• Research in Community and Public Health Nursing
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• v.14 no.2
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• pp.263-273
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• 2003

Objectives: The purpose of this study was to identify the family phenomenon and characteristics by ICNP such as family shape, life standard. area, and development stage. Method: 1. Sample size was 115. 2. Data analysis method included frequency analysis including ratio. Results: 1. On the distribution of the family phenomena by family shape, the nuclear family showed a higher ratio on the distribution in family communication and the unhealthy life style. The nuclear family was related to children andhad a higher ratio on the inadequate care management of the sick member. The extended family showed the highest ratio on the inadequate care management of sick member. 2. On the distribution of the family phenomena by family life standard, the family with medium life standard showed a higher ratio on the inappropriate family coping, whereas the family with lower life standard appeared to have a higher ratio on the inadequate care management of the sick member. 3. On the distribution of the family phenomena by area. the large city area showed the highest ratio on the inappropriate family coping, the medium and small city area appeared to have the highest ratio on the unhealthy life style. The county area showed the highest ratio on the inadequate care management of sick member. 4. On the distribution of the family phenomena by development stage, the family in rearing period showed a higher ratio on the inappropriate family coping and the lack of family intimacy. Families with preschool children showed a higher ratio on the unhealthy life style, and families with school age children showed the highest ratio on the inappropriate family coping. Families with adolescents appeared to have the highest ratio on the disturbance in family communication, and families with launching young adults showed the highest ratio on the inadequate care management of sick member. 5. On the distribution of the family characteristics by family shape, the nuclear family showed a higher ratio on the family characteristics such as less communication chances among family members and neglect of general child rearing, whereas the third generation family appeared to have a higher ratio on the characteristics such as overburden of housewife's role and short of caring among family members. 6. On the distribution of the family characteristics by family life standard, the family of medium life standard showed higher ratio on the family characteristics such as a few communication chance among family and overburden of housewife's role, and the family of lower life standard appeared to higher ratio on the family characteristics such as short of caring among family members. 7. On the distribution of the family characteristics by area. the large city area showed a higher ratio on the family characteristics such as overburden of housewife's role and neglect of general child rearing. The medium and small city area appeared to have a higher ratio on the family characteristics such as less communication chancec among family members. The county area showed a higher ratio on the family characteristics such as short-term care among family members. 8. On the distribution of the family characteristics by development stage, the family with rearing period showed a higher ratio on the family characteristics such as neglect of general child rearing. Families with preschool children showed a higher ratio on the family characteristics such as less communication chancec among family members. Families with school age children showed a higher ratio on the family characteristics such as overburden of housewife's role. Families with adolescents appeared to have a higher ratio on the family characteristics such as less communication chances among family members. Families with launching young adults showed a higher ratio on the family characteristics such as less communication chances and short-term care among family members.

• Journal of Applied Biological Chemistry
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• v.53 no.1
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• pp.13-20
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• 2010

Biological activities such as anti-oxidative and anti-microbial of the Seungmakalgeuntang, a traditional prescription, were evaluated. The electron donating ability of water, ethanol, supercritical fluid and 1,3-butylene glycol extract of Seungmakalgeuntang showed more than 50% at a 100 ppm concentration. At a 1000 ppm concentration, the superoxide dismutase-like activities of ethanol and supercritical fluid extract of Seungmakalgeuntang showed less than 50%. xanthine oxidase inhibition effect of the supercritical fluid extract showed more than 70% at a 1,000 ppm concentration, which was higher than vitamin C. From the measurement on lipid oxidation, the $Fe^{2+}$ chelating abilities of the supercritical fluid extract of Seungmakalgeuntang was more than 60% at a 100 ppm concentration. Also the $Cu^{2+}$ chelating abilities of supercritical fluid extract Seungmkalgeuntang was showed more than 60% at a 500 ppm concentration. Clear zones formed by sample against the human skin-resident microflora such as Staphylococcus epidermidis, Staphylococcus aureus and Propionibacterium acne of ethanol and supercritical fluid extract of Seungmakalgeuntang showed the highest among all the extracts tested using a 4mg/disc. The minimum inhibitory concentration (MIC) against both S. epidermidis and S. aureus showed 2,500 ppm in the extract of the supercritical fluid.

• Radiation Oncology Journal
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• v.29 no.2
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• pp.63-70
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• 2011

Purpose: To evaluate the extent of pain response and objective response to palliative radiotherapy (RT) for bone metastases from hepatocellular carcinoma according to RT dose. Materials and Methods: From January 2007 to June 2010, palliative RT was conducted for 103 patients (223 sites) with bone metastases from hepatocellular carcinoma. Treatment sites were divided into the high RT dose and low RT dose groups by biologically effective dose (BED) of 39 $Gy_{10}$. Pain responses were evaluated using the numeric rating scale. Pain scores before and after RT were compared and categorized into 'Decreased', 'No change' and 'Increased'. Radiological objective responses were categorized into complete response, partial response, stable disease and progression using modified RECIST (Response Evaluation Criteria In Solid Tumors) criteria; the factors predicting patients' survival were analyzed. Results: The median follow-up period was 6 months (range, 0 to 46 months), and the radiologic responses existed in 67 RT sites (66.3%) and 44 sites (89.8%) in the high and low RT dose group, respectively. A dose-response relationship was found in relation to RT dose (p=0.02). Pain responses were 75% and 65% in the high and low RT dose groups, respectively. However, no statistical difference in pain response was found between the two groups (p=0.24). There were no differences in the toxicity profiles between the high and low RT dose groups. Median survival from the time of bone metastases diagnosis was 11 months (range, 0 to 46 months). The Child-Pugh classification at the time of palliative RT was the only significant predictive factor for patient survival after RT. Median survival time was 14 months under Child-Pugh A and 2 months under Child-Pugh B and C. Conclusion: The rate of radiologic objective response was higher in the high RT dose group. Palliative AT with a high dose would provide an improvement in patient quality of life through enhanced tumor response, especially in patients with proper liver function.

• Journal of Nutrition and Health
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• v.45 no.4
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• pp.336-346
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• 2012

This study was carried out to obtain information related to life styles, nutrition knowledge, and dietary habits according to gender and weight status of college students in Ulsan. The subjects were 324 college students (144 males, 180 females), and they were divided into three groups based on BMI. The average BMI was $21.0kg/m^2$, and the BMI of underweight, normal, and overweight students were 15.4%, 63.0%, and 21.6%, respectively. Among the male students, 0.1% and 34.0%, and among the female subjects, 27.2% and 11.7%, were included in the underweight and overweight groups, respectively. For dietary habits, the rate of skipping breakfast (34.9%) was considerably higher than those skipping lunch and dinner. Overall, the nutrition knowledge score, which was assessed by 15 questions, was somewhat low (44.9/100), yet, it was higher in females than in male students. There were significant differences among gender and weight status in several items of dietary habits such as the speed of eating meals, consuming breakfast on a regular basis, and sleeping hours. 40% of the subjects had appropriate knowledge about high calorie foods with low nutritional value. In the blood analysis of the subjects, males had higher hemoglobin levels than females. Further, more females were included in the risk group of Hb, total cholesterol, and LDL. These results suggest that in order to develop nutrition education programs for college students, differences between gender and weight status, dietary habits, and nutrition knowledge level should be considered.

• Clinical and Experimental Pediatrics
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• v.51 no.7
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• pp.754-759
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• 2008

Purpose : Abnormal activation patterns of Th1/Th2-cells have been suggested to increase the prevalence of allergic diseases. Prevention is regarded as an important corner stone in the management of allergic diseases. In this study, we have investigated the relationship between cord blood levels of IL-4, IL-10, and IL-12 in preterm newborns and the development of allergic respiratory diseases in infancy Methods : Forty-six preterm newborns born at the Ewha Womans University Mokdong Hospital between January 2003 and July 2005, were enrolled for this study, and consent was obtained to test their cord blood samples. Clinical history was obtained from the hospital records. Cord blood was obtained at birth and kept frozen until it was tested. The levels of IL-4, IL-10, and IL-12 were determined by enzyme-linked immunosorbent assay (ELISA). Results : All infants were followed-up for a median of $16.0months{\pm}13.2d$ (range, 12.0 to 36.0 months). Eighteen infants who developed wheezing showed lower cord blood levels of IL-12 ($366.60{\pm}140.40$ vs $435.09{\pm}91.20pg/mL$, P=0.009). Cord blood levels of IL-4 and IL-10 showed no significant difference between the two groups. Four newborns who later developed asthma, and infants with asthma showed lower IL-12 level in the cord blood than other groups. Conclusion : Lower concentration of cord blood levels of IL-12 in newborns who later developed wheezing and asthma suggested that they had abnormal activation patterns of Th1/Th2-cells at the time of birth, and cord blood IL-12 level can be used as a predictor of allergic respiratory diseases.

• Journal of Bio-Environment Control
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• v.27 no.1
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• pp.71-79
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• 2018

This study was conducted to compare the physicochemical properties of newly developed artificial medium and conventional plug medium and to investigate the proper irrigation interval to produce the high quality tomato seedlings. The five existing artificial media (organic medium coir, mixed medium Tosilee and Q plug, and inorganic medium LC and rockwool) and four newly developed artificial medium (mixed medium TP-S1 and inorganic medium PU 14-S1, PU-7B, and PU 15-S1) were used to grow tomato 'Yegwang' with irrigation interval of one-day (14 times), two-day (7 times), and three-day (5 times) for 14 days. The pH was the significantly highest in the PU 15-S1. All growing medium measured were in the range of pH 5.17-6.90. EC was the highest in the Q plug. The initial germination rate was the highest in the PU 15-S1. The final germination rate and mean daily germination were not significantly different in all growing medium except for the PU 14-S1. Growth of tomato seedlings at 15 days after sowing was the greatest in the Q plug. At 29 days after sowing, seedlings were also the greatest in the Q plug, followed by rockwool and PU-7B. Also, growth was better in the one-day interval treatment. As a result, we confirmed the applicability of the artificial medium to tomato plug seedlings in this experiment, and seedlings were the greatest in the Q plug. Therefor, it is considered that adding nutrients to the artificial medium of the newly developed medium PU-7B, and applying the irrigation one-day interval can produces high quality tomato seedlings similar to using Q plug.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.1
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• pp.42-55
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• 2008

Purpose: A new health policy, referred to as the National Health Screening Program for Infants and Children, was launched in November 2007 by the Ministry of Health and Welfare and National Health Insurance Corporation in Korea. We have developed a nutrition-counseling program that was incorporated into this project. Methods: We reviewed the nutritional guidelines published by The Korean Pediatric Society and internationally well-known screening programs such as Bright Future in the United States. We also reviewed the recent Korean national surveys on nutritional issues, including the Korea National Health and Nutrition Examination Survey (KNHANES) and the 2005 National Survey of Physical Body and Blood Pressure in Children and Adolescents. The development of questions, pamphlets, computer programs, and manuals for doctors was carried out after several meetings of researchers and governmental officers. Results: We summarized the key nutritional issues according to age, including breastfeeding in infants, healthier complementary feeding, and prevention of iron deficiency anemia, establishment of healthier diets, as well as dietary prevention of overweight children with an emphasis on physical exercise. We have constructed a new Korean nutrition questionnaire and an anticipatory guidance program based on the primary care schedule of visits at 4, 9, 18, 30, and 60 months of age. Five to eight questions were asked at each visit and age-matched pamphlets for parents and guidelines for doctors were provided. Conclusion: We developed a nutrition-counseling program based on recent scientific evidence for Korean infants and children. Further research on this national program for screening the nutritional problems in detail and setting the therapeutic approaches may help identify areas of success as well as those that need further attention.

• Horticultural Science & Technology
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• v.28 no.4
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• pp.648-655
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• 2010

This study is the first comprehensive report on the molecular cloning, structural characterization, sequence comparison between wild and mutant types, copy number in the genome, expression features and activities of a gene encoding 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) in Korean lawn grass ($Zoysia$ $japonica$). The full length cDNA of the EPSPS from Korean lawn grass ($zj$EPSPS) obtained from a 3' and 5' RACE method was 1540 bp, containing a 1176 bp ORF, a 144 bp leader sequence (5' UTR) and a 220 bp 3' UTR, which was eventually decoded 391 amino acid residues with a molecular mass of 41.74 kDa. The Southern blot detection of the $zj$EPSPS showed that the gene exists as a single copy in the Korean lawn grass genome. Sequence comparison of the $zj$EPSPS gene demonstrated that the glyphosate-tolerant mutant (GT) having a Pro-53 to Ser substitution in the gene seems to have a preferred binding activity of the enzyme to phosphoenol pyruvate(PEP) over glyphosate, which allows the continuous synthesis of aromatic amino acids in the shikimate pathway. From the Northern blotting analysis, the $zj$EPSPS was found to be highly expressed, with continuous increase until 36 hours after 0.5% glyphosate treatment in both wild and mutant samples, but 1.5-fold higher EPSP synthase activity was observed in the tolerant mutant when exposed to the glyphosate treatment. The molecular information of the $zj$EPSPS gene obtained from this study needs to be further dissected to be more effectively applied to the development of gene-specific DNA markers and zoysiagrass cultivars; nevertheless, the glyphosate-tolerant mutant having the featured $zj$EPSPS gene can be provided to turfgrass managers for weed problems with timely adoptable management options.

• Archives of design research
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• v.18 no.2 s.60
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• pp.155-164
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• 2005

Home-service robots need to have sufficient spatial information about the surroundings for interacting with human intelligently and performing services efficiently. It is very important to investigate the efficient interaction style that supports map building task through human-robot collaboration. We first analyzed map building task with a cleaning robot and drew 4 design factors and tentative solutions, including map building procedure (task-preferred procedure/space- preferred procedure), LCD display installation (robot/robot+remote control), navigation method (push type/pull type), feedback modality(GUI/GUI+TTS). The design factors and tentative solutions were defined as independent variables and levels. This research investigated how those variables affect to the human task performance and behavior in map building tast. 8 kinds of experiment prototypes were built and usability test among 16 house wives was conducted for acquiring empirical data. As the experiment result, in terms of map building procedure, space-preferred procedure indicated better task performance than task-proffered procedure as we expected. For the LCD display installation factor, remote control with LCD display indicated higher task performance and subjective satisfaction. In robot navigation method, it was very difficult to find a significant difference between push type and pull type which contrary to our expectation. In fact, push type indicated higher subjective satisfaction. Also in feedback modality, we have acquired negative feedback an additional TTS operation guidance. It seems that robot's autonomy before achieving spatial information is rudiment condition which means users are just interacting with a mobile appliance. Thus they prefer remote-control-based interaction style in robot map building process as they used in traditional appliance control.

• The Korean Journal of Pesticide Science
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• v.20 no.4
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• pp.305-311
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• 2016

In cultivation environment, various pesticides are used and some of them could be volatilized into the air. This could affect farmer's health and also cause environmental pollution. This study was carried out to investigate the volatilization of pesticides, and use the reference data for preventing farmer's pesticide intoxication and securing worker safety. The experiment was conducted in a greenhouse using a lysimeter which was of $1m^2$ area and 1.5 m depth filled with upland soil. The pesticides treated in lysimeter soil were ethoprophos (5.0% GR), diazinon (34.0% EC), alachlor (43.7% EC), metolachlor (40.0% EC), chlorpyrifos (2.0% GR), pendimethalin (31.7% EC), carbaryl (50.0% WP), napropamide (50% WP), tebuconazole (25.0% WP) and imidacloprid (2.0% GR). Each pesticide was treated at a concentration of 770.5 mg based on A.I (%). The recovery of pesticide ranged from 77.4 to 99.3%. The volatilized pesticides in air were collected by personal air sampler with PUF tube at 4 l/min flow rate. In addition, temperature and humidity were measured. The collected samples were extracted using acetone in a soxhlet apparatus for 8 hours. The extracted pesticides were resoluted with acetonitrile and diluted 5 times. It was analyzed with LC-MS/MS. For 720 hours experiment, the largest vaporization amount of each pesticide in air was ethoprophos $15.24{\mu}g/m^3$, diazinon $5.14{\mu}g/m^3$, pendimethalin $2.70{\mu}g/m^3$, chlorpyrifos $1.76{\mu}g/m^3$, alachlor $1.40{\mu}g/m^3$, metolachlor $1.12{\mu}g/m^3$, carbaryl $0.27{\mu}g/m^3$, napropamide $0.22{\mu}g/m^3$, tebuconazole $0.11{\mu}g/m^3$ and imidacloprid $0.05{\mu}g/m^3$. The R value (coefficient of correlation) between volatilization and vapor pressure of pesticides is higher than 0.99. Therefore, there is high correlation between volatilization and vapor pressure of pesticides.