점에서 새로운 지식으로 만들어 낼 때 비로소 지식의 진화가 일어난다. 특히, 인용과 공저, 키워드와 같은 네트워크 기반의 학제적 접목을 통해 해당 연구분야의 관심 주제와 적용된 방법론, 연구동향 등을 파악함으로써 새로운 통찰을 이끌어낼 수 있다. 선행연구에서는 연구주제와 방법론, 공동저자 등의 관계를 밝혀 해당 커뮤니티의 지식체계 구조와 연구동향을 파악하려는 다양한 시도가 있어 왔으나, 두 개 이상의 저널을 일부 기간으로 한정해서 비교한 연구가 대부분을 차지하였으며, IS 연구의 전 역사를 아우르면서 연구동향을 살펴본 연구는 부족한 실정이다. 이에 본 연구에서는 IS 연구분야에서 관련 지식을 넓히는 데 주도적인 역할을 수행하고 있는 MIS Quarterly (MISQ) 저널을 중심으로 창간호(1977년)부터 최근(2022년 1분기)까지 게재된 모든 논문으로부터 (1) 키워드를 추출하고, (2) 추출된 키워드를 연구주제와 방법론, 이론 등으로 각각 구분한 후, (3) 토픽모델링과 키워드 네트워크 분석을 활용하여 IS 연구분야의 태동부터 현재까지의 변화 양상을 연대기적으로 파악하였다. 본 연구를 통해 MISQ에 게재된 IS 연구의 변화 양상을 살펴봄으로써, IS 연구분야의 발전 방향을 예측하고, IS 분야의 연구자들에게 새로운 연구방향을 제시하여 미래 지향적인 연구를 진행하는 데 실질적인 도움을 줄 수 있을 것으로 기대한다.

• Journal of Communications and Networks
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• 제11권2호
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• pp.134-147
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• 2009

Tracking and exploiting instantaneous spectrum opportunities are fundamental challenges in opportunistic spectrum access (OSA) in presence of the bursty traffic of primary users and the limited spectrum sensing capability of secondary users. In order to take advantage of the history of spectrum sensing and access decisions, a sequential decision framework is widely used to design optimal policies. However, many existing schemes, based on a partially observed Markov decision process (POMDP) framework, reveal that optimal policies are non-stationary in nature which renders them difficult to calculate and implement. Therefore, this work pursues stationary OSA policies, which are thereby efficient yet low-complexity, while still incorporating many practical factors, such as spectrum sensing errors and a priori unknown statistical spectrum knowledge. First, with an approximation on channel evolution, OSA is formulated in a multi-armed bandit (MAB) framework. As a result, the optimal policy is specified by the wellknown Gittins index rule, where the channel with the largest Gittins index is always selected. Then, closed-form formulas are derived for the Gittins indices with tunable approximation, and the design of a reinforcement learning algorithm is presented for calculating the Gittins indices, depending on whether the Markovian channel parameters are available a priori or not. Finally, the superiority of the scheme is presented via extensive experiments compared to other existing schemes in terms of the quality of policies and optimality.

• 대한임베디드공학회논문지
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• 제3권4호
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• pp.218-228
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• 2008

The convergence of broadcasting and telecommunication services is being accelerated by broadband networks, digital broadcasting and Web2.0. This paper describes the definition and service characteristics of IPTV as a representative of broadcasting and telecommunication convergence services. Especially, the changes of infrastructure and technology for IPTV2.0 are addressed in terms of the service features of mobility, intelligence and participation. IPTV2.0 shall be characterized by the open IPTV service based on Web2.0 and the mobile IPTV service over the heterogeneous networks employing various wireless/wired access technologies. The IP Multimedia Subsystem (IMS) and Service Delivery Platform (SDP) technologies are increasingly considered to support the personalization and openness. The mobility management technology is being evolved to provide QoS-guaranteed mobile communication services to users at anytime and anywhere. IPTV2.0 services and platforms are also anticipated to be core components to achieve knowledge-based ubiquitous society. IPTV2.0 contents are required to be integrated with the enhanced metadata to efficiently support search, selection, convergence and delivery of the contents. Moreover, those contents shall be enhanced to provide the scalable services which is adaptable to the network status and user preferences. Therefore, the networking technologies for IPTV2.0 should tightly cooperate with application services and adaptive contents. Those technologies will be developed to construct the ubiquitous content service platform considering the evolution of networks and various converged services.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2009년도 추계학술발표대회
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• pp.33.1-33.1
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• 2009

To date, nanostructured tungsten oxides with a variety of stoichiometries, such as WO3, WO2.9, W18O49, and WO2, have been prepared, because they are promising candidates for applications such as gas sensors, photocatalysts, electrochromic devices, and field emission devices. Among them, W18O49 and WO2 have been widely studied due to their outstanding chemical sensing, catalytic, and electron emissive properties. Here we report, for the first time, a one-pot solution-phase route to synthesizing a novel composite hierarchical hollow structure without adding catalysts, surfactants, or templates. The products, consisting of a WO2 hollow core sphere surrounded by a W18O49 nanorod shell (yielding a sea urchin-like structure), were generated as discrete structures via Ostwald ripening. To our knowledge, this type of composite hierarchical core/shell structure has not been reported previously. The morphological evolution and the detailed growth mechanism were carefully studied. We also demonstrate that the size of the hollow urchins is readily tunable by controlling the reactant concentrations.Interestingly, although bulk tungsten oxides are weakly paramagnetic or diamagnetic, the as-prepared products show unusual ferromagnetic behavior atroom temperature. The urchin structures also show a very high Brunauer-Emmet-Teller (BET) surface area, suggesting that they may potentially be applied to chemical sensor or effective catalyst technologies.

• 한국운동역학회지
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• 제12권2호
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• pp.407-415
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• 2002

Athletic products must meet the needs of athletes and the demands imposed by sports through innovative design. These needs of athletes and requirements of sports are performance, protection and comfort related. In depth knowledge of anatomy and physiology, etiology of commonly reported injuries, and lower extremity mechanics form the basis of product creation/engineering. Game analysis which entails time and frequency surveys of the skills performed during a game, interviews with athletes and coaches, and discussions with medical staffs are used to identify the skills that are critical to the needs of athletes. In lab full biomechanical analyses of these skills and/or physiological responses of the athletes lead to clear functional criterions that serve as guidelines to be met by the design team. The concepts created by the design team are in turns subjected to the same battery of biomechanical analyses. The learning gathered through this pluridisciplinary process is used to further evolve design concepts. The evolution-testing loop is repeated until biomechanical and/or physiological, mechanical and perceptual tests indicate that the design concept meets the established functional design criterions. At that time, the design concepts is ready for manufacturing research and development. Additional biomechanical and physical tests are performed through that phase to confirm that the manufacturing processes preserve the functionality of the design concept. Durability and long term performance of production samples are evaluated through a final three month long weartest program. A rigorous research/testing program is crucial to create and engineer sport products that meet the performance, protection.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2004년도 추계 종합학술대회 논문집
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• pp.36-42
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• 2004

근대 산업사회에서 현대 지식기반 사회에 이르러 문화에 대한 관심이 증가하고 있다. 중세의 신 중심 사상에서 인간 중심 사상으로의 중심이동은 이제 생명 복제와 같은 과학 기술 발달과 함께 인류가 신의 영역에 점차 가까워지는 단계에 이르게 되었다. 이러한 급진적인 변화의 흐름에서도 인류 문화의 진화는 더디게만 느껴진다. 생명 경시, 종교 전쟁, 환경 파괴, 적자생존의 자본주의 제도 등은 우리가 바라는 인류공영의 발목을 옥죄는 듯하다. 본 논문은 이러한 현대의 문화 개념과 정체성을 되짚어 보고 21세기라는 새로운 시대의 그릇에 담길만한 문화의 개념을 '물'의 특성을 가진 'SeaCricle'이라는 새로운 용어로 재정의해 보고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4753-4758
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• 2014

In recent times, a number of studies have provided evidence that biotoxins present great potential as antitumor agents, such as snake venom, bee venom, some bacteria toxins and plant toxins, and thus could be used as chemotherapeutic agents against tumors. The biodiversity of venoms and toxins make them a unique source from which novel anticancer agent may be developed. Biotoxins, also known as natural toxins, include toxic substances produced by plants, animals and microorganisms. Here, we systematically list representative biological toxins that have antitumor properties, involving animal toxins, plant toxins, mycotoxins as well as bacterial toxins. In this review, we summarize the current knowledge involving biotoxins and the active compounds that have anti-cancer activity to induce cytotoxic, antitumor, immunomodulatory, and apoptotic effects in different tumor cells in vivo or in vitro. We also show insights into the molecular and functional evolution of biotoxins.

• 대한한의학원전학회지
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• 제33권1호
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• pp.197-205
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• 2020

Objectives : We analyzed the descriptions of Doek(德)·Qi(氣)·Saeng(生)·Jeong(精)·Sin(神)·Hon(魂)·Baek(魄)·Sim(心)·Ui(意)·Ji(志)·Sa(思)·Ji(智)·Ryeo(慮)·Ji(智) which are the concepts mentioned in the beginning of the ≪Lingshu·Benshen≫. Methods : We reinterpreted this verse in ≪Lingshu·Benshen≫ from the viewpoint of evolution and development of mental function and considered it in relation to the knowledge of modern psychology and brain science. Results & Conclusions : The reproductive essence of the parents are combined, primitive essence (元精) is created and simultaneously primitive spirit is born. Primitive spirit first differentiates into Hon and Baek. Hon and Baek are instinctive mental functions. Up to this point, because the process is completed before birth, primitive spirit, Hon, and Baek are innate spirit. Ui, Ji, Sa, Ryeo and Ji are the rational thinking abilities as mental functions that develop actively after birth. This is called conscious spirit and acquired spirit. Analyzing the contents of , it can be said that the mental function is divided into four layers of primitive spirit-Baek-Hon-conscious spirit.