• Title/Summary/Keyword: Ketones.

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Preparation and Catalytic Application of Pd Loaded Titanate Nanotube: Highly Selective α Alkylation of Ketones with Alcohols

  • Jang, Jum-Suk;Kwon, Min-Serk;Kim, Hyun-Gyu;Park, Jae-Wook;Lee, Jae-Sung
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1617-1621
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    • 2012
  • The titanate nanotube (TNT) was hydrothermally synthesized in 10 M NaOH aqueous solution at $150^{\circ}C$ for 72 h. Titanate nanotube with high surface area (292 $m^2$/g) is a good candidate as a support for catalytic reaction or organic synthesis. Palladium nanoparticles with an average size of $ca$. 3 nm were well dispersed onto the surface of TNT nanotubes. Palladium loaded catalyst with high surface area shows a highly efficient ${\alpha}$ alkylation of ketones with primary alcohols.

(Pyridine)(tetrahydroborato)zinc Complex, [Zn(BH4)2(py)], as a New Stable, Efficient and Chemoselective Reducing Agent for Reduction of Carbonyl Compounds

  • Zeynizadeh, Behzad;Faraji, Fariba
    • Bulletin of the Korean Chemical Society
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    • v.24 no.4
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    • pp.453-459
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    • 2003
  • (Pyridine)(tetrahydroborato)zinc complex, $[Zn(BH_4)_2(py)]$, as a stable white solid, was prepared quantitatively by complexation of an equimolar amount of zinc tetrahydroborate and pyridine at room temperature. This reagent can easily reduce variety of carbonyl compounds such as aldehydes, ketones, acyloins, α-diketones and a, β-unsaturated carbonyl compounds to their corresponding alcohols in good to excellent yields. Reduction reactions were performed in ether or THF at room temperature or under reflux conditions. In addition, the chemoselective reduction of aldehydes over ketones was accomplished successfully with this reducing agent.

Asymmetric Michael Reaction of Malonate Derivatives with α, β-Unsaturated Ketones

  • Cho, Min-Je;Cho, Myoung-Gi;Huh, Sun-Chul;Kim, Sung-Min;Lee, Kil-sung;Koh, Kwang-Oh;Mang, Joo-Yang;Kim, Dae-Young
    • Bulletin of the Korean Chemical Society
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    • v.27 no.6
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    • pp.857-862
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    • 2006
  • The catalytic enantioselective Michael reaction promoted by quaternary ammonium salts from Cinchona alkaloids as a phase-transfer catalyst is described. Treatment of malonates with $\alpha$,$\beta$-unsaturated ketones under mild reaction conditions afforded the corresponding Michael adducts in good yields with good to moderate enantiomeric excesses.

Highly Selective Synthesis of β-Amino Carbonyl Compounds over ZSM-5-SO3H under Solvent-free Conditions

  • Massah, Ahmad Reza;Kalbasi, Roozbeh Javad;Samah, Neda
    • Bulletin of the Korean Chemical Society
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    • v.32 no.5
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    • pp.1703-1708
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    • 2011
  • ZSM-5-$SO_3H$ efficiently catalyzed the one-pot three-component Mannich reaction of aldehydes, anilines, and ketones. ${\beta}$-Aminocarbonyl compounds were obtained in reasonable yields and excellent stereoselectivities when the reaction was carried out at room temperature under solvent-free conditions. Simple experimental conditions and product isolation procedure makes this protocol potential for the development of clean and environment-friendly strategy for the synthesis of ${\beta}$-amino-ketones. The catalyst was recovered and reused for subsequent runs.