• 한국전자현미경학회:학술대회논문집
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• 한국현미경학회 2005년도 제36차 춘계학술대회 및 제3회 HVEM 이용자 워크샵
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• pp.138-140
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• 2005

• Bulletin of the Korean Chemical Society
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• 제13권4호
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• pp.346-348
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• 1992

• Pediatric Infection and Vaccine
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• 제3권2호
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• pp.133-138
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• 1996

Purpose : In the treatment of MRSA infection, rapid detection of MRSA is extremely important. The mecA gene codes the new drug resistant polypeptides called PBP2' which mediates the clinically relevant resistance to all beta-lactam antibiotics. The identical mecA gene has been found in coagulase-negative staphylococcus with the methicillin-resistant phenotype. On the other hand, the femA gene was absent from coagulase negative staphylococcus strains with the methicillin resistant phenotype. This study is aimed at early detection and definite diagnosis of MRSA. Methods : A total of 24 MRSA strains were studied. All strains were tested for antimicrobial susceptibility and purified DNA. We amplified both mecA and femA genes by PCR in 24 strains. Results : In MRSA all the 16 strains (100%) carried femA gene and 11 strains (68.7%) carried mecA gene. In contrast, in methicillin sensitive staphylococcus all the 8 strains (100%) carried femA and only 3 strains (37.5%) were detected mecA. Conclusions : As results, there are difference in the phenotype and genotype of methicillin resistance by PCR of mecA and femA. Such disparities between methicillin resistance and the presence of mecA gene suggest the presence of control gene of the mecA.

• 동의생리병리학회지
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• 제17권4호
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• pp.898-904
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• 2003

Pellinus linteus has been used for the prevention of cancer traditionally. There are three origins of Pellinus linteus, Korea, China and Cambodia. However, their immunological activities were not evlauated comparatively. Thus, this study was done to evaluate immunomodulatory effects of Phellinus linteus(PL) from Korea, china and cambodia, We confirmed PL showed two major protein bands, 50 kDa and 80 kDa by protein analysis. These PL effectively upregulated the expressions of IL-2 at 10 ug/ml and GM-CSF, IL-4, IL-10, IL-12(p35), IL-12(p40), IL-18, IFN-r in all concentrations. However, Korea-PL upregulated the expression of IL-12 more effectively than the other PLs. It intended to increase NO with no significance. Those results indicate Phellinus linteus had cytokine modulating effect

• Journal of Acupuncture Research
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• 제19권3호
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• pp.51-63
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• 2002

Objective : The purpose of this study is to investigated that effect of Bupleuri Radix Herbal-acupuncture solution (BRHS) on the celluar immune response in mice with adjuvant induced arthritis, performed several experimental items : those are paw edema, IL-1b, IL-6, IL-8, PNF-a and $PGE_2$. Methods : All the male Sprague Daeley mice used in this study were bred and maintained in our pathogen-free mouse colony and were 8 weeks of age at the start of the experiment. The experimental model of arthritis was induced by injection of $50{\mu}g/{\mu}{\ell}$ adjuvant(mineral oil mixed Mycobacterium butyricum). Bupleuri Radix Herbal-acupuncture solution (BRHS) was injected into $ST_{36}$(足三理) of mice daily for 21 days. Immunohistological analysis was carried out to assess paw edema, IL-$1{\beta}$, IL-6, IL-8, PNF-${\alpha}$ and $PGE_2$expression in synovial membrance and sera Bupleuri Radix Herbal-acupuncture solution(BRHS) injected. Results : At day 21 post arthritis onset, immunohistological studies using monoclonal antibodies showed that Bupleuri Radix Herbal-acupuncture solution (BRHS) group had decreased expression of IL-$1{\beta}$, IL-6, IL-8, PNF-${\alpha}$ and $PGE_2$ at inflamatory cytokines production and edema compared with control group. Conclusion : Bupleuri Radix Herbal-acupuncture solution (BRHS) inhibited infammatory cytokines production and edema in adjuvant induced arthritic mice. Thus, Herbal-acupuncture solution may have prevention.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1998년도 한국생물과학협회 학술발표대회
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• pp.342.2-342
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• 1998

No Abstract, See Full Text

• 대한화학회지
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• 제43권4호
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• pp.8-489
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• 1999

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2019년도 춘계학술논문요약집
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• pp.297-298
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• 2019

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1992년도 제31차 춘계학술대회
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• pp.195-195
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• 1992

• Journal of Acupuncture Research
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• 제19권2호
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• pp.177-188
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• 2002

Objective : The purpose of this study is to investigate the immunohistological effect of Buthus martensi Karsch Herbal-acupuncture in treating the arthritis, performed several experimental items : those are paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$. Methods : All the male Sprague Dawley rats used in this study were bred and maintaned in our pathogen-free rat colony and were 8 weeks of age at the start of to experiment. The experimental model of arthritis was induced by injection of $50{\mu}g/{\mu}{\ell}$ adjuvant(mineral oil mixed Mycobacterium butyricum). Buthus martensi Karsch Herbal-acupuncture was injected into ST36(足三里) of rats daily for 21 days. Immunohistological analysis was carried out to assess paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$ expression in synovial membrane and sera Buthus martensi Karsch Herbal-acupuncture injected. Results : Buthus martensi Karsch Herbal-acupuncture group showed a decrease with statistical significance, in paw edema, $IL-1{\beta}$, IL-6, IL-8, $TNF-{\alpha}$ and $PGE_2$ in synovial membrane and sera compared with control group. Conclusion : Buthus martensi Karsch Herbal-acupuncture stimulation inhibited the development of immunity to adjuvant induced arthritis in rats. Thus, Buthus martensi Karsch Herbal-acupuncture may have preventive effects on autoimmune inflammatory joint diseases as arthritis. The effect of Buthus martensi Karsch Herbal-acupuncture on the immune function and the disease activity in patients with arthritis warrants further investigation.