• Journal of Oral Medicine and Pain
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• v.30 no.1
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• pp.15-23
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• 2005

Mucin glycoproteins are the primary carriers of the oligosaccharide moieties that constitute the blood group substances in human saliva. The aim of this study was to determine whether or not the conversion of either the A or B blood group antigens to the H antigen can occur during the degradation process of stored saliva samples. Forty subjects (20 subjects in each A and B blood group) identified as secretors were enrolled in this study. Fresh whole saliva samples and their clarified supernatants were stored at room temperature for 1 week. The conversion of the blood group antigens was detected by SDS-PAGE and immunoblotting. Among the subjects showing the conversion in whole saliva, glandular saliva samples were obtained from 8 subjects (4 subjects in each A and B blood group). Submandibular-sublingual saliva (SMSL) and a mixture of SMSL and parotid saliva (PS) were stored at room temperature for 1 week. The conversion of the blood group antigens was detected by the same method. The obtained results were as follows: 1. In the clarified samples of whole saliva, the A antigen was detected as being either intact (5%) or degraded molecules (95%) after the 1 week period. Conversion of the A antigen to the H antigen was detected in 5 subjects (25%). In the unclarified samples, the A antigen was either detected as degraded molecules (90%) or was not detected (10%). Conversion of the antigen had occurred in 4 subjects (20%). 2. In the clarified samples of whole saliva, the B antigen was detected as intact (20%) or as degraded molecules (65%) or was not detected (15%) after the 1 week period. Conversion of the B antigen to the H antigen was detected in 7 subjects (35%). In the unclarified samples, the B antigen was detected as intact (5%) or as degraded molecules (65%), or was not detected (30%). Conversion of the antigen was observed in 2 subjects (10%). 3. In the glandular saliva samples, only one of the four subjects displayed an antigenic conversion from the A to H antigen or from the B to H antigen. The conversion had occurred in both the SMSL samples and the SMSL and PS mixture. No degradation of the antigens was detected in the other three samples of the A or B blood groups, nor was there any conversion. The results demonstrated that conversion of the blood group antigens could occur in saliva, and suggested that the enzymes responsible for the conversion are present in saliva. Further studies on the origin and activity of the specific glycosidases in saliva as well as quantitative measurements of the antigenic conversion will be needed.

• Journal of Broadcast Engineering
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• v.20 no.2
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• pp.215-223
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• 2015

Energy harvesting technique is an energy charging technique for communication device in energy-constrained environment. Recently, energy harvesting technique that harvests energy from wireless radio frequency signal is proposed. Representatively, there are time switching technique and power splitting technique. This paper proposes an optimal harvesting time allocation scheme in a wireless cognitive relay network when secondary user relay uses energy harvesting technique to transmit information. Secondary user relay receives information and energy simultaneously from the secondary user source's signal via time switching technique. We aim to maximize the instantaneous throughput by optimizing harvesting time of the secondary user relay. Simulation results show that using optimized harvesting time gets larger instantaneous throughput compared to using constant harvesting time.

• Journal of the Korean Society of Clothing and Textiles
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• v.2 no.1
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• pp.167-176
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• 1978

The effect of additives in final rinse water during laundering on soiling, soil removal and some properties of fabrics has been studied with various fabrics. The additives examined were fabric softener (Sta-Puf), cationic surfactant (Apole PS), sizing materials such as CMC, PYA, cornstarch and mixture of CMC and cationic surfactant. The results obtained may be summerized as follows. L Addition of additives except PVA in final rinse water generally reduce the deposition of carbon-$CCl_4$ soil and it seems to be rather independant of the concentration of additives. The effect of additives on soil resistant is found to increase in the following order. cotton; Apole

• Journal of Digital Convergence
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• v.16 no.2
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• pp.479-488
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• 2018

To develop and test validity and reliability of Korean version of the Student Perception of Patient Safety Knowledge, Skills, Attitudes to assess applicability for nursing students. Survey data were collected from convenience sample of 425 fourth year nursing students who enrolled in four universities. Data were evaluated using item analysis, content validity, exploratory factor analysis, and Cronbach's alpha. The attitudes scale was eliminated since item-total correlations were less than .3, on the final Korean Version Scales. The attitudes subscale needs further refinement before implementation. The finding out this study demonstrate that the knowledge and skills scales showed satisfactory validity and reliability. It is useful to evaluate nursing students during educational preparation and in practice.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.3
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• pp.246-252
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• 2014

This study is on the development of 150PS inboard type of compact water jet propulsion system. The water jet is composed of intake, impeller, diffuser, reverse bucket and main shaft. Components of water jet have been manufactured through precision processing after sand casting. Development of water jet propelled engine has been finally completed by processes which are design, production and inspection on each component. The water jet performance characteristics show that 0.29 m3/s of maximum flow rate and 37 m/s of flow velocity have been secured in the ground test pool. Field test was performed by 21ft test ship that water jet propulsion equipment developed in this study was installed. As a result, the weight of hull, engine and other parts of the ship has been almost 1.2 ton and 45 km/h of maximum sailing speed has been recorded with 3700 rpm of engine in the domestic coast test.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.2
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• pp.22-30
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• 2017

PL (Product Liability) refers to the legal responsibility of a manufacturer or seller for bodily injuries or property losses caused by product defects. Therefore, it is important for companies to construct a product liability response system that strategically manage and effectively adapt to product liability. A PL response system refers to companywide operations of PL prevention (PLP) measures, product safety (PS) measures, and PL defense (PLD) measures appropriate for a company's scale and environment. To establish an enterprise product liability response system, each essential component of corporations should be systematically operated and maintained considering the scale and characteristics of the corporations. Essential components of PL response system is Strategy, Organization, Training, Technology, Investment, and Awareness. Role of essential components is that companies need specific strategies to secure product safety and protect customers from product defects, and appropriate organizations must be composed for effective operation of such strategies. The objective of this paper seeks to examine the relationships among the essential components of the product liability response system and PL performance. PL performance consists of positive performance and negative performance. In particular, positive performance include increased efforts in product or process innovation such as strengthening research and development (R&D) to produce safer products without defects. In order to carry out this research we obtained 98 questionnaire of manufacturing company. A summary of the analyses is as follows: First, the awareness and technology among essential components affect significantly to the positive performance. Second, the awareness and strategy among essential components negative affect to the negative performance.

• Archives of Pharmacal Research
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• v.22 no.2
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• pp.165-172
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• 1999

In the present work , the transport mechanism of a capsaicin derivative, DA-5018, through blood-brain barrier (BBB) has been investigated to evaluate the feasibility of potential drug development. The result of pharmacokinetic parameters obtained from the intravenous injection of plasma volume marker,$[3^H]RSA$ and $[{14}^C]DA-5018$, indicated that both AUC, area under the plasma concentration curve and VD, volume of distribution in brain of $[3^H]RSA$ agreed with those reported ($1620{\pm}10 $percentage injected dose minute per milliliter (%IDmin/ml) and $12.0{\pm}0.1{\mu}l/g$, respectively). Elimination half-life and AUC of $[{14}^C]DA-5018$is corrected by the PHLC analysis, 19.6$\pm$1.2 min and 7.69$\pm$0.85% IDmin/ml, respectively. The metabolic rate of $[{14}^C]DA-5018$was very rapid. The blood-brain barrier permeability surface area (PS) product of $[{14}^C]DA-5018$ was calculated to be 0.24$\pm$0.05 $\mu$l/min/g. The result of internal carotid artery perfusion and capillary depletion suggested that [14C]DA-5018 pass through BBB with the time increasingly. Investigation of transport mechanism of $[{14}^C]DA-5018$ using agonist and antagonist suggested that vanilloid (capsaicin) receptor did not exist in the BBB, and nutrient carrier system in the BBB has no effect on the transport of DA-5018. In conclusion, despite the fact that penetration of DA-5018 through BBB is significant, the intact drug found in the brain tissue is small because of a rapid metabolism. Therefore, for the central analgesic effect of DA-5018, the method to increase the metabolic stability in plasma and the brain permeability should be considered.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6621-6626
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• 2015

Purpose: To evaluate effects of metformin on clinical outcome of non-diabetic patients with stage IV NSCLC. Materials and Methods: A prospective, randomized, open-label, controlled pilot study was conducted on patients with stage IV NSCLC with an Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0-2, excluding patients with diabetes and lactic acidosis. Thirty chemo-$na\ddot{i}ve$, non-diabetic patients with stage IV NSCLC were enrolled. Fifteen patients received intravenous gemcitabine/cisplatin regimen alone (arm B) while fifteen patients received the same regimen plus daily oral metformin 500mg (arm A). The effect of metformin on chemotherapy-response rates, survival, and adverse events in these patients was evaluated. Results: Objective response rate (ORR) and median overall survival (OS) in arms A and B were 46.7% versus 13.3% respectively, p=0.109 and 12 months versus 6.5 months, respectively, p=0.119. Median progression free survival (PFS) in arms A and B was 5.5 months versus 5 months, p=0.062. No significant increase in toxicity was observed in arm A versus arm B. Percentage of patients who experienced nausea was significantly lower in arm A versus arm B, at 26.7% versus 66.7% respectively, p=0.028. Conclusions: Metformin administration reduced occurrence of chemotherapy induced-nausea. Non-statistically significant improvements in the ORR or OS were observed. Metformin had no effect on PFS.

• Journal of Korea Foresty Energy
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• v.7 no.1
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• pp.28-36
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• 1987

To know the possibility of fuel substitution for Diesel engine with the seed oil of Evodia daniellii, which is one of the native oil seed trees in Korea. the refined seed oil mixed with light oil in the various rates was tested in the 8 PS Diesel engine: the output, the fuel consumption rate, the governor performance, the rpm stability in the total loading condition. the content of graphite in the burned gas, and the traction coefficients at the different gear stages were maintained The following results were discussed. 1. The output at the normal revolution (2200rpm)was increased as the percent seed oil increased. At the lower rpm (2000-1500rpm )there were no consistent difference in the outputs among fuels of the different percent seed oil 2. The rate of fuel consumption was inclosed as the percent seed oil increased in each loading condition. 3. The more percent sud oil was mixed in the fuel. the better governor performance appeared at both the instantaneous and stable speed. 4. The more percent seed oil was mixed In the fuel, the more stable rpm ratio was maintained 5. The graphite content In the burned gas was increased as the load increased, but there was no apparent difference in the content at each load among the 100$\%$ seed oil, the 100$\%$ light oil, and the mixtures in various rates. 6. In all fuel mixtures the maximam traction coefficent appeared at the third transmission gear stage. Generally in over all transmission gear stages the fuel mixtures of the seed oil:light oil ratio from 7:3 to 5:5 resulted greater traction force than the other fuels.

• Korean Journal of Food Science and Technology
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• v.16 no.3
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• pp.267-272
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• 1984

${\beta}-Fructofuranosidase$ was immobilized covalently on the oxidized microbial wall of a Penicillium spp. 'PS-8', which is totally different from the conventional whole cell immobilization in concept. The immobilization of ${\beta}-fructofuranosidase$ by a series of treatments; oxidation of microbial cells with sodium metaperiodate, enzyme loading on the oxidized cells, extrusion, and crosslinking induced by glutaradehyde, were carried out. The final product had a good mechanical strength and showed 26% of the applied enzyme activity. The specific activity was 750 units per g of the dry cell product. The immobilized enzyme showed the kinetic parameters as follows; optimum pH at 5, optimum temperature at $55^{\circ}C$, activation energy of 19 kJ $mol^{-1}$, and apparent Km of 55 mM.