• 제목/요약/키워드: Kim Jung-Il

검색결과 6,106건 처리시간 0.037초

Effect of Cordycepin on the Expression of the Inflammatory Cytokines TNF-alpha, IL-6, and IL-17A in C57BL/6 Mice

  • Seo, Min Jeong;Kim, Min Jeong;Lee, Hye Hyeon;Park, Jeong Uck;Kang, Byoung Won;Kim, Gi-Young;Rhu, En Ju;Kim, Jung-In;Kim, Kwang Hyuk;Jeong, Yong Kee
    • Journal of Microbiology and Biotechnology
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    • 제23권2호
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    • pp.156-160
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    • 2013
  • Culture supernatants of splenocytes from C57BL/6 mice were exposed to 0.3, 1.0, and 3.0 ${\mu}g/ml$ cordycepin plus 3.0 ${\mu}g/ml$ lipopolysaccharide (LPS) to investigate the effects of cordycepin (3'-deoxyadenosine) on the production of inflammatory cytokines. Coadministration of 3.0 ${\mu}g/ml$ cordycepin with LPS in cultured murine spleen cells significantly diminished expression of the inflammatory cytokines tumor necrosis factor-${\alpha}$ and interleukin-6 (IL-6) in a time-dependent manner. Expression of the inflammatory cytokine IL-17A was substantially downregulated in a timeand concentration-dependent manner at all cordycepin concentrations. These findings suggest that cordycepin downregulates the immediate hypersensitivity reaction stimulated by LPS.

Dental Management of Sjogren s Syndrome

  • Kim Jun-Hyung;Jung Il-Young
    • 대한치과보존학회:학술대회논문집
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    • 대한치과보존학회 2006년도 Spring Scientific Meeting(the 125th) of Korean Academy of Conservative Dentistry
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    • pp.245-245
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    • 2006
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