• Journal of Animal Science and Technology
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• v.60 no.12
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• pp.32.1-32.10
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• 2018

Background: Necdin (NDN), a member of the melanoma antigen family showing imprinted pattern of expression, has been implicated as causing Prader-Willi symptoms, and known to participate in cellular growth, cellular migration and differentiation. The region where NDN is located has been associated to QTLs affecting reproduction and early growth in cattle, but location and functional analysis of the molecular mechanisms have not been established. Methods: Here we report the sequence variation of the entire coding sequence from 72 samples of cattle, yak, buffalo, goat and sheep, and discuss its variation in Bovidae. Median-joining network analysis was used to analyze the variation found in the species. Synonymous and non-synonymous substitution rates were determined for the analysis of all the polymorphic sites. Phylogenetic analysis were carried out among the species of Bovidae to reconstruct their relationships. Results: From the phylogenetic analysis with the consensus sequences of the studied Bovidae species, we found that only 11 of the 26 nucleotide changes that differentiate them produced amino acid changes. All the SNPs found in the cattle breeds were novel and showed similar percentages of nucleotides with non-synonymous substitutions at the N-terminal, MHD and C-terminal (12.3, 12.8 and 12.5%, respectively), and were much higher than the percentage of synonymous substitutions (2.5, 2.6 and 4.9%, respectively). Three mutations in cattle and one in sheep, detected in heterozygous individuals were predicted to be deleterious. Additionally, the analysis of the biochemical characteristics in the most common form of the proteins in each species show very little difference in molecular weight, pI, net charge, instability index, aliphatic index and GRAVY (Table 4) in the Bovidae species, except for sheep, which had a higher molecular weight, instability index and GRAVY. Conclusions: There is sufficient variation in this gene within and among the studied species, and because NDN carry key functions in the organism, it can have effects in economically important traits in the production of these species. NDN sequence is phylogenetically informative in this group, thus we propose this gene as a phylogenetic marker to study the evolution and conservation in Bovidae.

• Korean Journal of Heritage: History & Science
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• v.52 no.3
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• pp.94-111
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• 2019

This study aims to examine the evolutionary process of the protection-management system for historic monuments and their surroundings in France over one-hundred years. Because France and Korea shared policies and institutions regarding the management of historical monuments (cultural property) along with their surroundings, it is necessary to explore the French experience from a comparative perspective. In France, historical monuments began to be recognized as national heritage according to "the 1913 law" which has continued to evolve for more than one hundred years. In the beginning, a historical monument was preserved as a single building unit; however, since 1943, a new policy has been implemented to preserve sets of historical monuments along with their perimeters of protection zones. Moreover, since 1980, in the context of decentralization, local authorities have been given more roles and autonomy concerning the management of historic monuments and their surroundings. Local authorities have played a key role in the protection-management of historic monuments and their surroundings, and have become more active in the conservation of their architectural heritage, including historic monuments. The central government, however, remains as the headquarters whose rigorous policies provide a solid foundation for the decentralized management system of architectural and cultural heritage, including historic monuments. The final goal in the evolutionary process, then, targets the effective and harmonious integration of the protection-management system for historic monuments and their surroundings into urban and regional planning.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.12
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• pp.1646-1653
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• 2020

In case that the train driving with diverse high-speeds is manipulates by real-time remote control in long-term evolution-railway (LTE-R) system with frequent handovers, the real-time safe transmission of train control messages is important element. The handover delay time stability method regardless of train speed in order to enhance the real-time remote train control stability in LTE-R system is proposed in the paper. Furthermore, the variable speeds and altitudes of train collected by real measurements are applied for upgrading simulation accuracy. The simulation results inform that not only there are stable and unstable ranges to A3 offset values, but the optimal offset value for average handover delay is in unstable range. However, the late handover with A3 offset values in stable range should be chosen to get the predictable handover delay regardless of train speed rather than the early handover with A3 offset values in unstable range, since the key value of high-speed Korea railway system is the stability.

• Tunnel and Underground Space
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• v.32 no.6
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• pp.568-585
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• 2022

In the present study, we proposed a numerical method for simulating thermally induced fracture slip using a grain-based distinct element model (GBDEM). As a part of DECOVALEX-2023, the thermo-mechanical loading test on a saw-cut rock fracture conducted at the Korea Institute of Civil Engineering and Building Technology was simulated. In the numerical model, the rock sample including a saw-cut fracture was represented as a group of random Voronoi polyhedra. Then, the coupled thermo-mechanical behavior of grains and their interfaces was calculated using 3DEC. The key concerns focused on the temperature evolution, thermally induced principal stress increment, and fracture normal and shear displacements under thermo-mechanical loading. The comparisons between laboratory experimental results and the numerical results revealed that the numerical model reasonably captured the heat transfer and heat loss characteristics of the rock specimen, the horizontal stress increment due to constrained displacement, and the progressive shear failure of the fracture. However, the onset of the fracture slip and the magnitudes of stress increment and fracture displacement showed discrepancies between the numerical and experimental results. We expect the numerical model to be enhanced by continuing collaboration and interaction with other research teams of DECOVALEX-2023 Task G and validated in further study.

• Korean Journal of Mineralogy and Petrology
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• v.35 no.3
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• pp.199-214
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• 2022

The Yeongnam Massif is one of representative basement provinces in the Korean Peninsula, which has experienced high-temperature, low-pressure (HTLP) regional metamorphism and partial melting. Here we reviewed recent developments in Paleoproterozoic (1.87-1.84 Ga) hot orogenesis of the Yeongnam Massif, typified by the granulite-facies metamorphism and partial melting recorded in the HTLP rocks. In particular, spatiotemporal linkage between the metamorphic and magmatic activities, including the Sancheong-Hadong anorthositic magma as a heat source, provides a key to understand the widespread HTLP metamorphism and partial melting in the Yeongnam Massif. Crustal anatexis, resulting from the fluid-present melting and muscovite/biotite dehydration melting, has yielded various types of leucosomes and leucogranites. Zircon and monazite petrochronology, using in-situ U(-Th)-Pb data from the secondary ion mass spectrometry, indicates that the HTLP metamorphism and anatexis lasted over a period of ~15 Ma at ca. 1870-1854 Ma. In addition, a fluid influx event at ca. 1840 Ma was locally recognized by the occurrence of incipient charnockite. Taken together, the Yeongnam Massif preserves a prolonged evolutionary record of the HTLP metamorphism, partial melting, and fluid influx diagnostic for a hot orogen. Such an orogen is linked to the Paleoproterozoic orogeny widespread in the North China Craton, and most likely represents the final phase of crustal evolution in the Columbia/Nuna supercontinent.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.33 no.2
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• pp.93-102
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• 2023

Objectives: With the evolution of direct reading sensors, it is possible to monitor several substances through telecommunication. However, there are some limitations on the use of direct reading technologies in the Occupational Safety and Health Act in South Korea, which only applies to detector tubes, noise, heat, and carbon monoxides. The number of chemicals and their amount of use have been continuously increasing in South Korea. The Ministry of Employment and Labor (MoEL) has concerns about worker's health because exposure is only covered for about 1.2% of all distributed chemicals. Using a direct reading monitor with photoionization detectors (PID-DRMs), gases and vapors chemicals can be measured. Based on the data, business owners are able to create corrective strategies, provide better working routines, and select correct respiratory equipment. PID-DRMs are less expensive and easier to handle for an owner voluntarily controlling chemicals emitted in the workplace. However, there are several limitations on using these PID-DRMs to the degree that the MoEL has not been able to select a legal monitor. The aim of this study was to review previous studies related to PID-DRMs and identify the characterization and limitation on PID-DRMs. Methods: To search for related studies on PID-DRMs, key words were used including direct reading monitors/instruments and/or photoionization detectors. Through that, four domestic and 15 international studies were reviewed. Results: Studies on PID-DRMs were conducted by chamber (enclosed, dynamic, walk-in) and in the field (experimental environment, actual environment). The concentration of PID-DRMs and charcoal tubes were compared for a single substance or mixture, or within the PID-DRMs. There was a high correlation between the two concentrations, but it did not meet the accuracy criteria (95% confidence interval, within 25%) of the NIOSH technical report (2012). In addition, differences in measured values occurred according to environmental factors (temperature, humidity) and high concentration, and concentration values tended to be underestimated due to contamination of the sensor. As a way to improve the accuracy of PID concentration, it was proposed to use correction factors, charcoal tube-based correction factors, or to calibrate the PID-DRMs in the same environment as the workplace. Conclusions: PID-DRMs can likely be used by business owners for the purpose of voluntarily managing the workplace environment, and it is expected that it will be possible to use them as legal equipment if a PID sensor can be upgraded and the limitations of the sensor (temperature, humidity, high concentration evaluation, sensor pollution) can be overcome in the near future.

• Journal of The Korean Association For Science Education
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• v.36 no.4
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• pp.591-606
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• 2016

The purpose of this study is to develop the argumentation program to build scientific concepts on natural selection for science-gifted elementary students and to know how to implement this program. For this study, nine key concepts about natural selection such as the overproduction of offspring, limited resources, population stability, competition, variation, heredity of variation, differential survival, change of the population and speciation were selected through the literature study. The programs were developed by learning cycle instructional model. Argument writings and discourses have been collected, analyzed and compared before and after the program. Two questionnaires to compare pre and post concept change consist of multiple choice questionnaire and open-ended response question were developed and applied to 19 science-gifted elementary students. Sufficiency of the explanation and conceptual quality of the explanation were used to assess the quality of their arguments before and after the program. Discourse and visual models collected from the highest and lowest group about score improvement were compared. The scores of the gifted statistically improved significantly in multiple choice questionnaire. Students' alternative conceptions about natural selection at the beginning of the program decreased and changed scientifically after the program. Visual models drawn by the students supported the results as well. This study asserts that elementary science-gifted students are able to explain evolutionary perspectives about organism change and use the key concepts of natural selection. The study means that evolutionary perspective is possible to be reflected in elementary science curriculum for the gifted.

• Maritime Security
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• v.4 no.1
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• pp.1-56
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• 2022

Why has India become a key actor in the maritime-configured Indo-Pacific region? There are some external factors, but for India, its geo-strategic frontier encompassing its geopolitical and maritime interests is expanding rapidly beyond its territorial space across both the Indian and Pacific oceans amidst an increasingly arduous geopolitical and security environment. India must, therefore, acquire the ability to influence events within this strategic arena using all facets of national power, including maritime-military power. Lately, therefore, New Delhi has invested much intellectual capital to review its maritime-security strategy. India's new strategy is premised on the concept of holistic security involving the 'softer' aspects of maritime-security, and a rekindling of maritime consciousness in India, a nation that has traditionally been beset by 'sea-blindness'. The strategy adopts a region-wide, inclusive, and a more proactive approach than hitherto, as is evident in its title 'Ensuring Secure Seas: Indian Maritime Security Strategy'. While it deals with the growing concern of new non-traditional threats in the Indian littoral and the need for military deterrence and preparedness, it also addresses the imperatives for India to seek a favorable and rules-based benign environment in its immediate and extended maritime periphery, including through multi-vectored strategic partnerships dictated by its enduring principle of strategic autonomy. For a more profound and comprehensive understanding of India's maritime-security strategy, this paper examines the key unstated and implicit factors that underpin the strategy. These include India's historical and cultural evolution as a nation; its strategic geography; its geopolitical and security perceptions; and the political directions to its security forces. The paper deals specifically with India's response to maritime threats ranging from natural disasters, crime and state-sponsored terrorism to those posed by Pakistan and China, as well as the Indian Navy's envisaged security role East of the Malacca Straits. It also analyzes the aspects of organizational restructuring and force planning of India's maritime-security forces.

• Journal of Global Scholars of Marketing Science
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• v.20 no.1
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• pp.35-48
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• 2010

Today, the fashion market challenged by a maturing retail market needs a new paradigm in the "evolution of brand" to improve their comparative advantages. An important issue in fashion marketing is lifestyle brand extension with a specific aim to meet consumers' specific needs for their changing lifestyle. For fashion brand extensions into lifestyle product categories, Gen Y and Baby Boomer are emerging as "prospects"-Baby Boomers who are renovating their lifestyle, and generation Y experiencing changes in their life stage-with demands for buying new products. Therefore, it is imperative that apparel companies pay special attention to the consumer cohort for brand extension to create and manage their brand equity in a new product category. The purposes of this study are to (a) evaluate brand equity between parent and extension brands; (b) identify consumers' perceived marketing elements for brand extension; and (c) estimate a structural equation model for examining causative relationship between marketing elements and brand equity for brand extensions in lifestyle product category including home fashion items for the selected two groups (e.g., Gen Y, and Baby boomer). For theoretical frameworks, this study focused on the traditional marketing 4P's mix to identify what marketing element is more importantly related to brand extension equity for this study. It is assumed that comparable marketing capability can be critical to establish "brand extension equity", leads to successfully entering the new categories. Drawing from the relevant literature, this study developed research hypotheses incorporating brand equity factors and marketing elements by focusing on the selected consumers (e.g., Gen Y, Baby Boomer). In the context of brand extension in the lifestyle products, constructs of brand equity consist of brand awareness/association, brand perceptions (e.g., perceived quality, emotional value) and brand resonance adapted from CBBE factors (Keller, 2001). It is postulated that the marketing elements create brand extension equity in terms of brand awareness/association, brand perceptions by the brand extension into lifestyle products, which in turn influence brand resonance. For data collection, the sample was comprised of Korean female consumers in Gen Y and Baby Boomer consumer categories who have a high demand for lifestyle products due to changing their lifecycles. A total of 651 usable questionnaires were obtained from female consumers of Gen Y (n=326) and Baby Boomer (n=325) in South Korea. Structural and measurement models using a correlation matrix was estimated using LISREL 8.8. Findings indicated that perceived marketing elements for brand extension consisted of three factors: price/store image, product, and advertising. In the model of Gen Y consumers, price/store image had a positive effect on brand equity factors (e.g., brand awareness/association, perceived quality), while product had positive effect on emotional value in the brand extensions; and the brand awareness/association was likely to increase the perceived quality and emotional value, leading to brand resonance for brand extensions in the lifestyle products. In the model of Baby Boomer consumers, price/store image had a positive effect on perceived quality, which created brand resonance of brand extension; and product had a positive effect on perceived quality and emotional value, which leads to brand resonance for brand extension in the lifestyle products. However, advertising was negatively related to brand equity for both groups. This study provides an insight for fashion marketers in developing a successful brand extension strategy, leading to a sustainable competitive advantage. This study complements and extends prior works in the brand extension through critical factors of marketing efforts that affect brand extension success. Findings support a synergy effect on leveraging of fashion brand extensions (Aaker and Keller, 1990; Tauber, 1988; Shine et al., 2007; Pitta and Katsanis, 1995) in conjunction with marketing actions for entering into the new product category. Thus, it is recommended that marketers targeting both Gen Y and Baby Boomer can reduce marketing cost for entering the new product category (e.g., home furnishings) by standardized marketing efforts; fashion marketers can (a) offer extension lines with premium ranges of price; (b) place an emphasis on upscale features of store image positioning by a retail channel (e.g., specialty department store) in Korea, and (c) combine apparel with lifestyle product assortments including innovative style and designer’s limited editions. With respect to brand equity, a key to successful brand extension is consumers’ brand awareness or association that ensures brand identity with new product category. It is imperative for marketers to have knowledge of what contributes to more concrete associations in a market entry into new product categories. For fashion brands, a second key of brand extension can be a "luxury" lifestyle approach into new product categories, in that higher price or store image had impact on perceived quality that established brand resonance. More importantly, this study increases the theoretical understanding of brand extension and suggests directions for marketers as they establish marketing program at Gen Y and Baby Boomers.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.6 no.4
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• pp.265-273
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• 2001

The sea urchin has been used as sea food in many countries. This species has also been an important organism of embryological studies for more than a century. In recent years, sea urchin embryos are being used as testing materials for toxicity of pollutants and toxins. Usefulness of sea urchin embryos as experimental models comes from the easiness in obtaining sea urchin samples and a lot of gametes, in rearing embryos in the laboratory, in observing the cellular movement and organ formation during the embryogenesis and in manipulating blastomeres and genetic maferials. The sea urchin in itself is a key organism for the understanding of deuterostome evolution from the protostomes and of indirect development of marine invertebrates which undergo the planktotrophic larval stage. A fertilized sea urchin egg goes through rapid cleavage and becomes a 60 cell embryo 7hr after fertilization. It then develops into a morula, a blastula, a gastrula and finally a pluteus larva approximately 70 hr after fertilization. At the 60 cell stage, the embryo comprises of five territories that express territory-speciflc genes and later form different organs. Micromeres at the vegetal pole ingress into the blastoceol and become the primary mesenchyme cells(PMCs). PMCs express genes involved in skeletogenesis such as SM30, SM37, SM50, PM27, msp130. Among the genes, SM37 and SM50 are considered to be members of a gene family which is characterized by early blastula expression, Glycine-Proline-Glutamine rich repeat structures and spicule matrix forming basic proteins. Genetic studies on the sea urchin embryos help understand the molecular basis of indirect development of marine invertebrates and also of the biomineralization common to the animal kingdom.