• Title/Summary/Keyword: Key delivery

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Meeting the Energy Reduction Goal on a High Rise Building thru IPD Framework

  • Jeong, Pyung Oh;Lee, Peter;Kim, Sang-jin
    • International Journal of High-Rise Buildings
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    • v.2 no.2
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    • pp.93-96
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    • 2013
  • Greenhouse gas emissions and excessive energy consumption have been an on-going world issue nowadays. We can find that the majority portion is caused by high-rise office buildings. In order to resolve these problems, it is extremely important to implement various active or passive strategies in a building design. To successfully meet these design goals and energy reduction approaches, a project building must utilize an efficient design process from the early start. One of the most effective project delivery process called Integrated Project Delivery (IPD) will be implemented in a case study project building (KEPCO) during design phase and show how important it is to plan a project's green environmental performance goal together through an early collaboration from all key project participants, which helps to construct an successful green building design without any critical construction pitfalls.

Enhanced delivery of protein fused to cell penetrating peptides to mammalian cells

  • Moon, Jung-Il;Han, Min-Joon;Yu, Shin-Hye;Lee, Eun-Hye;Kim, Sang-Mi;Han, Kyuboem;Park, Chang-Hwan;Kim, Chun-Hyung
    • BMB Reports
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    • v.52 no.5
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    • pp.324-329
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    • 2019
  • Recent progress in cellular reprogramming technology and lineage-specific cell differentiation has provided great opportunities for translational research. Because virus-based gene delivery is not a practical reprogramming protocol, protein-based reprogramming has been receiving attention as a safe way to generate reprogrammed cells. However, the poor efficiency of the cellular uptake of reprogramming proteins is still a major obstacle. Here, we reported key factors which improve the cellular uptake of these proteins. Purified red fluorescent proteins fused with 9xLysine (dsRED-9K) as a cell penetrating peptide were efficiently delivered into the diverse primary cells. Protein delivery was improved by the addition of amodiaquine. Furthermore, purified dsRED-9K was able to penetrate all cell lineages derived from mouse embryonic stem cells efficiently. Our data may provide important insights into the design of protein-based reprogramming or differentiation protocols.

Analyzing Characteristics of Design-Build Delivery System in Korea Using System Dynamics Modeling (시스템다이내믹스 모델을 이용한 국내 설계시공 일괄입찰 발주방식 특성분석)

  • Lee, Hyun-Soo;Ji, Sae-Hyun;Park, Moon-Seo;Song, Sang-Hun
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.5
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    • pp.119-131
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    • 2007
  • Design build (DB) is a construction project delivery system which has become one of the favored ones and the growth of DB by the public agencies has been steadily increasing. DB can be viewed as an evolutionary project delivery system, since DB project team members collaborate on work with each other, keep seeking cost effective and innovative alternatives that meet the construction needs of the project. Thus DB outperformed others in delivery speed, cost saving, and turnover quality. In Korea, DB projects likewise have steadily increased that it is needed to analyze characteristics of DB delivery system in Korea. For that purpose, this research would offer an analysis of characteristics of DB delivery system in Korea using system dynamics model with investigating the public market trend, comparing DB performance to DBB, and analyzing questionnaire survey.

Survey on Nursing Care Delivery Systems of University Affiliated Hospitals in Korea (종합전문요양기관의 간호전달체계에 대한 실태조사 연구)

  • Kim, So Sun;Chae, Gye Soon;Kim, Kyeong Nam;Park, Kwang Ok;Moon, Seong Mi
    • Journal of Korean Clinical Nursing Research
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    • v.16 no.1
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    • pp.167-175
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    • 2010
  • Purpose: This study investigated nursing care delivery systems in 44 university affiliated hospitals and satisfactions with the systems perceived by 226 unit managers (head nurses) of general medical surgical wards. Methods: Data were collected with questionnaires consisting of checklists asking the unit managers their nursing care delivery systems and their satisfactions with the systems. Results: Four models of nursing care delivery systems (primary, modified primary, team, and functional models) were drawn from the participants' responses. Among the four key models 35% of the units adopted team model whereas 24.3% adopted primary model and 22.6% adopted modified primary model. In spite of 35% of team model being under use, 60.6% (n=137) of the unit managers answered the nursing delivery system of their units as team model and only 6.2% (n=14) answered their units having primary or modified primary models, instead of 46.9% combining both. In regard to the satisfaction, critical thinking ability of staff nurses (members in their units) was the most dissatisfactory area regardless of models of service delivery. Conclusion: Introducing team model supplemented with core concepts of primary model (primary team delivery model) into nursing practice will reform the workplace and therefore deliver safe health care services to patients.

The Effectiveness of Decision Support System for the Supplier Selection in e-Marketplace: A Case Study

  • Park Hae-Yeon;Lee Zoonky;Lim Sung-Il;Lee Sang-Goo
    • Management Science and Financial Engineering
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    • v.11 no.3
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    • pp.79-93
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    • 2005
  • Despite the fact that the sourcing process in B2B e-Marketplaces is one of the most important tasks, the evaluation and selection process of suppliers have been ad-hoc based and mainly dependent on the experience of sourcing managers' subjective knowledge. To remedy the problem, we developed a decision support System (called Wise - I) that helps sourcing managers evaluate suppliers in a more systematic way. The system reflects company's strategy and know-how by adopting company enforced weighted scores for different factors and employing a more scientific method of considering factors other than price and on-time delivery rate, utilizing the AHP method. This paper reports the effectiveness of the system as well as the detailed description of the system. To investigate the effectiveness of the system, we collected information through interview and questionnaire survey. The information was also augmented through the firm key index system, which monitors average delivery lead time and on-time delivery rate. The result indicates that the system leads to the efficiency of purchasing section and the transparency of buying process, therefore reduces delivery time and cost.

Stereo Video Delivery System for Enhanced Immersion (실감성 증진을 위한 스테레오 비디오 전송 시스템)

  • 장혜영;오세찬;김종원;우운택;변옥환
    • Journal of KIISE:Computing Practices and Letters
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    • v.9 no.6
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    • pp.602-609
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    • 2003
  • Emerging high-speed next-generation Internet is enabling immersive media communication systems and applications to realize geographically distributed team collaborations while overcoming the limit of distance and time. Focusing on the reliable real-time delivery of 3D (i.e., stereo) video among corresponding parties, in this paper, key schemes for stereo video processing/display and reliable transport of stereo video packets over high-speed Internet are designed and implemented. The performance of proposed stereo video delivery system is evaluated both by emulating various network situations for quantitative comparison and by transmitting over real-world Internet up to the speed of around 100 Mbps. The results demonstrate the feasibility of the proposed system in supporting the desired immersive communication.

Group Key Management based on (2, 2) Secret Sharing

  • Wuu, Lih-Chyau;Hung, Chi-Hsiang;Kuo, Wen-Chung
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.3
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    • pp.1144-1156
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    • 2014
  • In Internet, IP multicast has been used successfully to provide an efficient, best-effort delivery service for group communication applications. However, applications such as multiparty private conference, distribution of stock market information, pay per view and other subscriber services may require secure multicast to protect integrity and confidentiality of the group traffic, and validate message authenticity. Providing secure multicast for group communication is problematic without a robust group key management. In this paper, we propose a group key management scheme based on the secret sharing technology to require each member by itself to generate the group key when receiving a rekeying message multicast by the group key distributor. The proposed scheme enforces mutual authentication between a member and the group key distributor while executing the rekeying process, and provides forward secrecy and backward secrecy properties, and resists replay attack, impersonating attack, group key disclosing attack and malicious insider attack.

Methods on improvements of the poor oral bioavailability of ginsenosides: Pre-processing, structural modification, drug combination, and micro- or nano- delivery system

  • Qi-rui Hu;Huan Hong;Zhi-hong Zhang;Hua Feng;Ting Luo;Jing Li;Ze-yuan Deng;Fang Chen
    • Journal of Ginseng Research
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    • v.47 no.6
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    • pp.694-705
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    • 2023
  • Panax ginseng Meyer is a traditional Chinese medicine that is widely used as tonic in Asia. The main pharmacologically active components of ginseng are the dammarane-type ginsenosides, which have been shown to have anti-cancer, anti-inflammatory, immunoregulatory, neuroprotective, and metabolic regulatory activities. Moreover, some of ginsenosides (eg, Rh2 and Rg3) have been developed into nutraceuticals. However, the utilization of ginsenosides in clinic is restrictive due to poor permeability in cells and low bioavailability in human body. Obviously, the dammarane skeleton and glycosyls of ginsenosides are responsible for these limitations. Therefore, improving the oral bioavailability of ginsenosides has become a pressing issue. Here, based on the structures of ginsenosides, we summarized the understanding of the factors affecting the oral bioavailability of ginsenosides, introduced the methods to enhance the oral bioavailability and proposed the future perspectives on improving the oral bioavailability of ginsenosides.

Designing the Optimal Urban Distribution Network using GIS : Case of Milk Industry in Ulaanbaatar Mongolia (GIS를 이용한 최적 도심 유통 네트워크 설계 : 몽골 울란바타르 내 우유 산업 사례)

  • Enkhtuya, Daariimaa;Shin, KwangSup
    • The Journal of Bigdata
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    • v.4 no.2
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    • pp.159-173
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    • 2019
  • Last-Mile delivery optimization plays a key role in the urban supply chain operation, which is the most expensive and time-consuming and most complicated part of the whole delivery process. The urban consolidation center (UCC) is regarded as a significant asset for supporting customer demand in the last-mile delivery service. It is the key benefit of UCC to improve the load balance of vehicles and to reduce the total traveling distance by finding the better route with the well-organized multi-leg vehicle journey in the urban area. This paper presents the model using multiple scenario analysis integrated with mathematical optimization techniques using Geographic Information System (GIS). The model aims to find the best solution for the distribution network consisted of DC and UCC, which is applied to the case of Ulaanbaatar Mongolia. The proposed methodology integrates two sub-models, location-allocation model and vehicle routing problem. The multiple scenarios devised by selecting locations of UCC are compared considering the general performance and delivery patterns together. It has been adopted to make better decisions the quantitative metrics such as the economic value of capital cost, operating cost, and balance of using available resources. The result of this research may help the manager or public authorities who should design the distribution network for the last mile delivery service optimization using UCC within the urban area.

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Key Management Scheme for Providing the Confidentiality in Mobile Multicast (이동 멀티캐스트에서 기밀성을 제공하기 위한 키관리 방법)

  • Roh Jong-Hyuk;Jin Seung-Hun;Lee Kyoon-Ha
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.16 no.1
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    • pp.97-104
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    • 2006
  • For successfully deploying many multicast service in the mobile environment, security infrastructures must be developed that manage the keys needed to provide access control to content. In this paper, we propose two methods for designing the key management scheme for the mobile multicast environment. The proposed schemes match the key management tree to the mobile multicast environment for localizing the delivery of he rekeying messages, reducing the communication costs, and solving the handoff problem in wireless region.