• Title/Summary/Keyword: K-Ras

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Determination of Ecological Flow at the Confluence of Nakdong River and Gumho River Using River2D (River2D를 이용한 낙동강-금호강 합류부의 생태유량 산정)

  • Seo, Il Won;Park, Inhwan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.3
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    • pp.947-956
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    • 2013
  • In this study, WUA (Weighted Usable Area) was calculated to determine ecological flow at the confluence of Nakdong River and Gumho River by using River2D. To calibrate River2D, simulation results of River2D were compared with calibrated HEC-RAS simulation results and the optimum parameters were determined. After parameter calibration, WUA of Zacco platypus and Zacco temmincki which are dominant species in Nakdong River was calculated with changing upstream flowrate. From the result, WUA is changed according to flowrate and growth stage. In the flowrate-WUA/A graph, ecological flow can be determined as $33.3m^3/s{\sim}39.96m^3/s$ in Nakdong River and $3.6m^3/s{\sim}4.32m^3/s$ in Gumho River. After dredging for Four major rivers restoration project, WUA of Zacco platypus and Zacco temmincki were calculated by using the ecological flow. The results show that WUA after dredging are decreased when compared with undredged condition. WUA of Common carp is 2~3 times bigger than WUA of Zacco platypus and Zacco temmincki at the dredged condition in Nakdong River.

An Experimental Study on the Variation of Hydraulic Characteristics due to Vegetation in Open Channel (개수로에서 식생에 의한 수리특성 변화에 관한 실험적 연구)

  • Lee, Joon-Ho;Yoon, Sei-Eui
    • Journal of Korea Water Resources Association
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    • v.40 no.3
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    • pp.265-276
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    • 2007
  • An understanding of the hydraulic characteristics in the compound channel with vegetation is important in designing stream restorations or managing the floodplain. A laboratory flume of 16 m long and 0.8 m wide was used for analysis of the hydraulic characteristics in the single section channel and the compound channel with artificial vegetation. Slope of experimental channel is 0.5 %. Discharges are ranged from $0.2\;m^3/s\;to\;$0.4\;m^3/s$. The experiments were done by changing water depth ratio, vegetation density and vegetation location. When water depth ratio in the single section channel with vegetation increase up to 3.5, the results showed that the increment of water depth due to vegetation may be ignored in practice. The maximum increment of water depth was measured up to 6 % in the compound channel with vegetation and the range of velocities increment in the low flow channel was from 25 % to 85 % compared with section average velocities. As the vegetation densities increase and water depth ratios decrease, the velocity of the low flow channel increased. The range of roughness coefficients in the vegetated reaches were estimated from 0.055 to 0.14 in the single section channel and from 0.063 to 0.085 in the compound channel using HEC-RAS and RMA-2 model.

Basic Investigation for the Won-invasive Measurement of Blood Glucose Concentrations by Millimeter Waves (밀리미터파를 이용한 무혈 혈당 측정에 관한 기초 연구)

  • Kim Dong Kyun;Won Jong Hwa;Potapov Sergey N.;Meriakri Viacheslav V.;Chigryai Evgenii E.
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.42 no.1
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    • pp.39-45
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    • 2005
  • As a basic research for the development of a non-invasive blood glucose sensor using millimeter waves, we have presented a method for measuring the dielectric properties of high loss dielectrics, based on the reflection method, and investigated the variation of the dielectric properties of glucose-water and glucose -0.9% NaCl solutions in the 10~90 GHz range. In the proposed method, a minimal reflection condition is formed by placing a specially-chosen low-loss plane-parallel plate in front of a high-loss medium under test at a given frequency range. Using the minimal power reflection coefficient and the corresponding frequency at this condition, tile dielectric properties of the medium can be determined. The measured results on pure water have shown the adequacy of the proposed method. The measured results on glucose-water and glucose -0.9% NaCl solutions in the 10~90 GHz range showed that the variations of the dielectric properties of glucose solutions according to the change of their glucose concentration were maximum in the 30~45 GHz range. From these facts we concluded that the variation of about 3 mole/L in the glucose solutions must be distinguished With the measurement accuracies of ±0.1 dB and ±0.01 GHz.

Analysis of Serum Proteom after Intravenous Injection of cultivated wild ginseng pharmacopuncture (산양산삼 증류약침의 혈맥주입 후 나타나는 혈장의 Proteom 분석)

  • Lee, Dong-Hee;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.9 no.2
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    • pp.17-37
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    • 2006
  • Objectives : To observe the changes in the serum proteins after intravenous injection of cultivated wild ginseng pharmacopuncture. Methods : Blood was collected before and after the administration of cultivated wild ginseng pharmacopuncture and only the serum was taken. Then differences in the spots on the scanned image after carrying out 2-Dimensional electrophoresis were located and conducted mass analysis and protein identification. Results : Following results were obtained from the comparative analysis of serum proteins before and after the administration of cultivated wild ginseng pharmacopuncture. 1. 28 spots were identified before and after the administration. 2. In confirming manifestation degree, spots with more than two-times increase were 204, 1302, 2205, 3105, 7104, 8006, spots with more than one-time increase were 1101, 1505, 2013, 2403, 3009, 3010, 4002, 4009, 6704, 8101, and spots with decrease were 205, 801, 803, 3205, 5202, 6105, 6106, 7103, 9001, 9003. 3. After conducting protein identification, proteins 205, 804, 1302, 4009, 6105, 6106 are unidentified yet, and 1l01 is unnamed protein. Protein 204 is identified as complement receptor CR2-C3d, 801 as YAPl protein, 803 as antitrypsin polymer, 1505 as PRO0684, 2013 and 3010 as proapolipoprotein, 2205 as USP48, 2403 as vitamin D binding protein, 3009 as complement component 4A preprotein, 3105 as immunoglobulin lambda chain, 3205 as transthyretin, 4002 as Ras-related protein Ral-A, 4204 as beta actin, 5202 and 7104 as apolipoprotein Ll, 6704 as alpha 2 macroglobulin precursor, 7103 as complement component 3 precursor, 8006 as testis-specific protein Y, 8101 as transferrin, 9001 as (Alpha-Oxy, Beta-(Cl12g)deoxy) T-State Human Hemoglobin, and 9003 as human hemoglobin. 4. Immune protein CR2-C3d(204), which acts against microbes and pathogenic organisms, was increased by more than two-times after the administration of pharmacopuncture. 5. Antitrypsin(803), which is secreted with inflammatory response in the lungs, was reduced after the administration of pharmacopuncture. 6. Proapolipoprotein(2013, 3010) and apolipoprotein(7104), key components of the HDL-cholesterol which plays an important role in preventing arteriosclerosis, were increased after the administration of pharmacopuncture. 7. Vitamin D binding protein(DBP, 2403), protecting the lung at the time of inflammatory response, was increased after the administration of pharmacopuncture. 8. Transthyretin(TTR, 3205), which is the main protein causing familial amyloid polyneuropathy(FAP), was decreased after the administration of pharmacopuncture. 9. Ras-related protein Ral-A(4002) that controls phospholipid metabolism, cytoskeletal formation, and membrane traffic, was increased after the administration of pharmacopuncture. 10. Testis-specific protein Y(8006), which takes part in determination of the gender, was increased by more than two-times after the administration of pharmacopuncture. 11. Transferrin(8101), which balances the iron level in the body, was increased after the administration of pharmacopuncture. Conclusion : Above results support the notion that intravenous injection of cultivated wild ginseng pharmacopuncture induce changes in serum proteins and this research can be a pioneer work in finding biomarkers.

A Study on the Technical Method for Urban Scenic Quality Map - Focused on Urban District Area - (도시 경관도 작성 기법 연구 - 시가화 지역을 중심으로 -)

  • Kim, Dae-Hyun;Kim, Dae-Soo;Joo, Shin-Ha;Oh, Se-Rae
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.1
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    • pp.23-35
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    • 2007
  • Nowadays, as a result of increasing income and spare time, the social demands for better living environment become more increasing. Above all, landscape improvement, the essential part of physical environment, will be a more important subject in urban planning. In these circumstances, classification of urban scenic quality is required for urban landscape development programs. The major purpose of this study is to suggest a technical method of designing urban scenic quality map for urban district area based on the scenery management system of the USDA forest service and literature studies. As a conclusion of this study, four steps are desirable for the technical method for designing a scenic quality map of urban districts areas : 1) Define a landscape unit on the map, 2) Take a photograph of these landscape unit on site, 3) Evaluate the landscape unit by semantic differential scale with landscape adjectives, and 4) Draw the scenic quality map, investigate the landscape characteristics and suggest the landscape scenic development plans.

Noonan Syndrome Confirmed to KRAS Gene Mutation: A Case of KRAS Gene Mutation (KRAS 유전자 변이로 확진된 Noonan 증후군 신생아 1례)

  • Kim, Sung-Woo;Park, So-Eun;Jeong, In-Hyuk;Yoon, Jeong-Won;Lee, Cho-Ae;Jeon, Ji-Hyun
    • Neonatal Medicine
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    • v.18 no.2
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    • pp.374-378
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    • 2011
  • Noonan syndrome is an autosomal dominant disorder characterized by typical facial features, congenital heart disease, and short stature. Diagnosis is difficult only with clinical symptoms and it is recently confirmed with gene study. The genotype-phenotype correlations have been reported. We report a newborn with KRAS gene mutation. This is the second report of case with KRAS gene mutation in Korea. So we hope this case will be a help to diagnosis and treatment of Noonan syndrome from birth.

A Case of Lung Cancer associated with von Recklinghausen's Disease (Von Recklinghausen 병에 동반된 폐암 1예)

  • Han, Yo-Seb;Kang, Hong-Mo;Han, Min-Soo;Yoo, Jee-Hong
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.3
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    • pp.604-608
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    • 1998
  • Von Recklinghausen's disease is an autosomal dominant hereditary disease associated with characteristic cafe-au-lait spots of skin and multiple neurofibromatosis. It is complicated by malignancies, which in most cases is neurofibrosarcoma. The development of lung cancer in von Recklinghausen's disease is rare. A 61-year-old male was admitted for cough and sputum for 20 days. He had multiple cafe-au-lait spots and subcutaneous neurofibromas in whole body area and Lisch nodules in both iris and he had been diagnosed von Recklinghausen's disease 35 years ago. Chest radiography showed emphysematous bullae in both upper lung field and mass in right upper lung field. Chest CT scan revealed subcarinal lymph node enlargement. Bronchoscopic biopsy was done in mass in superior segment of right lower lobe and the results showed squamous cell carcinoma. The presence of von Recklinghausen's disease and lung cancer are noteworthy.

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The Distribution of Genetic Polymorphism in the ACE2 Gene in Korean Essential Hypertensives (한국인 본태성 고혈압 환자군에서 ACE2유전자에 존재하는 A1075G다형성의 분포에 관한 연구)

  • Jang Min Hee;Kang Byung Yong;Lee Jae Koo;Lee Kang Oh
    • Environmental Analysis Health and Toxicology
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    • v.20 no.4 s.51
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    • pp.303-309
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    • 2005
  • Essential hypertension has been considered as multifactorial disease resulted from the interaction of both environmental and genetic factors. The renin-angiotensin system (RAS) plays an important role in the regulation of blood pressure homeostasis. Recently, a homologue of angiotensin I converting enzyme, ACE2 has been focused on as a candidate gene of essential hypertension in the experiments using animal model and human being. In this study, we carried out an association study in order to clarify the relationship between the A 1075G polymorphism in the ACE2 gene and essential hypertension in Korean subjects. Because this polymorphism is located on human chromosome X, the statistical analysis for each gender was performed separately. There were no significant differences in allele distribution of the A 1075G polymorphism in the ACE2 gene between normotensives and hypertensives in the both gender groups, respectively. However, this polymorphism was significantly associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) values in only female groups (P< 0.05). Thus, these results may suggest the probable role of ACE2 gene in the inter-individual susceptibility of female group to blood pressure variability.

A Study of Nitrification Kinetics in the Biofilter Process for Aquaculture Water Treatment: A Review (양식 수처리를 위한 생물막 공정에서 질산화 영향인자에 대한 고찰)

  • Park, Noh Back;Park, Mi Seon;Lee, Jin Hwan;Myeong, Jeong In
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.46 no.6
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    • pp.675-681
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    • 2013
  • There have been many studies on biofilter process regarding satisfactory water quality and the operational conditions of Recirculating Aquaculture Systems (RAS). For effective nitrification processes, it is necessary to dynamically identify and apply nitrifying microorganisms. Physical, chemical and biological processes concerning biofilms can be applied and influential factors including substrate, dissolved oxygen concentrations, organic matter, temperature, pH, alkalinity, salinity and mixing velocity intensity need to be considered. Also, designing and managing the process based on the dynamic interpretation of these factors are prerequisites for engineering applications of the biofilter process. This paper draws on current literature on the kinetics of nitrification of biofilms in the biofilter process. Influential factors for nitrification are crucial during the biofilter process and are expected to be critical in informing the design and operation of recirculating aquaculture systems.

The Classification and Characteristics of Landscape on Urban Land Use Patterns - The Case of Metropolitan Daejeon - (도시의 토지이용 형태별 경관특성과 유형 - 대전광역시를 사례로 -)

  • Kim Dae-Hyun;Kim Dae-Soo;Joo Shin-Ha;Oh Se-Rae
    • Journal of the Korean Institute of Landscape Architecture
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    • v.33 no.4 s.111
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    • pp.1-10
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    • 2005
  • Recently, as urban landscape is growing in importance, urban landscape planning is being actively performed. for this purpose, classification of the urban landscape is definitely required. Therefore, this research focuses on classifying urban landscape in Daejeon metropolis by dividing the urban land use pattern. This results are as follows. 1. Urban land use pattern is divided into 20 classes. The residential, commercial and industrial areas, the old market and the bus terminal are evaluated negatively, whereas the areas of school, water reservoir, neighborhood park and train station are appreciated as being positive in landscape characters. 2. As a result of a cluster analysis, urban landscape has five different landscape types. These are: landscapes of medium diversity lacking green area, landscapes of high diversity lacking green area, landscapes rich in green area and with medium diversity, landscapes rich in green area and with high diversity, and landscapes rich in green area and with low diversity. 3. In landscape characters of beauty and harmony, landscapes rich in green area and with medium diversity are more positively evaluated than those rich in green area and with low diversity. This point should be taken into account for planning the urban landscape.