Effects of Jetongdan on the Quality of Life in Patients with Osteoarthritis of Knee

제통단이 퇴행성 슬관절염 환자의 삶의 질에 미치는 영향

  • Seo, Byung-Kwan (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Ryu, Seong-Ryong (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Kang, Jung-Won (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Woo, Hyun-Su (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Jae-Dong (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Choi, Do-Young (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Keon-Sik (Department of Anethesiology, College of Medicine, Kyung Hee University) ;
  • Lee, Doo-Ik (Department of Anethesiology, College of Medicine, Kyung Hee University) ;
  • Lee, Yun-Ho (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Sang-Hoon (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University)
  • 서병관 (경희대학교 한의과대학 침구학교실) ;
  • 류성룡 (경희대학교 한의과대학 침구학교실) ;
  • 강중원 (경희대학교 한의과대학 침구학교실) ;
  • 우현수 (경희대학교 한의과대학 침구학교실) ;
  • 이재동 (경희대학교 한의과대학 침구학교실) ;
  • 최도영 (경희대학교 한의과대학 침구학교실) ;
  • 김건식 (경희대학교 의과대학 마취통증의학과) ;
  • 이두익 (경희대학교 의과대학 마취통증의학과) ;
  • 이윤호 (경희대학교 한의과대학 침구학교실) ;
  • 이상훈 (경희대학교 한의과대학 침구학교실)
  • Published : 2005.12.20

Abstract

Objectives : to evaluate the effects of Jetongdan, the newly developed herbal medicine, on the quality of life in patients with osteoarthritis of knee Methods : Placebo-controlled, randomized clinical trial on the 80 patients with osteoarthritis of the knee was fulfilled. After enrollment, they took medication as they enrolled. And they were asked to answer the questionnaires (Korean Health Assessment Questionnaire (KHAQ), Lequesne's functional index (LFI), visual analogue scale (VAS)) and analysed with the erythrocyte sedimentation rate (ESR) at baseline, after 4 weeks and 8 weeks of medication. Results : Total KHAQ score, some categories of KHAQ like hygiene, activities were significantly improved after 8 weeks of medication. And the change of the KHAQ score was significantly correlated with the change of VAS. But LFI, VAS, ESR level was not significantly improved, and it was considered because of the short medication period and small size of study population. Conclusion : In conclusion, Jetongdan could improve the health-related quality of life in patients with osteoarthritis of knee. Further study in the large population, in long period were recommended.

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