• Title/Summary/Keyword: K-neat

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Upregulation and Clinicopathological Significance of Long Non-coding NEAT1 RNA in NSCLC Tissues

  • Pan, Lin-Jiang;Zhong, Teng-Fei;Tang, Rui-Xue;Li, Ping;Dang, Yi-Wu;Huang, Su-Ning;Chen, Gang
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2851-2855
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    • 2015
  • Background: Recent reports have shown that nuclear enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), contributes to the precise control of gene expression and is related to several human malignancies. However, limited data are available on the expression and function of NEAT1 in lung cancer. The major objective of the current study was to profile the expression and clinicopathological significance of NEAT1 in non-small cell lung cancers (NSCLCs). Materials and Methods: NEAT1 expression in 125 NSCLC cases and paired adjacent non-cancer tissues was assessed by real-time quantitative reverse transcription-PCR (qRT-PCR). Relationships between NEAT1 and clinicopathological factors were also investigated. Results: The relative level of NEAT1 was $6.98{\pm}3.74$ in NSCLC tissues, significantly elevated as compared to that of the adjacent non-cancer lung tissues ($4.83{\pm}2.98$, p<0.001). The area under curve (AUC) of high expression of NEAT1 to diagnose NSCLC was 0.684 (95% CI: 0.619~0.750, p<0.001). NEAT1 expression was positively correlated with patient age (r=-2.007, p=0.047), lymphatic metastasis (r=-2.731, p=0.007), vascular invasion (r=-3.617, p=0.001) and clinical TNM stage (r=-4.134, p<0.001). Conclusions: This study indicates that NEAT1 might be associated with oncogenesis and progression in NSCLC, and suggests application in molecular targeted therapy.

Isoconversional Cure Kinetics of Modified Urea-Formaldehyde Resins with Additives

  • Park, Byung-Dae
    • Current Research on Agriculture and Life Sciences
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    • v.30 no.1
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    • pp.41-50
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    • 2012
  • As a part of abating formaldehyde emission of urea-formaldehyde resin, this study was conducted to investigate the rmalcure kinetics of both neat and modified urea-formaldehyde resins using differential scanning calorimetry. Neat urea-formaldehyde resins with three different formaldehyde/urea mol ratios (1.4, 1.2 and 1.0) were modified by adding three different additives (sodium bisulfite, sodium hydrosulfite and acrylamide) at two different levels (1 and 3wt%). An isoconversional method at four different heating rates was employed to characterize thermal cure kinetics of these urea-formaldehyde resins to obtain activation energy ($E{\alpha}$) dependent on the degree of conversion (${\alpha}$). The $E{\alpha}$ values of neat urea-formaldehyde resins (formaldehyde/urea = 1.4 and 1.2) consistently changed as the ${\alpha}$ increased. Neat and modified urea-formaldehyde resins of these two F/U mol ratios did show a decrease of the $E{\alpha}$ at the final stage of the conversion while the $E{\alpha}$ of neat urea-formaldehyde resin (formaldehyde/urea = 1.0) increased as the ${\alpha}$ increased, indicating the presence of incomplete cure. However, the change of the $E{\alpha}$ values of all urea-formaldehyde resins was consistent to that of the Ea values. The isoconversional method indicated that thermal cure kinetics of neat and modified urea-formaldehyde resins showed a strong dependence on the resin viscosity as well as diffusion control reaction at the final stage of the conversion.

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Frequency Analysis of Adaptive Behavior of NEAT based Control for Snake Modular Robot (뱀형 모듈라 로봇을 위한 NEAT 기반 제어의 적응성에 대한 주파수 분석)

  • Lee, Jaemin;Seo, Kisung
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.9
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    • pp.1356-1362
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    • 2015
  • Modular snake-like robots are robust for failure and have flexible locomotions for obstacle environment than of walking robot. This requires an adaptation capability which is obtained from a learning approach, but has not been analysed as well. In order to investigate the property of adaptation of locomotion for different terrains, NEAT controllers are trained for a flat terrain and tested for obstacle terrains. The input and output characteristics of the adaptation for the neural network controller are analyzed for different terrains in frequency domain.

The visual Effect by physical and clothes design of the mid-aged Korean and American women(II) -Focusing on the psychological visual effects- (한국과 미국 중년 여성의 체형과 의복디자인에 따른 시각효과(II) - 심리적 시각효과를 중심으로 -)

  • Park, Soon-Chun;O'rourke-Kaplan, Marian
    • Fashion & Textile Research Journal
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    • v.11 no.3
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    • pp.371-382
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    • 2009
  • In this study, I examined the psychological visual effect and clothes preference by clothes designs for the mid-aged Korean and American women's somatotypes. The psychological visual effects of each somatotypes' clothes are like these. First, the primary factors for psychological visual effect were analyzed into 5, neat, feminine, polished, modern and active. Second, in thin somatotype, Korean evaluated that china collar and V-neckline are the least feminine, and stand collar is the most polished and the modernest. American evaluated that V-neckline is the most feminine, and tailored collar is the modernest. It shows that there's the difference of culture. In standard somatotype, Korean thought stand collar with pants is the neatest, but tailored collar and china collar with pants are not neat. Contrary, they thought tailored collar with skirt is the neatest and stand collar with skirt is not neat. American thought tailored collar with skirt is the neatest and modernest. The neat visual effects are evaluated differently according to the clothes' styles of bottom. In obesity, Korean evaluated that tailored collar with skirt is the neatest and modernest, but stand collar with skirt is not modern. Stand collar with pants is the modernest, but tailored collar with pants is the least modern and active. American evaluated that round neckline with pants is not neat, modern and active, and round neckline with skirt is the modernest and the most active. So neckline's visual effects are differently showed by culture and the clothes' styles of bottom.

A blueprint for designing and developing the listening and the reading test of National English Ability Test (NEAT): Item-types decision-making model (국가영어능력평가시험(NEAT)의 검사지 구성의 원칙과 절차: 문항 유형 확정 모델)

  • Kim, Yong-Myeong
    • English Language & Literature Teaching
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    • v.16 no.4
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    • pp.153-184
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    • 2010
  • On the bases of the 5 principles and the 4 criteria for designing and developing of the listening and the reading test of National English Ability Test (NEAT), this study presents Item-Types Decision-Making Model as a blueprint for designing and constructing the two tests. It sets up the criteria for validating item types, designs a modular type of test specifications, constructs an item-types bank, and specifies a complementary type of test specifications of the two tests. To gather all these threads up, it constructs Item-Types Decision-Making Model which consists of such components as the item-type pool, the validity criteria and the procedures of testing item types, the item-types bank, the modular and the complementary type test specification. Thus, it shows how the Model works in developing and constructing the two level-differentiated listening and reading tests (the 2nd and the 3rd rank) of NEAT. Finally, it discusses some implications and applications of the Model to the two level-differentiated tests (the A and the B type) of 2014 CSAT (College Scholastic Ability Test) systems, National Assessment of Educational Achievement (NAEA), and classroom testing. In conclusion, Item-Types Decision-Making Model functions as a testing template in an item development system and as a matrix in an item-types bank system.

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Non-energy Use and $CO_2$ Emissions: NEAT Results for Korea

  • Park, Hi-chun
    • Journal of Energy Engineering
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    • v.11 no.1
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    • pp.34-46
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    • 2002
  • Carbon accounting is a key issue in the discussions on global warming/CO$_2$mitigation. This paper applies both the IPCC Approach and the NEAT (Non-Energy use Emission Accounting Tables) model, a bottom-up approach, to estimate the potential CO$_2$ emissions (carbon storage) originating from the non-energy use as to assess the actual CO$_2$ emissions (carbon release) from the use of fossil fuels in Korea. The current Korean carbon accounting seems to overestimate the potential CO$_2$ emissions and with it to underestimate the actual CO$_2$ emissions. The estimation shows that the potential CO$_2$ emissions calculated according to the IPCC Approach are lower than those calculated using the NEAT model. This is because the IPCC default storage fraction for naphtha seems to be low for the Korean petrochemical production structure, on the one hand and because the IPCC Approach does not consider the trade with short life petrochemical products, on the other hand. This paper shows that a bottom-up approach like the NEAT model can contribute to overcome some of limitations of the IPCC guidelines, especially by considering the international trade with short life petrochemical products and by estimating the storage fractions of fossil fuels used as feedstocks for the country in consideration. This paper emphasizes the importance of accurate energy statistics for carbon accounting.

Cure Kinetics of Cycloaliphatic Epoxy/Silica System for Electrical Insulation Materials in Outdoor Applications

  • Lee, Jae-Young;Park, Jae-Jun;Kim, Jae-Seol;Shin, Seong-Sik;Yoon, Chan-Young;Cheong, Jong-Hoon;Kim, Young-Woo;Kang, Geun-Bae
    • Transactions on Electrical and Electronic Materials
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    • v.16 no.2
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    • pp.74-77
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    • 2015
  • The cure kinetics of a neat epoxy system and epoxy/silica composite were investigated by DSC analysis. A cycloaliphatic type epoxy resin was diglycidyl 1,2-cyclohexanedicarboxylate and curing agent was anhydride type. To estimate kinetic parameters, the Kissinger equation was used. The activation energy of the neat epoxy system was 88.9 kJ/mol and pre-exponential factor was 2.64×1012 min−1, while the activation energy and pre-exponential factor for epoxy/silica composite were 97.4 kJ/mol and 9.21×1012 min−1, respectively. These values showed that the silica particles have effects on the cure kinetics of the neat epoxy matrix.

PHOTOCHEMICAL REACTION OF CHLOROFORM

  • Park, Hyoung-Ryun;Jeong, Young-Tae;Ko, Song-Kyong;Oh, Jong-Hoon;Ham, Heui-Suk
    • Journal of Photoscience
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    • v.4 no.1
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    • pp.17-21
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    • 1997
  • The photochemical reactions of the neat chloroform and the aqueous chloroform in the absence (saturated with argon) and presence of 02 (saturated with air or oxygen) have been investigated using 184.9 nm UV light. The irradiation of the deoxygenated neat chloroform causes the formation of hexachloroethane, pentachloroethane, and 1, 1, 2, 2-tetrachloroethane. The initial quantum yields of the products were determined to be 6.37 x 10$^{-4}$, 4.04 x 10$^{-4}$ and 1.76 x 10$^{-4}$, respectively. In the irradiation of aqueous chloroform, chloride ion was also formed along with the products listed above and 1, 1, 2, 2-tetrachloroethane was the predominant product among the chlorinated organic products, which contrasts to the case of the neat chloroform. The presence of oxygen during the irradiation of aqueous chloroform had an effect on the yield of the products. With increasing the concentration of oxygen, the formation of the products was decreased. Probable reaction mechanisms for the photochemical reaction were presented on the basis of products analysis.

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Neat Synthesis and Anti-oxidant Activity of α-Hydroxyphosphonates

  • Rao, K. Uma Maheswara;Sundar, Ch. Syama;Prasad, S. Siva;Rani, C. Radha;Reddy, C. Suresh
    • Bulletin of the Korean Chemical Society
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    • v.32 no.9
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    • pp.3343-3347
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    • 2011
  • A simple efficient and neat synthesis of ${\alpha}$-hydroxy phosphonates has been accomplished from aromatic/heterocyclic aldehydes and diethyl phosphite using $KHSO_4$ as a catalyst under solvent-free conditions at ambient temperature. These compounds are characterized by spectral and analytical data and tested for their anti-oxidant activity.

FUEL PROPERTIES AND EMISSIONS CHARACTERISTICS OF ETHANOL-DIESEL BLEND ON SMALL DIESEL ENGINE

  • Xu, B.Y.;Qi, Y.L.;Zhang, W.B.;Cai, S.L.
    • International Journal of Automotive Technology
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    • v.8 no.1
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    • pp.9-18
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    • 2007
  • Phase separation and low cetane number are the main barriers to the large-scale use of ethanol-diesel blend fuel on small diesel engines. In this paper, an additive package is designed on the basis of the blended fuel properties to overcome these limitations. The experiments show that the solubility of ethanol in diesel is evidently increased by adding $1{\sim}2%$ (in volume) of the additive package and the flammability of ethanol-diesel blend fuel with the additive has reached the neat diesel level under the cold start conditions. Effects of the ethanol content in diesel on fuel economy, combustion characteristics, and emission characteristics are also investigated with the ethanol blend ratios of 10%, 20% and 30%. The increase in ethanol content shows that the specific fuel consumption and the brake thermal efficiency are both gradually increased compared to neat diesel. The soot concentrations of the three blended fuels are all greatly lower than that of neat diesel. $NO_x$ emission is increased with an increase in the engine load and is reduced with the increase in the ethanol blend ratio under a high load.