• Membrane and Water Treatment
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• 제7권4호
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• pp.341-353
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• 2016

Papermaking reconstituted tobacco is an important strategy for recycling the waste tobacco residues. To indentify the influences of the inorganic components on harmful components delivery in cigarette smoke, a self-made electrodialysis stack was assembled to desalt the tobacco extract. The influences of the applied current and extract content on the removal rate of the inorganic ions were investigated. Results indicated that the applied current was a dominant impact on the desalination performance. High currents lower than the limiting current density could accelerate the desalting efficiency but cause higher energy consumption. A current of 2 A, or current density of ${\sim}11mA{\cdot}cm^{-2}$, was an optimal choice by considering both the energy consumption and desalting efficiency. A 20% tobacco extract was an appropriate content for the electrodialysis process. More than 90% of inorganic ions could be removed under the optimum condition. The preliminary result indicated that removal of inorganic components was beneficial to decrease the harmful component delivery in cigarette smoke. Naturally, ED is an environmentally friendly and high-effective technology for desalting the tobacco extract.

• 한국전자거래학회지
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• 제10권2호
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• pp.89-108
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• 2005

SOAP 표준 규약은 보안에 대한 특별한 언급을 하지 않고 있으며 이는 정보보호의 측면에서 상당한 위험 요소를 안고 있다. 특히 사용자 인증 시 SOAP Header내의 Username과 Password Element로 텍스트 값을 전송하게 되면 악의를 가진 자에게 스니핑(Sniffing) 및 재연(Replay) 공격을 받게 될 가능성이 있다. 본 논문에서는 SOAP 메시지의 인증 정보에 대한 여러 공격들을 효율적으로 대응할 수 있는 새로운 사용자 인증 메커니즘을 제시한다. 제안한 메커니즘은 S/KEY 시스템의 단점을 보완하여 사용횟수의 제한이 없으며 초기화 과정을 여러 번 수행할 필요가 없다. 또한 오버헤드에 대한 부담이 없으며 seed의 노출에 대한 위험 부담도 상대적으로 적다. 제안한 메커니즘은 SOAP 메시지의 사용자 인증을 보다 효율적이고 안전하게 제공한다.

• Archives of Pharmacal Research
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• 제26권11호
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• pp.892-897
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• 2003

Anticancer drugs have serious side effects arising from their poor malignant cells selectivity, Since insulin receptors highly express on the cytomembrane of some kind of tumor cells, using insulin as the vector was expected to reduce serious side effects of the drugs. The objective of this study was to evaluate the tumor targeting effect of the newly synthesized mitoxantrone-insulin conjugate (MIT-INS) with the drug loading of 11.68%. In vitro stability trials showed MIT-INS were stable in buffers with different pH (2-8) at $37^{\circ}C$ within 120 h (less than 3% of free MIT released), and were also stable in mouse plasma within 48 h (less than 1 % of free MIT released). In vivo study on tumor-bearing mice showed that, compared with MIT [75.92 $\mu g \cdot$ h/g of the area under the concentration-time curve (AUC) and 86.85 h of mean residence time (MRT)], the conjugates had better tumor-targeting efficiency with enhanced tumor AUC of 126.53 1l9 h/g and MTR of 151.95 h. The conjugate had much lower toxicity to most other tissues with targeting indexes ($TI^c$) no larger than 0.3 besides good tumor targeting efficiency with $TI^c$ of 1.67. The results suggest the feasibility to promote the curative effect in ca.ncer chemotherapy by using insulin as the vector of anti-cancer drugs.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권11호
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• pp.4268-4290
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• 2015

Future mobile communications face enormous challenges as traditional voice services are replaced with increasing mobile multimedia and data services. To address the vast data traffic volume and the requirement of user Quality of Experience (QoE) in the next generation mobile networks, it is imperative to develop efficient content distribution technique, aiming at significantly reducing redundant data transmissions and improving content delivery performance. On the other hand, in recent years cloud computing as a promising new content-centric paradigm is exploited to fulfil the multimedia requirements by provisioning data and computing resources on demand. In this paper, we propose a cooperative caching framework which implements State based Content Distribution (SCD) algorithm for future mobile networks. In our proposed framework, cloud service providers deploy a plurality of cloudlets in the network forming a Distributed Cloud Service Network (DCSN), and pre-allocate content services in local cloudlets to avoid redundant content transmissions. We use content popularity and content state which is determined by content requests, editorial updates and new arrivals to formulate a content distribution optimization model. Data contents are deployed in local cloudlets according to the optimal solution to achieve the lowest average content delivery latency. We use simulation experiments to validate the effectiveness of our proposed framework. Numerical results show that the proposed framework can significantly improve content cache hit rate, reduce content delivery latency and outbound traffic volume in comparison with known existing caching strategies.

• Journal of Ginseng Research
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• 제40권3호
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• pp.269-277
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• 2016

Background: The findings of currently available studies are not consistent with regard to the association between the risk of cancer and ginseng consumption. Therefore, we aimed to evaluate this association by conducting a meta-analysis of different studies. Methods: To systematically evaluate the effect of ginseng consumption on cancer incidence, six databases were searched, including PubMed, Ovid Technologies, Embase, The Cochrane Library, China National Knowledge Infrastructure, and Chinese VIP Information, from 1990 to 2014. Statistical analyses based on the protocol employed for a systematic review were conducted to calculate the summary relative risks (RRs) and 95% confidence intervals (CIs). Results: We identified nine studies, including five cohort studies, three case-control studies, and one randomized controlled trial, evaluating the association between ginseng consumption and cancer risk; these studies involved 7,436 cases and 334,544 participants. The data from the meta-analysis indicated a significant 16% lower risk of developing cancer in patients who consumed ginseng (RR = 0.84, 95% CI = 0.76-0.92), with evidence of heterogeneity (p = 0.0007, $I^2$ = 70%). Stratified analyses suggested that the significant heterogeneity may result from the incidence data for gastric cancer that were included in this study. Publication bias also showed the same result as the stratified analyses. In addition, subgroup analyses for four specific types of cancer (colorectal cancer, lung cancer, gastric cancer, and liver cancer) were also performed. The summary RRs for ginseng intake versus no ginseng consumption were 0.77 for lung cancer, 0.83 for gastric cancer, 0.81 for liver cancer, and 0.77 for colorectal cancer. Conclusion: The findings of this meta-analysis indicated that ginseng consumption is associated with a significantly decreased risk of cancer and that the effect is not organ specific.

• 대한임상독성학회지
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• 제16권2호
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• pp.131-140
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• 2018

Purpose: The National Emergency Medical Center has been running a project for the storage and delivery of antidotes for acute poisoning patients of the Department of Health and Welfare, Korea. This study analyzed the results of this project over the past two years. Methods: The requests received by the National Emergency Medical Center and the data on the delivery process were analyzed. Results: This study analyzed a total of 121 patients with acute poisoning, who were requested to receive an antidote reserved at 20 key hospitals in 2015-2017, and whose age was $52.3{\pm}23.5\;years$; old; 54 were women. Intentional poisoning were 58.7%, and the home was the most common place of exposure (66.9%). The toxic substances were chemicals (32.2%), pesticides (27.3%), medicines (24.8%), and snake venom (4.1%). The patient's poison severity score was $2.4{\pm}0.7$ (median 3) indicating moderate-to-severe toxicity. Antidote administration was the cases treated in key hospitals 67.8% (82/121), in which transferred patients accounted for 57.3% (47/82). After receiving an antidote request from a hospital other than the key hospitals, the median was 75.5 minutes (range 10 to 242 minutes) until the antidote reached the patient, and an average of 81.5 minutes was required. The results of emergency care were intensive care unit (70.3%), general wards (13.2%), death (10.7%), and discharge from emergency department (5.0%). Conclusion: This study showed that the characteristics of acute poisoning patients treated with an antidote were different from previous reports of poisoned patients in the emergency department, and basic data on the time required for delivery from key hospitals was different.

• 디지털융복합연구
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• 제11권3호
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• pp.181-187
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• 2013

공급자와 소비자간의 정보공유는 기능 중심에서 프로세스 중심이 되면서, 유연성과 고객 서비스를 극대화하기 위한 새로운 물류 개념을 요구하게 되었다. 다시 말하면 원부자재의 조달에서부터 생산을 거쳐 고객에게 판매되기까지의 전 과정에 걸친 개체간의 수요와 공급의 사슬관계를 의미하는 공급망 내에서 정보, 자금 그리고 물의 흐름을 관리 통제하는 공급사슬경영(SCM)이 사업의 핵심역량으로 인식되고 있다. 또한 국내 기업들의 수 배송 업무의 합리화는 국내 기업 물류관리의 가장 중요한 과제중의 하나로 부각되고 있다. 물류센터로부터 각 거래처로 물품을 배달하는 배송업무의 경우에는 기업의 물류정보시스템이 상류 중심의 데이터 체계로 구축되어왔기 때문에 물류관리 업무의 합리화에 활용할 수 있는 기초 데이터 부재와 현실적인 제약조건들을 고려한 효율적인 자동배차 알고리듬을 적용하지 못했기 때문에 배차담당자들의 수작업 조정시간이 장시간 소요되었다. 따라서 본 논문에서는 현실적인 다양한 제약조건을 만족하고, 수작업 조정시간이 대폭 줄이면서, 우편중심 좌표를 이용한 차량별 근거리 그룹핑으로 자동배차 지원시스템의 휴리스틱 알고리듬을 설계하도록 한다.

• Journal of information and communication convergence engineering
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• 제22권2호
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• pp.121-126
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• 2024

In enterprise environments, file owners are often required to share critical files with other users, with encryption-based file delivery systems used to maintain confidentiality. However, important information might be leaked if the cryptokey used for encryption is exposed. To recover confidentiality, the file owner must then re-encrypt and redistribute the file along with its new encryption key, which requires considerable resources. To address this, we propose a key management server that minimizes the distribution of encryption keys when critical files are compromised, with unique encryption keys assigned for each registered user to access critical files. While providing the targeted functions, the server employs a level of system resources comparable to that of legacy digital rights management. Thus, when implemented in an enterprise environment, the proposed server minimizes cryptokey redistribution while maintaining accessibility to critical files in the event of an information breach.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2012년도 추계 학술논문 발표대회
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• pp.233-235
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• 2012

Continually having growed up overseas construction market for new Nuclear Power Plant(NPP), the exports of Korean Reactor emerges as the key task of National Nuclear Business. The objective of this study is to strengthen the competitiveness of Korean Reactor through the improvement of Construction Project Contract & Delivery System for NPP. This study suggests the method for increasing Korean Reactor's competitiveness of exports by analyzing the business environment of foreign market and comparing Contract & Delivery System between domestic and foreign.

• 한국산업정보학회논문지
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• 제16권2호
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• pp.39-47
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• 2011

Adapting content services to the needs of the users requires content adaptation for context and sensibility. Adapting to context may necessitate distinguishing between video delivery to a PC versus a smart phone, while adapting to sensibility may necessitate between video delivery outside, in a quiet environment, or at home, or offering different movie choices on a sunny summer day, a cold winter day or a holiday season. One key area to address in providing adaptive content services is the design of the delivery system architecture of the adaptive content server. This paper describes several alternatives for this architecture, and outlines some additional concerns that must be considered when the chosen architecture is implemented.