• 대한토목학회논문집
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• 제33권3호
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• pp.947-956
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• 2013

본 연구에서는 낙동강-금호강 합류부의 생태유량을 산정하기 위해 2차원 수치모형 River2D를 이용하여 가중가용면적(WUA, Weighted Usable Area)을 계산했다. River2D 모형의 검증을 위해 HEC-RAS모의결과와 비교하여 최적 매개변수를 결정했다. 그리고 낙동강의 우점종인 피라미와 갈겨니를 대상으로 낙동강과 금호강의 유량을 변화시키며 가중가용면적을 모의했다. 유량-WUA/A의 그래프로부터 생태유량을 산정한 결과, 낙동강의 경우 $33.3m^3/s{\sim}40.0m^3/s$, 금호강의 경우 $3.60m^3/s{\sim}4.32m^3/s$를 낙동강-금호강 합류부의 생태유량으로 결정하였다. 결정된 생태유량을 적용하여 낙동강 본류의 하상준설 이후 피라미와 갈겨니의 가중가용면적을 계산한 결과, 가중가용면적이 약 1/9로 감소했다. 그리고 준설 이후에 잉어에 대한 가중가용면적은 피라미와 갈겨니에 대한 것보다 2~3배 더 큰 것으로 계산됐다.

• 한국수자원학회논문집
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• 제40권3호
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• pp.265-276
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• 2007

홍수터에 식생된 하도에서 수리학적 특성의 이해는 하천복원사업을 계획하거나 홍수터를 관리하는데 중요하다. 본 연구에서는 길이 16 m，폭 0.8 m 의 실험수로에 인공식생을 이용하여 수리학적 특성변화를 분석하였다. 실험수로 단면은 단단면과 복단면으로 구분하였다. 하상경사는 0.5 %，유량은 $0.2\;m^3/s\;{\sim}\;0.4\;m^3/s$ 범위이고，수심비，식생밀도, 식생 위치를 변화시키면서 실험을 수행하였다. 단단면 수로 저면에 식생하였을 경우 수심비가 약，3.5 이상부터는 식생에 의한 수위 증가는 거의 없는 것으로 관측되었다. 복단면 홍수터에 관목을 식생 할 경우 수위 상승량은 최대 6% 정도이며，저수로 내 유속은 식생전의 단면평균유속에 비하여 약 25% ${\sim}$ 85% 정도로 증가하였다. 홍수터 식생에 의한 저수로 유속 증가량은 식생밀도와 비례하고 수심비와는 반비례한다. HEC -RAS 및 RMA-2 모형을 이용하여 산정된 식생 구간의 조도계수 범위는 단단면의 경우 0.055 ${\sim}$ 0.14 이며， 복단면에서는 0.063 ${\sim}$ 0.085 정도로 산정되었다.

• 전자공학회논문지SC
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• 제42권1호
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• pp.39-45
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• 2005

본 논문은 밀리미터파를 이용한 무혈혈당측정기 개발의 기초연구로서, 높은 유전손실을 지닌 유전체의 반사 유전특성 측정법을 제시하고, 이에 의해 10～90 GHz의 밀리미터파 대역에서 글루코오스 농도에 따른 글루코오스 수용액 및 글루코오스 -0.9% NaCl 용액의 유전특성 변화를 조사하였다. 제시된 측정법은 측정 유전제의 앞단에 평행평면판을 배치하여 측정 주파수대역 내에서 전력반사계수가 최소가 되는 최소반사조건이 형성되도록 하고, 이 조건에서 측정된 최소 전력반사계수와 주파수로부터 측정 유전체의 유전특성을 결정할 수 있는 방법이다. 순수의 유전특성에 대한 측정 결과들은 제시된 측정법의 타당성을 입증하였다. 또한 10～90 GHz 대역에서 글루코오스 농도 변화에 따른 글루코오스 용액 및 글루코오스 -0.9% NaCl 용액들의 유전특성 변화에 대한 실험을 통해, 타 대역에 비해 30～45 GHz 범위에서 글루코오스 농도 변화에 의한 각 용액들의 유전특성의 변화가 최대임을 알 수 있었다. 이를 통해 본 측정법에서 전력반사계수와 주파수의 측정 정밀도가 각각 ±0.1 dB와 ±0.01 GHz일 경우, 대략 3 mole/L 정도의 분해능으로 용액 내 글루코오스 농도 변화를 측정할 수 있음을 보였다.

• 대한약침학회지
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• 제9권2호
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• pp.17-37
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• 2006

Objectives : To observe the changes in the serum proteins after intravenous injection of cultivated wild ginseng pharmacopuncture. Methods : Blood was collected before and after the administration of cultivated wild ginseng pharmacopuncture and only the serum was taken. Then differences in the spots on the scanned image after carrying out 2-Dimensional electrophoresis were located and conducted mass analysis and protein identification. Results : Following results were obtained from the comparative analysis of serum proteins before and after the administration of cultivated wild ginseng pharmacopuncture. 1. 28 spots were identified before and after the administration. 2. In confirming manifestation degree, spots with more than two-times increase were 204, 1302, 2205, 3105, 7104, 8006, spots with more than one-time increase were 1101, 1505, 2013, 2403, 3009, 3010, 4002, 4009, 6704, 8101, and spots with decrease were 205, 801, 803, 3205, 5202, 6105, 6106, 7103, 9001, 9003. 3. After conducting protein identification, proteins 205, 804, 1302, 4009, 6105, 6106 are unidentified yet, and 1l01 is unnamed protein. Protein 204 is identified as complement receptor CR2-C3d, 801 as YAPl protein, 803 as antitrypsin polymer, 1505 as PRO0684, 2013 and 3010 as proapolipoprotein, 2205 as USP48, 2403 as vitamin D binding protein, 3009 as complement component 4A preprotein, 3105 as immunoglobulin lambda chain, 3205 as transthyretin, 4002 as Ras-related protein Ral-A, 4204 as beta actin, 5202 and 7104 as apolipoprotein Ll, 6704 as alpha 2 macroglobulin precursor, 7103 as complement component 3 precursor, 8006 as testis-specific protein Y, 8101 as transferrin, 9001 as (Alpha-Oxy, Beta-(Cl12g)deoxy) T-State Human Hemoglobin, and 9003 as human hemoglobin. 4. Immune protein CR2-C3d(204), which acts against microbes and pathogenic organisms, was increased by more than two-times after the administration of pharmacopuncture. 5. Antitrypsin(803), which is secreted with inflammatory response in the lungs, was reduced after the administration of pharmacopuncture. 6. Proapolipoprotein(2013, 3010) and apolipoprotein(7104), key components of the HDL-cholesterol which plays an important role in preventing arteriosclerosis, were increased after the administration of pharmacopuncture. 7. Vitamin D binding protein(DBP, 2403), protecting the lung at the time of inflammatory response, was increased after the administration of pharmacopuncture. 8. Transthyretin(TTR, 3205), which is the main protein causing familial amyloid polyneuropathy(FAP), was decreased after the administration of pharmacopuncture. 9. Ras-related protein Ral-A(4002) that controls phospholipid metabolism, cytoskeletal formation, and membrane traffic, was increased after the administration of pharmacopuncture. 10. Testis-specific protein Y(8006), which takes part in determination of the gender, was increased by more than two-times after the administration of pharmacopuncture. 11. Transferrin(8101), which balances the iron level in the body, was increased after the administration of pharmacopuncture. Conclusion : Above results support the notion that intravenous injection of cultivated wild ginseng pharmacopuncture induce changes in serum proteins and this research can be a pioneer work in finding biomarkers.

• 한국환경복원기술학회지
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• 제10권1호
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• pp.23-35
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• 2007

Nowadays, as a result of increasing income and spare time, the social demands for better living environment become more increasing. Above all, landscape improvement, the essential part of physical environment, will be a more important subject in urban planning. In these circumstances, classification of urban scenic quality is required for urban landscape development programs. The major purpose of this study is to suggest a technical method of designing urban scenic quality map for urban district area based on the scenery management system of the USDA forest service and literature studies. As a conclusion of this study, four steps are desirable for the technical method for designing a scenic quality map of urban districts areas : 1) Define a landscape unit on the map, 2) Take a photograph of these landscape unit on site, 3) Evaluate the landscape unit by semantic differential scale with landscape adjectives, and 4) Draw the scenic quality map, investigate the landscape characteristics and suggest the landscape scenic development plans.

• Neonatal Medicine
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• 제18권2호
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• pp.374-378
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• 2011

누난 증후군은 전형적인 얼굴 모양, 선천성 심질환, 저신장을 특징으로 하는 우성유전 질환으로 출생시부터 임상증상으로 진단하는데 어려움이 있다. 이에 최근 RAS-MAPK 경로 변이로 확진되는 경우가 많고, 유전 변이 유형에 따른 임상 증상이 차이가 나는 경우도 많다. 유전 변이 확진으로 말미암아 임상 증상에 대한 적극적인 치료와 경과 관찰이 중요하므로 저자들은 국내에서 드문 KRAS 유전 변이 환아를 출생시부터 임상증상으로 진단하고 확진한 경험을 하여 이를 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제45권3호
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• pp.604-608
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• 1998

Von Recklinghausen병에 동반되는 악성종양은 주로 신경섬유육종이지만 드물게는 폐암이 동반되는 경우가 보고되고 있고 ras 유전자가 양 질환의 발생에 영향이 있음이 알려져 있어 앞으로 이에 관한 연구가 필요하리라 생각된다.

• Environmental Analysis Health and Toxicology
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• 제20권4호통권51호
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• pp.303-309
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• 2005

Essential hypertension has been considered as multifactorial disease resulted from the interaction of both environmental and genetic factors. The renin-angiotensin system (RAS) plays an important role in the regulation of blood pressure homeostasis. Recently, a homologue of angiotensin I converting enzyme, ACE2 has been focused on as a candidate gene of essential hypertension in the experiments using animal model and human being. In this study, we carried out an association study in order to clarify the relationship between the A 1075G polymorphism in the ACE2 gene and essential hypertension in Korean subjects. Because this polymorphism is located on human chromosome X, the statistical analysis for each gender was performed separately. There were no significant differences in allele distribution of the A 1075G polymorphism in the ACE2 gene between normotensives and hypertensives in the both gender groups, respectively. However, this polymorphism was significantly associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) values in only female groups (P< 0.05). Thus, these results may suggest the probable role of ACE2 gene in the inter-individual susceptibility of female group to blood pressure variability.

• 한국수산과학회지
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• 제46권6호
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• pp.675-681
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• 2013

There have been many studies on biofilter process regarding satisfactory water quality and the operational conditions of Recirculating Aquaculture Systems (RAS). For effective nitrification processes, it is necessary to dynamically identify and apply nitrifying microorganisms. Physical, chemical and biological processes concerning biofilms can be applied and influential factors including substrate, dissolved oxygen concentrations, organic matter, temperature, pH, alkalinity, salinity and mixing velocity intensity need to be considered. Also, designing and managing the process based on the dynamic interpretation of these factors are prerequisites for engineering applications of the biofilter process. This paper draws on current literature on the kinetics of nitrification of biofilms in the biofilter process. Influential factors for nitrification are crucial during the biofilter process and are expected to be critical in informing the design and operation of recirculating aquaculture systems.

• 한국조경학회지
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• 제33권4호
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• pp.1-10
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• 2005

Recently, as urban landscape is growing in importance, urban landscape planning is being actively performed. for this purpose, classification of the urban landscape is definitely required. Therefore, this research focuses on classifying urban landscape in Daejeon metropolis by dividing the urban land use pattern. This results are as follows. 1. Urban land use pattern is divided into 20 classes. The residential, commercial and industrial areas, the old market and the bus terminal are evaluated negatively, whereas the areas of school, water reservoir, neighborhood park and train station are appreciated as being positive in landscape characters. 2. As a result of a cluster analysis, urban landscape has five different landscape types. These are: landscapes of medium diversity lacking green area, landscapes of high diversity lacking green area, landscapes rich in green area and with medium diversity, landscapes rich in green area and with high diversity, and landscapes rich in green area and with low diversity. 3. In landscape characters of beauty and harmony, landscapes rich in green area and with medium diversity are more positively evaluated than those rich in green area and with low diversity. This point should be taken into account for planning the urban landscape.