• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.419-431
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• 1995

The common KIMI-Theory of Oriental medicine has evaluated clinical effects of herbal-drug based on KI, nature of berbs, and tastes. The KI in the theory consists of hotness, warm, cool and coldnes and also the Mi does five tastes such as sour, bitterness, sweet, spicy hotness and saltiness. However the KI does not mean thermal effect only. Thus we tried to determine skin and rectal temperatures at the same time for evaluating the relationship between KI and berbs. Male, adult Sprage-Dawly rat was chosen and berbal extract, 10g/Kg, was given orally once at 9:00 A.M. changes in rectal and skin temperatures were measured at 10, 30, 60, and 90 mins after the drug administratin. The changes in body temperatures are in greate deal of agreement of KI written in Herbology literatures.

• Membrane Journal
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• v.21 no.3
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• pp.213-221
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• 2011

Using poly(ethylene oxide) (PEO) as a polymer host, poly(ethylene glycol) (PEG) as a plasticizer, potassium iodide and iodine as sources of $I^-/I_3^-$, polymer electrolyte membranes were prepared. Based on the polymer electrolytes, solid-state dye-sensitized solar cell (DSSC)s were fabricated. The content of PEG in the electrolyte was controlled to be 95%. The mole number of KI per 1 mole of EO ([KI]/[EO] ratio) in the electrolyte was changed to be 0.022, 0.044, 0.066 and 0.088. The electrolyte membrane showed wax phase in ambient temperature. The ionic conductivity increased with increasing KI content to reach the maximum value at which [KI]/[EO] ratio is 0.066. After the maximum value, the ionic conductivity decreased with increasing KI content. In the case of DSSC, the Voc decreased continuously with increasing KI content in the polymeric electrolyte membrane. The $J_{SC}$ increased with increasing KI content to show maximum value at which [KI]/[EO] ratio is 0.044. In the higher KI content region, $J_{SC}$ value decreased with increasing KI content.

• Parasites, Hosts and Diseases
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• v.46 no.2
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• pp.105-108
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• 2008

Although the Korean isolate KI-1 of Toxoplasma gondii has been considered to be a virulent type I lineage because of its virulent clinical manifestations, its genotype is unclear. In the present study, genotyping of the KI-1 was performed by multilocus PCR-RFLP and microsatellite sequencing. For 9 genetic markers (c22-8, c29-2, L358, PK1, SAG2, SAG3, GRA6, BTUB, and Apico), the KI-1 and RH strains exhibited typical PCR-RFLP patterns identical to the type I strains. DNA sequencing of tandem repeats in 5 microsatellite markers (B17, B18, TUB2, W35, and TgM-A) of the KI-1 also revealed patterns characteristic of the type I. These results provide strong genetic evidence that KI-1 is a type I lineage of T. gondii.

• Journal of Sasang Constitutional Medicine
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• v.16 no.2
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• pp.128-133
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• 2004

Objectives Generally speaking, we could've not been used moxibustion to Soyangin. But we thought what matters is that which point is chosen, not that what method is chosen. So we had a case of moxibustion at Ki1 for a Soyangin patient with insomnia Methods We managed a patient with insomnia after intracranial hemorrhage. He had been undergone conservative therapy, herb medicine, acupuncture, sedatives. 20 days after admission we started to do moxibustion at both Ki 1 point(湧泉). We used artemisia and, the method was direct form. Results The duration and the quality of sleep of the patient was improved. After 10 days, he could sleep for 5 hours. Accompanied symptoms, as mentality, urination, and defication, was also improved. Conclusions From this case we could accept the efficacy of moxibustion at Ki 1 for Soyangin patient suffering from insomnia.

• Journal of Acupuncture Research
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• v.25 no.1
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• pp.107-120
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• 2008

Objectives : This study investigated the antioxidant effect of electro-acupuncture at $KI_6$ on rats treated with 2,2'-azobis(2-amidinopropane) dihydrochloride(AAPH). Methods : After electro-acupuncture at $KI_6$ on 48 rats that were given AAPH(50mg/kg) every day, the author observed several changes in weight, liver index, albumin, total bilirubin, LDL-cholesterol, LDH, glucose, GOT, GPT, SOD and catalase activity, and glutathione, NO, and MDA concentrations. Results : 1. In the $KI_6-EA$ group, the albumin level increased and LDL-cholesterol decreased compared with the control and holder groups. 2. In the $KI_6-EA$ group, SOD activity increased compared with the holder group, glutathione concentration increased compared with the control and holder groups, and catalase activity increased compared with the control group. 3. In the $KI_6-EA$ group, NO concentration decreased compared with the control and holder groups. Conclusions : This case shows that electro-acupuncture at $KI_6$ plays a significant antioxidant role by elevating defenses against cell toxicity caused by oxidative stress and suppressing oxidative injury.

• Korean Journal of Acupuncture
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• v.30 no.4
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• pp.281-288
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• 2013

Objectives : This study aimed to evaluate the effects of Stephaniae tetrandrae Radix Herbal-acupuncture(SR-HA) at KI10(Umgok) on nephritis induced by lipopolysaccharide(LPS) in rats. Methods : Male SD rats (n=32) were allocated to four groups; normal, LPS, saline, and SR-HA. The rats in the LPS, saline, and SR-HA groups were injected intra-peritoneally with LPS (2 mg/kg) to induce nephritis. The rats in the saline and SR-HA groups were treated with saline injection and SR-HA respectively at KI10 three times a week. To evaluate the effects of SR-HA at KI10 on nephritis in rats, the authors evaluated the numbers of WBC and neutrophils in blood, and the levels of creatinine, TNF-${\alpha}$, CINC-1 in serum, creatinine, total protein in urine and renal MPO. Results : SR-HA at KI10 significantly inhibited the increase of WBC and neutrophils in blood, TNF-${\alpha}$, CINC-1 in serum, creatine, total protein in urine and MPO in kidney of LPS-stimulated rats. Conclusions : SR-HA at KI10 may have therapeutic effects on nephritis in LPS-stimulated rats.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.4
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• pp.57-64
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• 2015

Objectives : To study correlation between Digital Infrared Thermal Imaging, Kupperman’s Index (KI) and Menopause Rating Scale (MRS) of Postmenopausal Women Methods : We analyzed 114 patients visiting Pohang Oriental Hospital from 1 ^st January 2014 to 30 ^th September 2015. The evaluating indexed of this trial were Age, DITI, KI, MRS. Temperature and different of temperature, such as In-dang (HN3), dan-Jung (CV17), gwan-won (CV4), hyup-back (LU4), no-gung (PC8), bock-to (ST31), and tae-chung (LR3). Results : Age was no correlation with DITI, KI, and MRS. There were positive correlation with KI and MRS significantly. DITI was not correlated with Age, KI and MRS, while ⊿T1 (LU4-PC8) was correlated with ⊿T2 (ST31-LR3) and ⊿T3 (CV17-CV4). Conclusions : There were non-significant correlation between DITI and Menopausal scale, but significant correlation in DITI themselves, Menopausal themselves. The More studies ar needed for the more accurate oriental medical diagnosis

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4815-4818
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• 2013

Background: Atrophic epithelium of cervix sampled from postmenopausal women may mimic high-grade cervical intraepithelial neoplasia in Papanicolaou-stained (Pap) smears. Ki-67 (MIB-1) protein presents on proliferating cells, and percentage of cells with positive nuclei provides a reliable tool for rapid evaluation of the growth fraction. The aim of this study was to determine the diagnostic value of protein Ki67 staining in atypical pap smears of postmenopausal women. Methods: In a case-control setting, pap smears of 75 women with an atypical pap smear (case group) and 75 with normal pap smears (controls) were obtained before and after estrogen treatment. Afterward, samples were exposed to the monoclonal antibody Ki-67 (MIB-1) and the immunohistochemically demonstrated Ki-67+ cells were compared. Results: Mean ages of cases and controls were $60.4{\pm}4.5$ and $59.9{\pm}4.3$ years respectively (P=0.50). There was one (2.7%) positive Ki-67 specimen in the case group, without any positive Ki-67 specimen in the control group (P=0.50). Conclusions: Measurement of proliferative activity index in Pap smears restrained with MIB1 is a simple, reliable, and cost-effective method for excluding negatives. This would imply that it might allow a substantial reduction of diagnostic estrogen courses and subsequent Pap smears in postmenopausal women with atypical findings.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2559-2564
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• 2016

Purpose: To compare Ki-67 index and microvessel density MVD) in multiple myeloma and non-myeloma patients and their correlation with each other and other prognostic markers. Materials and Methods: Forty patients were enrolled in this study between 2011-2013, 30 with multiple myelomas and 10 with non-malignant disease as controls. Proliferative activity was analyzed by Ki-67 and microvessel density (MVC) was assessed by CD34 and compared between two groups. In myeloma patients, correlation between Ki-67, MVD and other prognostic factors was assessed by Pearson correlation coefficient. Results: According to Durie Salmon staging criteria, 13 patients were of stage 1, 5 of stage II and 12 of stage III. Ki-67 expression showed a positive correlation with MVD (r=0.729, p<0.001) and was significantly higher (p<0.0001) in myeloma patients (range 35-80%, mean 60.1 %) as compared to controls (range 8-25%, mean 18.1%). $MVD/mm^2$ was also significantly (p<0.0001) higher in myeloma patients (range $62-237/mm^2$, mean $178.0/mm^2$) than controls (range $5.2-50/mm^2$, mean $18.3/mm^2$). Ki-67 and MVD, both increased progressively with increasing stage of myeloma. Ki-67 showed significant positive correlation with blood urea and lactate dehydrogenase and a significant negative correlation with serum albumin. MVD showed a significant positive correlation with blood urea, lactate dehydrogenase, serum creatinine, ${\beta}2$ microglobulin and skeletal lesions. Conclusions: Ki-67 and MVD are indicators of aggressiveness and poor prognosis having significant correlation with each other and other prognostic markers of multiple myeloma. Routine assessment of these markers may help to identify high risk patients, who may benefit from with more aggressive therapy.

• Journal of Korean Medical Ki-Gong Academy
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• v.1 no.1
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• pp.111-148
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• 1996

Recently, many study of the Kigong, but that is in the point of the view in Taoism and Ki itself. So, it thought that the study in comparison Kigong(Taoism) to Oriental Medicine is insufficient. I thought much of that there are many description of the movement and the effect in the the body in the old book written Taoism, Doinbub(Physical and breathing exercise), and that there are many relation 'the circulation of the Ki to 12 Jung-kyung(12 regular meridians). Then I give a report of the result that the study is compared in Taoism with in Oriental Medicine. The result were as follows ; 1. In the training of Doinbub, the effect is regulating muscle and skeleton, promote wi(constructive) system and ki(superficial) system, promote the ki and blood, strengthen the body resistance and dispel the invading pathogenic factors and preventive treatment. 2. In the training of Doinbub, the movements were much related to 12 regular Meridians and Muscles along the 12 meridians. 3. In the training of Doinbub, the effect were much related to 12 regular Meridians and Muscles along the 12 meridians. 4. It is possible that we set pathological syndrome to Doinbub(Physical and breathing exercise).