• 한국발생생물학회지:발생과생식
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• 제23권1호
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• pp.63-72
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• 2019

The head gap gene buttonhead (btd) is required for the patterning of head segments in the early Drosophila embryo. Mutant phenotypes of btd display a gap-like phenotype in which antennal, intercalary, mandibular and the anterior portion of the maxillary segments are eliminated. In agreement with the phenotypes, btd is expressed in a stripe covering the head segments at the blastoderm stage. During the early phase of the germband extension, btd is expressed in stripes with single segmental periodicity, which is required for the formation of the peripheral nervous system. In contrast to the key role of btd in Drosophila embryonic development, it has been suggested that Tribolium ortholog of btd (Tc-btd) is dispensable for embryonic head development. In order for better understanding of the requirement of Tc-btd in the early Tribolium embryo, we re-analyzed the expression patterns and functions of Tc-btd during embryonic segmentation. Tc-btd is expressed in segmental stripes at the stages of blastoderm and germband elongation. Up to 28.3% of embryos in which Tc-btd is knocked down displays the loss of antennal, mandibular and the pregnathal regions in the head, with abdominal segments being disrupted in the trunk. Our findings suggest that Tc-btd is required for the head and trunk development in the early Tribolium embryo.

• 한국동물위생학회지
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• 제44권3호
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• pp.163-168
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• 2021

The rapid and reliable detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a key role in isolating infected patients and preventing further viral transmission. In this study, we evaluated the clinical diagnostic performances of a commercial real-time reverse transcription loop-mediated isothermal amplification (RRT-LAMP) assay (Isopollo^® COVID-2 assay, M-monitor, Daegu, Korea) using eighty COVID-19 suspected clinical samples and compared these with the results of a commercial real-time reverse transcription polymerase chain reaction (RT-qPCR) assay (Allplex^TM 2019-nCoV rRT-QPCR Assay, SeeGene, Seoul, Korea). The results of the RRT-LAMP assay targeting the N or RdRp gene of SARS-CoV-2 showed perfect agreement with the RT-qPCR assay results in terms of detection. Furthermore, the RRT-LAMP assay was completed in just within a 20-min reaction time, which is significantly faster than about the 2 h currently required for the RT-qPCR assay, thus enabling prompt decision making regarding the isolation of infected patients. The RRT-LAMP assay will be a valuable tool for rapid, sensitive, and specific detection of SARS-CoV-2 in human or unexpected animal clinical cases.

• Journal of Korea Trade
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• 제23권4호
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• pp.80-102
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• 2019

Purpose - This paper aims to articulate relationship about factors influencing FTA utilization by dividing them into company's external and internal factors and performing investigation on the relationship between FTA utilization and export performance. Design/methodology - This study verified factors influencing FTA utilization by dividing them into company's external and internal factors and performing investigation on the relationship between FTA utilization and export performance. Empirical analysis was performed by setting internal and external factors required for FTA utilization as variables. To achieve this, research model was established based on previous study, hypothesis was deduced, and statistical program were used to test the hypothesis. This study performed empirical analysis using statistical program of SPSS 18.0 and AMOS 18.0 for the research model. Findings - Empirical analysis was performed regarding the effect of the FTA utilization on export performance and previous study defined export performance as the company's increased economy benefits through export and increase in new transactions. Analysis was also performed for factors affecting the FTA utilization by the company and through management and response of external factors and internal factors it was confirmed that the FTA utilization by the company led to increase in the company's export performance as a result. This study proposes a method to achieve export performance based on this. Originality/value - Companies seeking to utilize the FTA sign the Contract for the International Sale of goods and there are many conditions to meet in order to receive trade preferences during the transaction process. Existing trade order and order in the FTA have to be followed. Country of origin can be seen as key in the FTA. The Rule of Origin becomes the most important evaluation standard in applying preferential tariff in the FTA. Such regulations can be seen as external factors which cannot be controlled by the company. Internal factors are capabilities owned before that can be controlled by the company. The study sought to test the variables regarding factors centered on such capability. This study verified factors influencing FTA utilization by dividing them into company's external and internal factors and performing investigation on the relationship between FTA utilization and export performance.

• 융합보안논문지
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• 제19권1호
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• pp.3-10
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• 2019

5G 네트워크는 초고속, 초연결, 초저지연이라는 요구를 구현하기 위해 다양한 ICT 기술들을 접목한 차세대 융합 네트워크로서, 이전 세대 이동통신 네트워크의 보안취약점을 해결하기 위해 다양한 노력들이 시도되었다. 그러나 현재까지 발표된 표준화 규격들에는 USIM 탈취 및 복제, 메시지 재전송 공격, 경쟁조건 공격 등의 보안취약점이 여전히 존재한다. 이러한 문제를 해결하기 위해, 본 논문에서는 물리적 복제방지 기능인 PUF 기술을 적용한 새로운 5G 인증 및 키합의 프로토콜을 제시한다. 제시된 PUF 기반의 인증 및 키합의 프로토콜은 특정 입력값에 대해 장치별로 고유하게 생성되는 응답값과 해시함수를 이용하여 현재까지 식별된 보안취약점을 개선한다. 이러한 접근 방법은 보안성이 중요하게 요구되는 영역에서 5G 네트워크를 활용할 경우, 저렴한 PUF 회로의 추가를 통해 강력한 화이트리스트 정책을 구현할 수 있게 해 준다. 또한 기존 프로토콜에 추가적인 암호 알고리즘을 적용하지 않기 때문에 연산 비용 증가나 인증 파라미터 저장 공간 증가의 부담도 상대적으로 적다.

• Computers and Concrete
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• 제23권1호
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• pp.61-68
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• 2019

This paper presents a computational rational model to predict the ultimate and optimized load capacity of reinforced concrete (RC) beams strengthened by a combination of longitudinal and transverse fiber reinforced polymer (FRP) composite plates/sheets (flexure and shear strengthening system). Several experimental and analytical studies on the confinement effect and failure mechanisms of fiber reinforced polymer (FRP) wrapped columns have been conducted over recent years. Although typical axial members are large-scale square/rectangular reinforced concrete (RC) columns in practice, the majority of such studies have concentrated on the behavior of small-scale circular concrete specimens. A high performance concrete, known as polymer concrete, made up of natural aggregates and an orthophthalic polyester binder, reinforced with non-metallic bars (glass reinforced polymer) has been studied. The material is described at micro and macro level, presenting the key physical and mechanical properties using different experimental techniques. Furthermore, a full description of non-metallic bars is presented to evaluate its structural expectancies, embedded in the polymer concrete matrix. In this paper, the mechanism of mechanical interaction of smooth and lugged FRP rods with concrete is presented. A general modeling and application of various elements are demonstrated. The contact parameters are defined and the procedures of calculation and evaluation of contact parameters are introduced. The method of calibration of the calculated parameters is presented. Finally, the numerical results are obtained for different bond parameters which show a good agreement with experimental results reported in literature.

• Journal of Ginseng Research
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• 제45권1호
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• pp.156-162
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• 2021

Background: It is estimated that 20-30% of ginseng crops in Canada are lost to root rot each harvest. This disease is commonly caused by fungal infection with Ilyonectria, previously known as Cylindrocarpon. Previous reports have linked the virulence of fungal disease to the production of siderophores, a class of small-molecule iron chelators. However, these siderophores have not been identified in Ilyonectria. Methods: High-resolution LC-MS/MS was used to screen Ilyonectria and Cylindrocarpon strain extracts for secondary metabolite production. These strains were also tested for their ability to cause root rot in American ginseng and categorized as virulent or avirulent. The differences in detected metabolites between the virulent and avirulent strains were compared with a focus on siderophores. Results: For the first time, a siderophore N,N',N"-triacetylfusarinine C (TAFC) has been identified in Ilyonectria, and it appears to be linked to disease virulence. Siderophore production was suppressed as the concentration of iron increased, which is in agreement with previous reports. Conclusion: The identification of the siderophore produced by Ilyonectria gives us further insight into the root rot disease that heavily affects ginseng crop yields. This research identifies a molecular pathway previously unknown for ginseng root rot and could lead to new disease treatment options.

• 한국병원경영학회지
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• 제26권2호
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• pp.43-55
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• 2021

Purposes: In this study, we examined the factors which silenced the organizing members and how the factors affects deprivation of employment about the organization culture, the organizational silence, and the turnover intention. Methodology: In order to research, we carry out a survey on 400 employees of small and medium hospitals. Among them, 321 questionnaires were used for actual analysis, excluding insincere respondents, non-responders or duplicate respondents. In order to verify the hypotheses in this study, we conduct the covariance Structural Equation Model(SEM). Finding: We obtained results using following hypotheses. First, ''The organization culture has an effect on the turnover intention.'' Second, ''The organization culture has an effect on the organizational silence'' Third, ''The organizational silence has a influence on the turnover intention.'' Finally, ''When the organization culture mediates the organizational silence, the adaptation relationship of the ornization effectiveness is different.'', as the key hypothesis, showed that the agreement culture, rational culture, and hierarchical culture of the organization culture type were statistically significant. The organizational silence as a parameter has the partial mediating effects(-) because it has direct and indirect effects. Practical Implications: The results of this study showed that the reason for the organizational silence of the organizing members is that the organization culture by a grade of rank is the largest and these the organizational silence affects the turnover intention.

• 정보보호학회논문지
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• 제17권5호
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• pp.15-25
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• 2007

최근 프라이버시 보호에 대한 관심 및 요구가 증가함에 따라 다양한 응용환경에서 익명성을 제공하려는 연구가 진행되고 있다. 익명성을 제공하는 애드 혹 라우팅은 네트워크에 참여하는 노드에게 프라이버시를 보장해 줄 뿐 아니라 네트워크의 정보 수집을 제한하는 장점을 가진다. 현재까지 다수의 익명라우팅 기법들이 제안되었지만 대부분의 기법들은 인증을 고려하지 않고 있어서 패킷 변조뿐만 아니라 서비스 거부 공격에 매우 취약할 수 있다. 본 논문에서는 MANET 및 VANET 등과 같은 모바일 애드 혹 네트워크 환경에서 익명성과 인증을 동시에 제공하는 라우팅 프로토콜을 제안한다. 제안하는 기법은 애드 혹 네트워크에서 제공해야 할 익명성을 모두 지원하고 그룹서명 기법에 기반하여 경로 탐색 과정동안 노드와 메시지에 대한 인증을 제공한다. 그리고 경로 탐색 과정과 세견키 공유 절차가 통합되어 안전한 데이터 전송 과정을 지원한다.

• 정보보호학회논문지
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• 제19권2호
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• pp.93-103
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• 2009

본 논문에서는 3GPP 네트워크에서 USIM 기반의 사용자 인증 기법을 제안한다. 제안 기법은 기존의 3GPP 네트워크 접속을 위한 인증 방식에서 발생 가능한 Sequence Number 동기 문제, 인증 데이터 Overhead 문제, 네트워크 간 시그널링 Overhead 문제 등을 개선한다. 제안 기법은 기존의 USIM 기반의 AKA 인증 프로토콜을 기본 모델로 사용하고 단말과 SN이 공유한 SK와 Time Stamp를 통해서 AKA 인증 절차를 수행하도록 한다. 이렇게 함으로써 인증 벡터의 Sequence Number의 동기 여부를 확인할 필요 없이 Time Stamp 값으로 인증 벡터의 맵핑을 수행하여 Sequence Number 동기 문제를 해결할 수 있다. 뿐만 아니라 하나의 인증 벡터만을 관리하여 사용하기 때문에 SN에서의 인증 데이터 Overhead문제를 해결하고, SN과 HN 사이의 시그널링 Overhead 문제를 개선할 수 있다.

• 정보보호학회논문지
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• 제22권2호
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• pp.213-224
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• 2012

통합된 코어 망 구조(core network architecture)와 다양한 무선 가입자 행동들은 3GPP in Release 8에서 제안된 EPC(Evolved Packet Core Network)에서 상당한 시그널링 부하 증가를 가져온다. 따라서 인증 시그널링 분석(authentication signaling analysis)은 체감품질(quality-of-experience)을 충족시키면서 인증 시그널링 부하와 지연을 줄이는 통찰력을 갖게 해준다. 본 논문에서는 갱신 과정 이론(renewal process theory)에 기반을 둔 분석적 모델링을 통해 EPS 구조에서의 시그널링 부하에 대해 평가하였다. 갱신 과정 이론은 특정 랜덤 과정(random process)에 상관없이 잘 작동 한다 (예. 포아송(Poisson)). 본 논문은 발신 발생 속도(call arrival rate), 이동성(mobility), 가입자들의 선호도와 운영정책의 관점에서 가입자들의 다양한 패턴을 고려하였다. 매개변수들과 성능지표들 사이의 상호관계를 나타내기 위해 수치적인 결과를 사용하였다. 수직적 핸드오버(vertical handover) 성능의 민감도와 heavy-tail process의 영향에 대해서도 검토하였다.