• Proceedings of the Korea Society for Industrial Systems Conference
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• 한국산업정보학회 1998년도 공동추계학술대회 경제위기 극복을 위한 정보기술의 효율적 활용
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• pp.551-562
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• 1998

• The Zoological Society Korea : Newsletter
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• 제12권2호
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• pp.119.2-119
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• 1995

No Abstract, See Full Text

• 정보산업연감
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• 통권1992호
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• pp.553-562
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• 1992

• Bulletin of the Korean Chemical Society
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• 제29권3호
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• pp.562-566
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• 2008

Reaction of AgNO3 with triethanolaminetriisonicotinate (L) produces 1 D coordination polymer of [Ag3(L)2](NO3)3 and the same treatment of Cu(NO3)2 with L gives 1D coordination polymer of [Cu(L)2](NO3)2. The nonrigid triethanolaminetriisonicotinate acts as a m 3-bridged tridentate for [Ag3(L)2](NO3)3 and a m 2-bridged bidentate for [Cu(L)2](NO3)2 to produce unusual motifs. The NO3- anions can be smoothly exchanged by PF6- anions in an aqueous suspension without destruction of the skeletal structure.

• Proceedings of the Korea Information Processing Society Conference
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• 한국정보처리학회 2016년도 춘계학술발표대회
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• pp.562-566
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• 2016

클라우드 컴퓨팅의 발전과 더불어 데이터베이스 아웃소싱에 대한 연구가 활발히 진행되고 있다. 그러나 기존 정보보호를 지원하는 Topk 질의처리 연구는 다양한 형태로 정보가 노출되는 문제점을 보인다. 따라서 본 논문에서는 데이터 보호, 사용자 질의 보호, 데이터 접근 패턴 은닉을 모두 지원하는 아웃소싱 데이터베이스 상에서의 안전한 Topk 질의처리 알고리즘을 제안한다. 성능평가를 통해, 제안하는 기법이 정보보호를 지원하는 동시에 효율적인 성능을 제공함을 보인다.

• Proceedings of the Korea Information Processing Society Conference
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• 한국정보처리학회 2019년도 춘계학술발표대회
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• pp.562-563
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• 2019

본 연구는 한국 프로 야구 선수 개인의 수치화된 데이터를 바탕으로 타석의 결과를 예측하고자 하는데 목적을 두고 있다. 연구의 방법은 2015시즌부터 2018시즌에 활약한 한국 프로 야구 소속의 투수와 타자의 유형을 군집화 하여 지도학습 모델을 만든다. 지도학습 모델과 현재까지 진행된 2019시즌의 결과를 비교·대조한다. 본 연구결과는 한국 프로 야구 10개 구단의 감독의 선수 선발 결정에 기여할 것으로 판단된다.

• Archives of Pharmacal Research
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• 제20권4호
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• pp.342-345
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• 1997

A cytotoxic constituent was isolated by bioassay-guided procedure from the roots of Sophora flavescens Aiton (Leguminosae). The constituent was identified as sophoraflavanone G (I) by means of chemical methods and in comparsion with spectral data of standard compound. The $ED_50$ values of constituent I were 0.78, 1.57, 2.14 and $8.59{\mu}g/ml$ against A549, HeLa, K562 and L1210 cell lines, respectively. Constituent I exhibited highly cytotoxic activities against A549, K562 and HeLa cells, but showed a mild activity $$(ED_50 value, 5{\mu}g/ml)$$ against L1210 cells. Among the tested cell lines, A549 cells were the most sensitive to constituent I.

• Archives of Pharmacal Research
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• 제20권4호
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• pp.368-371
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• 1997

In an effort to increase of the antitumor activity of 2(S)-$2^{I}$,$5^{I}$-trihydroxy-7, 8-dimethoxyflavanone isolated from Scutellaria indica, we synthesized its analogues, II, III and IV. They showed potent cytotoxicity in vitro against cancer cell lines, L1210, K562 and A549. On the basis of $ED_50$ values against the cancer cell lines, III exhibited about 2-7 times stronger activity than I against various cell lines. We tested the antitumor activity of the analogues against Sarcoma 180 cells in vivo and evaluated the structure-activity relationship. The antitumor activity appeared to be related to the hydrogen bond between carbonyl group at C-4 and hydroxyl group at C-5, in contrast to cytotoxic action.

• Journal of Ginseng Research
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• 제22권3호
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• pp.188-192
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• 1998

We established the model of clonogenic assay with human tumor cell line such as Calu-3 (lung carcinoma), HEC- lB (endometrial adenocarcinoma) , HEp-2 (larnyx carcinoma), Hs-5787 (breast carcinoma), K-562 (chronic myelogenous leukemia), SF-188 (brain carcinoma), SNU-1 (stomach carcinoma) and WiDr (colon carcinoma) . We investigated growth inhibition of solvent (EtOH, MeOH) and water (100$^{\circ}C$, 121$^{\circ}C$) extracts from Korean red ginseng by clonogenic assay. The results of clonogenic assay showed that EtOH extract had growth inhibition against Calu-3, SF-188 and SNU-1, MeOH extract had growth inhibition against Calu-3, Hs-5787, K-562, and WiDr, but water extract at 100$^{\circ}C$ and water extract at 121$^{\circ}C$ had not growth inhibition against used cell lines.

• Bulletin of the Korean Chemical Society
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• 제35권1호
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• pp.129-134
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• 2014

Two series of SAHA-liked hydroxamate analogues were designed, synthesized and evaluated for their biological activities against nuclear HDACs. Compounds of Series I were found to be very effective inhibitors of cancer cell growth in the PC-3, Hut78, K562 and Jurkat E6-1 cancer cell lines with mean $IC_{50}$ values from $0.54{\mu}M$ (Ic, Jurkat E6-1) to $7.73{\mu}M$ (Ib, K562), indicating that they are cell permeable and the benzimidazolyl-based ligands are flexible enough to occupy the binding site of HDAC.