• Proceedings of the Korean Nuclear Society Conference
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• 2005.10a
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• pp.807-808
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• 2005

• 한국도로학회:학술대회논문집
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• 2005.11a
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• pp.169-176
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• 2005

• IMMUNE NETWORK
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• v.7 no.4
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• pp.186-196
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• 2007

Background: Although IL-12 has been widely accepted to playa central role in the control of pathogen infection, the use of recombinant IL-12 (rIL-12) as a vaccine adjuvant has been known to be ineffective because of its rapid clearance in the body. Methods: To investigate the effect of sustained release of IL-12 in vivo in the peptide and protein vaccination models, rIL-12 was encapsulated into poly ($A_{DL}$-lactic-co-glycolic acid) (PLGA). Results: We found that codelivery of IL-12-encapsulated microspheres (IL-12EM) could dramatically increase not only antibody responses, but also antigen-specific $CD4^+\;and\;CD8^+$ T cell responses. Enhanced immune responses were shown to be correlated with protective immunity against influenza and respiratory syncytial virus (RSV) virus challenge. Interestingly, the enhancement of $CD8^+$ T cell response was not detectable when $CD4^+$ T cell knockout mice were subjected to vaccination, indicating that the enhancement of the $CD8^+$ T cell response by IL-12EM is dependent on $CD4^+$ T cell "help". Conclusion: Thus, IL-12EM could be applied as an adjuvant of protein and peptide vaccines to enhance protective immunity against virus infection.

• Tribology and Lubricants
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• v.24 no.5
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• pp.269-274
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• 2008

Carbon nanotube composite is considered to be a good candidate material for composite material because of its excellent mechanical property and low density under high temperature as well as good wear and frictional properties. In this study, tribological characteristics of carbon nanotube aluminum composite were evaluated using pin-on-disk wear tester. Spark Plasma Sintering method is more effective than Hot Pressing method in terms of wear and friction. The composite with 1% CNT has the lowest friction and wear characteristic.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2011.11a
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• pp.155-158
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• 2011

유속을 측정하기 위한 다양한 기법들 가운데 양방향 저속 차압 프로브(bi-directional low velocity pressure probe)는 고온의 연소생성물이 존재하는 조건에서 화재유동장의 속도 측정에 가장 적합한 방법으로 인식되어 왔다. 그러나 양방향 유속계의 프로브 상수(probe constant)는 레이놀즈 수와 유동과 프로브의 받음각(attack angle)에 크게 영향을 받게 된다. 본 연구에서는 화재유동장 측정 기법들을 비교 평가하고 양방향 유속계의 받음각에 따른 프로브 상수의 변화를 실험적으로 평가하여 양방향 유속계의 측정 오차를 정량함으로서 화재 유동장 측정의 신뢰성 향상을 위한 기초자료를 제공하고자 한다.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.334.3-334.3
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• 2002

Ginseng(the root of Panax ginseng C.A. Meyer, Araliaceae) has been used for thousands of years as a traditional medicine in Asian countries. The main components of Ginseng are ginsenoside Rb1, Rb2 and Rc. These compounds are transformed by intestinal microflora. The main metabolite of ginsenosides was compoud K (IH-901). The transformed compound K shows an antimetastic or anticarcinogenic effect by blocking tumor invasion or preventing chromosomal aberration and tumorigenesis. Therefore. we isolated and characterzed ginseng saponin-metabolizing bacteria from human intestinal microffora. Among 200 tested intestinal bacteria. we found 78 bacteris to transform glnseng senseng saponins to compound K. These bacteria were seperated into three group: the first group highy produced ginsenside Rd (29) the second grop produced potently ginsenoside F2 (21) and the third produced compound K(28)

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.176.3-177
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• 2002

• Proceedings of the Korea Multimedia Society Conference
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• 2012.05a
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• pp.298-299
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• 2012

• 한국도로학회:학술대회논문집
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• 2009.11a
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• pp.553-556
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• 2009

• The Bulletin of The Korean Astronomical Society
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• v.29 no.2
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• pp.51.2-51.2
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• 2004