• Journal of the Korean Institute of Landscape Architecture International Edition
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• no.1
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• pp.1-12
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• 2001

The biotope network of Susung gu is characterized as dense residence zones forming its core that enable partial biotope in and around the residential zones. First, in district I, it is possible to make these zones connected to the third district. In district II, which is abundant in biotope, it is very important not to continue destoyi9ng the existing biotopes. In the case of district III, old residence zones have fill the severe gap between forests and the Sinchun river, through redevelopment, which covers more than 30% of the biotope area with large scaled linear residence areas. In the case of district IV, limited destruction of biotope and the improvement of nature areas were suggested as the alternative for preservation of biotopes. Consequently, in the construction of the biotope network in Su-sung gu, the maintenance of existing biotopes is required. Int he old residence zones, as redevelopment occurs, by maintaining biotope area of more than 30% and making the scale of residential complexes more than 1ha, it is possible for old residence zones to accomplish the role of providing important green spaces. In the case of newly developed residential zones, by reducing the rate of pavement of traffic conducts, utilizing small sized parks at the junctions and the plantation of trees along the corridors, the entire residence zones are able to accomplish the role of providing important green space. The problem houses and connecting the inner green space of the private houses with the green spaces of the streets in some areas. Futhermore, green spaces of forests must not be used for urban development. Dual planting on sidewalks, planting plots dispersed among streets and median strips must be established on road, too.

• Molecules and Cells
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• v.43 no.1
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• pp.58-65
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• 2020

Fat mass and obesity-associated (FTO) gene helps to regulate energy homeostasis in mammals by controlling energy expenditure. In addition, FTO functions in the regulation of obesity and adipogenic differentiation; however, a role in osteogenic differentiation is unknown. This study investigated the effects of FTO on osteogenic differentiation of C3H10T1/2 cells and the underlying mechanism. Expression of osteogenic and endoplasmic reticulum (ER) stress markers were characterized by reverse-transcriptase polymerase chain reaction and western blotting. Alkaline phosphatase (ALP) staining was performed to assess ALP activity. BMP2 treatment increased mRNA expression of osteogenic genes and FTO. Overexpression of FTO increased expression of the osteogenic genes distal-less homeobox5 (Dlx5) and runt-related transcription factor 2 (Runx2). Activation of adenosine monophosphate-activated protein kinase (AMPK) increased FTO expression, and there was a positive feedback loop between FTO and p-AMPK. p-AMPK and FTO induced mild ER stress; however, tunicamycin-induced severe ER stress suppressed FTO expression and AMPK activation. In summary, FTO induces osteogenic differentiation of C3H10T1/2 cells upon BMP2 treatment by inducing mild ER stress via a positive feedback loop with p-AMPK. FTO expression and AMPK activation induce mild ER stress. By contrast, severe ER stress inhibits osteogenic differentiation by suppressing FTO expression and AMPK activation.

• The Journal of Korean Physical Therapy
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• v.16 no.4
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• pp.129-141
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• 2004

The purpose of Lumbar Stabilization is to recover the ability of regulating movement of muscular strength, which currently becomes an essential approach to the treatment for lumbago. Sling exercise is a dynamic exercise and a method of active exercise for the patients to take part in their own treatment. This research is to develop the correlation between Lumbar Stabilization and muscular strength as well as Sling exercise. The subjects of this experiment are 12 healthy and normal male and female lasting for 4 weeks. EMG and Postural Med were used as measuring apparatuses. After experiment of 4 weeks exercises, there was not a meaningful result in the measured result of EMG(P>0.05), But there was a significant increase in the result of Postural Med after the experiment(P<0.05). According to this result, we can find out that there is a significant correlation between Sling exercise and muscular strength as well as Lumbar Stabilization. The increase in the lumbar region augments Lumbar Stabilization and the reaction speed of muscle power. So it recovers the stabilization of spine. This Sling exercise program is efficient for the treatment and prevention of back pain.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.475-486
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• 2020

The purpose of present study is to identify the regional tourism resources using Webometric network analysis. The study focuses on Suseong area in Daegu metropolitan city. Various kinds of web-based data, for example, hit counts, online news, and public comments, were used to discover hot places and people's responses. The research question is, 'First, what is the optimum level of the search engine for suseong? Second, what is the online appearance of tourist resources in suseong? Which region is the center of tourism with high levels of emergence? Third, what are the main contents of news articles and comments related to the Suseong pond?'. The results show that the search engine optimization level in Suseong is lower than that in other areas in Daegu. In other words, tourism information and contents regarding Suseong are not highly visible on cyber space. Importantly, Suseong pond had the highest online presence. A close analysis of both online news and users' comments on Suseong pond, however, revealed the biggest concern as calling for improving public accessibility to tourism infrastructure. The findings are expected to contribute to policy development and service operation related to tourism resources in Suseong.

• East Asian mathematical journal
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• v.27 no.4
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• pp.391-415
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• 2011

Mathematics is to reflect on your or other people's psychological mathematic activities. Thus, learners need to reflect on their mathematical activities in order to cultivate mathematical thinking attitude and perceive learning contents. For this study, first of all, two classes of the fifth grade (29 students in experimental group and 31 students in control group) in 'Y' elementary school in Dae-gu city were selected as research targets and post-test of learning achievement and mathematical attitude examination were carried out in order to verify the differences of learning achievement and mathematical attitudes between experimental and control groups. The findings of this study mean that students' learning achievement and mathematical attitudes can be improved by applying mathematical reflective activities to the actual class.

• Journal of the Korean association of regional geographers
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• v.14 no.4
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• pp.367-381
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• 2008

The purpose of this paper is to analyze the change in the distribution and hierarchical structure of commercial land use. Tools for analyzing the spatial structure are index of concentration, coefficient of localization and location quotient. This research is applied to Daegu, focusing on the period 1985-2003. During the 1985-2003 period, the growth rate of commercial land use volume amounted to 330%, compared with a population growth rate of 118%. The biggest component of commercial land use is the retail sector. As the lodging, medical, transportation-warehouse and entertainment sectors have the propensity for concentration and comprise the specialized commercial areas in the suburbs, the other sectors arc evenly distributed. Jung-gu has functioned as a downtown core in the hierarchical structure of commercial areas. So, in the structure of commercial land use, Daegu has continued to be a single nuclear structure. But, Dongdaegu Station influence area has evolved into the second order center since 2000. This is the sign of change in spatial structure from single-nuclear pattern to multi nuclear pattern.

• Journal for History of Mathematics
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• v.33 no.3
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• pp.135-154
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• 2020

This paper tries to show the formation of 'Kyungpook School' that is a nickname given to mathematicians of Kyungpook National University (KNU). In the early period, the role of professor Park Jung-gi was the most important drive to set the research tradition. He made Korea's first english journal in mathematics, Kyungpook Mathematical Journal KMJ which became a cornerstone for students to join the international academic community. Professor Ki U-hang published the most amount of papers in Korea in 1970s and became a role model for young scholars. In this background, KNU's Topology and Geometry Research Center at KNU was chosen as the only Science Research Center in mathematics in 1989, and KNU's mathematicians could get a long-period support for capable mathematics researchers' community.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.6 no.5
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• pp.9-20
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• 2003

The purpose of this study is to construct a database for landscape ecological planning with evaluation and analysis of structure of biotope of city center area for the preservation of species and biotope examining Jung-gu district of Daegu Metropolitan City which is the most extremely and rapidly urbanizing area. The assumption of this study is that the biotope structure of a city center area would be different from the other city area. The results of this study were as follows. 1) The results of the biotope type classification is that there were 11 biotope type groups and 41 detailed biotopes. 2) The primary evaluation is the process for grading general value of classified biotope types, and the result of primary evaluation is that there were 5 biotope types that were greater than third grade besides the biotope type of artificial riverbank with abundant green high water level land. The first grade of biotope type have not appeared in this area, however the fifth grade of biotope type have appeared total of 19 biotope types with the biotope type of the general shopping area with scarce green fields. 3) The secondary evaluation is the process for searching biotopes which are special value, and the result of secondary evaluation is that there were 2 biotopes for la, 7 biotopes for 1b, 2 biotopes for 2a, 1 biotope for 2b and there was no biotope for 2c, and for example, la is the large area that has many magor biotope site in terms of the living space. 4) Finally. scientific method for biotope type classification, the derailed investigation plan of high value biotope and the improvement plan based on the biotope map of city center area must be continued.

• Herbal Formula Science
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• v.31 no.4
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• pp.231-243
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• 2023

Objectives : Jasminum officinale L. var. grandiflorum is used as a traditional or folk remedy in China to treat arthritis, hepatitis, duodenitis, conjunctivitis, gastritis, and diarrhea. In this study, we aimed to study the hepatocyte protective activity and molecular mechanism of Jasminum officinale L. var. grandiflorum aqueous extract (JGW) using HepG2 hepatocyte cell lines. Methods : HepG2 cells were pretreated with diverse concentrations of JGW, and then the cells were exposed to tert-butyl hydroperoxide (tBHP) for inducing oxidative stress. Hydrogen peroxide (H₂O₂) production, glutathione (GSH) concentration, mitochondrial membrane potential (MMP) and cell viability were measured to investigate hepato-protective effects of JGW. Phosphorylation of AMP-activated protein kinases (AMPK), acetyl coenzyme A carboxylase (ACC) and effects of compound C on cell viability were examined to observe the role of AMPK on JGW-mediated cytoprotection. Results : Pretreatment with JGW (10-300 ㎍/mL) significantly suppressed cytotoxicity induced by tBHP in a concentration dependent manner and reduced the expression of cleaved PARP and cleaved caspase-3 proteins related to apoptosis in HepG2 cells. In addition, pretreatment with JGW significantly prevented the increase in H₂O₂ production, GSH depletion, and lower MMP induced by tBHP. Treatment with JGW (30 minutes of incubation and concentrations of 100 and 300 ㎍/mL) increased the phosphorylation of AMPK and ACC and treatment with compound C, a chemical inhibitor of AMPK, inhibited the cytoprotective effect of JGW. Conclusions : Our results demonstrated that JGW may protect hepatocytes from oxidative stress via activation of AMPK.

• Journal of Digital Convergence
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• v.19 no.8
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• pp.33-42
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• 2021

As smartphone-based tourism platforms have become active, policy establishment and service enhancement using review data are being made in various fields. In the case of the preceding studies using tourism review data, most of the studies centered on domestic tourists were conducted, and in the case of foreign tourist studies, studies were conducted only on data collected in some languages and text mining techniques. In this study, 3,515 review data written by foreigners were collected by designating the "Daegu attractions" keyword through the online review site. And LDA-based topic modeling was performed to derive tourism topics. The spatial approach through global and local spatial autocorrelation analysis for each topic can be said to be different from previous studies. As a result of the analysis, it was confirmed that there is a global spatial autocorrelation, and that tourist destinations mainly visited by foreigners are concentrated locally. In addition, hot spots have been drawn around Jung-gu in most of the topics. Based on the analysis results, it is expected to be used as a basic research for spatial analysis based on local government foreign tourism policy establishment and topic modeling. And The limitations of this study were also presented.