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Functional outcome predictors following mandibular reconstruction with osteocutaneous fibula free flaps: correlating early postoperative videofluoroscopic swallow studies with long-term clinical results

  • Gonzalez, Santiago R.;Hobbs, Bradley;Vural, Emre;Moreno, Mauricio A.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.30.1-30.8
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    • 2019
  • Background: Advancements in the field of microvascular surgery and the widespread adoption of microvascular surgical techniques have made the use of osteocutaneous fibula free flaps the standard of care in the surgical management of segmental mandibular defects. Although the literature possesses abundant evidence to support the effectiveness of fibula free flaps as a reconstructive method, there are relatively few studies reporting on outcomes as objectively measured by videofluoroscopic swallowing studies (VFSS). The purpose of this study is to explore the potential correlation between early postoperative VFSS and the long-term swallowing outcomes in patients who underwent mandibular reconstruction with fibula free flaps. Methods: We performed a retrospective chart review of 36 patients who underwent mandibular reconstruction with osteocutaneous fibular free flaps between 2009 and 2012. Demographics, clinical variables, VFSS data, and diet information were retrieved. Penetration and aspiration findings on VFSS, long-term oral feeding ability, and the need for gastrostomy tube were statistical endpoints correlated with postoperative clinical outcomes. Results: Thirty-six patients were reviewed (15 females and 21 males) with a mean age of 54 years (7-81). Seventeen cases were treated for malignancy. The size of the bony defect ranged from 3 to 15 cm (mean = 9 cm). The cutaneous paddle, a surrogate for soft tissue defect, ranged from 10 to 125 ㎠ (mean = 52 ㎠). A gastrostomy tube was present in patients preoperatively (n = 8), and postoperatively (n = 14). Seventeen patients had neoadjuvant exposure to radiation. Postoperative VFSS showed penetration in 13 cases (36%) and aspiration in seven (19%). Overall, 29 patients (80.6%) achieved unrestricted diet, and this was statistically correlated with age (p = 0.037), radiation therapy (p = 0.002), and preoperative gastrostomy tube (p = 0.03). The presence of penetration or aspiration on VFSS was a strong predictor for long-term unrestricted oral diet (p < 0.001). Conclusion: Early postoperative VFSS is an excellent predictor for long-term swallowing outcomes in patients undergoing mandibular reconstruction with osteocutaneous fibula free flaps.

Development of Estimation Method for Velocity Pressure Exposure Coefficient of Buildings Based on Spatial Information (공간정보기반 건축물의 풍속고도분포계수 산정 방법 개발)

  • SEO, Eun-Su;CHOI, Se-Hyu
    • Journal of the Korean Association of Geographic Information Studies
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    • v.20 no.2
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    • pp.32-46
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    • 2017
  • Recent rapid urban expansion and crowding of various industrial facilities has affected the features of a significant part of downtown area, resulting in areas having buildings with a wide range of height and the foothills. To compute a velocity pressure exposure coefficient, namely the design wind speed factor, this study defines ground surface roughness by utilizing concentration analysis for the height of each building. After obtaining spatial data by extracting a building layer from digital maps, the study area was partitioned for the concentration analysis and to allow investigation of the frequency distribution of building heights. Concentration analysis by building height was determined with the Variation-to-Means Ratio (VMR) and Poisson distribution analysis using a buildings distribution chart, with statistical significance determined using Chi-square verification. Applying geographic information systems (GIS) with the architectural information made it possible to estimate a velocity pressure exposure coefficient factor more quantitatively and objectively, by including geographic features, as compared to current methods. Thus, this method is expected to eliminate inaccuracies that arise when building designers calculate the velocity pressure exposure coefficient in subjective way, and to help increase the wind resistance of buildings in a more logical and cost-effective way.

Outcomes of Arthroscopic Assisted Reduction and Percutaneous Fixation for Tongue-Type Sanders Type II Calcaneal Fractures (설상형 Sanders 제 II형 종골 골절에 대한 관절경하의 정복 및 경피적 고정술의 결과)

  • Park, Jae Woo;Park, Chul Hyun
    • Journal of Korean Foot and Ankle Society
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    • v.21 no.4
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    • pp.144-150
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    • 2017
  • Purpose: To assess the clinical and radiographic results and complications of arthroscopy-assisted reduction and percutaneous fixation for patients with tongue-type Sanders type II calcaneal fractures. Materials and Methods: Between August 2014 and December 2015, 10 patients who underwent surgery using subtalar arthroscopic assisted reduction and percutaneous fixation for tongue-type Sanders type II calcaneal fractures were reviewed. The mean age was 50.8 years (36~62 years), and the mean follow-up period was 24 months (12~40 months). The clinical results were evaluated using the visual analogue scale (VAS) and American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot score at the regular follow-ups, and the foot function index (FFI) at the last follow-up. The subtalar range of motion (ROM) was evaluated and compared with the uninjured limb at the last follow-up. The radiographic results were assessed using the Bohler's angle from the plain radiographs and the reduction of the posterior calcaneal facet using computed tomography (CT). The postoperative complications were assessed by a chart review. Results: The VAS and AOFAS ankle-hindfoot score improved until 12 months after surgery. The FFI was 15 (1.8~25.9) and subtalar ROM was 75.5% (60%~100%) compared to the uninjured limb at the last follow-up. The $B{\ddot{o}}hler^{\prime}s$ angle was increased significantly from $2^{\circ}$ ($-14^{\circ}{\sim}18^{\circ}$) preoperatively to $21.8^{\circ}$ ($20^{\circ}{\sim}28^{\circ}$) at the last follow-up. The reduction of the posterior facet was graded as excellent in five feet (50.0%) and good in five (50.0%) on CT obtained at 12 months after surgery. One foot (10.0%) had subfibular pain due to a prominent screw head. One foot (10.0%) had pain due to a longitudinal tear of the peroneal tendon that occurred during screw insertion. Conclusion: Subtalar arthroscopic-assisted reduction of the posterior calcaneal facet of the subtalar joint and percutaneous fixation is a useful surgical method for tongue-type Sanders type II calcaneal fractures.

The Retrospective Analysis of 1,162 Traffic Accident Inpatients in Korean Medicine Hospital (교통사고로 한방병원에 입원한 환자 1,162명에 대한 후향적 분석)

  • Shin, Jae-Hwa;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.4
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    • pp.233-250
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    • 2013
  • Objectives The purpose of this study was to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to traffic accident. Methods 1,162 traffic accident patients who were admitted to department of Korean Rehabilitation Medicine of Cheonan Korean Medicine Hospital, Dae-Jeon University from 1st, January, 2011 to 31th, December, 2012 were analyzed according to the medical charts. Results 1. The average treatment result was 3.22 and in most (71.52%) of the patients, symptoms were more than improved. 2. In distribution according to age and sex, people in their 30s numbered the most both in male (12.65%) and female (14.72%). The 1,162 inpatients comprised of 457 (39.33%) male and 705 (60.67%) female. 3. 541 (46.56%) patients admitted in 2011 and 621 (53.44%) patients admitted in 2012. 4. 695 (59.81%) patients visited Cheonan Korean Medicine Hospital within 0~2 days after their traffic accident, followed by 242 (20.83%) patients who visited within 3~5 days after their traffic accident. Patients who admitted earlier showed more improvement in symptoms. 5. The average admission days were 9.32 days. Most (57.66%) patients discharged within 1 week. 6. 825 (71.00%) patients were driving sedan at the time of accident, followed by 105 (9.04%) SUV owners and 71 (6.11%) pedestrians. 7. Rear-end collision accident numbered the most (45.61%), followed by lateral collision (24.35%) and frontal collision (14.72%). 8. Most frequently prescribed examination was X-ray (95.52%), followed by CT (8.69%) and MRI (3.01%). 9. Most frequently given diagnosis was sprain (1,126 (96.90%) patients), followed by concussion & abrasion (178 (15.32%) patients) and fracture (109 (9.38%) patients). 10. Most frequently given Korean medicine treatment was acupuncture (1,162 (100%) patients), followed by anti-inflammatory pharmacopuncture (652 (56.11%) patients) and moxibustion (462 (39.76%) patients). 11. Most frequently given Korean medicine physiotherapy was infra-red (1,161 (99.91%) patients), followed by cupping therapy (1,152 (99.14%) patients) and hotpack (1,137 (97.85%) patients). 12. Most frequently prescribed herb medicine was huishou-san (13.51%), followed by dangguixu-san (12.65%) and yaojiao-tang G (7.06%) Conclusions In this study, people in their 30s, females, within 0~2 days since the accident took the highest percentage from each category of patients who admitted to Korean Medicine Hospital due to traffic accident. Patients who admitted earlier showed more improvement in symptoms and also discharged earlier.

A Statstical Analysis of the Question Categories concerning 'Sasang Constitutional Characteristics of Mind' (성격 특성에 관한 체질판별 문진항목의 통계적 분석)

  • Kim, Hong-Gie;Kim, Jong-Yeol
    • Journal of Sasang Constitutional Medicine
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    • v.15 no.3
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    • pp.124-138
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    • 2003
  • Objectives : To evaluate the properness and effectiveness of the question categories concerning 'sasang constitutional characteristics of mind', used in Iksan Wonkwang Oriental Medicine. Methods : We statistically analyzed data from those 1335 patients focussing on 'relative discrimination ability' to sasang constructions and 'response ratio'. Patients included in this research are only those who had been well treated in Iksan Wonkwang Oriental Medicine during the Period of three years from 2000 to 2002. The data are obtained through the electronic chart developed by Kim Jong-Yeal, and analyzed using the statistical Package SPSS. Results: In total characteristics of mind, the question category of 'timid' has high discriminating power and effectiveness to Soeum type, more in women than men, and especially with an age of 21 or more; The category of 'hasty-tempered' to Soyang type in women with all ages and men with ages 21-40; The category of 'broad-minded' to Taeum type with ages 41 or more; The category of 'timid and broad-minded' to Soyang type, and especially high to women with ages 41 or more. Question categories concerning response type in anger were estimated to have different response patterns to sasang constructions only for ages 21 or more by $X^2$2 test. The question category of 'bear and last long' has high discriminating power and effectiveness to Soeum type, more in men than women, and increasingly to ages; The category of 'impatient and disarmed quickly' to Soyang type in both women and men, especially with ages 21 or more; The category of 'impatient' to Soyang type women or with ages 21 or more. Other categories have low discriminating power or low effectiveness. Concernig expression type of one's thought, the question category of 'straightly' has high discriminating power and effectiveness to Soyang type, more in wemen than men, and especially to ages 21 or more; The category of 'tender' to Soeum type, in women or with ages 40 or less; The category of 'indirectly' to Taeum type in men or with ages 41 or more; The category of 'straightly and stuborn' to Soyang type with ages 41 or more; The category of 'indirectly and tender' to Soeum with with ages 20 or less; The category of 'not express and tender' to Soeum type with ages 41 or more; Conclusions : Question categories concerning total characteristics of mind, response type in anger and expression type of one's thought, are partially discriminating and effective to specific constitution according to sex and ages, and some categories are more discriminating and effective when they are composited. But generally, the discriminating power of Taeum constitution group and group with ages 20 or less was too low, so it is necessary to develope question categories for those groups.

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The Effects of Interrelationship after Wearing between Respirators and Glasses Simultaneously (안면부 여과식 방진 마스크와 안경 동시 착용 시 상호 영향)

  • Eoh, Won Souk;Shin, Chang Sub
    • Journal of the Korean Society of Safety
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    • v.33 no.1
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    • pp.47-53
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    • 2018
  • This study compares the interrelation of fit factor(FF) and visual acuity test by the order of wearing preference between Particulate filtering face piece respirators(PFFR) and glasses for 54 participants. Glasses fitting factors is Optical Center Height(OH), Vertex Distance(VD) and Pantoscopic Angle(PA) or Visual acuity. We measured those factors and expressed by the ratio of standard point and change point. Quantitative fit factor was measured by Portacount Pro+ 8038 and compared the result of preference of wearing order between respirators and glasses. Also, we selected to 6 exercises among 8 exercises OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The pass/ fail criterion of FF was set at 100. Visual acuity test chart is developed by Chunsuk Han was used, Descriptive statistics was performed. Descriptive statistics(SAS ver 9.2), it is used geometric means, Wilcoxon analysis, peason correlation(P=0.05) Fit factor was increased when the respirator was worn before wearing the glasses(p=0.000) and decreased for visual acuity(p=0.000) The negative correlation was showed between OH and Overall fit factor(r=-0.409, p=0.002). Among 54 participants, 11 participants(20.3%) were worn respirator before wearing glasses and 1 participant(1.9%) was worn glasses before wearing respirator. The overall fit test showed the higher level was investigated for the group of participants wearing respirator before wearing glasses in 6 exercises. Also, overall fit factor were increased when participants wore glasses prior to respirator(16.6) to respirator prior to glasses(36.6). Visual acuity were increased when participants wore respirator prior to glasses(93.8) to glasses prior to respirator(106.0). Finally, comparison result of overall fit factor and visual acuity were glasses first choice from mask first choice. The results showed that higher overall fit factor was investigate when the participants wore the respirator prior to glassess at all. The results implied that it is important to maintain the overall fit factor and visual acuity according to the consideration of OH for glasses fitting when worker wore respirator and glasses at the same time.

Design Method for Cast-in-place Energy Pile Considering Equivalent Heat Exchange Rate (등가열교환율을 적용한 현장타설 에너지파일 설계법)

  • Min, Sunhong;Park, Sangwoo;Jung, Kyoungsik;Choi, Hangseok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.3
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    • pp.1049-1061
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    • 2013
  • In this paper, a relative heat exchange rate is numerically compared for cast-in-place concrete energy piles with different heat exchange pipe configurations, and a new design method for energy piles is proposed. An equivalent heat exchange rate was estimated for the W-type (one series loop), multiple U-type (four parallel loops), and coil-type heat exchanger installed in the same large-diameter drilled shaft. In order to simulate a cooling operation in summer by a CFD analysis, the LWT (leaving water temperature) into a energy pile was fixed at $35^{\circ}C$ and then the EWT (entering water temperature) into a heat pump was monitored. In case of continuously applying the artificial maximum cooling load for 100 hours, all of the three types of heat exchangers show the marginally similar heat exchange rate. However, in case of intermittently applying the cooling load with a cycle of 8 hours operation-16 hours off for 7 consecutive days, the coil type heat exchanger exhibits a heat exchange rate only 86 % of the multiple U-type due to measurable thermal interference between pipe loops in the energy pile. On the other hand, the W-type possesses the similar heat exchange rate to the multiple U-type. The equivalent heat exchange rates for each configuration of heat exchangers obtained from the CFD analysis were adopted for implementing the commercial design program (PILESIM2). Finally, a design method for cast-in-place concrete energy piles is proposed along with a design chart in consideration of typical design factors.

A Study of STEAM Education for Elementary Science Subject with Robots (교육용 로봇을 활용한 초등학교 과학교과의 STEAM교육 수업 방안)

  • Hong, Ki-Cheon;Shim, Jae-Kuk
    • Journal of The Korean Association of Information Education
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    • v.17 no.1
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    • pp.83-91
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    • 2013
  • The Ministry of Education issues STEAM education as a part of convergence. Most important is "How to achieve goals of STEAM education". The goal of this paper searches possibilities that robot is a good tool for STEAM education. The main topic is photosynthesis unit as circumstantiation and "Deep sea exploration robot", is creative activity, in elementary science subject. Students complete 13 basic course about robot, then accomplish subject-oriented 10 robot application course about above topic. Basic course contains math and science elements that students learn in regular curriculum. Application course is organized following steps, photosynthesis with oxygen sensors, brainstorming, idea derivation, robot design, robot construction, demo and presentation and so on. These courses have elements of STEAM. Finally teacher has face-to-face meeting with parents and students. Most have positive aspects about this process in terms of creativity, study attitude, and school life. Specially low-ranking students win a prize in robot competition. So they can gain confidence and accomplishment. This paper don't show statistic chart, but we surely knew that robot education for STEAM education seriously affect creativity huminity and job search.

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Seroepidemiologic Evidence for the Presence of Hantavirus in South Africa (남아프라카 지역내 한타바이러스 존재에 관한 혈청 역학적 증거)

  • Lee, Pyung-Woo;Park, Man-Seong;Keen, G.Anthony;Noveljic, Z.;Tucker, Tim J.;Ryst, Elna van der;Viljoen, Johannes I.;Pretorius, Anne-Marie;Oelofsen, Mike
    • The Journal of Korean Society of Virology
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    • v.29 no.1
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    • pp.11-22
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    • 1999
  • Sero-epidemiologic survey has been carried out to establish serologically the presence of hantavirus in areas of South Africa. The survey was oriented to search natural infection in both of humans and wild rodents and involvement of human disease. The normal human sera were collected from the residents in urban and rural areas of Western Cape, and rural area of Eastern Cape province. The rodent sera came from various species of rodents trapped in Northern Cape and Western Free provinces. The patient sera were selected from the patients of renal failure, pulmonary syndrome and pyrexia of unknown origin (PUQ) according to diagnostic chart among the patients hospitalized in major hospitals of Cape Town area. The sera were screened and titrated by IFA test using antigens of Hantaan (HTN), Seoul (SEO), Puumala (PUU), and Prospect Hill (PH) viruses primarily. Positive cases were subjected to differential IFA test using HTN, PUU and PH antigens and plaque reduction neutralization test for further confirmation. Anti-hantavirus antibodies were detected from 2 of 352 rural, 1 of 172 urban residents of E. Cape, and 5 of 118 rural, 5 of 368 urban residents of W. Cape. The antibody was also demonstrated from 5 of 221 wild rodents, and it was appeared that 2 different species, Aethomys namaquensis and Tatem leucogaster, are involved. Among 318 patients tested, 3 who were diagnosed as chronic renal failure, acute respiratory distress syndrome (ARDS) and glomerulonephritis were proved to be positive. The reaction patterns obtained from all of these positive sera were distinct from hantaviral sero-patterns ever established. This result suggests that new viruses may exist in this area and play an possible etiologic role in human disease. The feature of serologic survey on anti-hantavirus antibody demonstrable newly from African wild rodents which are different from reservoir species in other continents elicits a conjecture that the virus may be different from known hantaviruses ever found. This fact also suggests that an expanded role in etiologic involvement with other unknown human diseases by newly emerging hantaviruses may be possible in this areas.

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Association between Maternal and Cord Blood Interleukin-10 (-819T/C and -592A/C) Gene Polymorphisms and Respiratory Distress Syndrome in Preterm Korean Infants (한국 미숙아 산모와 제대혈의 IL-10 유전자형 빈도와 신생아 호흡 곤란증 발생과의 연관성)

  • Park Eun-Ae;Cho Su-Jin;Kim Young-Ju;Park Hye-Sook;Ha Eun-Hee;Suh Young-Ju
    • Neonatal Medicine
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    • v.16 no.2
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    • pp.137-145
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    • 2009
  • Purpose: The aim of this study was to determine the genotype frequencies of interleukin 10 (IL-10) gene polymorphisms and to investigate their association with the risk of respiratory distress syndrome (RDS) in preterm Korean infants. Methods: Two hundred fourteen preterm infants born at Ewha Womans University Mok Dong Hospital between November 2003 and July 2008 were studied. The cord blood of preterm neonates and the corresponding maternal blood were analyzed by PCR for IL-10 gene (IL-10 -1082A/G, -819T/C, and -592A/C) polymorphisms. The clinical data of patients were collected retrospectively by chart review. Results: The genotype frequencies of IL-10 genes in Korean mothers with preterm infants differ from other reports. The prevalence of two promoter SNPs of the IL-10 cytokine gene was similar but none had the IL-10-1082GG homozygote. Multiple logistic regression analysis demonstrated the risk of RDS to be significantly lower in the infants of the mothers with an IL-10-592AC/CC genotype than in those with an AA genotype (P=0.033). The risk of RDS was significantly lower in the mother with an IL-10-819TC/CC genotype than in those with a TT genotype (P=0.030). However, IL-10 polymorphisms in the cord blood were not significantly different in preterm infants with RDS compared with the preterm infants without RDS. When we compared the incidence of RDS and each IL-10A-1082G/T-819C/A-592C haplotype, the ACC haplotype had a protective effect on RDS (P=0.007). Conclusion: We conclude that the maternal IL-10-592A/C and IL-10-819T/C polymorphisms may have a role in the development of the RDS in preterm infants.