• Title/Summary/Keyword: K-mismatch

Search Result 896, Processing Time 0.034 seconds

STUDY OF MULTILAYER STRUCTURE USING X-RAY DOUBLE CRYSTAL DIFFRACTION

  • Wu, Yunzhong;Xu, Xueming;Wang, Weiyuan
    • Journal of the Korean Vacuum Society
    • /
    • v.4 no.S2
    • /
    • pp.30-33
    • /
    • 1995
  • By using X-ray double crystal diffraction technique the multilayer structure composed of glass membrane, platinum film and $\alpha Al_2O_3$ substrate has been studied. It is found the stress is produced in the film by thermal mismatch within multilayer materials. The measuring results of thin film platinum resistors show that the stress were induce resistance change of device and different stress status will produce add resistance in different direction. Selecting proper glass material can make opposite stress in Pt film and opposite add resistance due to thermal mismatch. The reliability of Pt resistor has been improved with method of this stress compensation.

  • PDF

Lattice strain effects on superconductivity in $La_{2-x}Sr_{x}CuO_{4}$ single-crystalline films grown by IR-LPE technique

  • Tanaka, I.;Islam, A.T.M.N.;Wataudhi, S.
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.13 no.4
    • /
    • pp.172-175
    • /
    • 2003
  • We have investigated effects of the lattice mismatch between the LPE films and the substrates. We have grown $La_{2-x}Sr_{x}CuO_{4}$(x=0.1 to 0.15) single crystalline films on single crystalline substrates having different lattice parameter ratio c/a e.g., $La_{2-x}Sr_{x}Cu_{1-y}Zn_{y}O_{4},\;La_{2-x}Ba_{x}CuO_{4},\; LaSrAlO_{4}\;and\;La_{2-x}Sr_{x}Cu_{1-y}Al_{y}O_{4}$ etc., using the IR-LPE technique. The superconducting properties of the grown films were found to vary significantly depending on the lattice mismatch with different substrates.

Sporadic Early Onset Colorectal Cancer in Pakistan: a Case-Control Analysis of Microsatellite Instability

  • Siddique, Sabeehuddin;Tariq, Kanwal;Rafiq, Sobia;Raheem, Ahmed;Ahmed, Rashida;Shabbir-Moosajee, Munira;Ghias, Kulsoom
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.5
    • /
    • pp.2587-2592
    • /
    • 2016
  • Background: Early onset sporadic colorectal cancer (CRC) is a biologically and clinically distinct entity hypothesized to exhibit differences in histological features and microsatellite instability (MSI) as compared to typical onset CRC. This study compared the MSI status, mismatch repair enzyme deficiency and clinicopathological features of early onset (aged ${\leq}45$ years) with controls (>45 years). Materials and Methods: A total of 30 cases and 30 controls were analyzed for MSI status using the Bethesda marker panel. Using antibodies against hMLH1, hMSH2 and hMSH6, mismatch repair protein expression was assessed by immunohistochemistry. Molecular characteristics were correlated with clinicopathological features. Results: The early onset sporadic CRCs were significantly more poorly differentiated tumors, with higher N2 nodal involvement and greater frequency of signet ring phenotype than the typical onset cases. MSI was observed in 18/30 cases, with 12/18 designated as MSI-high (MSI-H) and 6/18 designated as MSI-low (MSI-L). In the control group, 14 patients exhibited MSI, with 7 MSI-H and 7 MSI-L. MSI tumors in both cases and controls exhibited loss of hMLH1, hMSH2 and hMSH6. MSS tumors did not exhibit loss of expression of MMR proteins, except hMLH1 protein in 3 controls. No statistically significant difference was noted in MSI status or expression of MMR proteins in cases versus controls. Conclusions: Microsatellite status is comparable between early and typical onset sporadic CRC patients in Pakistan suggesting that differences in clinicopathological features between these two subsets are attributable to other molecular mechanisms.

Colorectal Carcinoma in Malaysians: DNA Mismatch Repair Pattern in a Multiethnic Population

  • Cheah, Phaik-Leng;Looi, Lai-Meng;Teoh, Kean-Hooi;Rahman, Nazarina Abdul;Wong, Li-Xuan;Tan, Soo-Yong
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.7
    • /
    • pp.3287-3291
    • /
    • 2014
  • Background: The interesting preponderance of Chinese with colorectal carcinoma (CRC) amongst the three major ethnic groups in Malaysia prompted a study to determine DNA mismatch repair (MMR) status in our CRC and attempt correlation with patient age, gender and ethnicity as well as location, grade, histological type and stage of tumour. Histologically re-confirmed CRC, diagnosed between $1^{st} $January 2005 and $31^{st}$ December 2007 at the Department of Pathology, University of Malaya Medical Centre, were immunohistochemically stained with monoclonal antibodies to MMR proteins, MLH1, MSH2, MSH6 and PMS2 on the Ventana Benchmark XT autostainer. Of the 142 CRC cases entered into the study, there were 82 males and 60 females (M:F=1.4:1). Ethnically, 81 (57.0%) were Chinese, 32 (22.5%) Malays and 29 (20.4%) Indians. The patient ages ranged between 15-87 years (mean=62.4 years) with 21 cases <50-years and 121 ${\geq}50$-years of age. 14 (9.9%) CRC showed deficient MMR (dMMR). Concurrent loss of MLH1 and PMS2 occurred in 10, MSH2 and MSH6 in 2 with isolated loss of MSH6 in 1 and PMS2 in 1. dMMR was noted less frequently amongst the Chinese (6.2%) in comparison with their combined Malay and Indian counterparts (14.8%), and was associated with right sided and poorly differentiated tumours (p<0.05). 3 of the 5 (60.0%) dMMR CRC cases amongst the Chinese and 1 of 9 cases (11.1%) amongst the combined Malay and Indian group were <50-years of age. No significant association of dMMR was noted with patient age and gender, tumour stage or mucinous type.

Electric Circuit Analysis for PV Array on Short-Circuit Failure of Bypass Diode in PV Module (PV모듈의 바이패스 다이오드 단락 고장 시 태양광어레이 회로 특성분석)

  • Lee, Chung-Geun;Shin, Woo-Gyun;Lim, Jong Rok;Hwang, Hye-Mi;Ju, Young-Chul;Jung, Young-Seok;Kang, Gi-Hwan;Chang, Hyo-Sik;Ko, Suk-Whan
    • Journal of the Korean Solar Energy Society
    • /
    • v.39 no.6
    • /
    • pp.15-25
    • /
    • 2019
  • As the installation of photovoltaic systems increases, fire accidents of PV system grow every year. Most of PV system fires have been reported to be caused by electrical components. The majority of fire accidents occurred in combiner box, which is presumed to be short-circuit accidents due to dustproof and waterproof failures or heat deterioration of blocking diode. For this reason, the blocking diode installation became optional by revised PV combiner regulation. In this paper, according to the revised regulation, reverse current that generated by voltage mismatch was measured and analyzed in PV array without a blocking diode. The factors that cause voltage mismatch in array are assumed to be shaded PV module and short circuit failure of bypass diode. As the result of experiment, there is no reverse current to flow under shading condition in module, but reverse current flows on the failure of bypass diode in module. According to the module's I-V characteristic curve analysis, open voltage was slightly reduced due to operation of bypass diode in shading. However, it showed that open circuit voltage has decreased significantly in the failure of bypass diode. This indicates that the difference in open voltage reduction of voltage mismatch factor causes reverse current to flow.

Association between Mismatch Repair Gene MSH3 codons 1036 and 222 Polymorphisms and Sporadic Prostate Cancer in the Iranian Population

  • Jafary, Fariba;Salehi, Mansoor;Sedghi, Maryam;Nouri, Nayereh;Jafary, Farzaneh;Sadeghi, Farzaneh;Motamedi, Shima;Talebi, Maede
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.12
    • /
    • pp.6055-6057
    • /
    • 2012
  • The mismatch repair system (MMR) is a post-replicative DNA repair mechanism whose defects can lead to cancer. The MSH3 protein is an essential component of the system. We postulated that MSH3 gene polymorphisms might therefore be associated with prostate cancer (PC). We studied MSH3 codon 222 and MSH3 codon 1036 polymorphisms in a group of Iranian sporadic PC patients. A total of 60 controls and 18 patients were assessed using the polymerase chain reaction and single strand conformational polymorphism. For comparing the genotype frequencies of patients and controls the chi-square test was applied. The obtained result indicated that there was significantly association between G/A genotype of MSH3 codon 222 and G/G genotype of MSH3 codon 1036 with an increased PC risk (P=0.012 and P=0.02 respectively). Our results demonstrated that MSH3 codon 222 and MSH3 codon 1036 polymorphisms may be risk factors for sporadic prostate cancer in the Iranian population.

Load Insensitivity Analysis of Balanced Power Amplifier for W-CDMA Handset Applications (W-CDMA 단말기용 Balanced 전력증폭기의 Load Insensitivity 분석)

  • Kim, Un-Ha;Kang, Sung-Yoon;Cheon, Clifford D.Y.;Kwon, Young-Woo;Kim, Jung-Hyun
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.23 no.1
    • /
    • pp.68-75
    • /
    • 2012
  • The load-insensitivity of the balanced power amplifier(PA) for W-CDMA handset applications is analyzed. The load impedances of the two parallel amplifiers in the balanced PA depending on the output load mismatch are mathematically calculated and with the result, the phase of reflection coefficient at which the linear output power is severely degraded is investigated. From the analysis, we proposed that the linearity of the balanced PA at the phase can be improved by properly increasing the transistor size and thus, multiple balanced PA's with different transistor size are designed and simulated. The simulation result showed that the balanced PA with larger transistor size has improved linear output power under VSWR=4:1.

Wind tunnel modeling of roof pressure and turbulence effects on the TTU test building

  • Bienkiewicz, Bogusz;Ham, Hee J.
    • Wind and Structures
    • /
    • v.6 no.2
    • /
    • pp.91-106
    • /
    • 2003
  • The paper presents the results of 1:50 geometrical scale laboratory modeling of wind-induced point pressure on the roof of the Texas Tech University (TTU) test building. The nominal (prevalent at the TTU site) wind and two bounding (low and high turbulence) flows were simulated in a boundary-layer wind tunnel at Colorado State University. The results showed significant increase in the pressure peak and standard deviation with an increase in the flow turbulence. It was concluded that the roof mid-plane pressure sensitivity to the turbulence intensity was the cause of the previously reported field-laboratory mismatch of the fluctuating pressure, for wind normal and $30^{\circ}$-off normal to the building ridge. In addition, it was concluded that the cornering wind mismatch in the roof corner/edge regions could not be solely attributed to the wind-azimuth-independent discrepancy between the turbulence intensity of the approach field and laboratory flows.

Secret Key Generation Using Reciprocity in Ultra-wideband Outdoor Wireless Channels

  • Huang, Jing Jing;Jiang, Ting
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.8 no.2
    • /
    • pp.524-539
    • /
    • 2014
  • To investigate schemes of secret key generation from Ultra-wideband (UWB) channel, we study a statistical characterization of UWB outdoor channel for a campus playground scenario based on extensive measurements. Moreover, an efficient secret key generation mechanism exploiting multipath relative delay is developed, and verification of this algorithm is conducted in UWB Line-of-sight (LOS) outdoor channels. For the first time, we compare key-mismatch probability of UWB indoor and outdoor environments. Simulation results demonstrate that the number of multipath proportionally affects key generation rate and key-mismatch probability. In comparison to the conventional method using received signal strength (RSS) as a common random source, our mechanism achieves better performance in terms of common secret bit generation. Simultaneously, security analysis indicates that the proposed scheme can still guarantee security even in the sparse outdoor physical environment free of many reflectors.

STT-MRAM Read-circuit with Improved Offset Cancellation

  • Lee, Dong-Gi;Park, Sang-Gyu
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • v.17 no.3
    • /
    • pp.347-353
    • /
    • 2017
  • We present a STT-MRAM read-circuit which mitigates the performance degradation caused by offsets from device mismatches. In the circuit, a single current source supplies read-current to both the data and the reference cells sequentially eliminating potential mismatches. Furthermore, an offset-free pre-amplification using a capacitor storing the mismatch information is employed to lessen the effect of the comparator offset. The proposed circuit was implemented using a 130-nm CMOS technology and Monte Carlo simulations of the circuit demonstrate its effectiveness in suppressing the effect of device mismatch.