• Title/Summary/Keyword: Knee Osteoarthritis

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Evaluation of the Effectiveness and Safety of Zanthoxylum piperitum Leaf Extract against Mild Degenerative Osteoarthritis of Knee: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (경증의 퇴행성 슬관절염에 대한 초피나무잎 추출물의 유효성 및 안전성 평가: 무작위 배정, 이중맹검, 위약대조 임상연구)

  • Jeong, Ji-Hong;Lee, Soo-Hwan;Yoon, Hong-Ryoul;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.167-191
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    • 2021
  • Objectives Degenerative osteoarthritis of knee is a disease with an increasing number of patients worldwide and its general treatments have some side effects. Methods 102 subjects were classified into test group 1, test group 2, and control group, and clinical trial products were taken for 12 weeks. The effectiveness was evaluated with changes in visual analogue scale, Korean-Western Ontario and McMaster Universities Osteoarthritis Index, inducible nitric oxide synthase, and cyclooxygenase-2. Results Both test group 1 and test group 2 were effective in reducing the pain of degenerative osteoarthritis of knee, and only test group 2 was effective in improving the ability to perform daily activities. No clinically significant changes were observed for any safety parameter. Conclusions In conclusion, the data of this study indicate that Zanthoxylum piperitum leaf extract has effectiveness and safety against mild degenerative osteoarthritis of knee.

The Correlation between Acupuncture Therapy on Knee Osteoarthritis and BMI (퇴행성 슬관절염의 침치료 호전도와 BMI와의 상관성)

  • Yeo, In Ho;Kim, Jung Hyun;Jung, Se Ho;Jo, Na Young;Roh, Jeong Du;Kim, Kap Sung;Lee, Seung Deok;Kim, Eun Jung;Lee, Cham Kyul;Lee, Eun Yong
    • Journal of Acupuncture Research
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    • v.30 no.3
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    • pp.101-107
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    • 2013
  • Objectives : The purpose of this study is to investigate the correlation between acupuncture therapy on knee osteoarthritis and BMI. Methods : Data on assessment measurements of knee osteoarthritis and obesity were obtained from 31 patients suffering from knee osteoarthritis from May, 2011 to September, 2012. The assesment measurements consisted of body mass index(BMI), visual analogue scale(VAS) and Western Ontario and McMaster Universities(WOMAC) index. Statistical correlations among assessment measurements were evaluated by examining the Pearson's correlation coefficients. Results : 1. The average age of all patients was $58.87{\pm}9.48$(male : $63.67{\pm}11.34$, female : $57.72{\pm}8.86$). 2. The average BMI of all patients was $25.41{\pm}3.06kg/m^2$. According to clinical definition of obesity by Korean Society for the Study of Obesity, 25.81% of all patients was within normal weight, 25.81% was overweight, 38.71% was obesity and 9.67% was morbid obesity. 3. There were no significant correlations in statistics among assessment measurements. Conclusions : There is significant correlation between knee osteoarthritis and obesity according to many clinical and experimental researches. So more studies on correlation between knee osteoarthritis and obesity and development of assessment measurement are needed.

The Study on the Questionnaire Analysis and Agreement Diagnosis of the Same Patients Using Differentiation of Symptoms and Signs on Chronic Knee Joint Pain Including Osteoarthritis of Knee Joint (퇴행성 슬관절염 환자를 포함한 만성 슬통환자의 설문분석과 경락허실변증 진단일치도에 관한 연구)

  • Lee, Jong-Deok;Lee, Sang-Kwan;Lee, Sung-Young;Moon, Hyung-Cheol;Choi, Sun-Mi;Chung, Young-Hae;Kim, Sung-Chul
    • Journal of Acupuncture Research
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    • v.23 no.1
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    • pp.71-93
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    • 2006
  • Objectives : This study is performed for proposing reasonable clinical study protocol at International standard clinical study of osteoarthritis of Knee Joint. Methods : We gave the eighteen oriental medicine doctors the questionnaire and the video about female patient who diagnosed Knee joint of osteoarthritis above 60 years old and they tested same patients using differentiation of symptoms and signs. Then they retested it after We educated them with diagnosis education text. Conclusion : The improvement of diagnosis agreement can be possible by developing standardized the same patients using differentiation of symptoms and by reeducation about it.

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Development and Evaluation of a Joint Health Self-management Program for the Elderly with Knee Osteoarthritis in Communities: Applying the IMB Model (재가 무릎 골관절염 환자의 관절건강 자가관리 프로그램 개발 및 효과: IMB 모델 적용)

  • Kim, Young-il;Park, Jeong Sook
    • Research in Community and Public Health Nursing
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    • v.28 no.1
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    • pp.55-68
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    • 2017
  • Purpose: The purpose of this study is to develop and evaluate a joint health self-management program for knee osteoarthritis elders in communities. Methods: This program was developed based on the IMB (information-motivationbehavioral skills) model. The program methods include education, setting and achieving goals, sharing experiences, telephone counseling, and self-monitoring. The topics of the program include joint assessment, exercise, massage, joint protection, medication, depression management, diet, and healthcare approach. The research was conducted following the principles of the nonequivalent control group pretest-posttest design. Participants were 26 subjects in the experimental group, and 27 subjects in the control group. The experimental group participated in the self-management program, and the control group received general education. Results: Both post-test scores of personal motivation, social motivation, behavior skill, self-management behavior, joint pain, joint stiffness, physical function disability, right knee extension, left knee extension, and depression were significantly different between the experimental group and the control group. Conclusion: The results of the study can be used to develop and standardize a systematic joint health self-management program. Further research is highly recommended to develop a strategy to continuously facilitate self-management of osteoarthritis patients' procedures.

Study on Effect of KWOMAC of a Contact Lateral-Wedged Insole with Strapping in Patients with Varus Deformity Osteoarthritis of the Knee (내반슬 골관절염 환자에 대한 밀착형 외측 쐐기 스트랩 발받침이 한국형 WOMAC에 미치는 영향에 관한 연구)

  • Lee, Sang-Yang;Gong, Won-Tae
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.13 no.1
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    • pp.26-35
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    • 2007
  • The purpose are to demonstrate the pain, stiffness, and physical function by the Korean Western Ontario MacMaster University(KWOMAC) score of the patients with varus deformity osteoarthritis of the knee after treatment period. Twenty outpatients with knee osteoarthritis(OA) were randomized and divided into the control(n=10) and wedge(n=10) groups. The remission scores of the KWOMAC index of severity for knee OA were compared between the groups. The result of repeated two-way ANOVA's revealed that a contact lateral-wedged insole with strapping produced significantly differences in the pain and physical function score between groups after treatment period(P<0.05), but it was not significant differences in the stiffness score between groups(P>0.05). These results suggest that the pain relief and improvement in function reported by patients with osteoarthritis while using lateral-wedged insole with strapping may be achieved by a reduction in external varus moment and medial compartment load.

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Adverse Events of Electronic Moxibustion Treatment for Knee Osteoarthritis: Case Reports and a Literature Review

  • Oh, Yoona;Lee, Jisun;Kim, Yeonhak;Kim, Eun Seok;Kim, Kun Hyung;Lee, Byung Ryul;Yang, Gi Young
    • Journal of Acupuncture Research
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    • v.39 no.1
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    • pp.29-35
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    • 2022
  • Background: Electronic moxibustion has the advantage of temperature control and maintenance, and overcomes the limitations of the existing moxibustion process without the use of the combustion process. However, as the application of electronic moxibustion in clinical practice has increased, safety issues are emerging. Methods: Clinical cases of electronic moxibustion treatment for knee osteoarthritis where burns occurred were collected. In addition, adverse events reported in clinical studies using electronic moxibustion for patients with knee osteoarthritis were collected from studies retrieved from Korean and international databases. Results: There were 3 cases of superficial 2nd degree burns retrospectively collected through chart reviews. Among the selected 5 studies for literature review, 2 studies reported adverse events which were burns milder than those reported in these 3 cases in this retrospective case review. Conclusion: Since the risk of superficial 2nd degree burn was discovered in the cases reviewed, further research on safe electronic moxibustion treatment is required without compromising the effectiveness of moxibustion.

Cooled radiofrequency ablation of genicular nerves for knee osteoarthritis

  • Myong-Hwan Karm;Hyun-Jung Kwon;Chan-Sik Kim;Doo-Hwan Kim;Jin-Woo Shin;Seong-Soo Choi
    • The Korean Journal of Pain
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    • v.37 no.1
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    • pp.13-25
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    • 2024
  • Knee osteoarthritis (OA) is a prevalent and debilitating musculoskeletal condition that significantly affects the quality of life of millions of individuals worldwide. In recent years, cooled radiofrequency ablation (CRFA) has become a viable treatment option for knee OA. This review thoroughly evaluated the existing literature on CRFA therapy for knee OA. It delved into the mechanisms behind CRFA, evaluated its clinical efficacy, and investigated potential avenues for future research and application. The insights gained from this review are crucial for healthcare professionals, researchers, and policymakers, offering an updated perspective on CRFA's role as a viable therapeutic option for knee OA.

The Effect of Sa-am acupuncture on Knee Osteoarthritis

  • Min, Moo-Hong;Choi, Yeong-Gon;Kim, Yun-Ju;Park, Hi-Joon;Lee, Sam-Chool;Joo, Ho-No;Han, Seung-Moo;Lim, Sa-Bi-Na
    • Korean Journal of Acupuncture
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    • v.26 no.4
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    • pp.53-66
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    • 2009
  • Objective : Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method : This study was conducted as a prospective, randomized, controlled, and patient- and investigator-blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results : Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t-test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions : Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.

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Alcohol neurolysis of genicular nerve for chronic knee pain

  • Dass, Rushin Maria;Kim, Eunsoo;Kim, Hae-kyu;Lee, Ji Youn;Lee, Hyun Ju;Rhee, Seung Joon
    • The Korean Journal of Pain
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    • v.32 no.3
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    • pp.223-227
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    • 2019
  • Radiofrequency neurolysis (RFN) of the genicular nerves has recently become accepted as an effective technique to alleviate knee pain particularly in patients with knee osteoarthritis (OA) or postoperative pain. However, genicular nerve RFN can produce high procedure and equipment costs, longer procedural times, procedure-related pain, and failure rate of over 25%. We are presenting two cases of alcohol neurolysis of the genicular nerve using fluoroscopy and ultrasonography in patients with knee OA or persistent postsurgical pain of the knee. Alcohol neurolysis of the genicular nerve with dual imaging modality can be a cheap, safe and effective method in patients with chronic knee pain.

Effects of Jetongdan on the Quality of Life in Patients with Osteoarthritis of Knee (제통단이 퇴행성 슬관절염 환자의 삶의 질에 미치는 영향)

  • Seo, Byung-Kwan;Ryu, Seong-Ryong;Kang, Jung-Won;Woo, Hyun-Su;Lee, Jae-Dong;Choi, Do-Young;Kim, Keon-Sik;Lee, Doo-Ik;Lee, Yun-Ho;Lee, Sang-Hoon
    • Journal of Acupuncture Research
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    • v.22 no.6
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    • pp.219-228
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    • 2005
  • Objectives : to evaluate the effects of Jetongdan, the newly developed herbal medicine, on the quality of life in patients with osteoarthritis of knee Methods : Placebo-controlled, randomized clinical trial on the 80 patients with osteoarthritis of the knee was fulfilled. After enrollment, they took medication as they enrolled. And they were asked to answer the questionnaires (Korean Health Assessment Questionnaire (KHAQ), Lequesne's functional index (LFI), visual analogue scale (VAS)) and analysed with the erythrocyte sedimentation rate (ESR) at baseline, after 4 weeks and 8 weeks of medication. Results : Total KHAQ score, some categories of KHAQ like hygiene, activities were significantly improved after 8 weeks of medication. And the change of the KHAQ score was significantly correlated with the change of VAS. But LFI, VAS, ESR level was not significantly improved, and it was considered because of the short medication period and small size of study population. Conclusion : In conclusion, Jetongdan could improve the health-related quality of life in patients with osteoarthritis of knee. Further study in the large population, in long period were recommended.

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