• Journal of Advanced Research in Ocean Engineering
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• v.4 no.2
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• pp.78-85
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• 2018

This paper presents a study of the effects of the free surface to marine propeller including the mesh effect of the models. In the present study, we conduct the numerical simulation for propeller performance employing the openwater test. The numerical simulations compare the meshing strategies for the propeller and show the effects on both thrust and torque. OpenFOAM is applied to solve the propeller problem and then open water performances of KCS propeller (KP505) are estimated using a Reynold-averaged Navier-Stokes equations (RANS) solver and the turbulence of the $K-{\omega}$ SST model. Unstructured meshes are used in the numerical simulation employing hexahedral meshing for mesh generation. The arbitrary mesh interfacing (AMI) and multiple rotating frame (MRF) are compared to define the best meshing strategy. The meshing strategies are evaluated through 3 classifications, i.e., coarse, medium, and fine mesh. Thus, the propeller can be performed utilizing the best mesh strategy. The computational results are validated by comparison with the experimental results. The $K_T$, $K_Q$, and efficiency of the propeller are compared to an experimental result and for all of the meshing strategies. Thus, the simulations show the influence of meshing in order to perform the propeller performances.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.5
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• pp.757-766
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• 2002

Growth hormone-releasing peptide-2 (GHRP-2, also named KP102) is a new hexapeptide of a series of synthetic growth hormone-releasing peptides (GHRPs) which stimulates the secretion of growth hormone (GH) in vitro and in vivo in several species including calf, sheep and pig. The GH-releasing activity of GHRP-2 is two to three times more effective than that of the original GHRP-6, and GHRP-1 in the rats and humans. To date, GHRP-2 seems to be the most potent member of the family of GHRPs. Since the GHRPs are short peptides (5-7 amino acid residues), they are synthesized easily and are not as readily degraded in plasma as GHreleasing hormone (GHRH). These features ameliorate their potential on domestic animals because of their chemical nature the GHRPs are efficacious when administered i.v. orally or orally. However, studies in cow, pig and sheep do not indicate such a close relationship between GHRH, somatostatin (SS) and GH, calling into question the general applicability of the human and rat models. Perhaps there is an important role for an endogenous GHRP in the regulation of GH secretion in domestic animals. This review provides an overview on the current knowledge of physiological role of GHRP-2 in domestic animals.

• YAKHAK HOEJI
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• v.48 no.5
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• pp.297-302
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• 2004

The purpose of the present study was to evaluate the bioequivalence of two cimetidine tablets, Tagamet (Yuhan Pharm. Co., Ltd.) and Nex (Bi-nex Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The cimetidine release from the two cimetidine tablets in vitro was tested using KP Apparatus I method with various dissolution media (pH 1.2, 4.0, 6.8 buffer solutions and water). The dissolution profiles of two cimetidine tablets were very similar at all dissolution media. Twenty four healthy male volunteers were divided into two groups with a randomized $2{\times}2$ cross-over study. After four tablets (800 mg cimetidine) were orally administrated, blood was taken and the concentrations of cimetidine in serum were determined using HPLC with UV detector. The pharmacokinetic parameters such as $AUC_{t}$, $C_{max}$ and $T_{max}$ were determined. The result showed that the differences in $AUC_{t}$, and $C_{max}$ between two cimetidine tablets based on the Tagamet were -6.82% and -12.98%, respectively. There were no sequence effects between two tablets in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.90)log(0.97) and log(0.82)log(0.93) for $AUC_{t}$ and $C_{max}$, respectively), indicating that Thrumetin tablet was bioequivalent to Tagamet tablet.

• Korean Journal of Breeding Science
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• v.41 no.1
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• pp.1-8
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• 2009

This study was carried out to breed and develop high quality and functional nutrient tomato with multi disease resistance as well as a stable growing adaptation for fresh market usage under protected plastic houses cultivation. The materials were used 5 inbred lines and their 6 hybrids of large tomato group, which have been bred and developed from 1999 to 2007 in Division of Plant Resource Department of Chungnam National University. Fruit weight showed hybrid vigor effect that $F_1$ hybrids weighed more than their parent lines, fruit shape formed three type of oblate, deep oblate and globe shape, in firmness and pericarp thickness have got a high significant correlation, inbred DN611 line was measured the most firm fruit with 6.04 mm pericarp thickness. In fruit color at maturity, pink color crossed to red color appeared all red fruit color in the $F_1$ hybrids, it means red skin color is a dominant gene compared to pink skin color is a recessive gene in tomato, while between fruit skin color and shoulder part color showed no any co-relationship. The sugar content and titratable acid of $F_1$ hybrids inherited an intermediate data of their parent lines, the flavor of KP543 inbred line and the hybrid (JB535 x KP543) revealed the better taste with high brix and proper titratable acid content$^{*}$. In beta carotene content DN611 line showed 2~3 times higher than other materials so that its 3 hybrids contained an increased level of beta carotene, lycopene content was not so much difference among inbred lines and $F_1$ hybrids, of them MD508 contained higher of 8.72 mg and hybrid (JB535 x JA517) had 8.05 mg lycopene content per 100 g fruit, overall pink skin color and red skin color measured a higher lycopene content than yellow and orange skin color at ripe stage. In disease resistance test by PCR marker for Fusarium race2 (I2), Nematode (Mi1), ToMV ($Tm2^2$), Cladosporium (Cf9), (JB535 x JA517) hybrid have got multi-resistance with homozygote band in Nematode, ToMV, Cladosporium and heterozygote band in Fusarium race2. Through this breeding program we could select high quality and functional nutrient with multi resistant $F_1$ hybrids and inbred lines in tomato which are two best hybrids (JB535 x MD508), (JB535 x JA517), additionally developed high beta carotene inbred line DN611 and increased the level of lycopene inbred line MD508. These results will be very useful to make a high quality tomato variety continuously.

• Journal of Environmental Science International
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• v.18 no.12
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• pp.1361-1368
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• 2009

The effects of $Cd^{2+}$ ions on the Chl a fluorescence of 5 hydrophytes (e.g. Lemna, Salvinia, Ricciocarp, Nymph, Typha plants) were investigated in order to select $Cd^{2+}$-sensitive plant species and to get informations on physiological responses of plants to $Cd^{2+}$ stress. Lemna plants were most sensitive to cadmium stress, while Nymph plants were tolerant. However, in all $Cd^{2+}$-treated plants, Fv/Fm, the maximum photochemical efficiency of PS II, decreased in proportion to the increase of $Cd^{2+}$ concentration and treatment time. The Chl a fluorescence transient O-J-I-P was also considerably affected by $Cd^{2+}$ ions; the fluorescence yield decreased consid- erably in steps J, I and P in $Cd^{2+}$ treated plants, although it followed a typical polyphasic rise in non-treated plants. In Lemna plants, the functional parameters, ABS/CS, TRo/CS와 ETo/CS and RC/CS, decreased in proportion to the increase of $Cd^{2+}$ concentration, while N, Mo and Kn increased. The structural parameters, ${\Phi}po$, ${\Phi}po$/($1-{\Phi}po$), Plabs, SFlabs, Kp and RC/ABS, also decreased according to the increase of $Cd^{2+}$ concentration. Consequently, Lemna plants will be useful as a experimental model system to investigate responses of plants. And several functional or structural parameters could be applied to determine quantitatively the physiological states of plants under stresses.

• Journal of Pharmaceutical Investigation
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• v.36 no.3
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• pp.161-167
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• 2006

The objective of this study was to investigate the dissolution patterns of variety of orally administered drug products available on the market. It aimed to understand their dissolution behaviors on the basis of the biopharmaceutics classification system (BCS) concept. On the tenets of BCS, several active pharmaceutical ingredients were selected: fluoxetine hydrochloride (class I), naproxen sodium (class ll), pyridostigmine bromide (class III), furosemide (class IV) and simvastatin (class IV). Typical dissolution media used in this study were pH 1.2, pH 4 & 6.8 phosphate buffers, and water. In cases, particular dissolution media specified in the KP and/or USP were used. Dissolution patterns of fluoxetine hydrochloride and pyridostigmine bromide products were characterized by their rapid release In addition, their dissolution characteristics were relatively unaffected by the type of a dissolution medium. Similar dissolution patterns were observed with pH 1.2, pH 4 & 6.8 phosphate buffers and water. By sharp contrast, poor dissolution patterns were noticed with naproxen sodium products, when pH 1.2 and pH 4 phosphate buffer were used. Improvements in its dissolution were achieved by switching the dissolution media to pH 6.8 phosphate buffer or water. Unsatisfactory dissolution data also were observed with a simvastatin product, when it was subject to dissolution tests by use of a surfactant-free pH 1.2, pH 4 & 6.8 phosphate buffers and water. All the release patterns reported in this study were best understood when BCS concepts were implemented. Our results demonstrated that a BCS-based drug classification should be considered first to choose a dissolution test/method and set up dissolution specification.

• Journal of the Society of Naval Architects of Korea
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• v.36 no.3
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• pp.41-49
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• 1999

A feasibility study is performed for practical application of a Ventilating Water-Jet(VWJ) propulsor which attracts new attention as a candidate propulsor for super-high speed vessels. Super-cavitating foil sections are adopted for the rotor blades since the rotor is operating at ventilating condition. Wedge type and cavitator type foil sections are used for the design of rotor blades. Other geometric characteristics of rotors are selected from the Kaplan type ducted propeller rotors. The test section of KRISO cavitation tunnel is modified to perform open-water tests of the VWJ propulsors. The tests are performed both at fully-submerged and free-jet conditions. Ventilation occurred at the free-jet condition by sucking the air in the downstream side of the rotor, which easily develops as super-cavitation when the rotor operates at lower advance coefficients. Spoilers are attached at the trailing end of the pressure side of the blade section, in order to increase the lift force.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1244-1245
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• 2008

Recently, piezoelectric transformer is applied to wide fields. Multi layer piezoelectric transformer has the advantage of high step up ratio, electromechanical coupling coefficient(Kp) and mechanical quality factor(Qm), but is indicated of peeling-phenomenon of electrode, rising sintering temperature made price of costly electrode. So in this study, it discuss on method for fabrication of rosen type piezoelectric transformers. For the fabrication as rosen type piezoelectric transformers, synthesized the powder using 0.01Pb$(ni_{1/3}Nb_{2/3})O_3$ - 0.08Pb$(Mn_{1/3}Nb_{2/3})O_3$ - 0.91Pb$(Zr_{0506}Ti_{0496})O_3$ (abbreviated as PNN-PMN-PZT) ceramics. The density, microstructure, dielectric and piezoelectric properties as a function of sintering temperature were investigated. The results indicated that the optimized properties of ceramics were obtained at sintering temperature of 1200$^{\circ}C$, showed the value of $d_{33}$=273pC/N, $K_p$=0.60 $Q_m$=1585, ${\varepsilon}_r$=1454, density=7.917$g/cm^3$ and $tan{\delta}$=0.0064.

• Journal of Information Processing Systems
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• v.8 no.3
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• pp.495-520
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• 2012

A secure Electronic Payment System (EPS) is essential for the booming online shopping market. A successful EPS supports the transfer of electronic money and sensitive information with security, accuracy, and integrity between the seller and buyer over the Internet. SET, CyberCash, Paypal, and iKP are the most popular Credit Card-Based EPSs (CCBEPSs). Some CCBEPSs only use SSL to provide a secure communication channel. Hence, they only prevent "Man in the Middle" fraud but do not protect the sensitive cardholder information such as the credit card number from being passed onto the merchant, who may be unscrupulous. Other CCBEPSs use complex mechanisms such as cryptography, certificate authorities, etc. to fulfill the security schemes. However, factors such as ease of use for the cardholder and the implementation costs for each party are frequently overlooked. In this paper, we propose a Web service based new payment system, based on ANSI X9.59-2006 with extra features added on top of this standard. X9.59 is an Account Based Digital Signature (ABDS) and consumer-oriented payment system. It utilizes the existing financial network and financial messages to complete the payment process. However, there are a number of limitations in this standard. This research provides a solution to solve the limitations of X9.59 by adding a merchant authentication feature during the payment cycle without any addenda records to be added in the existing financial messages. We have conducted performance testing on the proposed system via a comparison with SET and X9.59 using simulation to analyze their levels of performance and security.

• Cross-Cultural Studies
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• v.41
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• pp.245-273
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• 2015

The purpose of this paper is to investigate the characteristics of some forms, "거" [kə], "게" [ke], and "걸" [kəl], which originated from a dependent noun "것" [kət]. Nowadays, some studies have argued that these forms are allomorphs of "것" [kət]. However, they are not allomorphs because they do not show a complementary distribution with "것" [kət]. Moreover, we should not deal with "게" [ke] and "걸" [kəl] as at the same level of "것" [kət] and "거" [kə] because they respectively consist of "거" [kə], and the subjective case marker "이" [i] or the accusative case marker "ㄹ" [l]. In other words, they function as an element of a sentence. Therefore, just the "거" [kə] and "걸" [kəl] remain to be argued about concerning variation among them. Especially, the "거" [kə] is almost freely alternated with "것" [kət], whereas even though "걸" [kəl], which is not part of KP (N + case marker), is very restricted so as to appear to be from "거" [kə]. Of course, the restriction they show cannot be under the condition that corresponds to the conception of the alternation. In conclusion, only the "거" [kə] is just an optional variation morph of "것" [kət], whereas "걸" [kəl] is an optional variation morph of "거" [kə]. There is no allomorph of "것" [kət] in the forms originated from itself.