• 제목/요약/키워드: KINETIC

검색결과 5,091건 처리시간 0.037초

Validation of Kinetic Method for the PKA Assay in Plasma-Derived Products

  • Shin, In-Soo;Hong, Choong-Man;Koh, Hyun-Chul;Hong, Seung-Hwa
    • Biomolecules & Therapeutics
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    • 제13권1호
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    • pp.59-63
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    • 2005
  • A kinetic assay was carried out in order to compare the ability of detection for prekallikrein activator(PKA) in plasma-derived products with that of an endpoint assay and a commercial method. Using these methods, 9 human albumin preparations were assayed and compared to each other. The coefficient of variation between the Kinetic assay and the end point assay was found within 6.6% and this result showed that two methods were highly correlative and the end point assay could act as a replacement of the kinetic assay. Another important goal of this study was to investigate the reproducibility among laboratories on the kinetic assay. A collaborative study was performed to validate the kinetic method with intra and inter assays. The coefficient of variation for the intra assay of each laboratory was less than 4% and that for between individuals in the inter assay was 4.1%. These results revealed that the kinetic assay showed good reproducibility. The contents of PKA in plasma-derived products were also determined by the kinetic assay. As a result, it was found that trace amounts of PKA were present in 32 human immunoglobulin preparations, however the average concentration of PKA in 171 albumin preparations was 5.8 IU/mL.

강우 운동에너지식에 따른 한국의 강우침식인자 평가 (Evaluation of Rainfall Erosivity in Korea using Different Kinetic Energy Equations)

  • 이준학;신주영;허준행
    • 한국토양비료학회지
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    • 제44권3호
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    • pp.337-343
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    • 2011
  • A particular empirical equation for rainfall kinetic energy is needed to compute rainfall erosivity, calculated by the annual sum of the product of total rainfall energy and maximum 30-min rainfall intensity. If rainfall kinetic energy equation was different, rainfall erosivity will be produced differently. However, the previous studies in Korea had little concern about rainfall kinetic energy equation and it was not clear which rainfall kinetic energy is suitable for Korea. The purpose of this study is to analyze and evaluate the difference of the rainfall erosivity based on different rainfall kinetic energy equations obtained from previous studies. This study introduced new rainfall erosivity factors based on rainfall kinetic energy equation of Noe and Kwon (1984) that is only regression model developed in Korea. Data of annual rainfall erosivity for 21 weather stations in 1980~1999 were used in this study. The result showed that rainfall erosivity factors by the previous equations had been about 10~20% overestimated than rainfall erosivity by Noe and Kwon (1984)'s equation in Korea.

정속가열(定速加熱)조건에서 표준온도상당시간(相當時間)을 이용한 비효소적 갈색화 반응의 동력학 파라미터 추정(推定) (Estimation of Kinetic Parameters of Nonenzymatic Browning Reaction Using Equivalent Time at Reference Temperarture with Linearly Increasing Temperature Profile)

  • 조형용;권윤중;김인규;변유량
    • 한국식품과학회지
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    • 제25권2호
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    • pp.178-184
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    • 1993
  • 식품의 품질변화에 미치는 온도의 영향을 분석하기 위한 kinetic parameters를 추정하는데 있어서 표준온도 상당시간이 유효함을 밝히기 위하여 비효소적 갈색반응 액체 모델 및 식품시스템을 직선적으로 온도를 증가시키는 조건$(6^{\circ}\;/h)$에서 반응시켰다. 표준온도 상당시간은 $t_E=-{\exp}[-(E_a/R)\;(1/T-1/T_{ref})]$로 정의되며, 임의의 온도 T에서 1일 동안에 일어난 품질변화는 표준온도 $T_{ref}$에서 몇일 동안에 일어난 변화에 상당하는가를 의미한다. 이와 같이 정의되는 표준온도 상당시간을 이용하여 glucose-lysine모델, 여러종류의 아미노산과 당의 액체모델 및 액체 음료 식품시스템의 실험자료로부터 비선형 최소자승법으로 kinetic parameter, n, $k_{ref}$$E_a$를 추정하였다. Glucose와 lysine의 손실속도는 1차 반응, 갈색물질 형성속도는 0차 반응이었다. 추정한 kinetic parameters를 이용하여 computer simulation한 결과 실험값과의 상관계수가 0.96 이상으로 잘 일치하여 $t_E$를 이용한 1단계 비선형 최소자승법으로 kinetic parameters를 효율적으로 정확히 추정할 수 있음을 확인하였다.

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Comparison of the Effects of Closed Kinetic Chain Exercise and Open Kinetic Chain Exercise According to the Shoulder Flexion Angle on Muscle Activation of Serratus Anterior and Upper Trapezius Muscles During Scapular Protraction

  • Park, Ju-jung;Chon, Seung-chul
    • 한국전문물리치료학회지
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    • 제24권4호
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    • pp.11-19
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    • 2017
  • Background: Methods for exercising serratus anterior (SA) and upper trapezius (UT) muscles are important for the recovery of patients with various shoulder disorders, yet the efficacy of closed or open kinetic chain exercises have not yet been evaluated. Objects: The purpose of this study was to compare the activation of the SA and UT muscles during scapular protraction considering both closed and open kinetic chain exercises. Methods: Thirty subjects were randomly divided into experimental groups (closed kinetic chain exercise) and control groups (open kinetic chain exercise) in which scapular protraction was performed at $90^{\circ}$ or $125^{\circ}$ shoulder flexion. Electromyographic activity data were collected from the SA and UT muscles per position and exercise method. Results: Separate mixed 2-way analysis of variance showed significant differences in the activation of the SA (F1,28=6.447, p=.017) and the UT (F1,28=35.450, p=.001) muscles between the groups at $90^{\circ}$ and $125^{\circ}$ shoulder flexion. Also, the SA/UT ratio measures at $90^{\circ}$ and $125^{\circ}$ shoulder flexion significantly differed between the groups (F1,28=15.457, p=.001). That is, the closed chain exercise was more effective than open chain exercise for strengthening the SA muscle and controlling the UT muscle, $125^{\circ}$ of shoulder joint was more effective than $90^{\circ}$. Conclusion: The findings suggest that scapular protraction with shoulder $125^{\circ}$ flexion at the closed kinetic chain exercise may be more effective in increasing SA muscle activation and decreasing UT muscle activation as well as increasing the SA/UT ratio than open kinetic chain exercise.

황 회수 공정 설계에서 부 반응의 영향 (The Impact of Side Reactions in Sulfur Recovery Unit Design)

  • 김성호;정원석;이희문;장근수
    • 플랜트 저널
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    • 제13권3호
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    • pp.36-46
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    • 2017
  • 황회수 공정의 연소반응기 안에서는 평형반응 및 kinetic 반응이 동시에 일어난다. 주요 kinetic 반응에 참여하는 성분들은 수소($H_2$), 일산화탄소(CO), 카보닐황화물(COS) 그리고 이황화탄소($CS_2$) 이다. 본 연구에서는 평형반응, 상관관계식(empirical correlations) 그리고 황 회수 공정의 라이센서 자료의 비교를 통해 반응기에서 kinetic components (COS와 $CS_2$)의 생성 양을 분석한다. 또한 kinetic components ($H_2$ 와 CO)의 생성 양의 분석을 통해 반응기에서의 생성 양과 온도와의 상관관계를 분석한다. 부 반응이 전체 연소에 필요로 하는 산소의 양에 어떤 영향을 미치는지도 같이 분석을 한다. 황회수 공정의 반응기내의 부 반응에 대한 충분한 이해는 전체 황회수 공정 설계를 할 때 최적의 장치 설계를 가능하게 하고 나아가 황회수 효율을 극대화 하는데 도움이 된다.

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이산화염소수 처리에 의한 주요 식중독균의 불활성화에 관한 두 kinetic models의 비교 (Evaluation of Two Kinetic Models on the Inactivation of Major Foodborne Pathogens by Aqueous Chlorine Dioxide Treatment)

  • 이지혜;송현정;송경빈
    • 한국식품저장유통학회지
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    • 제18권3호
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    • pp.423-428
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    • 2011
  • 주요 식중독균인 E. coli O157:H7, L monocytogenes, S. aureus, S. Typhimurium과 S. Enteritidis를 주어진 이산화염소수 농도에서 시간별로 처리한 inactivation data를 first-order kinetic model과 Weibull model을 이용하여 kinetic parameter를 비교, 분석하였다. 그 결과 Weibull model이 first-order kinetic model보다 inactivation kinetic data에 더 적합한 것을 보였다. 또한 특정 농도의 이산화염소수에서 처리한 survival plot의 tR values(특정 이산화염소수 농도에서 미생물 90%를 감소시키기 위해 필요한 시간)는 Weibull model을 적용 시, E. coli O157:H7가 5 ppm에서 2.49 min, L. monocytogenes가 5 ppm에서 1.47 min, S. aureus가 5 ppm에서 0.94 min, S. Typhimurium이 1 ppm에서 0.87 min 그리고 S. Enteritidis가 1 ppm에서 0.08 min으로 측정 되었다.

Stroke 변화가 Four-Valve SI 기관 실린더내 난류 운동에너지에 미치는 영향 (Effects of Stroke Change on Turbulent Kinetic Energy for the In-Cylinder Flow of a Four-Valve SI Engine)

  • 유성출
    • 한국가시화정보학회지
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    • 제9권4호
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    • pp.16-21
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    • 2011
  • The effects of stroke change on turbulent kinetic energy for the in-cylinder flow of a four-valve SI engine were studied. For this study, the same intake manifold, head, cylinder, and the piston were used to examine turbulence characteristics in two different strokes. In-cylinder flow measurements were conducted using three dimensional LDV system. The measurement method, which simultaneously collects 3-D velocity data, allowed a evaluation of turbulent kinetic energy inside a cylinder. High levels of turbulent kinetic energy were found in regions of high shear flow, attributed to the collisions of intake flows. These specific results support the more general conclusion that the inlet conditions play the dominant role in the generation of the turbulence fields during the intake stroke. However, in the absence of two counter rotating vortices, this intake generated turbulent kinetic energy continues to decrease but at a much faster rate.

COMBUSTION KINETICS OF POLYETHYLENE TEREPHTHALATE

  • Oh, Sea-Cheon;Lee, Dong-Gyu;Kwak, Hyun;Bae, Seong-Youl
    • Environmental Engineering Research
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    • 제11권5호
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    • pp.250-256
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    • 2006
  • The combustion kinetics of poly(ethylene terephthalate) (PET) was studied by the dynamic model which accounts for the thermal decomposition of polymer at any time. The kinetic analysis was performed by a conventional nonisothermal thermogravimetric (TG) technique at several heating rates between 10 and 40 K/min in air atmosphere. The thermal decomposition of PET in air atmosphere was found to be a complex process composed of at least two stages for which kinetic values can be calculated. The combustion kinetic analysis of PET gave apparent activation energy for the first stage of $257.3{\sim}269.9\;kJ/mol$, with a value of $140.5{\sim}213.8\;kJ/mol$ for the second stage. To verify the effectiveness of the kinetic analysis method used in this work, the kinetic analysis results were compared with those of various analytical methods. The kinetic parameters were also compared with values of the pyrolysis of PET in nitrogen atmosphere.

Design of Kinetic Typography Interaction based on the Structural Characteristics of Hangul

  • Lim, Sooyeon
    • International Journal of Contents
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    • 제12권3호
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    • pp.42-46
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    • 2016
  • Kinetic typography is technology such as color, scale, position of the letter changes dynamically with time and it communicates information with aesthetics and originality. The purpose of this study is to identify the design factors in the formativeness of Hangul and present and implement the interaction design method of unique Hangul kinetic typography based on the scientific structure of Hangul. We implemented the Hangul kinetic typography system, which varies in sizes and motion directions according to a viewer's movement and exhibited in a media art event. To do this, we used a viewer's skeleton information on typography synchronization. The results indicated that Hangul kinetic typography has potential not only as a means to communicate with viewers but also as a medium to show the artistic value of Hangul.

염료감응 태양전지용 루테늄 금속착체 염료의 이산화티타늄 전극에 대한 동적 흡착 연구 (Adsorption Kinetic Study of Ruthenium Complex Dyes onto TiO2 Anodes for Dye-sensitized Solar Cells (DSSCs))

  • 안병관
    • 한국전기전자재료학회논문지
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    • 제24권11호
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    • pp.929-934
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    • 2011
  • The adsorption kinetic study of ruthenium complex, N3, onto nanoporous titanium dioxide ($TiO_2$) photoanodes has been carried out by measuring dye uptake in-situ. Three simplified kinetic models including a pseudo first-order equation, pseudo second-order equation and intraparticle diffusion equation were chosen to follow the adsorption process. Kinetic parameters, rate constant, equilibrium adsorption capacities and related coefficient coefficients for each kinetic model were calculated and discussed. It was shown that the adsorption kinetics of N3 dye molecules onto porous $TiO_2$ obeys pseudo second-order kinetics with chemisorption being the rate determining step. Additionally the heterogeneous surface and the pore size distribution of porous $TiO_2$ adsorbents were also discussed.