• 한국전산유체공학회:학술대회논문집
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• 1995.10a
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• pp.49-54
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• 1995

A numerical analysis on the effect of the front shape on the aerodynamic characteristics of HST model is made, using FVM based general purpose 3D Navier-Stokes eq. solver, TURBO-3D program. Numerical solutions are compared with each case of different front shape for HST model. The result shows a good quantitative aerodynamic characteristic tendencies for variation of front shape of HST. Thus it may be used as a basis in the design of the shape of real HST.

• 한국전산유체공학회:학술대회논문집
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• 2007.04a
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• pp.3-7
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• 2007

The characteristics of asymmetric vortex and side force of tangent-ogive-cylinder flight vehicle at high angles of attack have been performed by using upwind Navier-Stokes method with the ${\kappa}-{\omega}$ turbulence model. And Asymmetric transition positions are considered for generation of asymmetric vortex.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.420-423
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• 2003

A low temperature difference model Stirling engine is a small Stirling engine running with several degree of temperature difference without power output. In this study, the design parameters to give maximum power are discussed. As results, the phase angle is about 100 degree, and compression ratio is 1.5% of the ratio of heat source temperatures at maximum power condition.

• Communications for Statistical Applications and Methods
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• v.16 no.1
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• pp.163-168
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• 2009

Given the specific mean shift outlier model, the standard approaches to obtaining test statistics for outliers are discussed. Accuracy of outlier tests is investigated using subset curvatures. These subset curvatures appear to be reliable indicators of the adequacy of the linearization based test. Also, we consider obtaining graphical summaries of uncertainty in estimating parameters through confidence curves. The results are applied to the problem of assessing the accuracy of outlier tests.

• Journal of the Korean Statistical Society
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• v.20 no.1
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• pp.85-92
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• 1991

A set of conditions ensuring local asymptotic normality for independent but not necessarily identically distributed observations in semiparametric models is presented here. The conditions are turned out to be more direct and easier to verify than those of Oosterhoff and van Zwet(1979) in semiparametric models. Examples considered include the simple linear regression model and Cox's proportional hazards model without censoring where the covariates are not random.

• Journal of Acupuncture Research
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• v.22 no.2
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• pp.71-81
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• 2005

Objective : Dear antler (Cervus korean TEMMINCK var. mantchuricus Swinhoe) used for traditional immunosuppressive and immuno-activating action. The effect of deer antler herbal-acupuncture(DAH) solution, prepared by water extract method, on cathepsin activities in bone tissues (cartilage and synovial) cells from mouse rheumatoid arthritis (RA) model was studied. The cysteine endoprotease cathepsin mediates degradation of the MHC class II invariant chain (Ii) in human and mouse antigen-presenting cells. The studies described here examine the functional significance of cathepsin inhibition on autoantigen presentation and organ-specific autoimmune diseases in a murine model for RA. Methods : An animal model for RA in BALB/c mice thymectomized 3 days after birth (3d-Tx) was constructed All 3d-Tx BALB/c mice developed autoimmune lesions in the bone tissue cells, starting at 3 weeks of age, and the disease mediated by CD4+ T cells was chronic and progressive. Significant inhibitory effects of DAH solution on cathepsin S and L were observed in each organ in a dose-dependent manner. Moreover, we confirmed that cathepsin S and L activity in each organ were clearly inhibited by DAB solution. When we examined the inhibitory effects of DAH solution against autoantigen-specific T cell responses in vitro, in regional lymph node cells, but not in spleens, from model mice, a significant inhibitory effect of DAB solution was observed in a dose-dependent manner. DAH solution do not block T cell proliferation to Con A, indicated that the dose of DAB solution 10 to $20\;{\mu}g/m{\ell}$ was sufficient to inactivate the autoantigen-specific T cell responses in vitro. In vivo therapeutic effects of DAB solution were examined in a murine model for RA, autoantigen-specific (C-II-specific) T cell response were significantly inhibited in LNCs from DAH solution-treated mice. Results : Iinhibition of cathepsin S and L in vivo alters autoantigen presentation and development of organ-specific autoimmunity in RA model. Conclusion : These data identify selective inhibition of cysteine protease cathepsin S and L as a potential therapeutic strategy for autoimmune disease process such RA. Thus, DAH solution will served as a potent anti-inflammatory and anti-arthritic agents for treatment of human RA.

• Journal of Microbiology and Biotechnology
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• v.17 no.9
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• pp.1437-1444
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• 2007

A response surface model was developed for predicting the growth rates of Staphylococcus aureus in tryptic soy broth (TSB) medium as a function of combined effects of temperature, pH, and NaCl. The TSB containing six different concentrations of NaCl (0, 2, 4, 6, 8, and 10%) was adjusted to an initial of six different pH levels (pH 4, 5, 6, 7, 8, 9, and 10) and incubated at 10, 20, 30, and $40^{\circ}C$. In all experimental variables, the primary growth curves were well ($r^2=0.9000$ to 0.9975) fitted to a Gompertz equation to obtain growth rates. The secondary response surface model for natural logarithm transformations of growth rates as a function of combined effects of temperature, pH, and NaCl was obtained by SAS's general linear analysis. The predicted growth rates of the S. aureus were generally decreased by basic (pH 9-10) or acidic (pH 5-6) conditions and higher NaCl concentrations. The response surface model was identified as an appropriate secondary model for growth rates on the basis of correlation coefficient (r=0.9703), determination coefficient ($r^2=0.9415$), mean square error (MSE=0.0185), bias factor ($B_f=1.0216$), and accuracy factor ($A_f=1.2583$). Therefore, the developed secondary model proved reliable for predictions of the combined effect of temperature, NaCl, and pH on growth rates for S. aureus in TSB medium.

• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.315-320
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• 2009

A computational investigation is conducted on free convection from a thin plate having a surface heat source. The thermal configuration simulates the recently-proposed transparent film heater made of a single-walled carbon nanotube film on a glass substrate. The Navier-Stokes computations are carried out to study laminar free convection from the heater. Parallel numerical experiments are performed by using a simplified design analysis model which solve the conduction equation with the boundary conditions utilizing several existing correlations for convective heat transfer coefficient. Comparison leads to the most suitable boundary condition for the thermal model to evaluate the performance evaluation of a transparent thin-film heater.

• Asia pacific journal of information systems
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• v.15 no.4
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• pp.89-107
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• 2005

As new information technology(IT) adoption continues to produce many investment opportunities, imperfectly informed IT managers keep trying to acquire credible external signals to update their knowledge on new technologies. Such learning processes usually help them to reach better IT adoption decisions. In some cases, however, the opposite of the goal is achieved. Most IT managers quickly converge to the same adoption decision independent of their private information. Interestingly, such information cascade is the outcome of each individual decision maker's rational choice. A technology acceptance model(TAM) is adopted that has been widely used to predict the end-user's acceptance of a new technology. A model with individual charact-eristics and information cascade variables is constructed to explain user's intention in adopting blogging. The model is empirically tested with surveyed data. The results show that individual characteristics and information cascades have significant impacts in the case of blogging.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.36D no.2
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• pp.1-10
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• 1999

Direct extraction of FET's small signal model parameters needs predetermined parasitic elements usually obtained under forward cold FET conditionl This paper derives analytic intrinsic model for cold FET's and shows that normal cold FET condition can replace forward cold FET condition for extracting parasitic elements. Then, we track the error of hot FET's small signal model bounded by the cold FET condition and examine the validness of cold parasitic resistances by checking the existence of the error minimum.