• Membrane and Water Treatment
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• v.7 no.4
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• pp.341-353
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• 2016

Papermaking reconstituted tobacco is an important strategy for recycling the waste tobacco residues. To indentify the influences of the inorganic components on harmful components delivery in cigarette smoke, a self-made electrodialysis stack was assembled to desalt the tobacco extract. The influences of the applied current and extract content on the removal rate of the inorganic ions were investigated. Results indicated that the applied current was a dominant impact on the desalination performance. High currents lower than the limiting current density could accelerate the desalting efficiency but cause higher energy consumption. A current of 2 A, or current density of ${\sim}11mA{\cdot}cm^{-2}$, was an optimal choice by considering both the energy consumption and desalting efficiency. A 20% tobacco extract was an appropriate content for the electrodialysis process. More than 90% of inorganic ions could be removed under the optimum condition. The preliminary result indicated that removal of inorganic components was beneficial to decrease the harmful component delivery in cigarette smoke. Naturally, ED is an environmentally friendly and high-effective technology for desalting the tobacco extract.

• The Journal of Society for e-Business Studies
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• v.10 no.2
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• pp.89-108
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• 2005

The SOAP specifications are not provided a functions of information security, especially authentication function. In case of user authentication, delivery of the username and password elements can be exposed to sniffing/replay attack by malicious attacker. In this paper, we propose a new mechanism to protect authentication attacks for the SOAP messages. The proposed mechanism is compensated for weakness of S/KEY system. Our mechanism has no limitation for time and overhead and also provide a more effective and secure delivery.

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.892-897
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• 2003

Anticancer drugs have serious side effects arising from their poor malignant cells selectivity, Since insulin receptors highly express on the cytomembrane of some kind of tumor cells, using insulin as the vector was expected to reduce serious side effects of the drugs. The objective of this study was to evaluate the tumor targeting effect of the newly synthesized mitoxantrone-insulin conjugate (MIT-INS) with the drug loading of 11.68%. In vitro stability trials showed MIT-INS were stable in buffers with different pH (2-8) at $37^{\circ}C$ within 120 h (less than 3% of free MIT released), and were also stable in mouse plasma within 48 h (less than 1 % of free MIT released). In vivo study on tumor-bearing mice showed that, compared with MIT [75.92 $\mu g \cdot$ h/g of the area under the concentration-time curve (AUC) and 86.85 h of mean residence time (MRT)], the conjugates had better tumor-targeting efficiency with enhanced tumor AUC of 126.53 1l9 h/g and MTR of 151.95 h. The conjugate had much lower toxicity to most other tissues with targeting indexes ($TI^c$) no larger than 0.3 besides good tumor targeting efficiency with $TI^c$ of 1.67. The results suggest the feasibility to promote the curative effect in ca.ncer chemotherapy by using insulin as the vector of anti-cancer drugs.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.11
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• pp.4268-4290
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• 2015

Future mobile communications face enormous challenges as traditional voice services are replaced with increasing mobile multimedia and data services. To address the vast data traffic volume and the requirement of user Quality of Experience (QoE) in the next generation mobile networks, it is imperative to develop efficient content distribution technique, aiming at significantly reducing redundant data transmissions and improving content delivery performance. On the other hand, in recent years cloud computing as a promising new content-centric paradigm is exploited to fulfil the multimedia requirements by provisioning data and computing resources on demand. In this paper, we propose a cooperative caching framework which implements State based Content Distribution (SCD) algorithm for future mobile networks. In our proposed framework, cloud service providers deploy a plurality of cloudlets in the network forming a Distributed Cloud Service Network (DCSN), and pre-allocate content services in local cloudlets to avoid redundant content transmissions. We use content popularity and content state which is determined by content requests, editorial updates and new arrivals to formulate a content distribution optimization model. Data contents are deployed in local cloudlets according to the optimal solution to achieve the lowest average content delivery latency. We use simulation experiments to validate the effectiveness of our proposed framework. Numerical results show that the proposed framework can significantly improve content cache hit rate, reduce content delivery latency and outbound traffic volume in comparison with known existing caching strategies.

• Journal of Ginseng Research
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• v.40 no.3
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• pp.269-277
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• 2016

Background: The findings of currently available studies are not consistent with regard to the association between the risk of cancer and ginseng consumption. Therefore, we aimed to evaluate this association by conducting a meta-analysis of different studies. Methods: To systematically evaluate the effect of ginseng consumption on cancer incidence, six databases were searched, including PubMed, Ovid Technologies, Embase, The Cochrane Library, China National Knowledge Infrastructure, and Chinese VIP Information, from 1990 to 2014. Statistical analyses based on the protocol employed for a systematic review were conducted to calculate the summary relative risks (RRs) and 95% confidence intervals (CIs). Results: We identified nine studies, including five cohort studies, three case-control studies, and one randomized controlled trial, evaluating the association between ginseng consumption and cancer risk; these studies involved 7,436 cases and 334,544 participants. The data from the meta-analysis indicated a significant 16% lower risk of developing cancer in patients who consumed ginseng (RR = 0.84, 95% CI = 0.76-0.92), with evidence of heterogeneity (p = 0.0007, $I^2$ = 70%). Stratified analyses suggested that the significant heterogeneity may result from the incidence data for gastric cancer that were included in this study. Publication bias also showed the same result as the stratified analyses. In addition, subgroup analyses for four specific types of cancer (colorectal cancer, lung cancer, gastric cancer, and liver cancer) were also performed. The summary RRs for ginseng intake versus no ginseng consumption were 0.77 for lung cancer, 0.83 for gastric cancer, 0.81 for liver cancer, and 0.77 for colorectal cancer. Conclusion: The findings of this meta-analysis indicated that ginseng consumption is associated with a significantly decreased risk of cancer and that the effect is not organ specific.

• Journal of The Korean Society of Clinical Toxicology
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• v.16 no.2
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• pp.131-140
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• 2018

Purpose: The National Emergency Medical Center has been running a project for the storage and delivery of antidotes for acute poisoning patients of the Department of Health and Welfare, Korea. This study analyzed the results of this project over the past two years. Methods: The requests received by the National Emergency Medical Center and the data on the delivery process were analyzed. Results: This study analyzed a total of 121 patients with acute poisoning, who were requested to receive an antidote reserved at 20 key hospitals in 2015-2017, and whose age was $52.3{\pm}23.5\;years$; old; 54 were women. Intentional poisoning were 58.7%, and the home was the most common place of exposure (66.9%). The toxic substances were chemicals (32.2%), pesticides (27.3%), medicines (24.8%), and snake venom (4.1%). The patient's poison severity score was $2.4{\pm}0.7$ (median 3) indicating moderate-to-severe toxicity. Antidote administration was the cases treated in key hospitals 67.8% (82/121), in which transferred patients accounted for 57.3% (47/82). After receiving an antidote request from a hospital other than the key hospitals, the median was 75.5 minutes (range 10 to 242 minutes) until the antidote reached the patient, and an average of 81.5 minutes was required. The results of emergency care were intensive care unit (70.3%), general wards (13.2%), death (10.7%), and discharge from emergency department (5.0%). Conclusion: This study showed that the characteristics of acute poisoning patients treated with an antidote were different from previous reports of poisoned patients in the emergency department, and basic data on the time required for delivery from key hospitals was different.

• Journal of Digital Convergence
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• v.11 no.3
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• pp.181-187
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• 2013

Moreover a new logistics concept is needed through the sharing information between suppliers and consumers, which maximizes the level of customers service and its flexibility by changing functional-oriented to process-oriented. In other words, Supply Chain Management(SCM) is now considered as a key aspect of business, which controls the flows of information, funds, and goods in the supply chain. Rationalization of transport-delivery system will be one of the most important issues on logistics management to the domestic companies. The companies need the effective delivery system. Especially in the case of delivery system from distribution centers to customers or vendors, it might take a long time to control the delivery system manually because it would be hard to apply the automatic vehicle routing algorithm effectively considering all the practical constraints. Thus this study develops a heuristic algorithm of automatic vehicle delivery support system in terms of grouping by short ranges of vehicle movement utilizing postal coordinates, which satisfies a variety of realistic constraints and reduces controlling time of manual operations.

• Journal of information and communication convergence engineering
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• v.22 no.2
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• pp.121-126
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• 2024

In enterprise environments, file owners are often required to share critical files with other users, with encryption-based file delivery systems used to maintain confidentiality. However, important information might be leaked if the cryptokey used for encryption is exposed. To recover confidentiality, the file owner must then re-encrypt and redistribute the file along with its new encryption key, which requires considerable resources. To address this, we propose a key management server that minimizes the distribution of encryption keys when critical files are compromised, with unique encryption keys assigned for each registered user to access critical files. While providing the targeted functions, the server employs a level of system resources comparable to that of legacy digital rights management. Thus, when implemented in an enterprise environment, the proposed server minimizes cryptokey redistribution while maintaining accessibility to critical files in the event of an information breach.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2012.11a
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• pp.233-235
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• 2012

Continually having growed up overseas construction market for new Nuclear Power Plant(NPP), the exports of Korean Reactor emerges as the key task of National Nuclear Business. The objective of this study is to strengthen the competitiveness of Korean Reactor through the improvement of Construction Project Contract & Delivery System for NPP. This study suggests the method for increasing Korean Reactor's competitiveness of exports by analyzing the business environment of foreign market and comparing Contract & Delivery System between domestic and foreign.

• Journal of Korea Society of Industrial Information Systems
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• v.16 no.2
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• pp.39-47
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• 2011

Adapting content services to the needs of the users requires content adaptation for context and sensibility. Adapting to context may necessitate distinguishing between video delivery to a PC versus a smart phone, while adapting to sensibility may necessitate between video delivery outside, in a quiet environment, or at home, or offering different movie choices on a sunny summer day, a cold winter day or a holiday season. One key area to address in providing adaptive content services is the design of the delivery system architecture of the adaptive content server. This paper describes several alternatives for this architecture, and outlines some additional concerns that must be considered when the chosen architecture is implemented.