• Title/Summary/Keyword: KT

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PKA Inhibitor KT5720, Suppressed Cytoskeletal Components Effect by Vesicular Stomatitis Virus, but did not Affect the Viral Replication

  • Kim, Young-Sook
    • KSBB Journal
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    • v.22 no.5
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    • pp.282-287
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    • 2007
  • The antiviral mechanism of KT5720 is known to inhibit the cAMP-dependent protein kinase (PKA), on the VSV infection in BHK-21 cell cultures. The virus inducted CPE (cell rounding) was almost completely suppressed by KT5720 at 5 uM. The inhibitor, however, did not affect the replication of the virus and the synthesis of viral macromolecules. Immunological studies showed the viral matrix (M) protein displayed intimate association with the cytoskeletal components and probably the cell rounding. KT5720, did not block the cytoskeletal disruption, while the cell rounding was suppressed. These observations suggest that the interaction between the viral M protein and the cytoskeletal components may not be enough to cause the morphological change of the cell. And, the KT5720-sensitive function may be involved in developing the VSV-induced CPE, but not essential for the virus replications.

HomeN manager system based on multimodal context-aware middleware (멀티모달 상황인지 미들웨어 기반의 홈앤(HomeN) 매니저 시스템)

  • Ahn, Se-Yeol;Park, Sung-Chan;Park, Seong-Soo;Koo, Myung-Wan;Jeong, Yeong-Joon;Kim, Myung-Sook
    • Proceedings of the KSPS conference
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    • 2006.11a
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    • pp.120-123
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    • 2006
  • The provision of personalized user interfaces for mobile devices is expected to be used for different devices with a wide variety of capabilities and interaction modalities. In this paper, we implemented a multimodal context-aware middleware incorporating XML-based languages such as XHTML, VoiceXML. SCXML uses parallel states to invoke both XHTML and VoiceXML contents as well as to gather composite multimodal inputs or synchronize inter-modalities through man-machine I/Os. We developed home networking service named "HomeN" based on our middleware framework. It demonstrates that users could maintain multimodal scenarios in a clear, concise and consistent manner under various user's interactions.

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A Study on the Store Compliance Verification for KT-1P Aircraft

  • Kim, Dae-wook;Kim, Chan-jo;Wu, Bong-gil
    • International Journal of Aerospace System Engineering
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    • v.2 no.2
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    • pp.87-91
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    • 2015
  • KT-1P for the Peru Air Force will be used as a utility aircraft with upgraded avionics equipment and arming capability based on KT-1 and KA-1. KT-1P should be shown for compatibility of new store loading configurations loaded with dispenser, bomb, and rocket based on aircraft-store compatibility test and evaluation procedures before KT-1P is operated as a light attack aircraft. The weapon system ground test for installation and flight test for envelope expansion including store separation are described in this paper, which was performed referring 'seek eagle program' under MIL-HDBK-1763 and MIL-HDBK-244A.

Immediate Effect of Kinesiology Taping on Gait Function in Stroke Patients with Foot Drop

  • Kim, Jinuk
    • Journal of International Academy of Physical Therapy Research
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    • v.11 no.2
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    • pp.2060-2064
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    • 2020
  • Background: Recently, the kinesiology taping (KT) method was reported to be effective in improving walking ability in foot drop patients after stroke, but the clinical basis is still unclear. Objectives: The KT method was compared with ankle-foot orthotics (AFO) to investigate gait ability in foot drop patients after stroke. Design: Crossover study design. Methods: In this study, 11 stroke patients with foot drop participated. Walking ability of all subjects for both conditions (KT and AFO) was measured using the GAITRite system. The order of application of the two conditions was determined randomly by drawing lots. Wilcoxon signed-rank test was used to compare walking ability between the two conditions. The level of statistical significance was set at P<.05. Results: There were no significant differences between the KT and AFO methods in terms of velocity, cadence, step length, and stride length (P>.05, all). Conclusion: This study recommends KT as an alternative to the AFO, since KT provides evidence of preventing of foot drops and improving gait ability in stroke patient.

Factual consistency checker through a question-answer test based on the named entity (개체명 기반 질문-답변 검사를 통한 요약문 사실관계 확인)

  • Jung, Jeesu;Ryu, Hwijung;Chang, Dusung;Chung, Riwoo;Jung, Sangkeun
    • Annual Conference on Human and Language Technology
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    • 2021.10a
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    • pp.112-117
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    • 2021
  • 기계 학습을 활용하여 요약문을 생성했을 경우, 해당 요약문의 정확도를 측정할 수 있는 도구는 필수적이다. 원문에 대한 요약문의 사실관계 일관성의 파악을 위해 개체명 유사도, 기계 독해를 이용한 질문-답변 생성을 활용한 방법이 시도되었으나, 충분한 데이터 확보가 필요하거나 정확도가 부족하였다. 본 논문은 딥러닝 모델을 기반한 개체명 인식기와 질문-답변쌍 정확도 측정기를 활용하여 생성, 필터링한 질문-답변 쌍에 대해 일치도를 점수화하는 방법을 제안하였다. 이러한 기계적 사실관계 확인 점수와 사람의 평가 점수의 분포를 비교하여 방법의 타당성을 입증하였다.

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Pretraining Dense retrieval for Multi-hop question answering of Korean (한국어 다중추론 질의응답을 위한 Dense Retrieval 사전학습)

  • Kang, Dong-Chan;Na, Seung-Hoon;Kim, Tae-Hyeong;Choi, Yun-Su;Chang, Du-Seong
    • Annual Conference on Human and Language Technology
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    • 2021.10a
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    • pp.588-591
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    • 2021
  • 다중추론 질의응답 태스크는 하나의 문서만 필요한 기존의 단일추론 질의응답(Single-hop QA)을 넘어서 복잡한 추론을 요구하는 질문에 응답하는 것이 목표이다. IRQA에서는 검색 모델의 역할이 중요한 반면, 주목받고 있는 Dense Retrieval 모델 기반의 다중추론 질의응답 검색 모델은 찾기 어렵다. 본 논문에서는 검색분야에서 좋은 성능 보이고 있는 Dense Retrieval 모델의 다중추론을 위한 사전학습 방법을 제안하고 관련 한국어 데이터 셋에서 이전 방법과의 성능을 비교 측정하여 학습 방법의 유효성을 검증하고 있다. 이를 통해 지식 베이스, 엔터티 링킹, 개체명 인식모듈을 비롯한 다른 서브모듈을 사용하지 않고도 다중추론 Dense Retrieval 모델을 학습시킬 수 있음을 보였다.

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